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Reading Notes 1
Sections 1.1-1.3, 1.5, 6.1, 17.1-17.6, 22.6
82
Microbiology
Undergraduate 2
01/30/2014

Additional Microbiology Flashcards

 


 

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Term
microbe
Definition
an organism or virus too small to be seen with the unaided human eye.
Term
virus
Definition
a non-cellular particle containing a genome that can replicated only inside a cell
Term
prokaryote
Definition
an organism whose cell or cells lack a nucleus: includes both bacteria and archaea.
Term
eukaryote
Definition
an organism whose cells contain a nucleus and is a member of the domain Eukarya.
Term
genome
Definition
the complex genetic content of an organism. The sequence of all the nucleotides in a haploid set of chromosomes.
Term
metagenome
Definition
the sum of genomes of a community of organisms.
Term
spontaneous generation
Definition
the theory, much debated in the 19th century, that under current Earth conditions life can arise spontaneously from nonliving matter.
Term
fermentation
Definition
the production of ATP via substrate-level phosphorylation, using organic compounds as both electron donors and electron acceptors.
Term
autoclave
Definition
device that uses pressurized steam to sterilize material by raising the temperature above the boiling point of water at standard pressure.
Term
germ theory of disease
Definition
the theory that many diseases are caused by microbes.
Term
chain of infection
Definition
the serial passage of a pathogenic organism from an infected individual to an uninfected individual, thus transmitting disease.
Term
pure culture
Definition
a culture containing only a single strain or species of microorganism. A large number of microorganisms all descended from a single individual.
Term
colony
Definition
a visible cluster of microbes on a plate, all derived from a single founding microbe.
Term
petri dish
Definition
a round dish with vertical walls covered by an inverted dish of slightly large diameter. The smaller dish can be filled with a substrate for growing microbes.
Term
Koch's postulates
Definition
Four criteria that should be met for a microbe to designated the causative agent of an infectious disease.
Term
agar
Definition
a polymer of galactose that is used as a gelling agent.
Term
immunity
Definition
resistance to a specific disease.
Term
vaccination
Definition
exposure of an individual to a weakened version of a microbe to provoke immunity and prevent development of disease upon reexposure.
Term
immunization
Definition
the stimulation of an immune response by deliberate inoculation with a weakened pathogen, in hopes of providing immunity to disease caused by the pathogen.
Term
immune system
Definition
an organism’s cellular defense system against pathogens.
Term
antiseptic
Definition
chemical that kills microbes.
Term
aseptic
Definition
free of microbes.
Term
antibiotic
Definition
a molecule that can kill or inhibit the growth of selected microorganisms.
Term
polyphyletic
Definition
having multiple evolutionary origins.
Term
monophyletic
Definition
diverging from a common ancestor.
Term
virus
Definition
a non-cellular particle containing a genome that can replicated only inside a cell.
Term
virion
Definition
a virus particle.
Term
capsid
Definition
the protein shell that surrounds a virion's nucleic acid.
Term
bacteriophage
Definition
a virus that infects bacteria.
Term
plaque
Definition
a cell-free zone on a lawn of bacterial cells caused by viral lysis.
Term
host range
Definition
the species that can be infected by a given pathogen.
Term
cloning vectors
Definition
a small genome that can carry specific genes for cloning.
Term
viriod
Definition
an infectious naked nucleic acid
Term
reading frames
Definition
the position in a nucleic acid sequences from which triplet codons encode amino acids.
Term
prion
Definition
an infectious agent that causes propagation of misfolded host proteins; usually consists of a defective version of the host protein.
Term
supernova
Definition
an exploding star that has used up most of the nuclei available for fusion reactions.
Term
biosphere
Definition
the region containing the sum total of all life on Earth.
Term
greenhouse effect
Definition
the trapping of solar radiation heat in the atmosphere by CO2.
Term
Hadean eon
Definition
the first eon of Earth’s existence from 4.5 to 3.8 gigayears before the present.
Term
Archaean eon
Definition
the second eon of Earth's existence. from 3.8 to 2.5 gigayears before the present. The earliest geological evidence for life dates to this eon.
Term
microfossils
Definition
a microscopic fossil in which calcium carbonate deposits have filled in the form of ancient microbial cells.
Term
isotope ratio
Definition
the ratio of amounts of two different isotopes of an element. May serve as a biosignature if the ratio between certain isotopes of a given element is altered by biological activity.
