Shared Flashcard Set

Details

Rau's Resp. Care Pharmacology - Ch. 11,12,13
Rau's Resp. Care Pharmacology - Ch. 11,12,13
104
Pharmacology
Undergraduate 1
10/13/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
What are Beclomethasone's side effects?
Definition
Fungal infection in the mouth. Minimal systemic effects
Term
Beclomethasone's trade names
Definition

Vanceril,

Beclovent

Term
Beclomethasone's classification
Definition
Steroidal Antiinflammatory
Term
Beclomethasone dosage
Definition
MDI .252 mg (0.084 mg/actuation)
Term
Beclomethasone's instruction
Definition
Rinse mouth and/or use spacer
Term
Beclomthasone dipropionate's classification
Definition
Steroidal Antiinflammatory
Term
Beclomthasone dipropionate's dosage
Definition
MDI @ 40 or 80 mcg/puff
Term
Beclomthasone dipropionate's instruction
Definition
Rinse mouth and/or use spacer
Term
Beclomthasone dipropionate's side effects
Definition
Fungal infections in mouth. Minimal systemic effects
Term
Beclomthasone dipropionate's trade name
Definition
QVAR
Term
Triamcinolone’s side effects?
Definition
Fungal infection in mouth. Minimal systemic effects
Term
Triamcinolone's classification?
Definition
Steroidal Antiinflammatory
Term
Triamcinolone dosage
Definition
MDI 200 mcg (42 mcg/actuation)
Term
Triamcinolone's instruction?
Definition
Rinse mouth and/or use spacer
Term
Triamcinolone's trade name
Definition
Azmacort
Term
Flunisolide's instructions
Definition
Rinse mouth and/or use spacer
Term
Flunisolide's side effects
Definition
Fungal infections in mouth. Minimal systemic effects
Term
Flunisolide's trade name
Definition

