Shared Flashcard Set

Details

Rapid Review
USMLE studying
476
Medical
Graduate
05/16/2014

Additional Medical Flashcards

 


 

Cards

Term

Abdominal pain

Ascites

Hepatomegaly

Definition

Budd-Chiari Syndrome

(posthepatic venous thrombosis)

Term
Achilles tendon xanthoma
Definition

Familial Hypercholesterolemia

(decreased LDL receptor signaling)

Term

Adrenal hemorrhage

Hypotension

DIC

Definition

Waterhouse-Friderichsen Syndrome

(Meningococcemia)

Term
Anterior "drawer" sign
Definition
Anterior Cruciate ligament injury
Term

Arachnodactyly

Lens dislocation

Aortic dissection

Hyperflexible joints

Definition

Marfan Syndrome

(Fibrillin defect)

Term
Athlete with polycythemia
Definition
Secondary to erythropoietin injection
Term

Back pain

Fever

Night sweats

Weight loss

Definition

Pott Disease

(Vertebral TB)

Term

Bilateral hilar adenopathy

Uveitis

Definition

Sarcoidosis

(Noncaseating granulomas)

Term
Blue sclera
Definition

Osteogenesis Imperfecta

(Type I collagen defect)

Term
Bluish line on gingiva
Definition

Burton Line

(Lead poisoning)

Term

Bone pain

Bone enlargement

Arthritis

Definition

Paget Disease of Bone

(increased osteoblastic and osteoclastic activity)

Term

Bounding pulses

Diastolic heart murmur

Head bobbing

Definition
Aortic Regurgitation
Term

"Butterfly" facial rash

Raynaud phenomenon

Young female

Definition
Systemic Lupus Erythematosus (SLE)
Term

Cafe-au-lait spots

Lisch nodules (iris hamartoma)

Definition

Neurofibromatosis Type I

(pheochromocytoma, optic gliomas)

Term

Cafe-au-lait spots

Polyostotic fibrous dysplasia

Precocious puberty

Multiple endocrine abnormalities

Definition

McCune-Albright Syndrome

(mosaic G-protein signaling mutation)

Term
Calf pseudohypertrophy
Definition

Muscular Dystrophy [usually Duchenne]

(X-linked recessive deletion of dystrophin gene)

Term
"Cherry-red spots" on macula
Definition

Tay-Sachs (ganglioside accumulation)

Niemann-Pick (sphingomyelin accumulation)

Central Retinal artery occlusion

Term
Chest pain on exertion
Definition

Angina

(Stable: with moderate exertion

Unstable: with minimal exertion)

Term

Chest pain

Pericardial effusion/friction rub

Persistent fever following MI

Definition

Dressler Syndrome

(autoimmune-mediated post-MI fibrinous pericarditis

1-12 weeks after acute episode)

Term
Child uses arms to stand up from squat
Definition

Gowers sign

(Duchenne Muscular Dystrophy)

Term
Child with fever later develops red rash on face that spreads to body
Definition

"Slapped cheeks" - Erythema Infectiosum/Fifth Disease

(Parvovirus B19)

Term

Chorea

Dementia

Caudate degeneration

Definition

Huntington Disease

(autosomal dominant CAG repeat expansion)

Term

Chronic exercise intolerance

Myalgia

Fatigue

Painful cramps

Myoglobinuria

Definition

McArdle Disease

(muscle glycogen phosphorylase deficiency)

Term

Conjugate lateral gaze palsy

Horizontal diplopia

Definition

Internuclear Ophthalmoplegia

(damage to MLF)

 

Bilateral = Multiple Sclerosis

Unilateral = Stroke

Term
Continuous "machine-like" heart murmur
Definition

PDA

(Close with Indomethacin

Open/Maintain with Misoprostal [PGE])

Term
Cutaneous/dermal edema due to connective tissue deposition
Definition

Myxedema

(Cause:

Hypothyroidism

Graves disease [pretibial])

Term
Dark purple skin/mouth nodules in a patient with AIDS
Definition

Kaposi Sarcoma

(associated with HHV-8)

Term

Deep, labored breathing

Hyperventilation

Definition

Kussmaul Respirations

(Diabetic Ketoacidosis)

Term

Dermatitis

Dementia

Diarrhea

Definition

Pellagra

(Niacin [vitamin B3] deficiency)

Term

Dilated cardiomyopathy

Edema

Alcoholism or Malnutrition

Definition

Wet Beriberi

(Thiamine [vitamin B1] deficiency)

Term
Dog or cat bite > infection
Definition

Pasteurella multocida

(cellulitis at inoculation site)

Term

Dry eyes

Dry mouth

Arthritis

Definition

Sjogren Syndrome

(autoimmune destruction of exocrine glands)

Term

Dysphagia (esophageal webs)

Glossitis

Iron deficiency anemia

Definition

Plummer-Vinson Syndrome

(may progress to esophageal squamous cell carcinoma)

Term

Elastic skin

Hypermobility of joints

Definition

Ehlers-Danlos Syndrome

(Type III collagen defect)

Term
Enlarged, hard left supraclavicular node
Definition

Virchow node

(Abdominal metastasis)

Term

Erythroderma

Lymphadenopathy

Hepatosplenomegaly

Atypical T-cells

Definition

Mycosis Fungoides (cutaneous T-cell lymphoma)

Sezary Syndrome (mycosis fungoides + malignant T-cells in blood)

Term
Facial muscle spasm upon tapping
Definition

Chvostek sign

(Hypocalcemia)

Term

Fat

Female

Forty

Fertile

Definition

Cholelithiasis

(gallstones)

Term

Fever

Chills

Headache

Myalgia

Following antibiotic treatment for Syphilis

Definition

Jarisch-Herxheimer Reaction

(rapid lysis of spirochetes results in toxin release)

Term

Fever

Cough

Conjunctivitis

Coryza

Diffuse rash

Definition
Measles
Term

Fever

Night sweats

Weight loss

Definition
B-symptoms (staging) of lymphoma
Term
Fibrous plaques in soft tissue of penis
Definition

Peyronie Disease

(connective tissue disorder)

Term

Gout

Intellectual disability

Self-mutilating behavior

Boy

Definition

Lesch-Nyhan Syndrome

(HGPRT deficiency, x-linked recessive)

Term
Green-yellow rings around peripheral cornea
Definition

Kayser-Fleischer rings

(copper accumulation from Wilson disease)

Term

Hamartomatous GI polyps

Hyperpigmentation of mouth/feet/hands

Definition

Peutz-Jeghers Syndrome

(inherited, benign polyposis > bowel obstruction

increased cancer risk [mostly GI])

Term

Hepatosplenomegaly

Osteoporosis

Neurologic symptoms

Definition

Gaucher Disease

(glucocerebrosidase deficiency)

Term

Hereditary nephritis

Sensorineural hearing loss

Cataracts

Definition

Alport Syndrome

(mutation in collagen IV)

Term

Hyperphagia

Hypersexuality

Hyperorality

Hyperdocility

Definition

Kluver-Bucy Syndrome

(bilateral amygdala lesion)

Term

Hyperreflexia

Hypertonia

Babinski sign present

Definition
UMN damage
Term

Hyporeflexia

Hypotonia

Atrophy

Fasciculations

Definition
LMN damage
Term

Hypoxemia

Polycythemia

Hypercapnia

Definition

"Blue Bloater" - Chronic Bronchitis

(hyperplasia of mucous cells)

Term
Indurated, ulcerated genital lesion
Definition

Nonpainful = Chancre (Primary Syphilis, Treponema pallidum)

 

Painful with exudate = Chancroid (Haemophilus ducreyi)

Term

Infant with cleft lip/palate

Microcephaly or Holoprosencephaly

Polydactyly

Cutis aplasia

Definition

Patau Syndrome

(Trisomy 13)

Term

Infant with failure to thrive

Hepatosplenomegaly

Neurodegeneration

Definition

Niemann-Pick Disease

(genetic sphingomyelinase deficiency)

Term

Infant with hypoglycemia

Failure to thrive

Hepatomegaly

Definition

Cori Disease (debranching enzyme deficiency)

 

Von Gierke Disease (glucose-6-phosphatase deficiency [more severe!])

