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RESPIRATORY I
N/A
37
Physiology
Graduate
11/15/2011

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Term
THE NERVOUS SYSTEM ___________ ADJUSTS THE RATE OF _________ VENTILATION ALMOST EXACTLY TO THE BODY'S DEMANDS, THUS ARTERIAL PO2 AND PCO2 ARE HARDLY _________ EVEN WITH MODERATE TO INTENSE EXERCISE OR OTHER RESPIRATORY DISTRESS.
Definition
AUTOMATICALLY

ALVEOLAR
MODIFIED
Term
THE RESPIRATORY CENTER IS COMPOSED OF _______ GROUPS OF NEURONS LOCATED __________ IN THE _____ STEM OF THE CENTRAL NERVOUS SYSTEM (CNS)SPECIFICALLY AT THE BRAIN _________ AND ____.
Definition
SEVERAL
BILATERALLY

MEDULLA OBLONGATA
PONS
Term
DORSAL RESP. GROUP: DORSAL PORTION OF _______ ________. MAINLY ___________.
Definition
MEDULLA OBLONGATA
INSPIRATION
Term
VENTRAL RESP. GROUP: ______________ PORTION OF MEDULLA. ________ OR __________ DEPENDING ON THE _______ STIMULATED.
Definition
VENTROLATERAL
INSP
EXPIR
NERVES
Term
___________ CENTER: __________ LOCATED IN THE PONS. ______ AND _______ OF BREATHING.
Definition
PNEUMOTAXIC
DORSALLY
RATE
PATTERN
Term
THE MOST IMPORTANT ROLE IN CONTROLLING RESP. IS PLAYED BY THE ______ RESP. GROUP WHICH ________ INFORMATION FROM THE ____________, ____________ AND OTHER RECEPTORS IN THE _____ THAT HELP IN THE CONTROL.
Definition
DORSAL
RECEIVES
CHEMORECEPTORS
BARORECEPTORS
LUNGS
Term
THE SIGNAL TRANSMITTED TO THE _________ _________ MUSCLES (DIAPHRAGM AND EXTERNAL INTERCOSTALS) IS A _____ SIGNAL
Definition
PRIMARY INSPIRATORY
"RAMP"
Term
RAMP SIGNAL WHICH STARTS FROM _ AND CONTINUES WITH A STEADY ________ FOR ABOUT _ SECONDS.

STOPS FOR _ SECONDS AND STARTS
AGAIN THUS CAUSING A STEADY ________ IN THE __________ VOL DURING _________.
INSTEAD OF ________ GASPS
Definition
0
INCREASE
2

3
INCREASE
PULMONARY .
INSPIRATION
INSPIRATORY .
Term
THE DURATION OF _________ IS DETERMINED BY THE DURATION OF INSPIRATION.

THE ___________ CENTER
_______ THE DURATION OF _________ AND _________ THE RESPIRATORY RATE.

STRONG SIGNALS FROM THIS CENTER _______ THE ____ OF __________ WHILE _____ SIGNALS INCREASE IT.
Definition
EXPIRATION

PNEUMOTAXIC
LIMITS
INSPIRATION
INCREASES

REDUCE
TIME
INSPIRATION
WEAK
Term
THE ______ GROUP IS MOSTLY INVOLVED IN
________ LEVELS OF __________.
Definition
VENTRAL
INCREASED
VENTILATION
Term
THE ULTIMATE GOAL OF RESP. IS TO MAINTAIN PROPER ___, ___ AND ____ IN
THE _______, SOMETHING ACHIEVED BY THE RESP. _______.
Definition
[H+], [O2] AND [CO2]
TISSUES
ACTIVITY
Term
INCREASED __ AND CO2 ________ STIMULATE THE ________ CENTER CAUSING ________ OF THE _________ AND EXPIRATORY SIGNALS.

__ DOESN’T HAVE A DIRECT EFFECT ON THE CENTER BUT ACTS THROUGH THE _________ __________ LOCATED IN THE _______ ____ __________ ______.
Definition
H+
DIRECTLY
RESP
INCREASE
INSPIRATORY


O2

PERIPH. CHEMORECEPTORS
CAROTID AND AORTIC BODIES.
Term
AFTER FRESH O2 GETS TO THE ALVEOLI, THE NEXT STEP IS ITS ________ INTO THE _________ BLOOD AND ___ IN THE _________ DIRECTION.
Definition
DIFFUSION
PULMONARY
CO2
OPPOSITE
Term
“THE NET DIFFUSION OF A GAS IN ONE DIRECTION IS A ______ EFFECT OF ITS _______ _________” AND ITS
PRESS. ________ A SURFACE IS CAUSED BY THE _________ IMPACT OF ________ ________ MOLECULES AGAINST THAT SURFACE => THE TOTAL PRESS. OF A GAS IS ________ PROPORTIONAL TO THE ___________ OF THE GAS MOLECULES.
Definition
DIRECT
CONC. GRADIENT

