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Respiratory System
Chapter 15-Essentials of Anatomy and Physiology
67
Biology
Undergraduate 2
12/10/2012

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Term
Functions of the Respiratory System
Definition

1) Gas exchange

2) Move air to/from gas exchange surfaces of lungs

3) Protect from dehydration, temp changes, pathogens

4) Communication

5) Aid sense of smell

Term
Respiratory Tract-Conducting Portion
Definition
entrance to nasal cavity->large bronchioles. Filters, warms and humidifies air Protect alveoli from debris, pathogens, extremes Lined by respiratory mucosa
Term
Respiratory Mucosa
Definition
Lines conducting portion.
Respiratory epithelium(ciliated columnar epithelium with mucous cells and glands)
Term
Nasal Conchae
Definition
Project out of nasal cavity.
Air swirls around conchae, particles stick to mucous coating.
Promote filtration, extra time for warming/humidifying
Term
Parasanal Sinuses
Definition
Produces mucous that clears respiratory surfaces of nasal cavity.
Term
Pharynx
Definition
AKA throat. Chamber shared by digestive and respiratory systems. 3 Subdivisions- Nasopharynx, Oropharynx, Laryngopharynx -Materials entering digestive tract pass through both oropharynx and laryngopharynx
Term
Nasopharynx
Definition
Lined by typical respiratory epithelium.
Pharyngeal tonsil, entrance to auditory tubes
Term
Oropharynx
Definition
Between soft palate and base of tongue.
Palastine tonsil
Stratified squamous epithelium
Term
Laryngopharynx
Definition
To esophagus entrance.
Stratified squamous epithelium
Term
Larynx
Definition
AKA voice box Enter through glottis 9 carilages 3 largest- epiglottis, thyroid cartilage, cricoid cartilage
Term
Epiglottis
Definition
Closes glottis during swallowing
Term
Thyroid Cartilage
Definition
Anterior and lateral surfaces
Adams apple
Term
False Vocal Cords
Definition
ligaments, inelastic. Prevent foreign objects from entering glottis, protect true cords
Term
True Vocal Cords
Definition
Elastic ligaments between thyroid and arytenoid cartilages.
Vibrated by air passing through glottis
Term
Trachea
Definition
AKA windpipe Supported by 15-20 C-shaped Tracheal cartilages
Term
Tracheal Cartilages
Definition
C shaped
Prevent trachea collapse/overexpansion
allow food masses to pass through esophagus
Ends connected by tracheal is muscle(smooth muscle)-contractions(autonomic), adjust diameter.
Sympathetic stimulation increases diameter
Term
Bronchi
Definition
Trachea-->right and left primary bronchi
ciliated epithelium, C-shaped cartilaginous rings
Right=larger, steeper angle
Term
Secondary Bronchi
Definition
After primary bronchus enters lung. Secondary Bronchi enter lobes of lung
Term
Tertiary Bronchi
Definition
9-10 in each lung
Supplies air to specific region (Bronchopulmonary segment)
Term
Bronchiole
Definition
Cartilages disappear completely
Walls dominated by smooth muscle (autonomic nervous system)
control resistance to airflow, distribution of air in lungs
Term
Bronchodilation
Definition
Sympathetic activation-->smooth muscle relax, diameter increases
Term
Bronchoconstriction
Definition
Parasympathetic stimulation--Asthma=extreme response, block passageways
Term
Terminal Bronchioles
Definition
Supply air to a lobule of the lung
Term
Lobule
Definition
Segment of lung tissue bounded by CT partitions, supplied by single bronchiole
Term
Respiratory Bronchioles
Definition
Terminal bronchiole divides within lobe Thinnest branches, deliver air to gas-exchange surfaces Open into alveolar ducts
Term
Alveolar Sacs
Definition
common chambers contacted to multiple individual alveoli-the exchange surface of the lungs
Term
Pneumocytes type I
Definition
Simple squamous epithelium cells in alveoli
Thin.
Term
Alveolar Macrophages
Definition
Roaming, patrol epithelium
Phagocytize particles
Term
Pneumocytes type II
Definition
Septal Cells Produce surfactant
Term
Surfactant
Definition
Oily secretion onto alveolar surfaces.
Keeps alveoli open by reducing surface tension
Term
Respiratory Membrane
Definition
1) Squamous epithelial cells lining alveoli
2) Endothelial cells lining adjacent capillary
3) Fused basement membrane inbetween
Term
Diffusion across Membrane
Definition
Rapid because short distance
O2 and CO2 are lipid soluble, can move between blood and alveolar air
Term
Angiotension-Convertin Enzyme (ACE)
Definition
Produced by endothelial cells of alveolar capillaries
Term
Pulmonary Embolism
Definition
Blockage of a branch of pulmonary artery will stop blood flow to a group of lobules/alveoli
Term
Lungs
Definition
Right lung has 3 lobes, Left has 2
Term
Pleural Cavity
Definition
Surrounds each lung Lined by pleura, serous membrane Parietal pleural-inner surface of body wall visceral pleura-outer surface of lungs Secrete pleural fluid to reduce friction
Term
External Respiration
Definition
Processes involved in exchange of O2 and CO2 between interstitial fluids and external enviornment
To met respiratory demands of cells
Term
Internal Respiration
Definition
Absorption of O2 and release of CO2 by cells
Term
Pulmonary Ventilation
Definition
Physical movement air air in and out
Respiratory Rate-number of breaths/minute
Term
Pressure Gradient
Definition
Air flows from high pressure to low pressure
Any expansion/contraction of thoracic cavity directly affects lung volume
Term
Diaphragm
Definition
Floor of thoracic cavity
When relaxed, compresses lungs.
Contract, increase volume of cavity & expands lungs
Term
Rib Cage
Definition
Rib cage elevation increases cavity volume with help from external intercostal muscles&accessory muscles
Internal intercostal muscles and accessory muscles lower rib cage
Term
Compliance
Definition
Indication of how easily the lungs expand.
Lower compliance, greater force required to fill and empty the lungs
Greater compliance, easier to fill
Term
Quiet Breathing
Definition
Inhalation is active-contraction of diaphragm and intercostal muscles
exhalation is passive
Term
Forced Breathing
Definition
Inhalation and exhalation are active
Term
Tidal Volume
Definition
At rest, the amount of air you move into or out of lungs during a single respiratory cycle
Can be increased through forced breathing
Term
Expiratory Reserve Volume
Definition
In a normal, quiet respiratory cycle. Amount of air that could be voluntarily expelled
Term
Inspiratory Reserve Volume
Definition
Amount of air that can be taken in over and above the tidal volume
Term
Vital Capacity
Definition
IRV+ERV+Tidal Volume
Max amount of air that can be moved into and out of respiratory system in a single cycle
Term
Residual Volume
Definition
Amount of air that remains in lungs even after max exhalation.
Because lungs are held against thoracic wall
Term
Minimal Volume
Definition
Amount of air left in respiratory system when chest cavity has been penetrated and lungs collapse
Term
Partial Pressures of Gasses
Definition
Partial pressure of each gas determines its rate of diffusion between alveolar air and the bloodstream
The Pp of O2 determines how much O2 enters solution but has not effect on diffusion rates of N2 or CO2
Term
Respiratory Reflexes
Definition
Induced changes in response to information from mechanoreceptors and chemoreceptors
Term
Mechanoreceptor Reflects
Definition
Respond to changes in lung volume/changes in arterial bp
Term
Inflation Reflex
Definition
(Mechanoreceptor)
Prevents lungs from overexpanding in forced breathing
Stretch receptors stimulated when lungs expand
Volume of lung increases, DRG inspiratory center is inhibited, VRG expiratory center is stimulated
->inhalation stops as lungs near max volume
-->active exhalation
Term
Deflation Reflex
Definition
Inhibits expiratory center, stimulates inspiratory center when lungs are collapsing
Term
Herring-Breur Reflex
Definition
Inflation and deflation reflexes
Neither involved in normal quiet breathing

