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Respiratory
Pathology
94
Pathology
Graduate
01/17/2014

Additional Pathology Flashcards

 


 

Cards

Term
types of emboli
Definition
fat, air, thrombus, bacteria, amniotic guild
Term
emboli that can lead to DIC
Definition
amniotic
Term
emboli from long bone fracture
Definition
fat emboli
Term
CP, tachypnea, dyspnea
Definition
PE
Term
PE imaging
Definition
helical CT
Term
virchow's triad
Definition
stasis, hypercoagulability, endothelial damage
Term
homan's sign
Definition
dorsiflexion of foot -> tender calf
Term
reid index
Definition
gland depth / total thickness of bronchial wall
Term
blue bloater
Definition
chronic bronchitis
Term
chronic bronchitis qualifications
Definition
cough > 3 months in >2 years
Term
pink puffer
Definition
emphysema
Term
smoking vs A1AT def emphyesma
Definition
smoking= centriacinar
A1AT = panacinar
Term
how do emphysema pts prevent airway collapse?
Definition
exhalation through pursed lips
Term
Reid index in chronic brochitis
Definition
>50%
Term
fidings in asthma
Definition
curshcmann's, charcot leiden crstals, smooth mm hypertrophy
Term
curshmann's spirals
Definition
shed epithelium from mucous plugs
Term
charcot-leiden crystals
Definition
eisoinphilic inflammation
Term
asthma diagnosis
Definition
methacholine challenge
Term
physical findings of asthma
Definition
cough, wheezingg, tachypnea, dyspnea, dec I/E ratio, pulsus paradoxus, mucus plugging
Term
bronchiectasis
Definition
chronic necrotizing infection of bronchi -> permanently dilated airways, purulent sputum, recurrent infections, hemoptysis
Term
infection in bronchietasis
Definition
aspergillosis
Term
a/w bronchil obstruction
Definition
bronchiectasis
Term
poor breathing mechanics with restrictive lung dx
- poor mm effort
- poor structural apparatus
Definition
- polio, myasthenia gravis
- scoliosis, morbid obesity
Term
interstitial lung diseases
Definition
ARDS, NRDS, pneumoconiosis, sarcoidosis, idiopathic pulmonary fibrosis, Goodpasture's, wegener's, eosinophilic, drugs
Term
what drugs can causes restrictive lung disease?
Definition
bleomycin, busulfan, amiodarone
Term
caplan's syndrome
Definition
rheumatoid arthritis with coal miner's lung
Term
sandlbasting
Definition
silicosis
Term
inc susceptibility to TB
Definition
silicosis
Term
eggshell calcification of hilar lymph nodes
Definition
silicosis
Term
pneumoconiosis with
- no inc CA risk
- inc CA risk
Definition
- coal miner's and silicosis
- asbestosis
Term
causes of asbestosis
Definition
shipbuilding, roofing and plumbing
Term
pneumoconiosies
- upper lobes
- lower lobes
Definition
- coal miners and silicosis
- asbestosis
Term
golden-brown fusiform rods resembling dumbbells
Definition
asbestosis
Term
mechanism of NRDS
Definition
surfactant deficiency; L:S < 1.5
Term
risk factors for NRDS
Definition
prematurity, maternal DB, C section
Term
tx of NRDS
Definition
maternal steroids before birth, artificial surfactant; thyroxine
Term
causes of ARDS
Definition
trauma, sepsis, shock, aspiration, uremia, pancreatitis or amniotic fluid embolism
Term
ARDS hiso findings
Definition
protein rich leakage into alveoli -> hyaline membrane
Term
cause of damage in ARDS
Definition
initial damage 2/2 release of Nt substances toxic to alveolar wall, activation of coat cascade and ROS
Term
hallmark lab of COPD
Definition
FEV1/FRC < 80%
Term
hallmark lab of restrictive lung dx
Definition
dec TLC, normal FEV1/FVC
Term
central sleep apnea
Definition
no respiratory effor
Term
obstructive sleep apnea
Definition
respiratory effort against airway obstruction
Term
OSA a/w
Definition
besity, loud snoring, systemic/pulmonary HTN, arrhythmias and possibly sudden death
Term
tx OSA
Definition
weight loss, CPAPA, surgery
Term