Term

Infant with microcephaly

Rocker-bottom feet

Clenched hands

Structural heart defect

Definition

Edwards Syndrome

(Trisomy 18)

Term

Jaundice

Palpable distended non-tender gallbladder

Definition

Courvoisier Sign

(distal obstruction of biliary tree)

Term
Large rash with bull's-eye appearance
Definition

Erythema Chronicum Migrans from Ixodes tick bite

(Lyme Disease: Borrelia burgdorferi)

Term
Lucid interval after traumatic brain injury
Definition

Epidural Hematoma

(Middle Meningeal artery rupture)

Term

Male child

Recurrent infections

No mature B-cells

Definition

Bruton Disease

(X-linked agammaglobulinemia)

Term

Mucosal bleeding

Prolonged bleeding time

Definition

Glanzmann Thrombasthenia

(defect in platelet aggregation due to lack of GpIIb/IIIa)

Term

Muffled heart sounds

Distended neck veins

Hypotension

Definition
Beck Triad of Cardiac Tamponade
Term

Multiple colon polyps

Osteomas/soft tissue tumors

Impacted/supernumerary teeth

Definition

Gardner Syndrome

(subtype of FAP)

Term

Myopathy (infantile hypertrophic cardiomyopathy)

Exercise intolerance

Definition

Pompe Disease

(lysosomal a-1,4-glucosidase deficiency)

Term
Neonate with arm paralysis following difficult birth
Definition

Erb-Duchenne Palsy

(superior trunk [C5-C6] brachial plexus injury

"Waiter's tip")

Term

No lactation postpartum

Absent menstruation

Cold intolerance

Definition

Sheehan Syndrome

(pituitary infarction)

Term

Nystagmus

Intention tremor

Scanning speech

Bilateral internuclear ophthalmoplegia

Definition

Multiple Sclerosis

(autoimmune destruction of oligodendrocytes)

Term
Oscillating slow/fast breathing
Definition

Cheyne-Stokes respirations

(central apnea in CHF or increased intracranial pressure)

Term

Painful blue fingers/toes

Hemolytic anemia

Definition

Colg agglutinin disease

(autoimmune hemolytic anemia caused by Mycoplasma pneumoniae, infectious Mononucleosis)

Term
Painful, pale, cold fingers/toes
Definition

Raynaud Phenomenon

(vasospasm in extremities)

Term
Painful, raised red lesions on pad of fingers/toes
Definition

Osler nodes

 

(Causes:

Infective endocarditis

Immune complex deposition)

Term
Painless erythematous lesions on palms and soles
Definition

Janeway Lesions

(Causes:

Infective endocarditis

Septic emboli/microabscesses)

Term
Painless jaundice
Definition
Cancer of pancreatic head obstructive bile duct
Term

Palpable purpura on buttocks/legs

Joint pain

Abdominal pain (child)

Hematuria

Definition

Henoch-Schonlein Purpura

(IgA vasculitis affecting skin and kidneys)

Term
Pancreatic, Pituitary, Parathyroid tumors
Definition

MEN 1

(autosomal dominant)

Term

Periorbital and/or peripheral edema

Proteinuria

Hypoalbuminemia

Hypercholesterolemia

Definition
Nephrotic Syndrome
Term

Pink complexion

Dyspnea

Hyperventilation

Definition

"Pink Puffer" - Emphysema

(Centriacinar [smoking], Panacinar [a1-antitrypsin deficiency])

Term

Polyuria

Renal tubular acidosis type II

Growth failure

Electrolyte imbalances

Hypophosphatemic rickets

Definition

Fanconi Syndrome

(Proximal tubular reabsorption defect)

Term

Pruritic, purple, polygonal planar papules and plaques

(6 P's)

Definition
Lichen Planus
Term

Ptosis

Miosis

Anhidrosis

Definition

Horner Syndrome

(sympathetic chain lesion)

Term
Pupil accomodates but doesn't react
Definition

Argyll Robertson pupil

(Neurosyphilis)

Term
Rapidly progressive leg weakness that ascends following GI/upper respiratory infection
Definition

Guillain-Barre Syndrome

(acute autoimmune inflammatory demyelinating polyneuropathy that attach Schwann cells)

Term
Rash on palms and soles
Definition

Coxsackie A

Secondary Syphilis

Rocky Mountain Spotted Fever

Term

Recurrent colds

Unusual eczema

High serum IgE

Definition

Hyper-IgE Syndrome

 

(Job Syndrome - neutrophil chemotaxis abnormality)

Term
Red "currant jelly" sputum in alcoholic or diabetic patients
Definition
Klebsiella pneumoniae
Term
Red "currant jelly" stools
Definition

Acute mesenteric ischemia (adults)

 

Intussusception (infants)

Term
Red, itchy, swollen rash of nipples/areola
Definition

Paget disease of the breast

(signs of underlying neoplasm)

Term

Red urine in morning

Fragile RBCs

Definition
Paroxysmal Nocturnal Hemoglobinuria
Term

Renal cell carcinoma (bilateral)

Hemangioblastomas

Angiomatosis

Pheochromocytoma

Definition

von Hippel-Lindae disease

(dominant tumor suppressor gene mutation)

Term

Resting tremor

Rigidity

Akinesia

Postural instability

Definition

Parkinson disease

(nigrostriatal dopamine depletion)

Term
Retinal hemorrhages with pale centers
Definition

Roth spots

(bacterial endocarditis)

Term
Severe jaundice in neonate
Definition

Crigler-Najjar syndrome

(congenital unconjugated hyperbilirubinemia)

Term
Severe RLQ pain with palpation of LLQ
Definition

Rovsing sign

(acute appendicitis)

Term
Severe RLQ pain with rebound tenderness
Definition

McBurney Sign

(acute appendicitis)

Term

Short stature

Increased incidence of tumors/leukemia

Aplastic anemia

Definition

Fanconi Anemia

(genetic loss of DNA crosslink repair

often progresses to AML)

Term
Single palmar crease
Definition
Down Syndrome
Term

Situs inversus

Chronic sinusitis

Bronchiectasis

Infertility

Definition

Kartagener Syndrome

(dynein arm defect affecting cilia)

Term

Skin hyperpigmentation

Hypotension

Fatigue

Definition

Addison Disease

(primary adrenocortical insufficiency > increased ACTh and a-mSH production)

Term
Slow, progressive muscle weakness in boys
Definition

Becker Muscular Dystrophy

(X-linked missense mutation in dystrophin

Less severe than Duchenne)

