Term
|
Definition
| GN, ischemia or malignant HTN |
|
|
Term
|
Definition
| tubulointerstitla inflammation, acute pyelonephritis, transplant rejection |
|
|
Term
|
Definition
|
|
Term
|
Definition
| advanced renal disease/CRF |
|
|
Term
| causes of nephritic syndrome |
|
Definition
| acute post strep GN, RPGN, verger's, alport |
|
|
Term
| can cause both nephritic and nephrotic |
|
Definition
|
|
Term
|
Definition
| FSGS, membranous, minimal chane, amyloidosis, DM |
|
|
Term
acute post-strep
- LM
- EM
- IF |
|
Definition
- lumpy bumpy
- subepithelial humps
- granular IgG, IgM and C3 |
|
|
Term
|
Definition
| hematuria and RBC casts, azotemia, oliguria, HTN, proteinuria <3.5 |
|
|
Term
|
Definition
- crescent mooth shap; fibrin and plasma protiens; linear
- goodpasture, wegener's microscopic polyangiitis |
|
|
Term
|
Definition
| type II HSR, Ab to GBM and alveolar BM |
|
|
Term
|
Definition
- SLE or MPGN
- wire looping
- sub endothelial and sometimes intramem IgG based IC
- granular |
|
|
Term
|
Definition
- mesangial
- mesangial IC
- IgA based IG in mesangium |
|
|
Term
|
Definition
| type IV collagen mutation; nerve disorders, ocular disorders, deafness; X linked |
|
|
Term
|
Definition
| proteinuria >3.5; hyperlipidemia, fatty casts, edema; with thromboembolism and inc risk of infection |
|
|
Term
|
Definition
- segmental scerlosis and hyalinosis
- foot process effacement
- HIV, heroin, obesity, IFN tx, CKD |
|
|
Term
|
Definition
- diffuse capillary and GBM thickning
- spike and dome appearance with sub epithelial deposits
- granular |
|
|
Term
|
Definition
| drugs, infections, SLE, solid tumors |
|
|
Term
minimal change disease
- LM
- EM
- loss |
|
Definition
- normal
- foot process effacement
- loss of albumin |
|
|
Term
| responds to corticosteroids |
|
Definition
|
|
Term
| congo red and apple green |
|
Definition
|
|
Term
|
Definition
| tram track 2/2 GBM splitting caused by mesangial ingrowth; with HBV and HCV, SLE, subacute endocarditis |
|
|
Term
|
Definition
| dense deposits; with C3 nephritic factor |
|
|
Term
DM glomerulonephropathy
- mechanism
- LM |
|
Definition
- NEG of GBM -> inc permeability , thickening; NEG of efferent -> inc GFR -> mesangial expansion
- eosinophilic nodular glomerulosclerosis |
|
|
Term
|
Definition
| hypercalcemia; ethylene glycol (antifreeze) or vit C abuse |
|
|
Term
| cause of ammonium magnesium phosphate stones |
|
Definition
| urease poitive organism or readiolucent bugs = proteus, staph, and klebsiella |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| tx of cystine renal stones |
|
Definition
|
|
Term
|
Definition
| complete or partial urinary tract obstruction, causes dilation up to obstruction and in chronic cases parenchymal thinning |
|
|
Term
|
Definition
|
|
Term
| genetic syndrome with RCC |
|
Definition
| von Hippel-LIndau on chromosome 3 |
|
|
Term
| paraneoplastic syndrome with RCC |
|
Definition
| EPO, ACTH, PTHrP, and prolactin |
|
|
Term
|
Definition
| wilm's, aniridia, GU malformation, mental/motor retardation |
|
|
Term
| most common tumor or urinary tract |
|
Definition
|
|
Term
| causes of transitional cell CA |
|
Definition
| phenacetin, smoking, aniline dyes and cydlophsophamide |
|
|
Term
|
Definition
| fever, CVA tenderness, nausea and vomiting |
|
|
Term
|
Definition
| thyroidization of kidneys; blunted calyx; whit cell casts in urine; vesicoureteral reflux |
|
|
Term
| signs of drug-induced interstitial nephritis |
|
Definition
| pyuria with eosinphils, azoemia 1-2 wks after diuretics, NSAIDs, penicillin, sulfonamides, rifampin |
|
|
Term
| diffuse cortical necrosis |
|
Definition
| acute generalized cortical infarction of both kidneys; combo of vasospasm and DIC |
|
|
Term
ATN
- causes
- casts
- stages |
|
Definition
- ischemia, crush injury, toxins
- granular "muddy brown casts"
- 1) inciting event, 2) maintenance phase = oliguric, 1-3 weeks, hyperkalemia ; 3) recovery phase = polyuric, BUN and Cr fall, hypokalemia |
|
|
Term
| causes of renal papillary necrosis |
|
Definition
| Dm, acute pyelonephritis, phenacetin use, sickle cell anemia and trait |
|
|
Term
prerenal AKI
- causes
- urine osmolality
- urine Na
- FeNa
- serum BUN/Cr |
|
Definition
- hypotension
- >500
- <10
- <1%
- >20 |
|
|
Term
renal AKI
- - causes
- urine osmolality
- urine Na
- FeNa
- serum BUN/Cr |
|
Definition
- ischemia/toxins, acute GN
- <350
- >20
- >2%
- <15 |
|
|
Term
postrenal AKI
- causes
- urine osmolality
- urine Na
- FeNa
- serum BUN/Cr |
|
Definition
- stones, BPH, neoplasia, congenital anomalies with BL
- <350
- >40
- >4%
- >15 |
|
|
Term
| consequences of renal falure |
|
Definition
| Na/H2o retension (CHF pulmonary edema, HTN), hyperkalemia, metabolic acidosis, uremia, anemia, renal osteodystrophy, dyslipidemia, growth retardation and developmental delay |
|
|
Term
|
Definition
| Inc BUN/Cr; nausea and anorexia, pericarditis, asterixis, encephaloathy, platelet dysfunction |
|
|
Term
|
Definition
| failure or VitD hydroxylation; subperiosteal thinning of bones |
|
|
Term
|
Definition
| adulte; bilateral in paeryncyma; HTN, urinary infection , renal failure; polycystic liver disease, berry aneurysms, mitral valve prolapse |
|
|
Term
|
Definition
| infantile, hepatic fibrosis, can lead to potters; HTN, portal HTN and progressive renal insufficiency |
|
|
Term
|
Definition
| cortical and medullary cysts from dialysis |
|
|
Term
|
Definition
| benign; inciental; thin, nonenhancing cortical, fluid filled |
|
|
Term
|
Definition
| fibrosis and progressive renal insufficiency with inability to concentrate urine; small kidney on US; 70% develop stones |
|
|
