Term
How is the respiratory system innervated? |
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Definition
-skeletal muscles innervated by somatic efferent nerves
-airway smooth muscle innervated by ANS |
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Term
What stimulates bronchoconstriction? what portion of the ANS is involved (para or symp)? |
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Definition
cholinergic stimulation
parasympathetic |
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Term
What stimulates bronchodilation? what portion of the ANS is involved (para or symp)? |
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Definition
B2 stimulation (epinephrine)
sympathetic |
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Term
What sources of input are involved with innervation of the respiratory system? |
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Definition
1. Sensory input via vagus nerve -stretch receptors, irritant receptors & J receptors
2. Sensory input from skeletal muscles
3. Chemoreceptor input from carotid & aortic bodies (sense Pa2, PoCo2, pH etc)
4. Sensory input from peripheral receptors (pain, stretching of intercostals or diaphragm) |
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Term
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Definition
-monitor blood composition & interstitial volume
-if interstitial pressure increases, J receptors sense it and will increase RR |
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Term
What do peripheral receptors do? |
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Definition
increase RR in response to pain, or cause contraction in response to stretching of the diaphragm or intercostals |
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Term
What do peripheral chemoreceptors do? |
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Definition
Type I trigger APs in in afferent nerves Type II are supportive
-sense tiny changes in increased Pa CO2 or decreased pH and will increase ventilation -increase ventilation moderately in response to decreased Pa O2 |
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Term
What do central chemoreceptors do? |
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Definition
sense P CO2 by detecting a drop in pH of the brain & CSF
-will trigger a big increase in ventilation to maintain pH within a narrow range |
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Term
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Definition
peripheral chemoreceptors that sense changes in Pa CO2 and pH |
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