Term
| What is the scientific name of MArijuana? |
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Definition
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Term
| What were the historical uses of Marijuana? |
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Definition
-Psychoactive intoxicant
-Hemp fiber |
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Term
| What is the principle psychoactive contituent of marijuana? |
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Definition
-Dilta-9-tetrahydrocannabinol
-aka THC |
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Term
| When was the Medical Marijuana Tax introduced? |
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Definition
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Term
| When was marijuana removed from the pHarmacopeia? |
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Definition
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Term
| When was marijuana classified as a Schedule I Substance by the Controlled Substances Act? |
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Definition
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Term
| What are the Endocannabinoid receptors? |
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Definition
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Term
| Where are endocannabinoid receptors found? |
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Definition
| -everywhere there is fat: brain, digestive tract, muscle, adipose tissue |
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Term
| What are the medical uses of THC? |
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Definition
-stimulates appetitie and reduces nausea
-may decrease pain, inflammation, spasticity |
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Term
| What is Cannabidiol? What does it do? |
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Definition
-non-psychoactive: no THC
-reduce pain, inflammation, control epileptic seizures |
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Term
| How does THC affect the brain physiologically? |
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Definition
| -highly lipophilic and thus crosses the BBB very readily and activates cannabinoid receptors |
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Term
| How does marijuana alter brain function? |
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Definition
-Cerebellum: motor control
-Hippocampus: short term memory, learning
-Cerebral cortex: sensory perception |
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Term
| What are the psychoactive effects of illicit marijuana use?n Other effects? |
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Definition
-heightened mood
-euphoria
-relaxation
-CNS depression and derangement: visual hallucinations, sensory perception changes, psychic exultation |
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Term
| What are some of the unwanted side effects of illicit marijuana use? |
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Definition
-diarrhea
-hypothermia
-muscle incoordination
-mydriasis
-resp depression
-reduced short term memory
-dry mouth
-impaired motor skills
-anxiety
-paranoia
-red eyes |
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Term
| What are the common sources of marijuana for pets? THC content? |
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Definition
-dried and chopped leaves, seeds, stems
-THC: 0.4-20% |
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Term
| What are the common sources of hashish for pets? THC content? |
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Definition
-resin: tops of flowering plants and oil
-resin > 10% but oil >20% |
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Term
| What is the common source of medical marijuana in pets? |
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Definition
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Term
| Describe the timing of peak brain effect in pets due to marijuana ingestion. |
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Definition
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Term
| Describe the timing of marijuana effects in second hand exposure in pets. What are the clinical signs of chronic exposure? |
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Definition
-rapid effect, shorter duration
-CS: resp irritation, rhinopharyngitis, asthma, brinchitis, chronic bronchiolitis, possible emphysema |
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Term
| What is the minimum lethal dose of marijuana? |
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Definition
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Term
| What three factors is marijuana toxicity dependent on? |
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Definition
-degree of purity
-TCH conc
-route of exposure |
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Term
| Where is marijuana stored in the body? How is it excreted in pets? |
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Definition
-adipose tissue
-enterohepatic circ to feces |
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Term
| What is the typical onset of clinical signs in dogs with marijuana? What are the general signs? |
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Definition
-30-60 mins after ingestion
-99% neuro signs and 30% GI signs |
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Term
| What are the CNS signs of marijuana in dogs? GI signs? |
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Definition
-CNS: depression, ataxia, mydriasis, hypersensitivity to motion/sound, hyperesthesia
-GI signs: vomiting |
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Term
| In addition to CNS and GI signs, what other clinical signs can result from marijuana in dogs? |
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Definition
-Sinus tachycardia
-ptyalism
-tremor
-urinary incontinence
-comatose, obtunded |
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Term
| What are some of the differentials for marijuana in dogs? |
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Definition
-Amphetamine
-Nicotine
-Ivermectin
-CHocolate
-Ethylene glycol
-Antidepressants
-Opiods
-Amitraz
-Bromethalin
-Benzodiazepines
-Ethanol |
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Term
| Can we use human urine tests for marijuana detection in dogs? |
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Definition
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Term
| HOw do we treat marijuana toxicity in dogs? |
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Definition
-emesis
-activated charcoal
-supportive care
-possible Diazepem/Chlorpromazine to trat agitation |
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Term
| How do we treat severe marijuana intoxications? |
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Definition
-IV lipid therapy (draws toxin from interstitium)
-supportive care |
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Term
| How is synthetic marijuana sold? |
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Definition
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Term
| Is synthetic marijuana seen on drug tests? |
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Definition
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Term
| What is the MOA of Spice? |
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Definition
-CBR
-more powerful, unpredictable, and may contain heavy metal residues |
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Term
| What are the typical side effects of Spice? |
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Definition
-elevated mood
-relaxation
-altered perception
-extreme anxiety
-paranoia
-hallucinations |
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Term
| What are the more severe side effects of spice? |
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Definition
-tachycardia
-vomiting
-agitation
-confusion
-hallucinations
-inc BP
-myocarida ischeia
-heart attack |
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Term
| How do we treat spice toxicity? |
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Definition
-emetics
-activated charcoal
-sedatives
-IVF support |
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