Term
Small, irregular red spots on buccal/lingual mucosa with blue-white centers
Definition

Koplik Spots

 

(Causes:

Measles

Rubeola virus)

Term
Smooth, flat, moist, painless white lesions on genital
Definition

Condylomata lata

(Secondary Syphilis)

Term
Splinter hemorrhages in fingernails
Definition
Bacterial Endocarditis
Term
"Strawberry tongue"
Definition

Scarlet Fever

Kawasaki Disease

Toxic Shock Syndrome

Term

Streak ovaries

Congenital heart disease

Horseshoe kidney

Cystic hygroma at birth

Short stature

Webbed beck

Lymphedema

Definition

Turner Syndrome

(45,XO)

Term

Sudden swollen/painful big toe joint

Tophi

Definition

Gout/Podagra

(hyperuricemia)

Term

Swollen gums

Mucosal bleeding

Poor wound healing

Patechiae

Definition

Scurvy

(Vitamin C deficiency > can't hydroxylate proline/lysine for collagen synthesis)

Term
Swollen, hard, painful finger joints
Definition

Osteoarthritis

 

Bouchard nodes = osteophytes on PIP

Heberden nodes = osteophytes on DIP

Term
Systolic ejection murmur (crescendo-decrescendo)
Definition
Aortic Valve Stenosis
Term

Thyroid and parathyroid tumors

Pheochromocytoma

Definition

MEN 2A

(autosomal dominant ret mutation)

Term

Thyroid tumors

Pheochromocytoma

Ganglioneuromatosis

Definition

MEN 2B

(autosomal dominant ret mutation)

Term
Toe extension/fanning upon plantar scrape
Definition

Babinski sign

(UMN lesion)

Term
Unilateral facial drooping involving forehead
Definition

Facial nerve

(LMN CN 7 palsy)

Term

Urethritis

Conjunctivitis

Arthritis

Male

Definition
Reactive arthritis associated with HLA-B27
Term
Vascular birthmark (port-wine stain)
Definition

Hemangioma

(benign, but associated with Sturge-Weber syndrome)

Term
Vomiting blood following gastroesophageal lacerations
Definition

Mallory-Weiss Syndrome

(alcoholic and bulimic patients)

Term

Weight loss

Diarrhea

Arthritis

Fever

Adenopathy

Definition

Whipple Disease

(Tropheryma whipplei)

Term
"Worst headache of my life"
Definition
Subarachnoid hemorrhage
Term

Anticentromere antibodies

 

Definition
Scleroderma (CREST)
Term
Antidesmoglein (epithelial) antibodies
Definition

Pemphigus Vulgaris

(blistering)

Term
Anti-glomerular basement membrane antibodies
Definition

Goodpasture Syndrome

(glomerulonephritis and hemoptysis)

Term
Antihistone antibodies
Definition

Drug-induced SLE

 

(Hydralazine

INH

Phenytoin

Procainamide)

Term
Anti-IgG antibodies
Definition

Rheumatoid Arthritis

 

(systemic inflammation, joint pannus, boutonniere deformity)

Term
Antimitochondrial antibodies (AMAs)
Definition

Primary Biliary Cirrhosis

 

(female, cholestasis, portal HTN)

Term
Antineutrophil Cytoplasmic antibodies (ANCAs)
Definition

Microscopic Polyangiitis

Churg-Strauss Syndrome

(MPO-ANCA/p-ANCA)

 

Granulomatosis with Polyangiitis

(Wegener: PR3-ANCA/c-ANCA)

Term

Antinuclear antibodies

(ANAs: anti-Smith and anti-dsDNA)

Definition

SLE

(Type III hypersensitivity)

Term
Antiplatelet antibodies
Definition
Idiopathic Thrombocytopenic Purpura
Term
Anti-topoisomerase antibodies
Definition
Diffuse Systemic Scleroderma
Term

Anti-transglutaminase

Anti-gliadin

Anti-endomysial

Definition

Celiac disease

 

(diarrhea, distention, weight loss)

Term
"Apple core" lesion on abdominal x-ray
Definition

Colorectal cancer

(usually left-sided)

Term
Azurophilic peroxidase positive granular inclusions in granulocytes and myeloblasts
Definition

Auer Rods

(AML, especially promyelocytic [M3] type)

Term
Bacitracin response
Definition

Sensitive = Streptococcus pyogenes (group A)

Resistant = Streptococcus agalactiae (group B)

Term
"Bamboo spine" on x-ray
Definition

Anklylosing Spondylitis

(chronic inflammatory arthritis

HLA-B27)

Term
Basophilic nuclear remnants in RBCs
Definition

Howell-Jolly bodies

 

(due to splenectomy or nonfunctional spleen)

Term
Basophilic stippling of RBCs
Definition

Lead poisoning

Sideroblastic anemia

Term
Bloody tap on LP
Definition
Subarachnoid Hemorrhage
Term
"Boot-shaped" heart on x-ray
Definition

Tetralogy of Fallot

RVH

Term
Branching gram-positive rods with sulfur granules
Definition
Actinomyces israelii
Term
Bronchogenic apical lung tumor on imaging
Definition

Pancoast Tumor

(can compress sympathetic ganglion > Horner Syndrome)

Term
"Brown" tumor of bone
Definition

Hyperparathyroidism

 

Osteitis Fibrosa Cystica

(deposited hemosiderin from hemorrhage > brown color)

Term
Cardiomegaly with apical atrophy
Definition

Chagas disease

(Trypanosoma cruzi)

Term
Cellular crescents on Bowman capsule
Definition
Rapidly progressive crescentic glomerulonephritis
Term
"Chocolate cyst" of ovary
Definition

Endometriosis

(frequently involves both ovaries)

Term
Circular grouping of dark tumor cells surrounding pale neutrophils
Definition

Homer-Wrist rosettes

 

(Neuroblastoma

Medulloblastoma

Retinoblastoma)

Term
Colonies of mucois Pseudomonas in lungs
Definition

Cystic Fibrosis

(autosomal recessive mutation in CFTR gene > fat-soluble vitamin deficiency and mucous plugs)

Term
Decreased AFP in amniotic fluid/maternal serum
Definition
Down Syndrome or other chromosomal abnormality
Term
Degeneration of dorsal column nerves
Definition

Tabes Dorsalis (tertiary syphilis)

 

Subacute Combined Degeneration

(dorsal columns and lateral corticospinal tracts affected)

Term
Depigmentation of neurons in substantia nigra
Definition

Parkinson Disease

(Basal Ganglia disorder > rigidity, resting tremor, bradykinesia)

Term
Desquamated epithelium casts in sputum
Definition

Curschmann Spirals

 

(Bronchial asthma

Can cause whorled mucous plugs)

Term
Disarrayed granulosa cells in eosinphilic fluid
Definition

Call-Exner bodies

 

(granulosa-theca cell tumor of the ovary)

Term
Dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia
Definition

Koilocytes

(HPV: predisposes to cervical cancer)

Term
Enlarged cells with intranuclear inclusion bodies
Definition
"Owl eye" appearance of CMV
Term
Enlarged thyroid cells with ground-glass nuclei
Definition

"Orphan Annie" eyes nuclei

(Papillary Carcinoma of the Thyroid)