Aerobid

AerobidM

Term
Flunisolide's classification
Definition
Steroidal Antiinflammatory
Term
Flunisolide's dosage?
Definition
MDI 500 mcg (250 mcg/actuation)
Term
Fluticasone propionate's instructions?
Definition
Rinse mouth and/or use spacer
Term
Fluticasone propionate's receptor sites?
Definition
Beta 1, Beta 2
Term
Fluticasone propionate's side effects?
Definition
Increased HR, tremors, nervousness, thrush
Term
Fluticasone propionate's side effects?
Definition
Fungal infections in the mouth. Minimal systemic effects
Term
Fluticasone propionate's classification?
Definition
Combo longlasting adrenergic bronchodilator and steroid
Term
Fluticasone propionate's classification?
Definition
Steroidal Antiinflammatory
Term
Fluticasone propionate's dosage?
Definition
MDI/DPI BID (2x/day)
125/25 mcg or 250/25 mcg
Term
Fluticasone propionate's generic names
Definition
Salmeterol xinafoate
Term
Fluticasone propionate's trade name?
Definition
Advair HFA
Term
Budesonide's Receptor sites?
Definition
Beta 1, Beta 2
Term
Budesonide's side effects?
Definition
Increased HR, tremor, nervousness, thrush
Term
Budesonide's side effects?
Definition
Fungal infections in mouth
Term
What is Budesonide's classification?
Definition
Combination longacting adrenergic bronchodilator and steroid
Term
What is Budesonide's dosage?
Definition
MDI 80/4.5 ug and 160/4.5 ug Budesonide and Formoterol 2 puffs BID (MDI = Metered Dose Inhaler)
Term
What is Budesonide's dosage?
Definition
.25 mg/ml or 0.5 mg/ml
Term
What is Budesonide's other generic name?
Definition
Formoterol fumarate dihydrate
Term
What is Budesonide's trade name?
Definition
Symbicort
Term
What is Budesonide's trade name?
Definition
Pulmicort Respules
Term
What are Fluticasone propionate's instructions?
Definition
Rinse mouth and/or use spacer
Term
What are Fluticasone propionate's receptor sites?
Definition
Beta 1, Beta 2 (Hint: Beta 1 (one heart), Beta 2 (two lungs)) Have patient rinse mouth
Term
What are Fluticasone propionate's side effects?
Definition
Increased HR, tremors, nervousness, thrush
Term
What is Fluticasone propionate's classification?
Definition
Combination longlasting adrenergic bronchodilator and steroid
Term
What is Fluticasone propionate's classification?
Definition
Steroidal Antiinflammatory
Term
What is Fluticasone propionate's dosage?
Definition
MDI/DPI BID (2x/day)
2 dosage strengths 125/25 mcg and 250/25 mcg
Term
What is Fluticasone propionate's other generic name?
Definition
Salmeterol xinafoate
Term
What is Fluticasone propionate's trade name?
Definition
Advair HFA
Term
What are Cromolyn sodium's Side effects?
Definition
Cough and bronchospasm in powder form only
Term
What is Cromolyn sodium's 1st trade name?
Definition
Intal
Term
What is Cromolyn sodium's 2nd trade name?
Definition
Aarane
Term
What is Cromolyn sodium's classification?
Definition
NonSteroidal AntiInflammatory (NSAID)
Term
What is Cromolyn sodium's Dosage?
Definition
20 mg MDI 1600 mcg (800 mcg/actuation)(MDI = Metered Dose Inhaler)
Term
What is Cromolyn sodium's Instructions?
Definition
2 puffs 1015 minutes (not >60) before exercise; cold, dry air or environmental agents for acute
Term
What is Nedocromil sodium's classification?
Definition
Non Steroidal Anti Inflammatory (NSAID)
Term
What is Nedocromil sodium's dosage?
Definition
MDI 3.5 mg QID (1.75 mg/actuation)(MDI = Metered Dose Inhaler)(QID = Four times a day)
Term
What is Nedocromil sodium's instruction?
Definition
Must be taken regularly to achieve benefit
Term
What is Nedocromil sodium's side effect?
Definition
Unpleasant taste
Term
What is Nedocromil sodium's trade name?
Definition
Tilade
Term
What are Pentamindine’s side effects?
Definition
Cough, Bronchospasm
Term
What is Pentamindine's classification?
Definition
Antibiotic
Term
What is Pentamindine's dosage?
Definition
600 mg once/day using the Respiguard Nebulizer. 
with 6 ml of sterile water. Run at 8 LPM
Term
What is Pentamindine's trade name?
Definition
NebuPent
Term
What is Tobramycin's classification?
Definition
Antibiotic
Term
What is Tobramycin's dosage?
Definition
80 mg
Term
What is Tobramycin's instruction?
Definition
Do not mix with other meds!
Term
What is Tobramycin's trade name?
Definition
Nebcin
Term
inflammation is mediated by
Definition