Blood pressure falls, respiratory rate increases b/c of carotid and aortic baroreceptors
Term
Chemoreceptor Reflexes
Definition
Respond to chemical changes in blood and cerebrospinal fluid Stimulation-
Term
PCO2
Definition
More powerful effect on respiratory activity than O2
Small increase in PCO2 stimulates CO2 receptors, PO2 does not decline enough to activate O2 receptors
CO@ levels=responsible for regulating respiratory activity
**2 types of receptors work together when PO2 does fall
Term
Involuntary Respiratory Centers
Definition
In medulla oblongata and pons
Regulate respiratory muscles, control respiratory rate and breathing depth
Respond to sensory information
Term
Voluntary Respiratory Centers
Definition
Activity in cerebral cortex that affects output of respiratory centers/motor neurons
Term
Respiratory Centers
Definition
3 pairs of nuclei in pons and medulla oblongata
Influenced by elevated body temps, CNS stimulants
Term
Respiratory Rhythmicity Centers
Definition
of Medulla oblongata
set pace for respiration
Term
Dorsal Respiratory Group (DRG)
Definition
Respiratory center
contains a inspiratory center
Term
Ventral Respiratory Group (VRG)
Definition
Respiratory center
Contains an expiratory center
Term
DRG inspiratory center
Definition
functions in EVERY respiratory cycle
Neurons control external intercostal muscles and the diaphragm
Maintain basic rhythm even in absence of sensory/regulatory stimuli
Term
VRG expiratory center
Definition
Only during forced breathing, activates accessory muscles
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