Term
Abdominal pain
Ascites
Hepatomegaly |
|
Definition
Budd-Chiari Syndrome
(posthepatic venous thrombosis) |
|
|
Term
|
Definition
Familial Hypercholesterolemia
(decreased LDL receptor signaling) |
|
|
Term
Adrenal hemorrhage
Hypotension
DIC |
|
Definition
Waterhouse-Friderichsen Syndrome
(Meningococcemia) |
|
|
Term
|
Definition
Anterior Cruciate ligament injury |
|
|
Term
Arachnodactyly
Lens dislocation
Aortic dissection
Hyperflexible joints |
|
Definition
Marfan Syndrome
(Fibrillin defect) |
|
|
Term
Athlete with polycythemia |
|
Definition
Secondary to erythropoietin injection |
|
|
Term
Back pain
Fever
Night sweats
Weight loss |
|
Definition
Pott Disease
(Vertebral TB) |
|
|
Term
Bilateral hilar adenopathy
Uveitis |
|
Definition
Sarcoidosis
(Noncaseating granulomas) |
|
|
Term
|
Definition
Osteogenesis Imperfecta
(Type I collagen defect) |
|
|
Term
|
Definition
Burton Line
(Lead poisoning) |
|
|
Term
Bone pain
Bone enlargement
Arthritis |
|
Definition
Paget Disease of Bone
(increased osteoblastic and osteoclastic activity) |
|
|
Term
Bounding pulses
Diastolic heart murmur
Head bobbing |
|
Definition
|
|
Term
"Butterfly" facial rash
Raynaud phenomenon
Young female |
|
Definition
Systemic Lupus Erythematosus (SLE) |
|
|
Term
Cafe-au-lait spots
Lisch nodules (iris hamartoma) |
|
Definition
Neurofibromatosis Type I
(pheochromocytoma, optic gliomas) |
|
|
Term
Cafe-au-lait spots
Polyostotic fibrous dysplasia
Precocious puberty
Multiple endocrine abnormalities |
|
Definition
McCune-Albright Syndrome
(mosaic G-protein signaling mutation) |
|
|
Term
|
Definition
Muscular Dystrophy [usually Duchenne]
(X-linked recessive deletion of dystrophin gene) |
|
|
Term
"Cherry-red spots" on macula |
|
Definition
Tay-Sachs (ganglioside accumulation)
Niemann-Pick (sphingomyelin accumulation)
Central Retinal artery occlusion |
|
|
Term
|
Definition
Angina
(Stable: with moderate exertion
Unstable: with minimal exertion) |
|
|
Term
Chest pain
Pericardial effusion/friction rub
Persistent fever following MI |
|
Definition
Dressler Syndrome
(autoimmune-mediated post-MI fibrinous pericarditis
1-12 weeks after acute episode) |
|
|
Term
Child uses arms to stand up from squat |
|
Definition
Gowers sign
(Duchenne Muscular Dystrophy) |
|
|
Term
Child with fever later develops red rash on face that spreads to body |
|
Definition
"Slapped cheeks" - Erythema Infectiosum/Fifth Disease
(Parvovirus B19) |
|
|
Term
Chorea
Dementia
Caudate degeneration |
|
Definition
Huntington Disease
(autosomal dominant CAG repeat expansion) |
|
|
Term
Chronic exercise intolerance
Myalgia
Fatigue
Painful cramps
Myoglobinuria |
|
Definition
McArdle Disease
(muscle glycogen phosphorylase deficiency) |
|
|
Term
Conjugate lateral gaze palsy
Horizontal diplopia |
|
Definition
Internuclear Ophthalmoplegia
(damage to MLF)
Bilateral = Multiple Sclerosis
Unilateral = Stroke |
|
|
Term
Continuous "machine-like" heart murmur |
|
Definition
PDA
(Close with Indomethacin
Open/Maintain with Misoprostal [PGE]) |
|
|
Term
Cutaneous/dermal edema due to connective tissue deposition |
|
Definition
Myxedema
(Cause:
Hypothyroidism
Graves disease [pretibial]) |
|
|
Term
Dark purple skin/mouth nodules in a patient with AIDS |
|
Definition
Kaposi Sarcoma
(associated with HHV-8) |
|
|
Term
Deep, labored breathing
Hyperventilation |
|
Definition
Kussmaul Respirations
(Diabetic Ketoacidosis) |
|
|
Term