AGAINST
CONSTANT
KINETICALLY MOVING
DIRECTLY
CONCENTRATION
Term
AIR => __ % N2 + ___% O2 WITH A TOTAL PRESS. AT SEA LEVEL = ?
Definition
79%
21%
760 mm Hg.
Term
_____ GAS CONTRIBUTES TO THE TOTAL PRESS. IN DIRECT PROPORTION TO ITS ___________.
Definition
EACH
[ ]

I.E. 79% CAUSED BY N2 = 600 mmHg
21% CAUSED BY O2 = 160 mmHg
Term
PARTIAL PRESS. OF N2 (PN2) = ____ ___

PARTIAL PRESS. OF O2 (PO2) = _____ __

TOTAL PRESS.= ?
Definition
600 mmHg
160 mmHg

SUM OF ALL PART. PRESS. PO2, PCO2, PN2, PH2O
Term
GASES DISSOLVED IN H2O OR THE BODY TISSUES ALSO EXERT _________ BECAUSE THE DISSOLVED MOLECULES ARE MOVING __________ AND HAVE ________ ENERGY.

WHEN THEY ENCOUNTER A ________ LIKE THE MEMB. OF A CELL, THE RESULT IS THE SAME.

THE PRESSURE OF A GAS IN A SOLUTION IS DETERMINED NOT ONLY BY ITS ________
BUT ALSO BY THE ___________ COEFFICIENT OF THE GAS.
Definition
PRESSURE
RANDOMLY
KINETIC

SURFACE

CONC
SOLUBILITY
Term
HENRY’S LAW ?
Definition
PRESSURE= DISSOLVED GAS/SOLUBILITY COEFFICIENT
Term
WHEN PRESS. IS EXPRESSED IN ATMOSPHERES (1 atm = 760 mmHg) AND CONC. IN VOLUME OF GAS DISSOLVED IN EACH VOL. OF H2O,
THE SOLUBILITY COEFFICIENT
AT BODY TEMP.: ?
Definition
O2 = 0.024; CO2 = 0.57; CO = 0.018; N2 = 0.012; He2 = 0.008
Term
THE ______ PRESS OF ____ GAS TENDS TO
_____ MOLECULES OF THAT GAS INTO SOLUTION FIRST IN THE __________ MEMB AND THEN IN THE _____ OF THE __________ ___________.

SAME THING HAPPENS CONVERSELY.

THE RATE AT WHICH THEY ESCAPE FROM ONE MEDIUM TO ANOTHER IS DIRECTLY ___________ TO THEIR _________ ________ IN THE ______.

THE NET ________ IS DETERMINED BY THE __________ BETWEEN THE TWO _______ ________.
Definition
PARTIAL
EACH
FORCE

ALVEOLAR .
BLOOD
ALVEOLAR CAPILLARIES

PROPORTIONAL
PARTIAL PRESSURE
BLOOD

DIFFUSION
DIFFERENCE
PARTIAL PRESSURES
Term
IF PARTIAL PRESS. OF A GAS IN THE _________ (O2) IS _______ THAN IN THE BLOOD IT WILL GO TO THE _______.

IF IT'S HIGHER IN THE BLOOD (CO2), IT WILL ESCAPE TO THE ________.

THE NET DIFFUSION OF _____ THROUGH FLUIDS IS CAUSED BY PRESS. DIFFERENCE.
 
THE GAS PRESS. DIFFERENCE BETWEEN TWO AREAS IS KNOWN AS _________ _________ FOR DIFFUSION.
Definition
ALVEOLI
HIGHER
BLOOD

ALVEOLI

GASES

PRESSURE DIFFERENCE
Term
THE ALVEOLAR AIR _______ THE SAME COMPOSITION OF THE ___________ AIR DUE TO:

--ALVEOLAR AIR IS ONLY ___________
REPLACED WITH ______ BREATH
--O2 IS GOING TO THE ______
--CO2 IS ______ FROM THE BLOOD
--____ ATMOSPHERIC AIR THAT ENTERS
THE RESP. PATHWAYS IS
IMMEDIATELY _____________ EVEN
BEFORE REACHING THE _________.
Definition
HASN'T
ATMOSPHERIC

PARTIALLY
EACH

BLOOD
COMING

DRY
HUMIDIFIED
ALVEOLI
Term
PRINT AND MEMORIZE SLIDE 22
Definition
Term
ONLY ____ ml OF AIR IS BROUGHT INTO THE ALVEOLI WITH EACH ______ BREATHING, BEING THE SAME AMT. OF ___ ALVEOLAR AIR _________, IMPLYING THAT ONLY ____% OF THE ______ AIR IS REPLACED BY NEW ATMOSPHERIC AIR WITH EACH _____.   AT A _____ RESPIRATORY RATE (± 12/MIN) IN ABOUT ____ SEC., ______ THE GAS IS REMOVED.   THE _____ REPLACEMENT OF ALVEOLAR AIR IS IMPORTANT BECAUSE IT ______ SUDDEN CHANGES IN THE ________ IN THE BLOOD, MAKING THE RESP. CONTROL MECHANISMS MUCH MORE ______.
Definition
350 ml
NORMAL
OLD
EXPIRED
14
ALVEOLAR
BREATH
NORMAL
17
HALF
SLOW
PREVENTS
[GASES]
STABLE
Term
VENTILATIQN-PERFUSIQN RATIO

