Term
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Definition
Abnormally low oxygen in blood, tissues, and or lungs. Leads to decreased organ function and/or cellular damage |
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Term
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Definition
Insufficient blood oxygen levels to meet metabolic requirements |
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Term
3 Goals of respiratory adjustment as a response to hypoxemia |
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Definition
Improve oxygenation Assist in CO2 removal Improve oxygen delivery to tissues |
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Term
4 compensatory signs of respiratory distress |
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Definition
Increased ventilatory drive Increased work of breathing Increased cardiac rate Increased cardiac contractility |
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Term
7 possible signs of ventilatory failure |
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Definition
Use of accessory muscles, intercostal retraction, cyanosis, paradoxical respiration, tachycardia, narcosis, coma |
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Term
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Definition
Bluish-purplish color in the tissues due to an increased amount of deoxygenated hemoglobin |
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Term
What 3 hypoxemic conditions might be difficult to detect cyanosis with? |
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Definition
Shock (due to vasoconstriction) CO2 poisoning (MM appear bright red) Methoglobinemia (MM dark/brownish) |
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Term
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Definition
Inadequate inspired oxygen, Alveolar hypoventilation, ventilation-perfusion mismatch, diffusion impairment, shunt, and abnormal hemoglobin |
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Term
Which causes of hypoxemia respond to oxygen supplementation? |
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Definition
Inadequate inspired O2, ventilation perfusion mismatch, diffusion impairment, some shunts, |
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Term
Which causes of hypoxemia do not respond to oxygen supplementation? |
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Definition
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Term
When does inadequate inspired O2 commonly occur? |
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Definition
High altitude, anesthetic mistakes |
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Term
What is alveolar hypoventilation? |
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Definition
Oxygen flow to the alveoli is decreased |
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Term
What causes alveolar hypoventilation? |
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Definition
neuromuscular failure, increased dead space, airway obstruction, primary pulmonary disease, pleural space disorders, severe brain disorders, muscular fatigue, muscular paralysis |
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Term
What is the most common cause of hypoxemia? |
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Definition
Ventilation-perfusion mismatch |
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Term
Where is the V/Q ratio highest? Lowest? |
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Definition
Top of the lungs, Bottom of the lungs |
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Term
What is the immediate cause of diffusion impairment? |
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Definition
Thickened alveolar barrier |
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Term
What etiologies can cause a diffusion impairment? |
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Definition
Edema, fibrosis, pneumonia, COPD, Neoplasia |
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Term
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Definition
Venous blood bypasses oxygenation in lungs and mixes with arteria blood, deceasing PaO2 |
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Term
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Definition
Collapsed lung lobes, PDA, patent foramen ovale, other ASDs and VSDs |
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Term
Causes of methemoglobinemia |
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Definition
methemoglobin reductase deficiencies, oxidizing agents |
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Term
How should you evaluate airway patency? |
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Definition
Observing breathing pattern- a non-patent airway= prolonged inspiration with little/no air movement |
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Term
4 things to do in respiratory crisis (in order of importance) |
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Definition
Give oxygen, start invasive ventilation measures, catheterize, draw blood |
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Term
3 signs of paradoxical respiration |
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Definition
Inward collapse of intercostal spaces Inward collapse of abdomen Inward movement of ribs (all during inspiration) |
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Term
5 (6?) anatomic locations of respiratory problems |
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Definition
Upper airways, Lower airways, Pulmonary parenchyma, pleural space, thoracic wall (cardiac?) |
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Term
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Definition
High pitched inspiratory noise localized to upper airways |
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Term
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Definition
Snoring/crackling noise associated with the upper airways |
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Term
Clinical signs of upper airway obstruction |
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Definition
stridor, stertor, cyanosis, head/neck extension, orthopnea, exercise intolerance, choking, retching, collapse, clawing at face/neck, honking sounds |
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Term
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Definition
Inability to breath in a recumbent position |
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Term
Clinical sign of lower airway disorders |
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Definition
forceful expiratory effort |
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Term
Clinical signs associated with parenchymal disorders |
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Definition
open mouth breathing, paradoxical resp. cyanosis, nasal flare, coughing, gagging, dyspnea, anxiety, orthopnea, hemoptysis, fever, tachypnea, tachycardia, weakness, depression, anorexia, nasal discharge, panting |
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Term
What signs are associated with pulmonary parenchymal disorders related to congestive heart failure? |
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Definition
Crackles, heart murmurs, and arrhythmias |
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Term
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Definition
Coughing up blood or bloody foam |
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Term
What defines the pleural space? |
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Definition
Visceral and parietal pleurae |
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Term
Why is there normally a small amount of fluid in the pleural cavity? |
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Definition
Allows for low friction sliding of the pleurae and instantaneous volume changes |
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Term
What happens if there is a loss of negative pleural pressure? |
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Definition
The lungs collapse due to elastic recoil |
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Term
Clinical signs of pleural space disorders |
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Definition
short shallow breaths, tachypnea, open mouth breathing, cyanosis, dull lung sounds, auscultable fluid line, muffled cardiac sounds, GI sounds |
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Term
What types of injuries could cause a thoracic wall respiratory disorder? |
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Definition
rib fractures, flail chest, sucking and penetrating chest wounds, neurologic, muscular, and orthopedic disease of the thorax |
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Term
Why might thoracic wall disease, parenchymal, and pleural diseases be closely related? |
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Definition
chest wall injuries can also have pleural effusions, lung contusions, pneumothorax, and hernias associated with them |
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Term
What are some clinical signs of thoracic wall disorders? |
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Definition
Signs of resp. distress, cyanosis, increased chest wall movement, segments of ribs that move independently, lack of abdominal/diaphragmatic movement, lack of intercostal muscle movement. |
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Term
What should serial physical exams assess in patients with respiratory distress? |
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Definition
respiratory rate & effort, mucous membrane color, auscultation, pulse quality, and capillary refill time |
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Term
What is the most objective way to measure oxygenation and ventilation? |
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Definition
Arterial blood gas analysis |
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Term
Besides arterial blood gases, what are other ways to monitor ventilation? |
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Definition
Pulse oximetry and end-tidal CO2 |
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