Term
banded ion formation (BIFs)
Definition
a geological formation consisting of layers of oxidized iron, which indicates formation under oxygen-rich conditions.
Term
abiotically
Definition
produced without living organisms; occurring in the absence of life
Term
RNA world
Definition
a model of early life in which RNA perfomed all the information and catalytic roles of today’s DNA and proteins.
Term
prebiotic soup
Definition
a model for the origin of life based on the abiotic formation of fundamental biomolecules and cell structures such as membranes out of a “soup” of nutrients present on early Earth.
Term
metabolist model
Definition
a model of early life in which the central components of intermediary metabolism arose from self-sustaining chemical reactions based on inorganic chemicals.
Term
ribozymes
Definition
an RNA capable of enzymatic reactions.
Term
panspermia
Definition
the hypothesis that life-forms originated elsewhere and “seeded” life on Earth.
Term
clades/monophyletic group
Definition
a group of organisms that includes an ancestral species and all of its descendents.
Term
reductive evolution
Definition
the loss of mutation of DNA encoding unselected traits.
Term
molecular clock
Definition
the use of DNA or RNA sequence information to measure the time of divergence among different species.
Term
small subunit rRNA (SSU rRNA)
Definition
in bacteria, 16S rRNA. A ribosomal RNA found in the small subunit of the ribosome. Its gene is often sequenced for phylogenetic comparisons.
Term
phylogenic tree
Definition
a diagram depicting estimates of the relative amounts of evolutionary divergence among different species.
Term
root of a tree
Definition
the earliest common ancestor of all members of a phylogenetic tree.
Term
horizontal gene transfer
Definition
the passage of genes from one cell into another mature cell.
Term
vertical gene transfer
Definition
gene transfer from parent to offspring through reproduction.
Term
genomic islands
Definition
a region of DNA sequence whose properties indicate that it has been transferred from another genome. Usually comprises a set of genes with shared function, such as pathogenicity or symbiosis support.
Term
pan-genome
Definition
all the genes possessed by all individual members of species.
Term
core genome
Definition
a set of genes shared by a group of related bacterial strains, showing stable inheritance.
Term
taxonomy
Definition
the description of distinct life-forms and their organization into different categories.
Term
classification
Definition
the recognition of different forms of life and their placement into different categories.
Term
nomenclature
Definition
the naming of different taxonomic groups of organisms.
Term
identification
Definition
the recognition of the class of a microbe isolated in pure culture.
Term
species
Definition
a single, specific type of organisms designated by a genus and species name.
Term
genus name
Definition
the Latin name assigned to the taxonomic rank consisting of closely related species.
Term
species name
Definition
the scientific name of a specific type of organism; presented following the genus names as in Escherichia (genus) coli (species).
Term
isolate
Definition
a microbe that has been obtained from a specific location and grown in pure culture.
Term
candidate species
Definition
a newly described microbial isolate that may become accepted as an official species.
Term
metagenomics
Definition
the study of community genomes, or metagenomes.
Term
dichotomous key
Definition
a tool for identifying organisms, in which a series of yes/no decisions successively narrows down the possible categories of species.
Term
probabilistic indicator
Definition
a means of quickly identifying microbes in the clinical setting, based on a battery of biochemical tests performed simultaneously on an isolated strain.
Term
symbiosis
Definition
the intimate association of two unrelated species.
Term
mutualism
Definition
a symbiotic relationship in which both partners benefit.
Term
parasitism
Definition
a symbiotic relationship un which one member benefits and the other is harmed.
Term
coevolution
Definition
the evolution of two species in response to one another.
Term
endosymbiosis
Definition
an intimate association between different species in which one partner population grows within the body of another organism.
Term
endosymbiont
Definition
an organism that lives as a symbiont inside another organism.
Term
symbiogenesis
Definition
an evolutionary process by which two or more species become intimately associated.
Term
biosignatures
Definition
a chemical indicator of life.
Term
terraforming
Definition
the idea transforming the environment of another planted to make it suitable for life from Earth.
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