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Respiratory System
BrownMed
80
Medical
Graduate
09/11/2010

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Cards

Term
Three Parts of Respiratory System
Definition
Ventilation, Conduction, Gas Exchange
Term
Skeletal Muscles involved in Ventilation
Definition
Diaphragm, Intercostal Muscles, Abdominal Muscles
Term
What part of the body is involved in conduction?
Definition
Respiratory airways/tubes (nasal cavity, pharynx, larynx, trachea, bronchi, bronchioles, terminal bronchioles)
Term
Where does gas exchange take place?
Definition
Alveolar-blood interface
Term
Emryological origin of respiratory system?
Definition
Endodermal diverticulum of the foregut (an epithelial tube that undergoes branching morphogenesis)
Term
Function of conducting portion
Definition
transport air to the alveoli to filter, clean, moisten, and warm or cool
Term
anatomic dead space
Definition
conducting portion
Term
what lines the conducting portion of the respiratory system?
Definition
"respiratory epithelium" -- pseudostratified ciliated columnar epithelium with goblet cells
Term
Elements of the conduit system below larynx
Definition
smooth muscle (for constriction) and elastic fibers (for recoil)
Term
conduit system from larynx to bronchi contains what kind of cartliage in their walls
Definition
complete or incomplete rings of hyaline cartilage
Term
what part of the respiratory tree does not contain cartilage?
Definition
the parts that are distal to the bronchi
Term
bronchi branch into?
Definition
bronchioles, then terminal bronchioles, and finally respiratory bronchioles
Term
what makes up the gas exchange portion of the system?
Definition
respiratory bronchioles, alveolar duct and associated alveolar sacs and alveoli
Term
adventitia
Definition
outermost connective tissue covering of any organ, vessel, or other structure
Term
lamina propria
Definition
thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa (mucous membrane)
Term
the respiratory tract is a series of tubes with
Definition
an epithelial lining, a lamina propria, connective tissue with glands (and sometimes cartilage), smooth muscle, and adventitia containing connective tissue.
Term
Are there goblet cells in the the respiratory bronchioles, alveolar duct, or alveolar sac + alveoli?
Definition
No
Term
turbinates
Definition
also called conchae. incomplete plates of bone that divide each chamber of the nose into three smaller chambers (superior, middle, and inferior)
Term
lining of middle and inferior chambers of the nose
Definition
respiratory epithelium
Term
lining of superior chamber of the nose
Definition
epithelium containing specialized olfactory (smell) receptors (olfactory epithelium)
Term
nasal cavity and paranasal sinus are lined by
Definition
a mucous membrane that consists of pseudostratified ciliated columnar epithelium with goblet cells
Term
what is muco-ciliary clearance?
Definition
mucous traps debris and the cilia sweep the mucous posteriorly to the pharynx where it is swallowed or expectorated
Term
how is air humidified?
Definition
by the addition of moisture from the mucous membrane
Term
where is air warmed?
Definition
in the nasal cavity before it passes into the pharynx
Term
swell bodies
Definition
large thin-walled vascular venous plexuses contained in the lamina propria of the conchae that engorge periodically on alternate side of the nose. also warm inspired air
Term
olfactory cells
Definition
bipolar neurons that span the entire length of the epithelium
Term
what is in the highly specialized sensory epithelium that lines the olfactory region?
Definition
neurons and supporting cells
Term
perikaryon
Definition
cell body
Term
the apical part of of an olfactory cell
Definition
modified dendrite with long (non-motile) cilia
Term
sustentacular cells
Definition
support cells
Term
where is the nasopharynx?
Definition
uppermost part of pharynx
Term
what lines the nasopharynx?
Definition
pseudostratigied ciliated epithelium (respiratory epithelium)
Term
paranasal sinus
Definition
air-filled pockets in facial bones around nasal cavity
Term
maxillary
Definition
paranasal sinus located in each cheek
Term
ethmoid
Definition
6-12 small paranasal sinuses per side located between the eyes
Term
frontal
Definition
one paranasal sinus per side, located in the forehead
Term
sphenoid
Definition
one paranasal sinus per side located in the forehead
Term
ostium
Definition
an opening in sinuses that connect to the nasal cavity
Term
what lines paranasal sinuses?
