Term
β1 receptors (Location, Function, Mechanism) |
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Definition
Location: Heart, Salivary glands, Adipose tissue, Kidney. Contraction, Increase Heart Rate, lipolysis, gluconeogenesis, renin secretion. Stimulation of adenylyl cyclase. ↑cAMP
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Term
α1 receptors (Location, Function, Mechanism) |
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Definition
Locations: Vascular SM, Sphincters of GI and Bladder. Radial muscle of iris. Splanchnic vessels. Constriction, SM contraction IP3, intracellular ↑[Ca++]
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Term
α2 receptors (Locations, Function, Mechanism) |
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Definition
Location: Wall of presynaptic/post ganglionic neuron of GI. Relaxation. Decreases NE release. Inhibition of adenylyl cyclase ↓cAMP
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Term
β2 receptors (Locations, Function, Mechanism) |
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Definition
Location: Vascular SM of Skeletal muscle. Wall of GI and Bladder. Bronchioles. Dilation, Smooth muscle relaxation stimulation of adenylyl cyclase ↑cAMP
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Term
Nicotinic receptors (Location, Function, Mechanism) |
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Definition
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Term
Muscarinic receptors (location, Function, Mechanism) |
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Definition
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Term
What organs are under only sympathetic control? |
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Definition
Skeletal mucle(also Somatic NS) Radial muscle of iris (dilates/opend pupil) Sweat glands Liver, Adipose tissue, Kidney
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Term
What organs are under only parasympathetic control? |
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Definition
Lacrimal gland(tear duct) Gastric acid and Pancreatic secretion Endothelium, releases EDRF
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Term
Decribe the filling and emptying of the bladder. |
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Definition
Filling is done by sympathetic: - β2 relaxes the Detruror muscle to allow stuff in. - α1 contracts the internal sphincter(Trigone) to stop things from leaving. -External sphincter(skeletal muscle) is voluntarily contracted. Emptying is done by the parasympathetic: - Muscurinic contract the Detruror muscleto stop filling. -A seperate Muscurinic relaxes the internal sphincter(Trigone) to allow drainage. -External sphincter voluntarily relaxed. |
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Term
What stimulates Autonomic activity by stimulating post ganglionic neurons? |
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Definition
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Term
What stops autonomic activity by blocking post ganglioninc neuron conduction? |
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Definition
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Term
What increases autonomic activity by inhibiting acetylcholinesterase at ganglia synapses? |
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Definition
DFP (nerve gas) Physostigmine (Eserine) Neostigmine (Prostigmin)
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Term
What increases autonomic activity by causing post ganglionic neurons to release norepinepherin? |
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Definition
Ephedrine Amphetamine Cocaine
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Term
What slows autonomic activity by interfering with norepinepherin storage at postganglionic neurons? |
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Definition
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Term
What blocks Muscurinic receptors and dilates the pupils? |
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Definition
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Term
What anti-hypertensive drug stimulates α2 receptors? |
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Definition
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Term
What drug stimulates α1 receptors and is used as a nasal spray? |
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Definition
Phenylephrine (Neo-Synephrine) |
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Term
What drugs block ALL α receptors? |
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Definition
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Term
What drug stimulates β receptors? |
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Definition
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Term
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Definition
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Term
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Definition
Blocks Muscurinic receptors anticholinergic blocks parasympathetic affects pre-surgery drug blocks salivation and respitory system secretions
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Term
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Definition
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Term
Tricyclic anitdepressants |
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Definition
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Definition
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Term
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Definition
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Term
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Definition
Blocks all Nicotinic receptors |
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