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Regulation of circulation
Chapter 42
22
Biology
Undergraduate 1
04/07/2014

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Term
systolic blood pressure
Definition
pressure in an artery when the ventricles are contracting
Term
diastolic blood pressure
Definition
pressure in the artery when the ventricles are relaxing
Term
Why is diastolic blood pressure not zero?
Definition
Peripheral resistance in the arteries, arterioles
Expand - systole
Snap back - diastole
Term
Why does the force of the heartbeat fall almost to zero in veins and venules?
Definition
Blood returns to the heart because of some pressure in veins from heartbeat
gravity
muscles near veins
Term
Measurement of blood pressure
Definition
Healthy adult: 120/70
Term
control mechanisms
Definition
constriction and dilation of arterioles; opening and shutting of precapillary sphincters
Term
action potential
Definition
an electrical signal in a nerve cell or a muscle cell is self-sustaining wave of membrane depolarization
results from the movement of ions across the plasma membrane
Term
cardiac cycle
Definition
an inherent activity of the heart because the heart has its own pacemaker but is modified by outside influences
Term
sinoatrial node (SA node)
Definition
the heart's natural pacemaker
can initiate atrial systole
The electrical signal initiated is an action potential just like in nerve cells
Term
Gap junctions
Definition
allow electrical current to pass from one myocardial cell to another
located in intercalated disks
Term
atrioventricular node (AV node)
Definition
passageway for contractional signals into ventricles
Term
How does slowing depolarization to threshold slow down heart rate?
Definition
Nerves releas acetylcholine (neurotransmitter) to the cells of the SA node, resulting tin the opening of K+ channels and the efflux of K+ from the cells. this lowers the resting potential of the cells.
Term
How can heart rate be accelerated by speeding depolarization to threshold?
Definition
Nerves release norepinephrine to the cells of the Sa node, which increases Ca2+ and Na+ influx
Nervous signals can also increase venous return of blood to the heart by venous constriction, and can strengthen ventricular contractions by allowing more Ca2+ into the ventricular cells.
Term
Assume a blood cell is in the right ventricle of the heart. Arrange the following list of structures in the order the blood cell would visit them in one trip around the body: right atrium, aorta, liver capillaries, pulmonary artery, venule (in liver), lung capillaries, inferior vena cava, left ventricle
Definition
Pulmonary artery, lung capillaries, left ventricle, aorta, liver capillaries, venule, inferior vena cava, right atrium
Term
What are two differences between veins and arteries?
Definition
Veins carry blood away from the heart and do not have valves
Term
When you check a person's pulse, you must touch an artery, not a vein. Why?
Definition
The blood flowing in an artery moves by the force of the heartbeat. By the time the blood reaches a vein, that force has dissipated, and the blood moves largely because of squeezing by the skeletal muscles and by gravity.
Term
What is special about the functioning of the cells of the SA node (the pacemaker), in contrast to the other cells of the heart?
Definition
The cells of the SA node initiate an electrical signal that causes the myocardial cells to contract
Term
What sort of gated ion channel (voltage-gated, mechanically-gated, or ligand-gated) would you expect to find in the SA node?
Definition
Since the SA node initiates an electrical signal, you would expect to find voltage-gated channels
Term
Why must the signal from the SA node be delayed at the AV node before it is passed to the ventricles?
Definition
The signal from the SA node, being an electrical signal, moves very fast; the delay at the AV node gives time for the ventricles to fill with blood before the signal for ventricular contraction is passed along
Term
How does the size of the conducting cells in the AV node contribute to the slowing of this signal?
Definition
The cells have a narrow diameter. The speed of conduction of an action potential (electrical signal) decreases with decreasing diameter of the conducting cell.
Term
What are two ways arterioles contribute to the regulation of circulation?
Definition
Arterioles can contract and dilate, thus restricting or increasing the blood supply to a capillary bed.
Arterioles have precapillary sphincters that can open and close, according to the tissue's need for oxygen.
Term
Why is diastolic blood pressure not equal to zero?
Definition
During systole, arteries do not empty completely; the arterioles receiving the blood will offer resistance to blood flow, a phenomenon called peripheral resistance. This resistance maintains some positive pressure in the arteries even during diastole.
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