Term
|
Definition
reversible airway obstruction (asthma)
b2 agonist at bronchial smooth muscle
tachycardia, tremor, chest pain;
caution CAD, etc |
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Term
|
Definition
asthma
decreased mediator synthesis, release, and
infiltration of inflammatory cells
oropharyngeal candidiasis, dysphonia, some adrenal
suppression, some bone loss, cataract and glaucoma
possible |
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Term
|
Definition
adrenocortical insufficiency, other uses
glucocorticoid > mineralocorticoid
adrenal suppression, hypokalemia |
|
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Term
|
Definition
immunosuppression s/p transplantation
binds cyclophilin, then inhibits calcineurin
required for IL-2 production and T-cell proliferation
binds cyclophilin, then inhibits calcineurin
required for IL-2 production and T-cell proliferation |
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|
Term
|
Definition
immunosuppression s/p transplantation
binds FKBP12, then inhibits calcineurin
required for IL-2 production and T-cell proliferation
infection risk, nephrotoxicity,
neurotoxicity, NVD, hypertension, hyperglycemia;
avoid in pregnancy/lactation; interaction enzyme inhibitors |
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Term
|
Definition
pain associated with inflammation
inhibits cyclo-oxygenase (COX)
GI distress, tinnitus, altered
hemostasis, renal dysfunction; avoid if allergic;
interaction warfarin, corticosteroids, ethanol |
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|
Term
|
Definition
pain associated with inflammation
inhibits cyclo-oxygenase
GI distress, tinnitus, renal
dysfunction; avoid if allergic |
|
|
Term
|
Definition
acute pain, dysmenorrhea, arthritis
inhibits COX-2
dyspesia, abdominal pain; avoid if
allergic; interaction warfarin, lithium
• May be associated with increased cardiac risk (MI, thrombosis) |
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