Term
Eosinophilic cytoplasmic inclusion in liver cell
Definition

Mallory body

(Alcoholic liver disease)

Term
Eosinophilic cytoplasmic inclusion in nerve cell
Definition

Lewy body

(Parkinson Disease)

Term
Eosinophilic globule in liver
Definition

Councilman body

 

(Toxic or Viral Hepatitis

Yellow Fever)

Term
Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar nerve cells
Definition
Negri bodies of rabies
Term
Extracellular amyloid deposition in gray matter of brain
Definition
Senile Plaques (Alzheimer Disease)
Term
Giant B-cells with bilobed nuclei with prominent inclusions ("owl's eye")
Definition

Reed-Sternberg cells

(Hodgkin Lymphoma)

Term
Glomerulus-like structure surrounding vessel in germ cells
Definition

Schiller-Duval bodies

(Yolk Sac tumors)

Term
"Hair on end" (crew-cut) appearance on x-ray
Definition

B-thalassemia

Sickle Cell Anemia

 

(marrow expansion)

Term
hCG elevated
Definition

Choriocarcinoma

 

Hydatidiform Mole

(occurs with and without embryo)

 

Multiple Pregnancy

Term
Heart nodules (Granulomatous)
Definition

Aschoff bodies

(Rheumatic Fever)

Term
Heterophile antibodies
Definition

Infectious mononucleosis

(EBV)

Term
Hexagonal, double-pointed, needle-like crystals in bronchial secretions
Definition

Bronchial Asthma

(Charcot-Leyden crystals: eosinophilic granules)

Term
High level of D-dimers
Definition

DVT

PE

DIC

Term

Hilar lymphadenopathy

Peripheral granulomatous lesion in middle or lower lung lobes (can calcify)

Definition

Ghon Complex

(primary TB: Mycobacterium bacilli)

Term
"Honeycomb lung" on x-ray or CT
Definition
Interstitial Pulmonary Fibrosis
Term

Hypercoagulability

(leading to migrating DVTs and vasculitis)

Definition

Trousseau Syndrome

(adenocarcinoma of pancreas or lung)

Term
Hypersegmented neutrophils
Definition

Megaloblastic anemia

 

B12 deficiency = neurologic symptoms

Folate deficiency = no neurologic symptoms

Term

HTN

Hypokalemia

Metabolic acidosis

Definition
Conn Syndrome
Term
Hypochromic, microcytic anemia
Definition

Iron deficiency anemia

 

Lead poisoning

 

Thalassemia

(fetal Hgb sometimes present)

Term
Increased AFP in amniotic fluid/maternal serum
Definition

Dating Error

 

Anencephaly

 

Spina Bifida

(neural tube defects)

Term
Increased uric acid levels
Definition

Gout

 

Lesch-Nyhan Syndrome

 

Tumor lysis syndrome

 

Loop and Thiazide diuretics

Term
Intranuclear eosinophilic droplet-like bodies
Definition

Cowdry type A bodies

 

(HSV

CMV)

Term
Iron-containing nodules in alveolar septum
Definition

Ferruginous bodies

(Asbestosis > increased chance of Mesothelioma)

Term
Keratin pearls on a skin biopsy
Definition
Squamous Cell Carcinoma
Term

Large lysosomal vesicles in phagocytes

Immunodeficiency

Definition

Chediak-Higashi disease

(congenital failure of phagolysosome formation due to microtubule defect)

Term
"Lead pipe" appearance of colon on barium enema x-ray
Definition

Ulcerative Colitis

(loss of haustra)

Term
Linear appearance of IgG deposition on glomerular basement membrane
Definition
Goodpasture Syndrome
Term
Low serum ceruloplasmin
Definition

Wilson Disease

(hepatolenticular degeneration)

Term
"Lumpy bumpy" appearance of glomeruli on immunofluorescence
Definition

Poststreptococcal glomerulonephritis

(immune complex deposition of IgG and C3b)

Term
Lytic ("hole punched") bone lesions on x-ray
Definition
Multiple Myeloma
Term
Mammary gland ("blue domed") cyst
Definition
Fibrocystic change of the breast
Term
Monoclonal antibody spike
Definition

Multiple Myeloma (IgG or IgA)

 

Monoclonal Gammopathy of undetermined significance (MGUS, consequence of aging)

 

Waldenstrom (M protein = IgM) Macroglobulinemia

 

Primary Amyloidosis

Term
Mucin-filled cell with peripheral nucleus
Definition

"Signet ring"

(Gastric Carcinoma)

Term

Necrotizing vasculitis (lungs)

Necrotizing Glomerulonephritis

Definition

Granulomatosis with Polyangiitis (Wegner: PR3-ANCA/c-ANCA)

 

Goodpasture Syndrome (anti-basement membrane antibodies)

Term
Needle-shaped, negatively birefringent crystals
Definition

Gout

(monosodium urate crystals)

Term
Nodular hyaline deposits in glomeruli
Definition

Kimmelstiel-Wilson nodules

(Diabetic Nephropathy)

Term
Novobiocin response
Definition

Sensitive = Staphylococcus epidermidis

 

Resistant = Staphylococcus saprophyticus

Term
"Nutmeg" appearance of liver
Definition
Chronic passive congestion of liver due to right heart failure
Term
"Onion skin" periosteal reaction
Definition

Ewing Sarcoma

(malignant round-cell tumor)

Term
Optochin response
Definition

Sensitive = Streptococcus pneumoniae

 

Resistant = Viridans streptococci

Term
Periosteum raised from bone > triangular area
Definition

Codman triangle on x-ray

 

(Osteosarcoma

Ewing Sarcoma

Pyogenic osteomyelitis)

Term
Podocyte fusion of "effacement" on electron microscopy
Definition

Minimal Change Disease

(child with nephrotic syndrome)

Term
Polished, "ivory-like" appearance of bone at cartilage erosion
Definition

Eburnation

(osteoarthritis resulting in bony sclerosis)

Term
Protein aggregates in neurons from hyperphosphorylation of tau protein
Definition

Neurofibrillary tangles (Alzheimer's disease)

 

Pick bodies (Pick disease)

Term
Psammoma bodies
Definition

Meningiomas

 

Papillary Thyroid Carcinoma

 

Mesothelioma

 

Papillary Serous Carcinoma (Endometrium and Ovary)

Term
Pseudopalisading tumor cells on brain biopsy
Definition
Glioblastoma Multiforme
Term
RBC casts in urine
Definition
Acute glomerulonephritis
Term
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells
Definition

Reinke Crystals

(Leydig cell tumor)

Term
Renal epithelial casts in urine
Definition
Acute toxic/viral renal injury
Term
Rhomboid crystals, positively birefringent
Definition

Pseudogout

(Calcium pyrophosphate dihydrate crystals)

Term
Rib notching
Definition
Coarctation of the aorta
Term
Ring-enhancing brain lesions in AIDS
Definition

Toxoplasma gondii

 

CNS Lymphoma

Term
Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ("starry sky" histology)
Definition

Burkitt Lymphoma

 

(t[8;14] c-myc activations

Associated with EBV

"Black sky" made up of malignant cells)

Term
Silver-staining spherical aggregation of tau proteins in neurons
Definition

Pick bodies

(Pick disease - progressive dementia, changes in personality)

Term
"Soap bubble" in femur or tibia on x-ray
Definition
Giant cell tumor of bone (generally benign)
Term