Dermatitis
Dementia
Diarrhea |
|
Definition
Pellagra
(Niacin [vitamin B3] deficiency) |
|
|
Term
Dilated cardiomyopathy
Edema
Alcoholism or Malnutrition |
|
Definition
Wet Beriberi
(Thiamine [vitamin B1] deficiency) |
|
|
Term
Dog or cat bite > infection |
|
Definition
Pasteurella multocida
(cellulitis at inoculation site) |
|
|
Term
Dry eyes
Dry mouth
Arthritis |
|
Definition
Sjogren Syndrome
(autoimmune destruction of exocrine glands) |
|
|
Term
Dysphagia (esophageal webs)
Glossitis
Iron deficiency anemia |
|
Definition
Plummer-Vinson Syndrome
(may progress to esophageal squamous cell carcinoma) |
|
|
Term
Elastic skin
Hypermobility of joints |
|
Definition
Ehlers-Danlos Syndrome
(Type III collagen defect) |
|
|
Term
Enlarged, hard left supraclavicular node |
|
Definition
Virchow node
(Abdominal metastasis) |
|
|
Term
Erythroderma
Lymphadenopathy
Hepatosplenomegaly
Atypical T-cells |
|
Definition
Mycosis Fungoides (cutaneous T-cell lymphoma)
Sezary Syndrome (mycosis fungoides + malignant T-cells in blood) |
|
|
Term
Facial muscle spasm upon tapping |
|
Definition
Chvostek sign
(Hypocalcemia) |
|
|
Term
|
Definition
Cholelithiasis
(gallstones) |
|
|
Term
Fever
Chills
Headache
Myalgia
Following antibiotic treatment for Syphilis |
|
Definition
Jarisch-Herxheimer Reaction
(rapid lysis of spirochetes results in toxin release) |
|
|
Term
Fever
Cough
Conjunctivitis
Coryza
Diffuse rash |
|
Definition
|
|
Term
Fever
Night sweats
Weight loss |
|
Definition
B-symptoms (staging) of lymphoma |
|
|
Term
Fibrous plaques in soft tissue of penis |
|
Definition
Peyronie Disease
(connective tissue disorder) |
|
|
Term
Gout
Intellectual disability
Self-mutilating behavior
Boy |
|
Definition
Lesch-Nyhan Syndrome
(HGPRT deficiency, x-linked recessive) |
|
|
Term
Green-yellow rings around peripheral cornea |
|
Definition
Kayser-Fleischer rings
(copper accumulation from Wilson disease) |
|
|
Term
Hamartomatous GI polyps
Hyperpigmentation of mouth/feet/hands |
|
Definition
Peutz-Jeghers Syndrome
(inherited, benign polyposis > bowel obstruction
increased cancer risk [mostly GI]) |
|
|
Term
Hepatosplenomegaly
Osteoporosis
Neurologic symptoms |
|
Definition
Gaucher Disease
(glucocerebrosidase deficiency) |
|
|
Term
Hereditary nephritis
Sensorineural hearing loss
Cataracts |
|
Definition
Alport Syndrome
(mutation in collagen IV) |
|
|
Term
Hyperphagia
Hypersexuality
Hyperorality
Hyperdocility |
|
Definition
Kluver-Bucy Syndrome
(bilateral amygdala lesion) |
|
|
Term
Hyperreflexia
Hypertonia
Babinski sign present |
|
Definition
|
|
Term
Hyporeflexia
Hypotonia
Atrophy
Fasciculations |
|
Definition
|
|
Term
Hypoxemia
Polycythemia
Hypercapnia |
|
Definition
"Blue Bloater" - Chronic Bronchitis
(hyperplasia of mucous cells) |
|
|
Term
Indurated, ulcerated genital lesion |
|
Definition
Nonpainful = Chancre (Primary Syphilis, Treponema pallidum)
Painful with exudate = Chancroid (Haemophilus ducreyi) |
|
|
Term
Infant with cleft lip/palate
Microcephaly or Holoprosencephaly
Polydactyly
Cutis aplasia |
|
Definition
Patau Syndrome
(Trisomy 13) |
|
|
Term
Infant with failure to thrive
Hepatosplenomegaly
Neurodegeneration |
|
Definition
Niemann-Pick Disease
(genetic sphingomyelinase deficiency) |
|
|
Term
Infant with hypoglycemia
Failure to thrive
Hepatomegaly |
|
Definition
Cori Disease (debranching enzyme deficiency)
Von Gierke Disease (glucose-6-phosphatase deficiency [more severe!]) |
