Term
|
Definition
| Cuboidal cells with Microvilli, mitochondria and Plasmalemma Infoldings |
|
|
Term
| Histology of the Loop of Henle |
|
Definition
| Cuboidal with Prominent BM |
|
|
Term
|
Definition
| Prominent Basal Plasmalemma infoldings |
|
|
Term
| Histology of the Collecting Duct |
|
Definition
| Cuboidal with distinct cell boarders |
|
|
Term
| What is the cause and complications of Acquired Renal Cystic Disease |
|
Definition
Cause: Dialysis Patients forming Calcium Oxalate Crystal Obstructions
Complications: Hemorrhage or Carcinoma |
|
|
Term
| What is the impact of Glomerular disease on the tubules |
|
Definition
Direct Autoimmune deposition
Fibrosis from ET1, PDGF, TGF-B activating fibroblasts |
|
|
Term
| Appearance of ATN on Biopsy |
|
Definition
| Loss of surface modifications, Swelling, Pyknosis, Karyolysis |
|
|
Term
| How would you identify Mercuric Chloride, CCl4, or Ethylene Glycol poisoning on Biopsy |
|
Definition
Merc: Acidophillic Inclusions
CCl4: Lipid Isudation
Ethylene Gylcol: Oxalate Crystals and Vaculolar degeneration
|
|
|
Term
| Evidence of Chronic Pyelonephritis |
|
Definition
| Tubule dilation(Maybe Thyroidization), broad scarring over a blunted calyx |
|
|
Term
| What are the causes of Renal Papillary Necrosis |
|
Definition
Acute Pyelo esp in Diabetics
Analgesic Nephritis
Sickle Cell |
|
|
Term
| What are the signs of Interstitial Nephritis on biopsy |
|
Definition
| Polymorphous inflammation with eosinophils |
|
|
Term
| What are the ways to differentiate Diabetic Papillary Necrosis and Analgesic Papillary Necrosis and which has a better prognosis |
|
Definition
Diabetic: Consistent Stage, Yellow
Analgesic: Inconsistent Stage, Brown, Calcification
Analgesic has a better prognosis |
|
|
Term
| What are the non renal tumors that may affect the renal interstitium |
|
Definition
Multiple Myeloma
Malignancy causing Hypercalcemia or Hyperuricemia |
|
|
Term
| What is the pathogenesis of Acute Tubular Necrosis |
|
Definition
Tubular Obstruction by Casts
Vasoconstriction from RAAS activation |
|
|
Term
| What regions of the nephron are typically injured by Toxic ATN and Ischemic ATN respectively? |
|
Definition
Toxic ATN: More diffuse Proximal injury
Ischemic: patchy Proximal and Distal injury |
|
|
Term
| Why is it important to diagnose the cause of ATN quickly |
|
Definition
| Can lead to Renal Failure but the process may be completely reversible |
|
|
Term
| What portions of the nephron are affected by the Autosomal Dominant form of Polysitic Kidney Disease and which are affected by the autosomal recessive form |
|
Definition
Dominant: All portions
Recessive: Collecting Ducts |
|
|
