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Respiratory System
Ch. 22 Moore ARC
66
Physiology
Undergraduate 2
04/13/2013

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Term
3 secondary functions of the Res. system
Definition
Buoyancy (float in water)
Vocalization
Respiratory pump
Term
Upper Res. track consist of
Definition
nasal cavity, paranasal sinus, pharynx
Term
Lowe Res. track consist of
Definition
larynx, trachea, bronchi, bronchioles, alveoli
Term
Res. airways consist of
Definition
Res. brinchioles, alveolar ducts, alveolar sacs, alveoli
Term
through the ___ is where the air is warmed, humidified, and filtered. (mainly from Res. mucosa
Definition
conducting airways
Term
what locations contain PSCC (5)
Definition
nasal cavity, nasopharynx, larynx, trachea, bronchi
Term
Nasal cavity filters and cleans air how?
Definition
Nasal hairs trap large particles, mucus traps smaller particles, seromucous glands secrete lysozyme (antibacterial enzyme), epithelial cells secrete defensins (antibiotic)
Term
the superior nasal cavity and conchae are lined w/ what?
Definition
olfactory epithelium
Term
Differentiate between rhinitis and sinusitis.
Definition
Term
what is laryngitis?
common causes?
Definition
Term
submucosa is what kind of tissue?
contains what?
Definition
DI CT
seromucous glands
Term
Right lungs has how many lobes and segments
Definition
3 lobes
10 segments
Term
Left lung has how many lobes and segments
Definition
2 lobes
8-9 segments
Term
how many terminal bronchioles per bronchopulmonary segment?
Definition
6500
Term
anything less than 1mm are considered?
Definition
bronchioles
Term
in the res. system smooth muscle is controlled by the?
Definition
ANS
Term
PNS
Definition
bronchoconstriction via Ach on muscurinic receptors.
Term
SNS
Definition
bronchodialation via E/NE on beta2 receptors
Term
walls of ea. lung are surrounded by serous membrane, which attaches to the ____
Definition
thorax
Term
the serous membrane of the lungs surrounds the entire lung except for the ___
Definition
lung root
Term
ea. lung is attached to the mediastinum by a ____
Definition
lung root
Term
Lobules are separated by
Definition
interlobular septa (fibrous CT)
Term
how many alveoli per lung? provide how much surface area?
Definition
150 million
100 sq. ft.
Term
what do the alveolar pores do?
Definition
equalize pressure and provide alternate routes to air flow to alveoli that have obstructed airways.
Term
elastic fibers on alveoli do what?
Definition
provide stretch and recoil
Term
the alveolar wall is made up of
Definition
simple squamos epithelium, formed by type 1 alveolar cells.
Term
3 layers of res. membrane
Definition
type 1 alveolar cells
endothelial cells
basement membrane
Term
the endothelial cells of a capillary produce the enzyme called ____. Why is this the ideal location for this blood enzyme?
Definition
ACE.
???
Term
purpose of pulmonary blood
Definition
gas exchange and to nourish Res. membrane
Term
the visceral pleura lines the
Definition
surface of the lungs
Term
the parietal pleura lines the
Definition
inner surface of thoracic wall
Term
what is Pleurisy?
caused by?
Definition
pleural inflammation, resulting in painful breathing, often caused by pneumonia.
Term
L/R plural cavities are separated by the
Definition
mediastinum
Term
external respiration is diffusion of gases between
Definition
alveoli and pulmonary capillaries
Term
internal respiration is diffusion of gases between
Definition
systemic capillaries and cells
Term
4 steps of collective respiration
Definition
pulmonary respiration
external respiration
transport
internal respiration
Term
Boyles Law
Definition
P1V1=P2V2

(high Vol= Low pressure) or
(low Vol = high pressure)
Term
Pneumothorax is
Definition
a hole in the thorax allowing air to enter the pleural cavity.
Term
atelectasis is
Definition
a collapsed lung due to air entering the pleural cavity.
Term
Atm pressure is
Definition
760mmgh
Term
inspiration quiet breathing
Definition
+ thoracic vol.
- Pa (-1mmHg) via contraction of inspiratory muscles.
+ diaphragm
+ external intercostals
Term
expiration quiet breathing
Definition
- thoracic vol.
+ Pa (+1mmhg) via recoil of lungs
- diaphragm
- external intercostals
Term
inspiration forced breathing
Definition
recruit accessory respiratory muscles, to elevate and + circumference of ribcage.
Term
expiration forced breathing
Definition
recruit accessory muscles.
depress and - circumference of ribcage, abdominal ,muscles, raise diaphragm.
Term
Bronchocontriction is mediated by the __. Ach and _____ receptors.
Definition
PNS
muscarinic
Term
what can you do to help long term of bronchocontriction?
Definition
treat w/ E or other Beta 2 agonist. (albuterol) cortical steroid.
Term
Bronchodialation is mediated by the ___/. ___ and Beta 2 receptors.
Definition
SNS
E/NE
Term
What is IRDS stand for?
Definition
Infant respiratory distress syndrome
Term
what is IRDS?
How do you treat it?
Definition
problem in infants not producing enough surfactant, so they have difficulty inflating their lungs.
Treatment: synthetic surfactant &/ or mechanical ventilator.
Term
Poor lung compliance results in what?
Disease example?
Definition
amount of surfactant produced is decreased.
elastic tissue is replaced w/ fibrosis tissue.
Example: TB
Term
what is lung compliance?
Definition
how easily a the lungs can be expanded. healthy lungs are super stretchy.
Term
Minute ventilation
Definition
(Vm)= RR x TV= amount of air moving through the respiratory track per min.
TV normal 500ml at rest
RR normal 12/min
Term
Alveolar ventilation
Definition
(Va)= (RR) x (TV-DSV) (dead space vol)
Va= (12) x (500-150)
Term
OPD is?
disease examples?
Definition
easier to breath in than out.
COPD
chronic bronchitis
emphysema
Term
chronic bronchitis is
Definition
inflammation of air ways
+ mucus, and airway thikening, coughing.
Term
Emphysema is
Definition
lunf damage & inflammation of alveoli
destruction of alveolar walls and elastic tissue. - surface area.
Term
RPD is?
disease examples?
Definition
hard to get air in, easier to get air out.
- lung compliance, due to loss of elastic CT
examples: kyphosis, TB, asbestosis, rheumatoid arthritus.
Term
gas diffusion between alveoli and pulmonary blood is _____ respiration
Definition
external respiration
Term
gas diffusion between blood and tissues is ____ respiration.
Definition
internal respiration
Term
Daltons Law of PP
Definition
Total pressure of gas mixture= sum of individual gas pressures. this is called partial pressure.
Term
Henrys Law of dissolved gas
Definition
amount of gas movement. gases dissolve into/out of a liquid in proportion to PP graident.
Term
Ficks law of diffusion
Definition
Rate= (SA)(Delta P)(D)/ T
D= solubility.
T= thickness
Term
PP of O2 in the atm=
goes up or down in higher altitudes?
Definition
.209 x 760mmgh= 159mmgh
goes down
Term
PP of O2 in alveoli=
why is it smaller?
Definition
.137 x 760mmgh= 104mmhg
smaller PO2 due to mixing, and increase water vapor.
Term
Arterial PO2=
Definition
100mmhg
Term
Alveolar PO2+
Definition
104mmhg
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