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Respiratory
Pharm
44
Medical
Post-Graduate
03/02/2013

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Term
Epinephrine Hcl

(adrenalin cl)

"Fight or Flight response"
Definition
"True adrenergic drug"

works on all 3 receptor sites--most dangerous due to this stimulation (one of the strongest bronchodilators,anti-arrhytmic

used in codes for jump starting heart & increasing BP
Term
Aminophylline Methylxanthine

derivative of Theophylline
Definition
bronchodilator for asthma

systemic (directly thru body-blood stream)management drug/caffeine like

side effect:NVD (nausea,vomiting,diarhea),palpatations,cardiac arrhythemia
Term
Chromolyn Sodium (Intal)
Definition
mast cell stabilizer

prevents bronkospasm

prophylactic mgment use only-won't work as rescue drug (if having attack will still have wheezing)

one of the least toxic drugs for asthma mgmnt
Term
Isoetharine (Bronkosol II)
Definition
(B2 strong) agonist (weak B1)

adrenergic bronchodilator

relaxed bronchial smooth muscle;stimulates mucociliary action;some inflammatory mediator release
Term
dialation
Definition
production of cAMP
Term
corticosteroids
Definition
drug used to decrease inflammation in asthma patients
Term
3 paths of bronchodilators
Definition
1. Alpha

2. Beta 1 - cardiac

3. Beta 2 - lungs
Term
bronchodilation
Definition
the stimulation of adrenergic drugs
Term
Epinephrine
Definition
drug that mimics the adrenergic nervous system
Term
management of chronic bronchospasm
Definition
use of Xanthines
Term
pharmacokinetic phase
Definition
time required for drug absorption, action and distribution in the body
Term
vasoconstriction
Definition
alpha stimulation
Term
what must be done after inhaling a steroid
Definition
must rinse mouth to prevent fungal infection
Term
side effects
Definition
other then desired effects

can be either good or bad
Term
what must be ordered with a mucomist drug
Definition
bronchodilator
Term
what are some mucolytics that break down bonds in mucus chain
Definition
1. Dornase Alpha

2. Acetyclsteine

3. sodium bicarbinate
Term
what is largest dose of metaproternol
Definition
.3cc
Term
what is tolerance
Definition
decreased or increased response to drug in its dosage form
Term
what is Heparin
Definition
blood thinner
Term
what is Isotonic Saline
Definition
same salt content as in your body

normal saline
Term
what is norepinephrine
Definition
the transmitter site from neurons

sympathetic response
Term
what is a classic beta blocker drug
Definition
Inderal
Term
name two anticholinergics
Definition
Atropine

Atrovent
Term
when is Racemic Epinephrine used
Definition
relief of croup & epiglottis in children

relief of subglottic edema swelling in post extubation
Term
what are mucokinetic drugs
Definition
decreased viscosity of pulmonary secretion

increased production

wetting agents
Term
name the ACLS drugs that can be instilled down ET tube when there is no other access
Definition
A tropine
L idocaine
I suprel
E pinephrine
N arcan

V alium, V ersed
Term
what are three adrenergic receptors
Definition
Alpha - vasoconstriction

Beta 1 - cardiac strength

Beta 2 - lungs bronchodilation
Term
what is pharmacodynamic phase
Definition
mechanism of action in which a drug causes therapeutic effect
Term
what is pharmaceutical phase
Definition
method by which a drug is delivered to the body
Term
what is acetylcholine
Definition
parasympathetic response
Term
Tetracycline
Definition
can kill both gram+ & gram- organisms

wide spectrum antibiotic of antimicrobial activity antiribosomal

Tx PNA (treat pneumonia)
Term
what is the efficacy in regards to drugs
Definition
does the drug do what its suppised to do?

is it working right to get best response?
Term
mannitol
Definition
osmotic diuretic-with low toxicity & short 1/2 life

this interferes with H2O reabsorption in loop of Henle, so give K+ for fluid electrolyte rebalance

can be used in adjusting pH & decreasing intracranial pressure (breaks thru the blood/brain barrier)
Term
what are the side effects of a bronchodilator drug
Definition
palpatation;tachycardia;hypertension;anxiety;weakness;dizziness
Term
what works to inhibit phosphdiesterace & increases levels of CAMP
Definition
anticolergins (Theophylline & aminophylline)
Term
name three mechanisms to promote dilation
Definition
1. beta agonist drugs
2. phosphodieshease inhibitor
3. anticholergeric
Term
what is a xanthine
Definition
anticholenergic drug given in the parasympthetic to block the phosphodiesterase mechanism
Term
what is the pharmacodynamic phase
Definition
mechanism of action by which a drug causes its theraputic effect
Term
what happens in the pharmaceutical phase
Definition
a drug is delivered to the body through different routes of administration & drug form
Term
what are two types of mediator antagonists
Definition
1. mast cell inhibitors
2. Leukotrine inhibitors
Term
what do mucolytics do
Definition
disrupt the mucus molecule to facilitate secretion removal
Term
what wetting agents are used in bland aerosols
Definition
1. isotonic saline
2. hypotonic saline
3. hypertonic saline
4. distilled saline
Term
what do mast cell inhibitors do
Definition
prevent the degranulation of cells & thus the inflammatory events are prevented
Term
what do Leukotrine inhibitors do
Definition
blocks stimulation of leukotrine receptors & blocks bronchoconstriction
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