bronchial obstruction:
- breath sounds
- resonance
- fremitus
- trachea
Definition
- absent or dec
- dec
- dec
- toward
Term
pleural effusion
- breath sounds
- resonance
- fremitus
- trachea
Definition
- dec over effusion
- dullness
- dec
- N/A
Term
pneumonia
- breath sounds
- resonance
- fremitus
- trachea
Definition
- bronchial breath sounds over lesion
- dullness
- inc
- N/A
Term
tension pneumothorax
- breath sounds
- resonance
- fremitus
- trachea
Definition
- dec
- hyperresonant
- absent
- away
Term
spont pneumothorax
- breath sounds
- resonance
- fremitus
- trachea
Definition
- dec
- hyperresonant
- dec
- toward
Term
coin lesion on XR
Definition
lung CA vs granuloma
Term
complications of lung CA
Definition
SVC syndrome, pancoast, horner's, endocrine, recurrent laryngeal symptoms, effusions
Term
central location
Definition
small cell and squamous cell
Term
ACTH
Definition
small cell
Term
ADH
Definition
small cell
Term
cells in small cell
Definition
kulchitsky = small dark blue
Term
lambert-eaton
Definition
small cell
Term
responsive to chemo
Definition
small cell CA
Term
inoperable
Definition
small cell
Term
peripheral location
Definition
adenocarcinoma, large cell
Term
nonsmokers and females
Definition
bronchial
Term
peasants like pneumonia
Definition
bronchioalveola
Term
can result in hypertrophic osteoarthrpathy
Definition
bronchioalveolar
Term
clara cells
Definition
broncial and bronchioalveolar
Term
linked to smoking
Definition
small cell and shamus
Term
PTHrP
Definition
squamous
Term
keratin pearls
Definition
squamous cells
Term
less responsive to chemo
Definition
large cell
Term
removed surgically
Definition
large cell
Term
pleomorphic giant cells with leukocyte fragments in cytoplasm
Definition
large cell
Term
secretes serotonin
Definition
carcinoid tumor
Term
carcinoid syndrome
Definition
flushing, diarrhea, wheezing and R sided Heart lesions
Term
hemorrhagic pleural effusions and pleural thickening
Definition
mesothelioma
Term
psammoma bodies with lung CA
Definition
mesothelioma
Term
pancoast tumor
Definition
CA in apex effecting cervical sympathetic plexus -> horner's
Term
horner's syndrome
Definition
ptosis, miosis anhidrosis
Term
SVC syndrome
Definition
obstruction of SV impairs blood drainage of head and upper extremities
Term
CNS problems in SVC syndrome
Definition
can raise ICP which presents with HA and dizziness and can inc risk of aneurysm/rupture of cranial arteries
Term
organsisms in lobar pneumonia
Definition
s pneumo, klebsiella
Term
consolidation
Definition
lobar
Term
bronchopneumonia organisms
Definition
S aureus, H flu, klebsiella, S pyogenes
Term
patchy distribution involving >1 lobe
Definition
bronchopneumonia
Term
interstitial pneumonia organisms
Definition
viruses, mycoplasma, legionella, chlamydia
Term
causes of lung absces
Definition
broncial obstruction, aspiration or oropharyngeal contents
Term
pt more susceptible for lung abscess
Definition
alcoholis, and epileptics
Term
organisms in lung abscess
Definition
S aureus or anaerobes (bacteroides, fusobacterium, peptostreptococcus
Term
hypersensitiviey pneumonitis
Definition
type III/IV; ag -> dyspnea, cough, chest tightness, HA
Term
transudate
Definition
dec protein
Term
transudate pleural effusion causes
Definition
CHF, nephrotic syndrome, hepatic cirrhosis
Term
exudate
Definition
inc protein content
Term
causes of exudative pleural effusion
Definition
malignancy, pneumonia, collagen vascular dx, trauma
Term
lymphatic pleural effusion
Definition
chylothorax; milky inc in trig
Term
cause of spent pneuothorax
Definition
rupture of apical blebs
Term
causes of tension pneumothorax
Definition
trauma or lung infection; air can enter pleural space but not exit
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