"Spikes" on basement membrane

"Dome-like" subepithelial deposits

Definition

Membranous glomerulonephritis

(may progress to nephrotic syndrome)

Term
Stacks of RBCs
Definition

Rouleaux formation

 

(High ESR

Multiple Myeloma)

Term
Stippled vaginal epithelial cells
Definition

"Clue Cells"

(Gardnerella vaginalis)

Term
"Tennis racket"-shaped cytoplasmic organelles (EM) in Langerhans cells
Definition

Birbeck Granules

 

(Langerhans Cell Histiocytosis or Histiocytosis X: eosinophilic granuloma)

Term
Thrombi made of white/red layers
Definition

Lines of Zahn

(arterial thrombus, layers of platelets/RBCs)

Term
"Thumb sign" on lateral x-ray
Definition

Epiglottitis

(Haemophilus influenzae)

Term
Thyroid-like appearance of kidney
Definition
Chronic bacterial pyelonephritis
Term
"Tram-track" appearance of capillary loops of glomerular basement membranes on light microscopy
Definition
Membranoproliferative glomerulonephritis
Term
Triglyceride accumulation in liver cell vacuoles
Definition

Fatty liver disease

(Alcoholic or Metabolic Syndrome)

Term
"Waxy" casts with very low urine flow
Definition
Chronic end-stage renal disease
Term
WBC casts in urine
Definition
Acute pyelonrphitis
Term
WBCs that look "smudged"
Definition

CLL

(almost always B-cell)

Term
"Wire loop" glomerular capillary appearance on light microscopy
Definition
Lupus Nephropathy
Term
Yellowish CSF
Definition

Xanthochromia

(Subarachnoid Hemorrhage)

Term
Sensitivity
Definition
TP/(TP + FN)
Term
Specificity
Definition
TN/(TN+FP)
Term
Positive Predictive Value
Definition
TP/(TP+FP)
Term
Negative Predictive Value
Definition
TN/(TN+FN)
Term

Odds Ratio

(for Case-Control studies)

Definition

(a/c)/(b/d)

 

or

 

ad/bc

Term
Relative Risk
Definition

a/(a+b)

c/(c+d)

Term
Attributable Risk
Definition
a/(a+b) - c/(c+d)
Term
Number Needed to Treat
Definition
1/absolute risk reduction
Term
Number Needed to Harm
Definition
1/attributal risk
Term
Hardy-Weinberg Equilibrium
Definition

p2 + 2pq + q2 = 1

 

p+q = 1

Term
Volume of Distribution
Definition

amount of drug in the body

plasma drug concentration

Term
Half-life
Definition

0.0693 x Vd

CL

Term
Drug Clearance
Definition

rate of elimination of drug

plasma drug concentration

 

or

 

Vd x Ke

 

(Ke = elimination constant)

Term
Loading Dose
Definition

Cp x Vd

F

Term
Maintenance Dose
Definition

Cp x CL x t

F

Term
Cardiac Output
Definition

rate of O2 consumption

arterial O2 content - venous O2 content

 

or

 

SV x HR

Term
Mean Arterial Pressure
Definition

CO x TPR

 

or

 

2/3 diastolic + 1/3 systolic

Term
Stroke Volume
Definition
EDV - ESV
Term
Ejection Fraction
Definition

SV

EDV

 

or

 

EDV - ESV

EDV

Term
Resistance
Definition

Driving Pressure (delta P)

Flow (Q)

 

or

 

8n (viscosity) x length

pi x r4

Term
Net Filtration Pressure
Definition

(Pc - Pi) - (pic - pii)

(out - in) - (in - out)

 

or

 

Jv = net fluid flow = (Kf)(Pnet)

Term
Renal Clearance
Definition
UxV/Px
Term
Glomerular Filtration Rate
Definition

Uinulin x V

Pinulin

 

or

 

Kf[(PGC - PBS) - (piGC - piBS)]

Term
Effective Renal Plasma Flow
Definition

UPAH x V

PPAH

Term
Renal Blood Flow
Definition

RPF

1 - Hct

Term
Filtration Fraction
Definition
GFR/RPF
Term

Henderson-Hasselbalch Equation

(for extracellular pH)

Definition

pH = 6.1 + log [HCO3-]

                       0.03 x [PCO2]

Term
Winters Formula
Definition
PCO2 = 1.5 x [HCO3-] + 8 + 2
Term
Physiologic Dead Space
Definition

VTPaCO2 - PECO2

     PaCO2

Term
Pulmonary Vascular Resistance
Definition

Ppulm artery - PL atrium

CO

Term
Alveolar Gas Equation
Definition

PAO2 = PIO2 - PaCO2

                      R

Term

Absence seizures

 

(Treatment)

Definition
Ethosuximide
Term

Acute Gout Attack

 

(Treatment)

Definition

NSAIDS

Colchicine

Term

Acute Promyelocytic Leukemia (M3)

 

(Treatment)

Definition
All-trans retinoic acid
Term

ADHD

 

(Treatment)

Definition

Methylphenidate

Amphetamines

Term

Alcohol Use Disorder

 

(Treatment)

Definition

AA +

Disulfiram,

Naltrexone, or

Acamprosate

 

A1-Anon for family

Term

Alcohol Withdrawal

 

(Treatment)

Definition
Benzodiazepines
Term

Anorexia

 

(Treatment)

Definition

Nutrition

Psychotherapy

Term

Anticoagulation during pregnancy

 

(Treatment)

Definition
Heparin
Term

Arrhythmia in damaged cardiac tissue

 

(Treatment)

Definition

Class IB antiarrhythmics

 

(Lidocaine

Mexiletine

Tocainide)

Term

B12 Deficiency

 

(Treatment)

Definition

Vitamin B12 supplementation

(work up cause with Schilling test)

Term

Benign prostatic Hyperplasia

 

(Treatment)

Definition

Tamulosin

Finasteride

Term

Bipolar Disorder

 

(Treatment)

Definition

Lithium

Valproate

Carbamazepine

Lamotrigine

 

(mood stabilizers)

Term

Breast cancer in postmenopausal woman

 

(Treatment)

Definition

Aromatase inhibitor

(Anastrozole)

Term

Buerger Disease

 

(Treatment)

Definition
Smoking cessation
Term

Bilimia Nervosa

 

(Treatment)

Definition
SSRIs
Term

Candida Albicans

 

(Treatment)

Definition

Systemic = Amphotericin B

 

Oral Thrush = Nystatin

 

Vaginitis = Azoles

Term

Carcinoid Syndrome

 

(Treatment)

Definition
Octreotide
Term

Chlamydia trachomatis

 

(Treatment)

Definition

Doxycycline

(+ Ceftriaxone for Gonorrhea coinfection)

 

Erytromycin eye drops

(prophylaxis in infants)

Term

Chronic Gout

 

(Treatment)

Definition

Probenecid (underexcretor)

 

Allopurinol (overproducer)

 

Febuxostat

Term

Chronic Hepatitis

 

(Treatment)

Definition
IFN-a
Term

Chronic Myelogenous Leukemia

(CML)

 

(Treatment)

Definition
Imatinib
Term

Clostridium botulinum

 

(Treatment)

Definition
Antitoxin
Term

Clostridium difficile

 

(Treatment)

Definition

Oral Metronidazole

 

