Term
Respiratory Pharmacology includes
Antitussives
Decongestants
Antihistamines
Mucolytics & Expectorants
and
6 Agents used to treat Asthma, Bronchitis, Emphysema
1. Beta _________ Agonists
2. Xanthine Derivatives
3. Anticholinergics
4. Cromones
5. _______________
6. Leukotriene Inhibitors |
|
Definition
Antitussives
Decongestants
Antihistamines
Mucolytics & Expectorants
and
6 Agents used to treat Asthma, Bronchitis, Emphysema
1. Beta Adernergic Agonists
2. Xanthine Derivatives
3. Anticholinergics
4. Cromones
5. Glucocorticoids
6. Leukotriene Inhibitors
|
|
|
Term
Antitussives
(ex: Robitussin DM)
Action: _________
Therapeutic Effect: Reduces Cough
Side Effects: ___________ |
|
Definition
Action:
Inhibits cough by direct effect on brainstem.
Therapeutic Effect:
Reduces Cough
Side Effects:
Retention of secretions related to cough supression.
|
|
|
Term
Decongestants
(Ex: Sudafed)
Action : ___________
Therapeutic Effect: Reduces local congestion of nasal pathway.
Side Effects: __________ |
|
Definition
Action :
Binds with alpha receptors in blood vessels of the nasal mucosa to stimulus vasoconstriction.
Therapeutic Effect:
Reduces local congestion of nasal pathway.
Side Effects:
Nervousness, increased blood pressure.
|
|
|
Term
Antihistamines
(Ex: Benadryl)
Action: Blocks the action of histamine on upper respiratory tissues.
Therapeutic Effect: Treatment of allergic symptoms.
Side Effects: _______________ |
|
Definition
Action:
Blocks the action of histamine on upper respiratory tissues.
Therapeutic Effect:
Treatment of allergic symptoms.
Side Effects:
Sedation, fatigue, dizziness, nausea.
|
|
|
Term
Mucolytics & Expectorants
(Ex: Robitussin/ Mucomyst)
Action: _________
Therapeutic Effect: Treatment of coughs associated with upper airway infections.
Side Effects: rarely noted, dizziness, nausea. |
|
Definition
Action:
1. Expectorants increases respiratory tract fluids.
2. Facilitate the production and ejection of mucus; mucolytics decrease the viscosity of secretions.
3. Ejection of secretions.
Therapeutic Effect:
Treatment of coughs associated with upper airway infections.
Side Effects:
rarely noted, dizziness, nausea.
|
|
|
Term
6 Pharmacologic agents used to treat/prevent of diseases of airway obstruction
(Asthma, Bronchitis, Emphysema)
1._______ Adernergic Agonists
2. Xanathine Derivatives
3. ________________
4.Cromones
5. Glucocorticoids
6. ___________ Inhibitors |
|
Definition
1.Beta Adernergic Agonists
2. Xanathine Derivatives
3. Anticholinergics
4.Cromones
5. Glucocorticoids
6. Leukotriene Inhibitors
|
|
|
Term
Beta Adrenergic Agonists
This drug has both a Short Acting Beta Agonist (SABA) as well as a Long Acting Beat Agonist (LABA)
Action: __________
Therapeutic Effect: prevents or inhibits airway obstruction in bronchospatic disease.
Side Effects: ______________ |
|
Definition
Action:
1. Short or long term acting stimulation of beta receptors.
2. Relaxation of bronchiole smooth muscles.
Therapeutic Effect: prevents or inhibits airway obstruction in bronchospatic disease.
Side Effects:
Nervousness, shaking, tremors, restlessness, tachycardia, palpitations, paradoxical, bronchospasms.
|
|
|
Term
This will probably be on the exam!!
What is the difference between short acting and long acting beta andrenergic agonists. |
|
Definition
Short Acting = rescue medication
Long Acting = chronic medication |
|
|
Term
Xanthinge Derivatives
Action: ________
Therapeutic Effect: Prevent bronchochonstriction in obstructive airway disease.
Side Effects: Toxicity that presents as nausea, irritability, restlessness. |
|
Definition
Action:
1. Possible blocking of adensosine.
2. Smooth muscle relaxation; possible blocking of phosphodiesterase (PDE)
3. Inhibition of inflammatory response.
Therapeutic Effect:
Prevent bronchochonstriction in obstructive airway disease.
Side Effects:
Toxicity that presents as nausea, irritability, restlessness.
|
|
|
Term
Anticholinergics
Examples:
Ipratropium = Short
Tiotropium = Long
Action: _________________
Therapeutic Effect: Improves airway flow in bronchospastic diseases.
Side Effects: ____________ |
|
Definition
Action:
1. Short or long acting muscarinic receptor blockers.
2. Reduction of acetylcholine induced bronchoconstriction.
Therapeutic Effect:
Improves airway flow in bronchospastic diseases.
Side Effects:
Constipation, dry mouth, blurred vision, urinary retention
CANT SHIT, SPIT, SEE, OR PEE
|
|
|
Term
Cromones
(Mast cell Stabalizers)
Action:
1. Inhibits the release of inflammatory mediators.
2. Reduction of histamine and leukotrienes.
Therapeutic Effect: _________
Side Effects: nasal and upper respiratory tract irritation following inhalation. |
|
Definition
Action:
1. Inhibits the release of inflammatory mediators.
2. Reduction of histamine and leukotrienes.
Therapeutic Effect:
Prophylaxis; prevention of asthma attacks prior to activities that are known to precipitate an asthma attack (exercise, exposure to animal hair)
Side Effects: nasal and upper respiratory tract irritation following inhalation.
|
|
|
Term
Leukotriene Inhibitors
(Ex: Singular)
Action: Reduces the synthesis of leukotrienes or blocks the receptors for leukotrienes.
Therapeutic Effect: ________
Side Effects: Liver dysfuction noted rarely. |
|
Definition
Action: Reduces the synthesis of leukotrienes or blocks the receptors for leukotrienes.
Therapeutic Effect:
Managment of the inflammatory component of bronchoconstrictive diseases.
Side Effects: Liver dysfuction noted rarely.
|
|
|
Term
Glucocorticoids
Action: ________
Therapeutic Effects: Treatment of inflammation associated with hyperresponsive
airways.
Side Effects: __________ |
|
Definition
Action:
Inhibit proinflammatory products (cytokines, prostoglandins, leukotrienes) while increasing antiinflammatory proteins.
Therapeutic Effects: Treatment of inflammation associated with hyperresponsive airways.
Side Effects:
GI bleed, dyspepsia, hyperglycemia, delayed wound healing, osteoperosis, fluid retention, hypertension, "MOON FACE", truncal obesity, acne.
|
|
|
Term
The treatment of Cystic Fibrosis Includes 1 Goal and 5 Pharmacologics
Goal
1. ______ airway patency.
Pharmacologics
1. Bronchodialators
2. __________ and Expectorants
3. Glucocorticoids
4. ____ Infectives
5. Others: ?? |
|
Definition
Goal
1. ______ airway patency.
Pharmacologics
1. Bronchodialators
2. Mucolytics and Expectorants
3. Glucocorticoids
4. Anti Infectives
5. Others: ??
|
|
|
