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Respiratory Agents
a
63
Pharmacology
Undergraduate 2
10/27/2011

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Term
dry powder inhaler (DPI)
Definition
a small device that is activated by the process of inhalation to deliver a fine powder directly to the bronchial tree
Term
turbohaler - rotahaler
Definition
two types of DPI's
Term
antitussives
Definition
type of drug that supresses cough
Term
mucolytic
Definition
directly loosen thick, viscous bronchial secretions by breaking down the chemical structur of the mucous molecules
Term
mast cell stabalizers
Definition
type of drug that inhibits the release of histimines
Term
corticosteroids
Definition
type of drug that supresses inflammation
Term
expectorants
Definition
type of drug that causes mucus produced to be thinner
Term
beta-adrenergic blockers
Definition
type of drug that dialates the bronchi
Term
intranasal glucocorticoids
Definition
type that is the drug of choice in treating allergic rhinitis
Term
secretion
Definition
intranasal glucocorticoids decrease the ______ of inflammatory mediators
Term
2-3 weeks
Definition
it can take _____ of intranasal glucocorticosteroids use for optimum benefits to be attained
Term
glucocorticosteroids
Definition
when delivered by oral inhalation (not intranasal) these can be used to treat asthma
Term
fluticasone (Flonase, Veramyst)
Definition
preferred intranasal glucocorticosteroid
Term
Flovent
Definition
oral inhaler form of flonase intranasal glucocorticosteroid
Term
opiods
Definition
act by raising that cough threshold in the cough center decrease both the frequency and intensity of cough
Term
dextromethorphan
Definition
drug that is chemically similar to the opiods that acts on the CNS to raise the cough threshold
Term
Benzonatate (Tessalon)
Definition
drug that has local anesthetic-like effect on stretch receptors in the lung which interupts the cough message
Term
hypotension, fever, nausea, jerky motions tolegs, coma
Definition
when dextromethorphan is combined with MAOI's it causes (5)
Term
10 days
Definition
notify the dr if cough persists for more than ____
Term
expectorants
Definition
stimulate mucus flow, which thins bronchial secretions allowing them to be removed with less forceful coughing
Term
increase
Definition
expectorants _____ secretion production which allows it to be expelled
Term
Guaifenesin
Definition
expectorants Mucinex and Robitussin contain the active ingrediant ______
Term
Potassion iodide
terpin hydrate
Guaifenesin
Definition
three expectorants
Term
D
Definition
potassium iodide is pregnancy category ___
Term
acetylcysteine (Mucomyst)
Definition
mucolytic that is delivered by the inhalation route and is not available OTC
Term
acetylcysteine (Mucomyst)
Definition
drug used to treat kidney failure and acetaminophen overdose
Term
stomatitis, N/V, fever, drowsy, bronchospasms, bronchiol irritation
Definition
s/e of acetylcysteine (Mucomyst)
Term
status asthmaticus
Definition
severe, prolonged form of asthma that is unresponsive to drug treatment and can cause respiratory failure
Term
terminate
Definition
Beta-adrenergic agents prevent or terminate acute bronchiolspasms
Term
terminate
Definition
Xanthines prevent or terminate acute bronchiolspasms
Term
terminate
Definition
Anticholinergics prevent or terminate acute bronchiolspasms
Term
prevent
Definition
Corticosteroids prevent or terminate acute bronchiolspasms
Term
prevent
Definition
Mast cell stabilizers prevent or terminate acute bronchiolspasms
Term
prevent
Definition
Leukotriene modifiers prevent or terminate acute bronchiolspasms
Term
beta adrenergics
Xanthine derivatives
Cholinergic blockers
Definition
three types of bronchodialators
Term
salmeterol (Serevent)
Definition
preferred long acting bronchiodialator
- is DPI
Term
DPI
Definition
method of delivery for salmeterol(Serevent)
Term
bronchospasms
Definition
excessive overuse of inhalation meds may cause paradoxical _______
Term
beta-adrenergic
Definition
class of bronchodialators that are extremely potent and begin effects w/in 5 min and last up to 4 hours
Term
theophylline
aminophylline
Definition
two Xanthine derivative bronchodialators
Term
xanthine derivatives (Theophylline and aminophylline)
Definition
bronchodialator that stimulates the CNS to promote bronchodialation
- relaxes smooth muscle of bronchi
Term
increase
Definition
macrolides and quinolones will ____ theophylline levels
Term
decrease
Definition
St. john's wort and tobacco will _____ theophylline levels
Term
decrease
Definition
theophylline will cause a _____ in lithium levels
Term
10-20 mcg/ml
Definition
theraputive range for theophylline
Term
sympathomimetics
Definition
Theophylline mimics the effects of _______
Term
cola, coffee, chocolate, charcoal prepared foods
Definition
when taking theophylline, pt should avoid foods that contain xanthine, such as (4)
Term
50-100%
Definition
smokers may need increase theophylline dosage by _____
Term
glucocorticoids
Definition
bronchodialator that is not for immediate relief and must be used on a daily schedule
Term
1-2 weeks, 4-8 weeks
Definition
glucocorticoids will cause an improvement in symptoms within _____ and ____ for max benefits
Term
glucocorticoids
Definition
drugs that "thin" the tissues so o2 can be exchanged at alveoli level
Term
yeast infections
Definition
strict oral hygiene must be follwed with glucocorticosteroids to prevent ________
Term
rinse well
Definition
pts must _____ after inhalation of glucocorticosteroids
Term
mast cell inhibitors
Definition
safe alternative to glucocorticosteroid use
Term
singulair
Definition
preferred leukotriene modifier
Term
inflammatory response
Definition
leukotrienes are mediators of the _____
Term
leukotriene modifier
Definition
used for the management of persistent asthma that can not be controlled with inhaled glucocorticoids or short-acting beta agents
Term
Singular
Zyflo
Definition
two leukotriene modifiers used to prevent and treat chronic asthma in older than 12 year olds
Term
Accolate
Definition
leukotriene modifier used to prevent and treat chronic asthma in 5 yrs and older
Term
Zileuton
Definition
leukotriene modifier that may cause liver damage - watch liver functions
Term
mast cell stabilizers
Definition
drugs used to prevent exercise induced bronchospasms
- treats asthma and allergies
Term
cromolyn
Definition
mast cell stabalizer that is an ampule that is mixed into a glass of water and taken orally
Term
cromolyn salon
Definition
mast cell stabalizer nasal spray that is prescribed for seasonal allergies
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