If refractory, oral Vancomycin

Term

Clostridium tetani

 

(Treatment)

Definition
Antitoxin + Vaccine booster + Diazepam
Term

CMV

 

(Treatment)

Definition
Ganciclovir
Term

Crohn Disease

 

(Treatment)

Definition

Corticosteroids

Infliximab

Methotrexate

Azathioprine

Term

Crytoccocus neoformans

 

(Treatment)

Definition

Fluconazole

(propylaxis in AIDS patients)

Term

Cyclophosphamide-induced Hemorrhagic Cystitis

 

(Treatment)

Definition
Mesna
Term

Depression

 

(Treatment)

Definition

SSRIs

(first-line)

Term

Diabetes Insipidus

 

(Treatment)

Definition

Central = DDAVP

 

Nephrogenic:

Hydrochlorothiazide

Indomethacin

Amiloride

Term

Diabetes Mellitus Type 1

 

(Treatment)

Definition
Dietary intervention (low sugar) + Insulin
Term

Diabetes Mellitus Type 2

 

(Treatment)

Definition

Dietary intervention

Oral hypoglycemics

Insulin (if refractory)

Term

Diabetic Ketoacidodid

 

(Treatment)

Definition

Fluids

Insulin

K+

Term

Enterococci

 

(Treatment)

Definition
Vancomycin/Ampicillin + Aminoglycosides
Term

Erectile Dysfunction

 

(Treatment)

Definition

Sildenafil

Vardenafil

Term

ER+ Breast Cancer

 

(Treatment)

Definition
Tamoxifen
Term

Ethylene Glycol/Methanol Intoxication

 

(Treatment)

Definition

Fomepizole

(alcohol dehydrogenase inhibitor)

Term

iHaemophilus influenzae (B)

 

(Treatment)

Definition
Rifampin (prophylaxis)
Term

Generalized Anxiety Disorder

 

(Treatment)

Definition
Buspirone
Term

Granulomatosis with Polyangiitis (Wegner)

 

(Treatment)

Definition

Cyclophosphamide

Corticosteroids

Term

Heparin Toxicity (acute)

 

(Treatment)

Definition
Protamine sulfate
Term

Her2/neu+ Breast Cancer

 

(Treatment)

Definition
Trastuzumab
Term

Hyperaldosteronism

 

(Treatment)

Definition
Spironolactone
Term

Hypercholesterolemia

 

(Treatment)

Definition

Statins

(first-line)

Term

Hypertriglyceridemia

 

(Treatment)

Definition
Fibrate
Term

Immediate anticoagulation

 

(Treatment)

Definition
Heparin
Term

Infertility

 

(Treatment)

Definition

Leuprolide

GnRH (pulsatile)

Clomiphene

Term

Influenza

 

(Treatment)

Definition

Rimantadine

Oseltamivir

Term

Legionella pneumophila

 

(Treatment)

Definition
Erythromycin
Term

Long-term anticoagulation

 

(Treatment)

Definition
Warfarin
Term

Malaria

 

(Treatment)

Definition

Chloroquine/mefloquine (for blood schizont)

 

Primaquine (for liver hypnozoite)

Term

Malignant Hyperthermia

 

(Treatment)

Definition
Dantrolene
Term

Medial Abortion

 

(Treatment)

Definition
Mifepristone
Term

Migraine

 

(Treatment)

Definition
Sumatriptan
Term

MRSA

 

(Treatment)

Definition
Vancomycin
Term

Multiple Sclerosis

 

(Treatment)

Definition

B-interferon

Immunosuppression

Natalizumab

Term

Mycobacterium tuberculosis

 

(Treatment)

Definition

(RIPE)

 

Rifampin

INH

Pyrazinamide

Ethambutol

Term

Neisseria gonorrhoeae

 

(Treatment)

Definition

Ceftriaxone

(add Doxycycline to cover likely concurrent Chlamydia)

Term

Neisseria meningitidis

 

(Treatment)

Definition

Penicillin/Ceftriaxone

Rifampin (prophylaxis)

Term

Neural Tube defect prevention

 

(Treatment)

Definition
Prenatal folic acid
Term

Osteomalacia / Rickets

 

(Treatment)

Definition
Vitamin D supplementation
Term

Osteoporosis

 

(Treatment)

Definition

Bisphosphonates

Calcium + Vitamin D supplementation

Term

Patent Ductus Arteriosus

 

(Treatment)

Definition
Indomethacin
Term

Pheochromocytoma

 

(Treatment)

Definition

a-antagonists

(Phenoxybenzamine)

Term

Pneumocystic jirovecii

 

(Treatment)

Definition

TMP-SMX

(prophylaxis in AIDS)

Term

Prolactinoma

 

(Treatment)

Definition

Bromocriptine

(dopamine agonist)

Term

Prostate Cancer / Uterine Fibroids

 

(Treatment)

Definition

Leuprolide

GnRH (continuous)

Term

Prostate Carcinoma

 

(Treatment)

Definition
Flutamide
Term

Pseudomonas aeruginosa

 

(Treatment)

Definition
Antipseudomonal Penicillin + Aminoglycoside
Term

Pulmonary Arterial HTN (idiopathic)

 

(Treatment)

Definition

Sildenafil

Bosentan

Epoprostenol

Term

Rickettsia rickettsii

 

(Treatment)

Definition

Doxycycline

 

Chloramphenicol

(associated with aplastic anemia)

Term

Ringworm inefctions

 

(Treatment)

Definition

Terbinafine

Griseofulvin

Imidazole

Term

Schizophrenia (negative symptoms)

 

(Treatment)

Definition

5-HT2A antagonists

(2nd generation antipsychotics)

Term

Schizophrenia (positive symptoms)

 

(Treatment)

Definition

D2 receptor antagonists

(1st and 2nd generation antipsychotics)

Term

SIADH

 

(Treatment)

Definition

Demeclocycline

Lithium

Vasopressin receptor antagonists

Term

Sickle Cell Anemia

 

(Treatment)

Definition

Hydroxyurea

(increased fetal Hgb)

Term

Sporothrix schenkii

 

(Treatment)

Definition
Oral potassium iodide
Term

Stable Angina

 

(Treatment)

Definition
Sublingual nitroglycerin
Term

Staphylococcus aureus

 

(Treatment)

Definition

MSSA:

Nafcillin

Oxacillin

Dicloxacillin

(antistaphylococcal penicillins)

 

MRSA = Vancomycin

Term

Streptococcus bovis

 

(Treatment)

Definition

Penicillin prophylaxis

 

Evaluation for colon cancer if linked to endocarditis

Term

Streptococcus pneumoniae

 

(Treatment)

Definition

Systemic/Pneumonia = Penicillin/Cephalosporin

 

Meningitis = Vancomycin

Term

Temporal Arteritis

 

(Treatment)

Definition
High-dose steroids
Term

Tonic-Clonic Seizures

 

(Treatment)

Definition

Phenytoin

Carbamazepine

Valproate

Term

Toxoplasma gondii

 

(Treatment)

Definition
Sulfadiazine + Pyrimethamine
Term

Treponema pallidum

 

(Treatment)

Definition
Penicillin
Term

Trichomonas vaginalis

 

(Treatment)

Definition

Metronidazole

(patient AND partner)

Term

Trigeminal neuralgia (tic douloureux)

 

(Treatment)

