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Renal
Renal
19
Medical
Graduate
10/02/2010

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Cards

Term
Name the NaK2Cl symport inhibitors. What are these drugs also known as?
Definition
Furosemide (lasix,Bumetanide, Torsemide, Ethacrynic Acid
AKA Loop diuretics and high ceiling diuretics (because they have a large effect)
Term
Type of Drug?
Furosemide
Definition
NaK2Cl Symport Inhibitor (TAL)
Loop Diuretic
Term
Type of drug?
Bumetanide
Definition
NaK2Cl Symport Inhibitor (TAL)
Loop Diuretic
Term
Type of drug?
Torsemide
Definition
NaK2Cl Symport Inhibitor (TAL)
Loop Diuretic
Term
Type of drug?
Ethacrynic Acid
Definition
NaK2Cl Symport Inhibitor (TAL)
Loop Diuretic
Term
Name the Na-Cl symport inhibitors. Where do these drugs work?
Definition
Hydrochlorothiazide, Chlorothiazide, Metolazone, Chlorthalidone.
Work in the early DCT
Term
Type of drug?
Hydrochlorothiazide
Definition
Na-Cl symport inhibitor (early DCT)
Term
Type of drug?
Chlorothiazide
Definition
Na-Cl symport inhibitor (early DCT)
Term
Type of drug?
Metolazone
Definition
Na-Cl symport inhibitor (early DCT)
Term
Type of drug?
Chlorthalidone
Definition
Na-Cl symport inhibitor (early DCT)
Term
Name the Na channel (ENaC) inhibitors. What are these drugs AKA? Where in the nephron do these drugs act?
Definition
Triamterene, amiloride
AKA K-sparing diuretics
Act in the late DCT and collecting duct
Term
Type of drug?
triamterene
Definition
ENaC inhibitor (late DCT and CT)
Term
Type of drug?
amiloride
Definition
ENaC inhibitor (late DCT and CT)
Term
Name the mineralocorticoid receptor antagonists. What are they AKA? Where in the nephron to they act?
Definition
Spironolactone, eplerenone
AKA K-sparing diuretics, aldosterone sparing diuretics
work in late DCT and CT
Term
Type of drug?
sprionolactone
Definition
mineralocorticoid receptor antagonist, works in late DCT and CT
Term
Type of drug?
eplerenone
Definition
mineralocorticoid receptor antagonist, works in late DCT and CT
Term
Name the Na channel inhibitors (ENaC inhibitors) What are these AKA?
Definition
Amiloride, triampterene
AKA K sparing diuretics
Term
Type of drug:
amiloride
Definition
ENaC inhibitor (K sparing diuretic)
Term
Type of drug?
Triampterene
Definition
ENaC inhibitor (K sparing diuretic).
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