|
|
Term
Infant with microcephaly
Rocker-bottom feet
Clenched hands
Structural heart defect |
|
Definition
Edwards Syndrome
(Trisomy 18) |
|
|
Term
Jaundice
Palpable distended non-tender gallbladder |
|
Definition
Courvoisier Sign
(distal obstruction of biliary tree) |
|
|
Term
Large rash with bull's-eye appearance |
|
Definition
Erythema Chronicum Migrans from Ixodes tick bite
(Lyme Disease: Borrelia burgdorferi) |
|
|
Term
Lucid interval after traumatic brain injury |
|
Definition
Epidural Hematoma
(Middle Meningeal artery rupture) |
|
|
Term
Male child
Recurrent infections
No mature B-cells |
|
Definition
Bruton Disease
(X-linked agammaglobulinemia) |
|
|
Term
Mucosal bleeding
Prolonged bleeding time |
|
Definition
Glanzmann Thrombasthenia
(defect in platelet aggregation due to lack of GpIIb/IIIa) |
|
|
Term
Muffled heart sounds
Distended neck veins
Hypotension |
|
Definition
Beck Triad of Cardiac Tamponade |
|
|
Term
Multiple colon polyps
Osteomas/soft tissue tumors
Impacted/supernumerary teeth |
|
Definition
Gardner Syndrome
(subtype of FAP) |
|
|
Term
Myopathy (infantile hypertrophic cardiomyopathy)
Exercise intolerance |
|
Definition
Pompe Disease
(lysosomal a-1,4-glucosidase deficiency) |
|
|
Term
Neonate with arm paralysis following difficult birth |
|
Definition
Erb-Duchenne Palsy
(superior trunk [C5-C6] brachial plexus injury
"Waiter's tip") |
|
|
Term
No lactation postpartum
Absent menstruation
Cold intolerance |
|
Definition
Sheehan Syndrome
(pituitary infarction) |
|
|
Term
Nystagmus
Intention tremor
Scanning speech
Bilateral internuclear ophthalmoplegia |
|
Definition
Multiple Sclerosis
(autoimmune destruction of oligodendrocytes) |
|
|
Term
Oscillating slow/fast breathing |
|
Definition
Cheyne-Stokes respirations
(central apnea in CHF or increased intracranial pressure) |
|
|
Term
Painful blue fingers/toes
Hemolytic anemia |
|
Definition
Colg agglutinin disease
(autoimmune hemolytic anemia caused by Mycoplasma pneumoniae, infectious Mononucleosis) |
|
|
Term
Painful, pale, cold fingers/toes |
|
Definition
Raynaud Phenomenon
(vasospasm in extremities) |
|
|
Term
Painful, raised red lesions on pad of fingers/toes |
|
Definition
Osler nodes
(Causes:
Infective endocarditis
Immune complex deposition) |
|
|
Term
Painless erythematous lesions on palms and soles |
|
Definition
Janeway Lesions
(Causes:
Infective endocarditis
Septic emboli/microabscesses) |
|
|
Term
|
Definition
Cancer of pancreatic head obstructive bile duct |
|
|
Term
Palpable purpura on buttocks/legs
Joint pain
Abdominal pain (child)
Hematuria |
|
Definition
Henoch-Schonlein Purpura
(IgA vasculitis affecting skin and kidneys) |
|
|
Term
Pancreatic, Pituitary, Parathyroid tumors |
|
Definition
MEN 1
(autosomal dominant) |
|
|
Term
Periorbital and/or peripheral edema
Proteinuria
Hypoalbuminemia
Hypercholesterolemia |
|
Definition
|
|
Term
Pink complexion
Dyspnea
Hyperventilation |
|
Definition
"Pink Puffer" - Emphysema
(Centriacinar [smoking], Panacinar [a1-antitrypsin deficiency]) |
|
|
Term
Polyuria
Renal tubular acidosis type II
Growth failure
Electrolyte imbalances
Hypophosphatemic rickets |
|
Definition
Fanconi Syndrome
(Proximal tubular reabsorption defect) |
|
|
Term
Pruritic, purple, polygonal planar papules and plaques
(6 P's) |
|
Definition
|
|
Term
|
Definition
Horner Syndrome
(sympathetic chain lesion) |
|
|
Term