Definition
Carbamazepine
Term

Ulcerative Colitis

 

(Treatment)

Definition

5-ASA

Infliximab

Colectomy

Term

UTI Prophylaxis

 

(Treatment)

Definition
TMP-SMX
Term

Warfarin Toxicity

 

(Treatment)

Definition

Acute = Fresh frozen plasma

 

Chronic = Vitamin K

Term
Actinic (solar) keratosis
Definition
Precursor to squamous cell carcinoma
Term
Acute gastric ulcer associated with CNS injury
Definition

Cushing ulcer

(increased intracranial pressure > vagal stimulation > gastric secretion)

Term
Acute gastric ulcer associated with severe burns
Definition

Curling ulcer

(greatly reduced plasma volume > sloughing of gastric mucosa)

Term
Alternating areas of transmural inflammation and normal colon
Definition

Skip lesions

(Crohn Disease)

Term
Aneurysm, dissecting
Definition
HTN
Term
Aortic aneurysm, abdominal and descending aorta
Definition
Atherosclerosis
Term
Aortic aneurysm, arch
Definition

Tertiary Syphilis (Syphilitic aortitis

Vasa Vasorum destruction

Term
Aortic aneurysm, ascending
Definition

Marfan syndrome

(idiopathic cystic medial degeneration)

Term
Atrophy of mammillary bodies
Definition

Wernicke encephalopathy

(Thiamine deficiency > ataxia, ophthalmoplegia, confusion)

Term

Autosplenectomy

(fibrosis and shrinkage)

Definition

Sickle Cell Anemia

(hemoglobin S)

Term
Bacteria associated with gastritis, peptic ulcer disease, and stomach cancer
Definition
H. pylori
Term

Bacterial meningitis

(adults and elderly)

Definition
Strep. pneumo
Term

Bacterial Meningitis

(newborns and kids)

Definition

Newborns = GBS, E. coli

 

Kids = S. pneumo, N. meningitidis

Term
Benign melanocytic nevus
Definition

Spitz nevus

(most common in 1st 2 decades)

Term
Bleeding disorder with GpIb deficiency
Definition

Bernard-Soulier Syndrome

(defect in platelet adhesion to von Willebrand factor)

Term

Brain tumor

(adults)

Definition

Supratentorial

 

Metastasis > Astrocytoma (GBM) > Meningioma > Schwannoma

Term

Brain tumor

(kids)

Definition

Infratentorial:

Medulloblastoma (cerebellum)

 

Supratentorial:

Craniopharyngioma

Term
Breast cancer
Definition
Infiltrating ductal carcinoma
Term
Breast mass
Definition

Fibrocystic change

Carcinoma (postmenopausal)

Term
Breast tumor (benign)
Definition
Fibroadenoma
Term
Cardiac Primary tumor (kids)
Definition

Rhabdomyoma

(seen with tuberous sclerosis0

Term
Cardiac manifestation of lupus
Definition

Libman-Sacks endocarditis

(nonbacterial, affects both sides of Mitral valve)

Term
Cerebellar tonsillar herniation
Definition
Chiari II malformation
Term
Chronic arrhythmia
Definition

Atrial fibrillation

(associated with high risk of emboli)

Term

Chronic atrophic gastritis

(autoimmune)

Definition

Predisposition to gastric carcinoma

(can also cause Pernicious Anemia)

Term
Clear cell adenocarcinoma of the vagina
Definition
DES exposure in utero
Term
Compression fracture
Definition

Osteoporosis

 

Type 1 = postmenopausal woman

Type 2 = elderly man or woman

Term
Congenital Adrenal Hyperplasia + Hypotension
Definition
21-hydroxylase deficiency
Term
Congenital Cardiac anomaly
Definition
VSD
Term

Congenital conjugated hyperbilirubinemia

(black liver)

Definition

Dubin-Johnson syndrome

(inability of hepatocytes to secrete conjugated bilirubin into bile)

Term
Constrictive pericarditis
Definition

Developing world = TB

 

Developed world = SLE

Term
Coronary artery involved in thrombosis
Definition
LAD > RCA > LCA
Term
Cretinism
Definition

Iodine deficiency

Hypothyroidism

Term
Tumor in women
Definition

Leiomyoma

(estrogen dependent, not precancerous)

Term
Tumor of infancy
Definition

Hemangioma

(usually regresses spontaneously by childhood)

Term

Tumor of the adrenal medulla

(adults)

Definition

Pheochromocytoma

(usually benign)

Term

Tumor of the adrenal medulla

(kids)

Definition

Neuroblastoma

(malignant)

Term
Type of Hodgkin
Definition

Nodular sclerosis

 

(vs. Mixed cellularity, Lymphocytic predominance, Lymphocytic depletion)

Term
Type of non-Hodgkin
Definition
Diffuse large cell
Term
UTI
Definition

E. coli

Staph. saprophyticus (young women)

Term
Viral encephalitis affecting temporal lobe
Definition
HSV-1
Term

Vitamin deficiency

(U.S.)

Definition

Folate

(pregnant women are at high risk; body stores only 3-4 month supply; prevents neural tube defects)

Term

Ovarian tumor

(malignant)

Definition
Serous Cystadenocarcinoma
Term

Pancreatitis

(acute)

Definition

Gallstones

Alcohol

Term

Pancreatitis

(chronic)

Definition

Adults = Alcohol

 

Kids = Cystic fibrosis

Term
Patient with ALL/CLL/AML/CML
Definition

ALL = child

CLL = adult > 60

AML = adult ~65

CML = adult 30-60

Term
Pelvic inflammatory disease
Definition

Chlamydia trachomatis

N. gonorrhoeae

Term
Philadelphia chromosome t(9;22) (bcr-abl)
Definition

CML

Somtimes ALL/AML

Term
Pituitary tumor
Definition

Prolactinoma

Somatotropic acidophilic adenoma

Term
Primary amenorrhea
Definition
Turner Syndrome (45,XO)
Term

Primary bone tumor

(adults)

Definition
Multiple Myeloma
Term
Primary hyperaldosteronism
Definition
Adenoma of adrenal cortex
Term
Primary hyperparathyroidism
Definition

Adenoma

Hyperplasia

Carcinoma

Term
Primary liver cancer
Definition

Hepatocellular carcinoma

(Chronic hepatitis, Cirrhosis, Hemochromatosis, a1-antitrypsin deficiency)

Term
Pulmonary HTN
Definition
COPD
Term
Recurrent inflammation/thrombosis of medium/small vessels in extremeties
Definition

Buerger disease

(strongly associated with tobacco)

Term
Renal tumor
Definition

Renal cell carcinoma

 

Associated with VHL and cigarette smoking

 

Paraneoplastic syndromes:

Renin

ACTH

PTH

EPO

Term
Right heart failure due to pulmonary cause
Definition
Cor pulmonale
Term

S3

(protodiastolic gallop)

Definition

Increased ventricular filling

 

Causes:

Left-to-right shunt

Mitral regurgitation

LV failure (CHF)

Term

S4

(presystolic gallop)

Definition

Stiff/hypertrophic ventricle

 

Causes:

Aortic stenosis

Restrictive cardiomyopathy

Term
Secondary Hyperparathyroidism
Definition
Hypocalcemia of chronic kidney disease
Term
Sexually transmitted disease
Definition

