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Respiratory
Generic/ class
46
Pharmacology
Professional
06/15/2010

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Cards

Term
3 major concerns with chronic pulmonary diseases
Definition
bronchoconstriction-asthma
Mucos hypersecretion-COPD
Mucosal inflamation-asthma and COPD
Term
Irritants cause what type of release
Definition
histamine
Term
Histamine cause what in combo with pulmonary diseases
Definition
More inflammation
More mucus production
Term
Goblet cells produce what
Definition
Mucus
Term
Tracheobroncial tree is made of what muscle
Definition
smooth
Term
What type of shape does the Tracheo tree have
Definition
double helix
Term
What classes of drugs relax bronchial smooth muscle
Definition
B2 agonists
methylxanthines
anticholinergics
Term
What classes of drugs inhibit the release of mediators
Definition
Corticosteroids
Antihistamines
Term
What drugs are bronchodilators that are B2 agonists
Definition
albuterol/ Proventil
metaproterenol/ Alupent
terbutaline/ Breathair
Term
What drug is a non selective bronchodilator
Definition
epinephrine/ Adrenaline
Term
Methylxanthines bronchodilator drugs are
Definition
theophylline/ TheoDur
aminophyllin/ Breathair
Term
Anticholinergic bronchodilators
Definition
atropine
ipratropium bromide/ Atrovent
Term
Anti-inflammatory agents/drugs are classified as what
Definition
Glucocorticoids

aka Steroids
Term
Glucocorticoids that are injected
Definition
methylprednisolone/ Solu-Medrol
dexamethasone/ Decadron
hydrocortisone/ Solu-Cortef, Cortisol
Term
Sympathomimetic bronchodilators that are nonselective alpha and beta are
Definition
epinephrine/ Adrenaline
racemic epinephrine/ Vaponefrin, Micronefrin
Term
Sympathomimetic bronchodilator that is a non selective beta 1 and beta 2
Definition
isoproterenol/Isuprel
Term
What is the sympathomimetic bronchodilator B2 selective prototype
Definition
albuterol/ Proventil
Term
Name some sympathomimetic bronchodilators
Definition
epinephrine/ Adrenaline
albuterol/ Proventil, Ventolin
isoproterenol/ Isuprel
terbutaline/ Breathair
racemic epinephrine/ Vaponefrin
levalbuterol/ Xopnex
isoetharine/ Bronkosol
Term
racemic epinephrine is usually given for what specific respiratory disorder
Definition
Croup- barking cough

C.I. for epiglottitis
Term
What is the MOA for Sympathomimetic bronchodilators
Definition
Relaxing of smooth muscle causing bronchodilation
Stimulation of B2 receptors
Term
Desired effect of the sympathomimetic bronchodilators
Definition
Bronchodilation with
^ HR
anxious
Palpatations
Light headed
Term
When PT has hx of what do we need to use caution using sympathomimetic bronchodilators
Definition
Any type of cardiovascular hx, use cation
side effects
Term
When giving a albuterol treatment and it is not working what type of drugs might the pt be taking at home
Definition
Beta blockers
Term
What are the Methylxanthine bonchodilators
Definition
theophylline/ Theo-Dur
aminophylline/ Aminophylline
Term
What are the side effects of methyl-xanthines remember they act like caffine and chocolate
Definition
^ HR
mild diuretic
^ CNS- wakes you up
Term
What 2 bronchodilators are anticholinergics
Definition
atropine
ipratroprium/ Atrovent
Term
In what other ways besides bronchodilation do parasympatholytic drugs help difficulty breathing pt's
Definition
v respiratory secretions
Term
In what type of patient do you not want to give a parasympatholytic
Definition
pneumonia/ Respiratory infections
Term
How do the corticosteroids help with respiratory problems
Definition
Reduce inlammation
v swelling
Term
Steroids make use more responsive to what other types of drugs
Definition
Sympathomimetic bronchodilators
make airway muscles more responsive
Term
What causes inflammation in the airway
Definition
Histamines:
dilates blood vessels
swelling
Term
What type of drugs do we use to inhibit histamine response
Definition
Antihistamines

diphenhydramine/ Benadryl
Term
How do antihistamines act in the body
Definition
Compete with histamines at the receptor site
Term
what pt's are antihistamines contraindicated for
Definition
Asthma and COPD attacks
Term
Want to thin respiratory secretions and allow pt to expectorate them what drug do we use
Definition
Mucolytics
Term
What is the name of the Mucolytic
Definition
acetylcysteine/ Mucumyst
Term
acetylcysteine/ Mucomyst is also used for what type of overdose
Definition
acetaminophen/Tylenol
Term
What is another name for paralytic's or that we use to paralyze patients
Definition
Nueromuscular blocking agent
Term
What is the name of the depolarizing paralytic
Definition
succyncholine/ Anectine
Term
What are the name of the contractions you get when using RSI on a Pt
Definition
facsiculations
last about 30-60 seconds
Term
Which nuerotransmitter is being blocked with those nueromuscular blocker
Definition
ACH
Term
What are the names of the non depolarizing nueromuscular blockers
Definition
vecuronium/ Norcuron
pancuronium/ Pavulon
rocuronium/ Zemuron
Term
When would we use a non-depolarizing paralytic
Definition
they last longer than depolarizing agents
Term
When using a paralytic what other class of drug do you have to give at the same time
Definition
Sedative
Versed!!!
Term
Facilitating intubation means what
Definition
conscious sedation
Term
If wanting to use conscious sedation what classes of drugs do I use
Definition
Sedative and Muscle relaxant
diazepam and etomidate
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