Pupil accomodates but doesn't react |
|
Definition
Argyll Robertson pupil
(Neurosyphilis) |
|
|
Term
Rapidly progressive leg weakness that ascends following GI/upper respiratory infection |
|
Definition
Guillain-Barre Syndrome
(acute autoimmune inflammatory demyelinating polyneuropathy that attach Schwann cells) |
|
|
Term
|
Definition
Coxsackie A
Secondary Syphilis
Rocky Mountain Spotted Fever |
|
|
Term
Recurrent colds
Unusual eczema
High serum IgE |
|
Definition
Hyper-IgE Syndrome
(Job Syndrome - neutrophil chemotaxis abnormality) |
|
|
Term
Red "currant jelly" sputum in alcoholic or diabetic patients |
|
Definition
|
|
Term
Red "currant jelly" stools |
|
Definition
Acute mesenteric ischemia (adults)
Intussusception (infants) |
|
|
Term
Red, itchy, swollen rash of nipples/areola |
|
Definition
Paget disease of the breast
(signs of underlying neoplasm) |
|
|
Term
Red urine in morning
Fragile RBCs |
|
Definition
Paroxysmal Nocturnal Hemoglobinuria |
|
|
Term
Renal cell carcinoma (bilateral)
Hemangioblastomas
Angiomatosis
Pheochromocytoma |
|
Definition
von Hippel-Lindae disease
(dominant tumor suppressor gene mutation) |
|
|
Term
Resting tremor
Rigidity
Akinesia
Postural instability |
|
Definition
Parkinson disease
(nigrostriatal dopamine depletion) |
|
|
Term
Retinal hemorrhages with pale centers |
|
Definition
Roth spots
(bacterial endocarditis) |
|
|
Term
Severe jaundice in neonate |
|
Definition
Crigler-Najjar syndrome
(congenital unconjugated hyperbilirubinemia) |
|
|
Term
Severe RLQ pain with palpation of LLQ |
|
Definition
Rovsing sign
(acute appendicitis) |
|
|
Term
Severe RLQ pain with rebound tenderness |
|
Definition
McBurney Sign
(acute appendicitis) |
|
|
Term
Short stature
Increased incidence of tumors/leukemia
Aplastic anemia |
|
Definition
Fanconi Anemia
(genetic loss of DNA crosslink repair
often progresses to AML) |
|
|
Term
|
Definition
|
|
Term
Situs inversus
Chronic sinusitis
Bronchiectasis
Infertility |
|
Definition
Kartagener Syndrome
(dynein arm defect affecting cilia) |
|
|
Term
Skin hyperpigmentation
Hypotension
Fatigue |
|
Definition
Addison Disease
(primary adrenocortical insufficiency > increased ACTh and a-mSH production) |
|
|
Term
Slow, progressive muscle weakness in boys |
|
Definition
Becker Muscular Dystrophy
(X-linked missense mutation in dystrophin
Less severe than Duchenne) |
|
|
Term
Small, irregular red spots on buccal/lingual mucosa with blue-white centers |
|
Definition
Koplik Spots
(Causes:
Measles
Rubeola virus) |
|
|
Term
Smooth, flat, moist, painless white lesions on genital |
|
Definition
Condylomata lata
(Secondary Syphilis) |
|
|
Term
Splinter hemorrhages in fingernails |
|
Definition
|
|
Term
|
Definition
Scarlet Fever
Kawasaki Disease
Toxic Shock Syndrome |
|
|
Term
Streak ovaries
Congenital heart disease
Horseshoe kidney
Cystic hygroma at birth
Short stature
Webbed beck
Lymphedema |
|
Definition
|
|
Term
Sudden swollen/painful big toe joint
Tophi |
|
Definition
Gout/Podagra
(hyperuricemia) |
|
|
Term
Swollen gums
Mucosal bleeding
Poor wound healing
Patechiae |
|
Definition
Scurvy
(Vitamin C deficiency > can't hydroxylate proline/lysine for collagen synthesis) |
|
|
Term
Swollen, hard, painful finger joints |
|
Definition
Osteoarthritis
Bouchard nodes = osteophytes on PIP
Heberden nodes = osteophytes on DIP |
|
|
Term
Systolic ejection murmur (crescendo-decrescendo) |
|
Definition
|
