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Respiratory Physiology (p.50 to the end of lecture)
Flashcards that start at the material for exam 2
55
Nursing
Graduate
06/14/2014

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Cards

Term
Dead Space
Definition
inspired air that does not reach the alveoli
Term
What are the three types of dead space?
Definition
* 1) Anatomic
* 2) Alveolar
* 3) Physiologic
Term
Anatomic Dead Space
Definition
the amount of air in the conducting airways
Term
The amount of anatomic dead space is equal to what?
Definition
2 ml/kg
Term
During inspiration, what happens to the “fresh gas" and “non-fresh gas"?
Definition
They are mixed within the in the conducting airways.
Term
Minute Alveolar Ventilation
Definition
MV= (TV - deadspace) x RR
Term
What impacts minute alveolar ventilation?
Definition
1) Depth of volume
2) respiratory rate
Term
Which is more effective at increasing minute ventilation (decreasing PaCO2), increasing tidal volume ore respiratory rate?
Definition
Tidal Volume
Term
Apnea
Definition
No spontaneous ventilation
Term
Eupnea
Definition
Normal spontaneous breathing
Term
Hyperpnea
Definition
Increased volume but unchanged rate
Term
Biots
Definition
Short episodes of rapid uniform deep inspiration followed by 10-30 seconds of apnea
Term
Hyperventilation
Definition
Increase alveolar ventilation (either rate, volume, or both) causing PaCO2 to decrease.
Term
Hypoventilation
Definition
Decrease in alveolar ventilation (either due to rate, volume, or both) causing a rise in PaCO2.
Term
Cheyne Stokes
Definition
10-30 seconds of apnea then very fast volume and rates, then gradual decline and apnea.
Term
Kussmaul
Definition
Increased depth and rate (diabetic ketoacidosis)
Term
Orthopnea
Definition
Inability to breath unless in the upright position
Term
Tachypnea
Definition
Rapid rate
Term
Dyspnea
Definition
Difficulty breathing (conscious awareness of). Dyspnea is a subjective component used to describe “the feeling that you are not getting enough air”.
Term
Alveolar Dead Space
Definition
defined as “alveoli that are ventilated but not perfused”
Term
Can you calculate alveolar dead space?
Definition
No
-Here is what the powerpoint said:

The amount of dead space is “difficult to calculate” and “cannot be calculated because it is unpredictable”
Term
Physiologic Dead Space
Definition
Sum of anatomical and alveolar dead space
Term
Capnography
Definition
"Measures the presence of CO2 (patency) and quantifying CO2"
Term
At what point in the respiratory cycle is EtCO2 measured? (inspiration or expiration)
Definition
Expiration ("This point best represents CO2 in the alveoli or lower airways.")
Term
Does EtCO2 and PaCO2 correlate in healthy individuals?
Definition
Yes
Term
Does EtCO2 mix with air in the conducting pathways?
Definition
Yes
Term
Tidal Volume
Definition
Volume of air inspired or expired with each normal breath (500ml)
Term
Inspiratory Reserve Volume
Definition
Extra volume of air that can be inspired over and above the normal tidal volume (3000ml)
Term
Expiratory Reserve Volume
Definition
Extra volume of air that can be forcefully expired after a normal exhaled tidal volume (1100ml)
Term
Spirometry
Definition
Is a means to measure various volumes in the lungs.
Term
Residual Volume
Definition
Volume of air that remains after forceful expiration (1200ml)
Term
Vital Capacity (equation)
Definition
IRV + TV + ERV (4800ml)

Inspiratory Reserve Volume + Tidal Volume + Expiratory Reserve Volume
Term
Vital Capacity (explained in words)
Definition
It is the amount of volume that can be expelled from the lungs after first taking a very deep breath (4800ml)
Term
Another name for Vital Capacity
Definition
Sometimes called the Forced Vital Capacity (FVC)
Term
Functional Residual Capacity (equation)
Definition
ERV + RV

expiratory reserve volume + residual volume
Term
Functional Residual Capacity (explained in words)
Definition
Amount of volume left in the lungs after normal expiration
Term
Why is the functional residual capacity important in anesthesia?
Definition
b/c it is the amount of volume (and is located in the area of the lungs) where much of the air exchange is occurring
Term
What can reduce the functional residual capacity?
Definition
Displacement of the diaphragm and pushing abdominal contents upward in all of the following situations:

-supine position
-trendelendburg position
-obesity
-compression on the abdomen
-belly insufflation
Term
Inspiratory Capacity
Definition
TV + IRV

Tidal Volume + Inspiratory Reserve Volume
Term
Pulmonary Function Tests
Definition
measure the amount of forced expired volume (FEV) in1 second to the total Forced Vital Capacity (FVC), this ratio gives us a percentage
Term
What is a normal FEV-1/FVC?
Definition
80% (meaning that you can forcibly exhale 80% of FVC in 1 second)
Term
What sex are all of the standard lung volumes based on?
Definition
Males ("in women the volumes are appoximately 20% less)
Term
Functional Residual Capacity (2nd definition in words found in the lecture)
Definition
also defined as the volume in which inward lung elastic recoil= the outward chest wall recoil
Term
What 5 Factors impact functional residual capacity?
Definition
1. Body habitus:
* FRC is directly proportional to height. Obesity greatly decreases FRC (loss of chest compliance)

2. Sex:
FRC is > in males compared to females

3. Posture
FRC decreases as pts are moved from upright to supine or prone position due to decreased lung compliance from abdominal contents pushing upward against the diaphragm
* Greatest change occurs between 0-60 degrees, with no additional change in the head down position of up to 30 degrees (?)

4. Lung Disease:
decreases FRC due to decreased of the lung, chest, or both.

5. Diaphragmatic Tone:
In anesthesia, "muscle relaxants stop the diaphragm from working”.
Term
What can measure basic lung volumes?
Definition
Spirometry
Term
What gas law does plethysmography use?
Definition
Boyle's Law
Term
Plethmysmography, how does it work?
Definition
* Test subject is placed in a sealed chamber with a mouthpiece
* At the end of normal expiration, the mouthpiece is closed
* Pt makes an inspiratory effort
* As pt tries to inhale, the lungs expand, decreasing lung pressure and increasing lung volume
* This causes a pressure increase in the chamber, since it is a closed system, and the volume of the body compartment has increased
* Temperature and pressure remain constant, volume changes
Term
Closing capacity
Definition
the volume at which the small non-cartilaginous airways close during exhalation (these airways rely on volume to keep them open)

-"alveoli in dependent areas will continue to be perfused but not ventilated!"
Term
What is used to measure closing capacity?
Definition
A tracer, like Xenon gas.
Term
Is closing capacity bigger or smaller than FRC?
Definition
Smaller, but it rises with age.
Term
Why does arterial O2 tension decrease with age?
Definition
Because closing capacity rises steadily with age.
Term
By age 44, at what point are CC and FRC equal?
Definition
In the supine position
Term
By age 66, at what point are CC and FRC equal?
Definition
In the upright position
Term
Is Functional Residual Capacity affected by age or position?
Definition
Position
Term
Is Closing Capacity affected by age or position?
Definition
Age
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