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Renal 4
Dr. P Test-1
15
Physiology
Graduate
12/01/2010

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Term
What is Plasma Clearance
Definition
volume of plasma cleared of a particular substance per minute
Term
what is the (normal) plasma clearance of glucose? sodium? waste?
Definition
zero
low
high
Term
what is the equation for plasma clearance?
Definition
(urine concentration of substance)(urine flow rate)/plasma concentration of substance
Term
what is the unit for clearance rate?
Definition
ml/min
Term
if the macula densa cells detect high levels of sodium, what do they secrete?
Definition
Adenosine>>>afferent arteriole>>>constriction>>>lower GFR
Term
where does glucose reabsorption occur?
Definition
PCT
Term
with the reabsorption of glucose in the pct, what is also reabsorbed?
Definition
sodium
Term
what is the process of glucose reabsorption fueled by?
Definition
sodium potassium pump
Term
what's the difference between regulation of absorption of glucose and phosphate?
Definition
glucose: will reabsorb as much glucose as possible (300-375 mg/100 ml)
phosphate:regulates it. can cause levels to go up and down
Term
as the filtrate moves from the pct to the descending limb, what is the concentration?
Definition
isotonic
Term
if a cell had a sodium-chloride-potassium pump in it, which part of tubule would it be?
Definition
thick ascending
Term
which cells does lasix act on?
Definition
the cells of the thick ascending limb (cells that have sodium-potassium-chloride pump)
Term
where does angiotensin I turn into angiotensin II?
Definition
lungs
Term
2 substances that can estimate GFR by their plasma clearance levels
Definition
inulin and creatinine
Term
what can plasma clearance of PAH be used to measure and why?
Definition
renal plasma flow bc all of it ends up in the filtrate (filtered, not reabsorbed, all of it secreted)
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