eosinophils

mast cells

Term
Side Effects Seen With Systemic Administration of Corticosteroids
Definition
• Hypothalamic–pituitary–adrenal suppression • Immunosuppression • Psychiatric reactions • Cataract formation • Myopathy of skeletal muscle • Osteoporosis • Peptic ulcer • Fluid retention • Hypertension • Increased white blood cell count • Dermatological changes • Growth restriction • Increased glucose levels
Term
Adrenal insufficiency*
Definition
Oropharyngeal fungal infections
Term
Extrapulmonary allergy*
Definition
Dysphonia
Term
Acute asthma*
Definition
Cough, bronchoconstriction
Term
HPA suppression (minimal, dose dependent)
Definition
Incorrect use of MDI (inadequate dose)
Term
eosinophils predominate in _______
neutrophils are mostly seen in ____
Definition
asthma
COPD
Patient with stable COPD
should not be given systemic corticosteroids
Term
Three subgroups of agents are included in the nonsteroidal antiasthma group:
Definition
cromolyn-like drugs (mast cell stabilizers)
antileukotrienes (anti-LTs)
monoclonal antibodies.
Term
The general indication for clinical use of nonsteroidal antiasthma agents described in this chapter is ....
Definition
prophylactic management (control) of mild persistent asthma
Term
All of the nonsteroidal antiasthma drugs described in this chapter are _____, not ______, and are used in asthma requiring ________________
Definition
controllers
relievers
antiinflammatory drug therapy
Term
A sensitized mast cell fails to degranulate after challenge when ________
Definition
pretreated with cromolyn sodium
Term
Pentamidine is used for
Definition
(PCP) Pneumocystis pneumonia
Term
Inhaled tobramycin used for management of ______ infections in patients with cystic fibrosis.
Definition
Pseudomonas aeruginosa infections in patients with cystic fibrosis. Zanamivir is an inhaled antiviral agent used to treat influenza.
Term
indication for Aerosolized Pentamidine
Definition
Pentamidine by inhalation is indicated for the prevention of PCP in high-risk HIV–infected patients who have a history of one or more episodes of PCP or a peripheral CD4+ (T4 helper cell) lymphocyte count of 200/mm3 or less.
Term
Indication for Aerosolized Ribavirin
Definition
in infant respiratory syncytial virus (RSV).
Term
aerosolized pentamidine must be given via
Definition
Respirgard II nebulizer.
Term
mode of action of pentamidine
Definition
not known
Term
Side Effects With Parenteral Pentamidine
Definition
Pain, swelling, and abscess formation at the site of injection, with intramuscular administration
Term
Side Effects With Aerosol Administration. Side effects with aerosol administration can be differentiated into local airway effects and systemic effects. Local airway effects with aerosol administration have included the following:
Definition
Cough and bronchial irritation in 36% of patients in one study3
Shortness of breath
Bad taste (bitter or burning) of the aerosol impacting in the oropharynx
Bronchospasm and wheezing in 11% of patients3
Spontaneous pneumothoraces13
In addition, the following systemic reactions have occurred with aerosolized pentamidine:
Conjunctivitis
Rash
Neutropenia
Pancreatitis14
Renal insufficiency
Dysglycemia (hypoglycemia and diabetes)
Digital necrosis in both feet15
Appearance of extrapulmonary P. carinii infection
Term
Use of a β-adrenergic bronchodilator before inhaling aerosolized pentamidine can
Definition
reduce or prevent local airway reaction, including reduction of coughing or wheezing.
Term
Ribavirin (Virazole) is classified as an antiviral drug; it is active against RSV, influenza viruses, and herpes simplex virus.
Definition
virostatic
Term
virostatic - stops it from reproducing
Definition
virostatic - stops it from reproducing
Term
Infection with RSV in children results in either bronchiolitis or pneumonia.
Definition
Infection with RSV in children results in either bronchiolitis or pneumonia.
Term
Respiratory syncytial virus (RSV) can cause bronchiolitis and pneumonia.
Definition
Respiratory syncytial virus (RSV) can cause bronchiolitis and pneumonia.
Term
Ribavirin is given as a 20-mg/ml solution, which is administered by nebulizer (SPAG-2) for 12 to 18 hours per day, for a minimum of 3 days and not more than 7 days.
Definition
Ribavirin is given as a 20-mg/ml solution, which is administered by nebulizer (SPAG-2) for 12 to 18 hours per day, for a minimum of 3 days and not more than 7 days.
Term
Tobramycin
Definition
antibiotics
Term
The use of TOBI is intended to manage chronic infection with P. aeruginosa in cystic fibrosis, as follows:
Definition
Treat or prevent early colonization with P. aeruginosa
Term
TOBI usage
Definition
for those 6 years or older
300 mg 2 x day
12 hours apart (min. 6 hours apart)
28 days on/28 off
Term
Patients should be instructed not to mix dornase alfa or any other drug with tobramycin in the nebulizer.
Definition
after other therapies
Term
Definition
Ototoxicity (auditory and vestibular)
Term
Definition
Nephrotoxicity
Term
Definition
Neuromuscular blockade
Term
Definition
Hypomagnesemia
Term
Definition
Cross-allergenicity
Term
Definition
Fetal harm (deafness)
Term
Definition
Voice alteration
Term
Definition
Tinnitus
Term
Definition
Nonsignificant increase in bacterial resistance
Term
Zanamivir (Relenza) uses
Definition
Zanamivir (Relenza) is antiviral for treatment of uncomplicated influenza illness (as DPI) in adults and children over 5, during first 2 days of infection.
Supporting users have an ad free experience!