NORMAL VALUES:

pO2 IN AIR = ___ (IN NORMAL AIR)
ALVEOLI = _____
VENOUS = _____

pCO2 IN AIR = _____
ALVEOLI = _____
VENOUS = ______
Definition
159 mmHg
104 mmHg
40 mmHg

0.3 mm Hg
40 mmHg
46 mmHg
Term
SLIDE 25
Definition
Term
Va/Q
 
Va = ___________
Q = ____________

THERE COULD BE AREAS WITH GOOD _________ BUT POOR __________ AND AREAS WITH GOOD _________ BUT POOR ________.
Definition
(ALVEOLAR VENTILATION)
(BLOOD FLOW)

PERFUSION
VENTILATION
VENTILATION
PERFUSION
Term
IF Va IS _______ FOR A GIVEN ALVEOLUS AND Q IS ALSO ______ FOR THE SAME ALVEOLUS, THE _____ IS NORMAL.
Definition
NORMAL
NORMAL
Va/Q
Term
SLIDE 27
Definition
Term
IF Va/Q = 0 (NO VENTILATION)
=>PCO2 IS ______ AND PO2 IS ______
THE SAME AS ______ BLOOD

IF Va/Q =  (NO PERFUSION)
PCO2 IS _____ AND PO2 IS _____
THE SAME AS _______ AIR.

IF Va/Q IS NORMAL:
PO2 IS ______: ______ (INSPIRED AIR)
_______ (VENOUS BLOOD)
PCO2 IS ______: _____ (VENOUS BLOOD)
______ (INSPIRED AIR)
Definition
45 mmHg
40 mmHg
VENOUS

0 mmHg
159 mmHg
INSPIRED

104 mmHg
159 mmHg
40 mmHg

40 mmHg
45 mmHg
0.3 mmHg
Term
NOT ALL THE BLOOD GOING TO THE _____ GOES THROUGH THE ALVEOLI,
± __ OF THE ____ WILL GO TO THE ________ VESSELS AND ALSO SOME OF THE BLOOD GOING TO THE ALVEOLI GOES THROUGH ALVEOLI WITH ________ Va/Q RATIO.

THE AMT. OF THIS BLOOD (WHICH IS _____ OXYGENATED) PER ______ IS KNOWN AS
___________ ________ SHOWING
Va/Q = _______ NORMAL.
Definition
LUNGS
2%
CO
BRONCHIAL
ABNORMAL

NOT
MINUTE
PHYSIOLOGIC SHUNT
lower than
Term
IF Va/Q = ____ THAN NORMAL => Va IS GOOD BUT Q IS _____ =>
MORE O2 AVAILABLE THAN CAN BE __________ AND THE VENTILATION OF THESE ALVEOLI IS SAID TO BE _______.

BESIDES, THE VENTILATION OF THE _____ ______ _____ AREAS OF THE RESP. PATHWAYS IS _____ TOO.

THE SUM OF THESE TWO TYPES OF ______ VENTILATION IS KNOWN AS... ?
Definition
higher
LOW
TRANSPORTED

WASTED

ANATOMICAL DEAD SPACE

WASTED
WASTED
PHYSIOLOGIC DEAD SPACE.
Term
ONCE O2 DIFFUSES FROM THE ALVEOLI, IS
TRANSPORTED BY THE BLOOD, COMBINED
WITH HEMOGLOBIN (Hb) WHICH INCREASES THIS TRANSPORT _________ TIMES COMPARED TO SIMPLY _______.
 
PO2 IN ALVEOLI > _____ > ______ AND FOR ___ IS THE OTHER WAY AROUND.
Definition
30 TO 100
DISSOLVED

BLOOD
TISSUES
CO2
Term
WITH EXERCISE, A PERSON WILL REQUIRE AS MUCH AS ___ _____ THE AMT. OF O2 AND THE INCREASE CO => _______ IN THE TIME _______ REMAINS IN THE ___________.

=> BLOOD OXYGENATION _______ BUT THE GREAT SAFETY FACTOR FOR O2 DIFFUSION THROUGH THE ________ ______ MAINTAINS THE BLOOD __________ ________ WITH O2.
Definition
20 TIMES
DECREASE
BLOOD
CAPILLARIES
SUFFERS
PULMONARY MEMB.
ALMOST SATURATED
Term
O2 COMBINES WITH Hb IN A _____ WAY AND WHEN PO2 IS _____ (ALVEOLI)

=> O2 ____ WITH Hb BUT WHEN PO2 IS LOW (TISSUES)

=> O2 IS ______ FROM Hb.
Definition
REVERSIBLE
HIGH

BINDS
RELEASED
Term
PO2 IN ARTERIES IS ± ____ mmHg ,
THE USUAL ____ ____ OF ART. BLOOD IS ± ___%
Definition
95
O2 SAT.
97%
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