Term
| Characteristics of Nephrotic Syndrome |
|
Definition
Severe Edema
High Proteinuria
Hyperlipidemia/Hyperlipiduria |
|
|
Term
| Characteristics of Nephritic Syndrome |
|
Definition
Edema
Moderate Proteinuria
HPTN
Hematuria |
|
|
Term
| Postinfectious Glomerulonephritis Biopsy Diagnosis |
|
Definition
LM: Diffuse Endocapillary Proliferation, Leukocyte infiltration
Immunoflorescence: Granular IgG, C3
EM: Subepithelial Humps |
|
|
Term
| Goodpasture's Disease Biopsy Diagnosis |
|
Definition
LM: Extracapillary Proliferation, Crescents, Necrosis
Immunoflorescence: Linear IgG, C3
EM: BM Disruption, no deposits |
|
|
Term
| Berger's Disease by Biopsy Diagnosis |
|
Definition
LM: (Silver)Focal Mesangial Proliferation
Immunofluorescence: IgA, C3, IgM, +/- IgG
EM: Dense Deposits in the Mesangium |
|
|
Term
| Likely disease with sIgA nephropathy as well as other peripheral manifestations |
|
Definition
| Henoch-Schonlein's Purpura |
|
|
Term
| What Nephritic Glomerulonephritis presents in younger adults and children? |
|
Definition
|
|
Term
| Most common Nephrotic Syndrome disease in Children/ in Adults |
|
Definition
Children: Minimal Change
Adults: Membranous |
|
|
Term
| Minimal Change Disease by Biopsy Diagnosis |
|
Definition
LM: Normal
Immunofluorescence: Normal
EM: Foot Process loss |
|
|
Term
| Membranous Glomerulonephritis by Biopsy Diagnosis |
|
Definition
LM: Capillary Wall Thickening, (Silver)Subepithelial Deposits
Immunoflorescence: Granular IgG, C3
EM: Subepithelial Deposits |
|
|
Term
| Focal Segmental Glomerulonephritis by Biopsy Diagnosis |
|
Definition
LM: Focal/Segmental Sclerosis or Hyalinosis
Fluorescence: IgM, C3
EM: Foot Process Loss
|
|
|
Term
| Membranoproliferative Glomerulonephritis by Biopsy Diagnosis |
|
Definition
LM: I-Normal, II-Mesangial/Endocapillary thickening, Glomerular BM Thickening
Silver: Tram Tracking
Immunofluorescence:
I-IgG + C3; C1q + C4
II-C3±IgG; no C1q or C4
EM: I-Subendothelial deposits, II-Dense Deposits
|
|
|
Term
| What is the biopsy observation diagnostic of diabetic Glomerulonephritis? What are other possible signs? |
|
Definition
K-W Lesion: Nodular Glomerulosclerosis
Others: Capsular Drop, Fibrin Caps, Arteriolar Sclerosis |
|
|
Term
| What is the Prognosis of Focal Segmental Glomerulonephritis |
|
Definition
Poor Response to Steroids
Transplant recurrance |
|
|