Definition
respiratory epithelium (though thinner epithelium and fewer goblet cells)
Term
functions of larynx
Definition
phonation (formation of sounds) and control of air pathway (to ensure no food)
Term
major structures of larynx
Definition
epiglotti, thyroid, cartilage, cricoid cartilage, bilateral arytenoid cartilages
Term
what lines epiglottis?
Definition
stratified squamous on upper (lingual) surface. lower (laryngeal) is respiratory epithelium
Term
support for epiglottis
Definition
plate of vascularized connective tissue surrounding elastic cartilage core, surrounded by perichondrium
Term
another name for false vocal cords
Definition
vestibular or ventricular folds
Term
what separates false vocal cords from true vocal cords?
Definition
laryngeal ventricle
Term
where are the false vocal cords and true vocal cords located?
Definition
mucosa of the larynx
Term
what lines the upper larynx?
Definition
stratified squamous epithelium
Term
what lines the true vocal cords?
Definition
stratified squamous
Term
true vocal cords consist of
Definition
stratified squamous epithelium, vocal ligament (connective tissue with elastic bundles) and vocal muscles (skeletal)
Term
false vocal cords consist of
Definition
respiratory epithelium, lamina propria (with exocrine gland and lymphatic nodules
Term
what provides support and protection for the larynx?
Definition
plates of hyaline cartilage
Term
what lines the trachea?
Definition
respiratory epithelium
Term
where does the trachea start and end?
Definition
larynx to bifurcation of two primary bronchi
Term
where are the 16-20 C shaped ventral hyaline cartilage rings?
Definition
in the lamina propria of the trachea
Term
do bronchi have c-shaped or o-shaped rings?
Definition
o-shaped
Term
as the bronchi divide, the hyaline cartilage form this instead of rings of cartilage
Definition
what is irregular plates?
Term
primary bronchi divide into
Definition
smaller secondary (or lobar) bronchi
Term
tertiary bronchi supply
Definition
bronchopulmonary segments (~10/lung)
Term
do bronchioles contain cartilage?
Definition
no
Term
do bronchioles have glands?
Definition
no
Term
what lines larger bronchioles?
Definition
respiratory epithelium
Term
what lines smaller bronchioles?
Definition
ciliary columnar and then cuboidal cells
Term
clara cells
Definition
non-ciliated secretory cells -- dome-like cells that are located between ciliated cells. unknown function. secrete GAGs
Term
what lines respiratory bronchioles?
Definition
thin non-ciliated simple cuboidal epithelium (clara cells) that transition into squamous at the respiratory bronchiole/alveolar duct junction
Term
respiratory bronchioles have a layer of this beneath the mucosa
Definition
smooth muscle
Term
what is a respiratory bronchiole in close association with?
Definition
a pulmonary artery
Term
functional unit of the lung (primary lobule) includes
Definition
alveolar ducts, atria, alveolar sacs, and alveoli
Term
what is the support for alveolar ducts and for alveoli?
Definition
a matrix of elastic and collagen fibers
Term
atria or alveolar sac
Definition
terminal portion of alveolar duct opens to here
Term
alveoli
Definition
sac-like structure at final part of bronchial tree
Term
why are adjacent alveoli connected by small pores?
Definition
to help equalize air pressure between them
Term
what is the alveolar wall composed of?
Definition
endothelial cells of blood capillaries (continuous and non-fenestrated), squamous type I epithelial cells, and secretory (type II) alveolar cells
Term
alveolar type I pneumocytes
Definition
simple squamous epithelial cells, ~97% of lining, attached by desmosomes and zonula occludens
Term
type II pneumocytes
Definition
cuboidal and have osmiophilic lamella bodies containing phospholipids, GAGs, phosphatidyl choline, and sphingomyelin.
Term
osmiophilic lamellar bodies contain which important substance?
Definition
surfactant
Term
what does surfactant do?
Definition
it coats alveolar linings and lowers surface tension to zero (preventing alveolar collapse)
Term
two layers of surfactant
Definition
hypophase (proteinaceous aqueous basal layer) and phospholipid phase (dipalmitoyl lecithin)
Term
another name for alveolar macrophages?
Definition
dust cells
Term
what do dust cells do?
Definition
remove debris from lumen and from interstitium
Term
Who is the coolest kid in the class?
Definition
Grayson
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