Chlamydia

(usually coinfected with gonorrhea)

Term
SIADH
Definition
Small cell carcinoma of the lung
Term
Site of diverticula
Definition
Sigmoid colon
Term
Site of atherosclerosis
Definition
Abdominal aorta > Coronary artery > Popliteal artery > Carotid artery
Term
Stomach cancer
Definition
Adenocarcinoma
Term
Stomach ulcerations and high gastrin levels
Definition

Zollinger-Ellison syndrome

(gastrinoma of duodenum or pancreas)

Term
t(14;18)
Definition
Follicular lymphomas (bcl-2 activation)
Term
t(8;14)
Definition

Burkitt Lymphoma

(c-myc activation)

Term
t(9;22)
Definition

Philadelphia chromosome > CML

(bcr-abl fusion)

Term
Temporal arteritis
Definition

Risk of ipsilateral blindness due to thrombosis of ophthalmic artery

Polymyalgia rheumatica

Term
Testicular Tumor
Definition

Seminom

(malignant, radiosensitive)

Term
Thyroid Cancer
Definition
Papillary carcinoma
Term
Cushing Syndrome
Definition

Iatrogenic Cushing (corticosteroid therapy)

 

Adrenocortical adenoma (secretes excess cortisol)

 

ACTH-secreting pituitary adenoma

 

Paraneoplastic Cushing (ACTH secretion by tumors)

Term

Cyanosis

(early; less common)

Definition

Tetralogy of Fallot

Transposition of Great vessels

Truncus Arteriosus

Term

Cyanosis

(late; more common)

Definition

VSD

ASD

PDA

Term
Death in CML
Definition
Blast crisis
Term
Death in SLE
Definition
Lupus nephropathy
Term
Dementia
Definition

Alzheimer disease

Multiple infarcts

Term
Demyelinating disease in young women
Definition
Multiple Sclerosis
Term
DIC
Definition

Severe sepsis

Obstetric complications

Cancer

Burns

Trauma

Major surgery

Term
Dietary deficit
Definition
Iron
Term
Diverticulum in pharynx
Definition

Zenker diverticulum

(diagnosed by barium swallow)

Term
Ejection click
Definition
Aortic/Pulmonic stenosis
Term
Esophageal Cancer
Definition

Worldwide = Squamous cellc arcinoma

 

U.S. = Adenocarcinoma

Term

Food Poisoning

(exotoxin mediated)

Definition

S. aureus

B. cereus

Term

Glomerulonephritis

(adults)

Definition

Berger disease

(IgA Nephropathy)

Term
Gynecologic malignancy
Definition

U.S. = Endometrial carcinoma

 

Worldwide = Cervical carcinoma

Term
Congenital heart murmur
Definition
Mitral valve prolapse
Term
Heart valve in bacterial endocarditis
Definition
Mitral > Aortic (Rheumatic Fever), Tricuspid (IV drug abuse)
Term

Helminth infection

(U.S.)

Definition

Enterobius vermicularis

 

Ascaris lumbricoides

Term
Hematoma - Epidural
Definition

RUpture of Middle Meningeal artery

(Trauma; lentiform shaped)

Term
Hematoma - Subdural
Definition

Rupture of bridging veins

(crescent shaped)

Term
Hemochromatosis
Definition

Multiple blood transfusions

Hereditary HFE mutation

 

(Can cause:

CHF

"Bronze diabetes"

increased risk of hepatocellular carcinoma)

Term
Hepatocellular carcinoma
Definition

Cirrhotic liver

(associated with Hepatitic B and C and Alcoholism)

Term
Hereditary Bleeding disorder
Definition
von Willebrand disease
Term
Hereditary harmless jaundice
Definition

Gilbert Syndrome

(benign congenital unconjugated hyperbilirubinemia)

Term
HLA-B27
Definition

Ankylosing Spondylitis

 

Reactive Arthritis

 

Ulcerative Colitis

 

Psoriatic Arthritis

Term
HLA-DR3 or -DR4
Definition

DMT1

 

SLE

 

RA

Term
Holosystolic murmu
Definition

VSD

 

Tricuspid Regurgitation

 

Mitral Regurgitation

Term

Hypercoagulability

Endothelial damage

Blood Stasis

Definition

Virchow's Triad

(causes venous thrombosis)

Term
Secondary HTN
Definition
Renal disease
Term
Hypoparathyroidism
Definition
Accidental excision during thyroidectomy
Term
Hypopituitarism
Definition

Pituitary adenoma

(usually benign tumor)

Term
Infection secondary to blood transfusion
Definition
Hepatitis C
Term
Infections in chronic granulomatous disease
Definition

(Catalase +)

 

Staph. aureus

E. coli

Aspergillus

Term
Intellectual Disability
Definition

Down Syndrome

 

Fragile X Syndrome

Term
Kidney Stones
Definition

Calcium = radiopaque

 

Struvite (ammonium) = radiopaque

(formed by urease + organisms like Proteus vulgaris or Staph)

 

Uric acid = radiolucent

Term

Late cyanotic shunt

(uncorrected left to right becomes right to left)

Definition

Eisenmenger syndrome

 

Causes:

ASD

VSD

PDA

 

Results in pulmonary HTN and polycythemia

Term
Liver disease
Definition
Alcoholic cirrhosis
Term
Lysosomal storage disease
Definition
Gaucher disease
Term
Male cancer
Definition
Prostatic cancer
Term
Malignancy associated with noninfectious fever
Definition
Hodgkin Lymphoma
Term

Malignancy

(kids)

Definition

ALL

Medulloblastoma (cerebellum)

Term
Metastases to bone
Definition

Prostate / Breast > Lung > Thyroid

 

(+ Kidney)

 

BLT with a Kosher Pickle

Term
Metastases to brain
Definition
Lung > Breast > Genitourinary > Melanoma > GI
Term
Metastases to liver
Definition
Colon >> Stomach / Pancreas
Term
Mitochondrial Inheritance
Definition
Disease occurs in both males and females, inherited through females only
Term
Mitral valve stenosis
Definition
Rheumatic heart disease
Term
Mixed (UMN and LMN) motor neuron disease
Definition
Amyotrophic lateral sclerosis
Term
Myocarditis
Definition
Coxsackie B
Term

Nephrotic Syndrome

(adults)

Definition
Focal Segmental Glomerulosclerosis
Term

Nephrotic Syndrome

(kids)

Definition
Minimal Change Disease
Term
Neuron migration failure
Definition

Kallmann syndrome

 

(Hypogonadotropic hypogonadism + Anosmia)

Term
Nosocomial Pneumonia
Definition

Klebsiella

 

E. coli

 

Pseudomonas aeruginosa

Term
Obstruction of male urinary tract
Definition
BPH
Term
ng snap
Definition
Mitral stenosis
Term
Opportunistic infection in AIDS
Definition
Pneumocystic jirovecii pneumonia
Term
Osteomyelitis
Definition
S. aureus
Term
Osteomyelitis in Sickle CEll Disease
Definition
Salmonella
Term
eomyelitis with IV drug use
Definition

Pseudomonas

S. aureus

Term
Ovarian metastasis from gastric carcinoma or breast cancer
Definition

Krukenberg tumor

(mucin-secreting signet-ring cells)

Term

Ovarian tumor

(benign, bilateral)

Definition
Serous cystadenoma
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