|
Term
Thyroid and parathyroid tumors
Pheochromocytoma |
|
Definition
MEN 2A
(autosomal dominant ret mutation) |
|
|
Term
Thyroid tumors
Pheochromocytoma
Ganglioneuromatosis |
|
Definition
MEN 2B
(autosomal dominant ret mutation) |
|
|
Term
Toe extension/fanning upon plantar scrape |
|
Definition
Babinski sign
(UMN lesion) |
|
|
Term
Unilateral facial drooping involving forehead |
|
Definition
Facial nerve
(LMN CN 7 palsy) |
|
|
Term
Urethritis
Conjunctivitis
Arthritis
Male |
|
Definition
Reactive arthritis associated with HLA-B27 |
|
|
Term
Vascular birthmark (port-wine stain) |
|
Definition
Hemangioma
(benign, but associated with Sturge-Weber syndrome) |
|
|
Term
Vomiting blood following gastroesophageal lacerations |
|
Definition
Mallory-Weiss Syndrome
(alcoholic and bulimic patients) |
|
|
Term
Weight loss
Diarrhea
Arthritis
Fever
Adenopathy |
|
Definition
Whipple Disease
(Tropheryma whipplei) |
|
|
Term
"Worst headache of my life" |
|
Definition
|
|
Term
Anticentromere antibodies
|
|
Definition
|
|
Term
Antidesmoglein (epithelial) antibodies |
|
Definition
Pemphigus Vulgaris
(blistering) |
|
|
Term
Anti-glomerular basement membrane antibodies |
|
Definition
Goodpasture Syndrome
(glomerulonephritis and hemoptysis) |
|
|
Term
|
Definition
Drug-induced SLE
(Hydralazine
INH
Phenytoin
Procainamide) |
|
|
Term
|
Definition
Rheumatoid Arthritis
(systemic inflammation, joint pannus, boutonniere deformity) |
|
|
Term
Antimitochondrial antibodies (AMAs) |
|
Definition
Primary Biliary Cirrhosis
(female, cholestasis, portal HTN) |
|
|
Term
Antineutrophil Cytoplasmic antibodies (ANCAs) |
|
Definition
Microscopic Polyangiitis
Churg-Strauss Syndrome
(MPO-ANCA/p-ANCA)
Granulomatosis with Polyangiitis
(Wegener: PR3-ANCA/c-ANCA) |
|
|
Term
Antinuclear antibodies
(ANAs: anti-Smith and anti-dsDNA) |
|
Definition
SLE
(Type III hypersensitivity) |
|
|
Term
|
Definition
Idiopathic Thrombocytopenic Purpura |
|
|
Term
Anti-topoisomerase antibodies |
|
Definition
Diffuse Systemic Scleroderma |
|
|
Term
Anti-transglutaminase
Anti-gliadin
Anti-endomysial |
|
Definition
Celiac disease
(diarrhea, distention, weight loss) |
|
|
Term
"Apple core" lesion on abdominal x-ray |
|
Definition
Colorectal cancer
(usually left-sided) |
|
|
Term
Azurophilic peroxidase positive granular inclusions in granulocytes and myeloblasts |
|
Definition
Auer Rods
(AML, especially promyelocytic [M3] type) |
|
|
Term
|
Definition
Sensitive = Streptococcus pyogenes (group A)
Resistant = Streptococcus agalactiae (group B) |
|
|
Term
|
Definition
Anklylosing Spondylitis
(chronic inflammatory arthritis
HLA-B27) |
|
|
Term
Basophilic nuclear remnants in RBCs |
|
Definition
Howell-Jolly bodies
(due to splenectomy or nonfunctional spleen) |
|
|
Term
Basophilic stippling of RBCs |
|
Definition
Lead poisoning
Sideroblastic anemia |
|
|
Term
|
Definition
|
|
Term
"Boot-shaped" heart on x-ray |
|
Definition
|
|
Term
Branching gram-positive rods with sulfur granules |
|
Definition
|
|
Term
Bronchogenic apical lung tumor on imaging |
|
Definition
Pancoast Tumor
(can compress sympathetic ganglion > Horner Syndrome) |
|
|
Term
|
Definition
Hyperparathyroidism
Osteitis Fibrosa Cystica
(deposited hemosiderin from hemorrhage > brown color) |
|
|
Term
Cardiomegaly with apical atrophy |
|
Definition
Chagas disease
(Trypanosoma cruzi) |
|
|
Term
Cellular crescents on Bowman capsule |
|
Definition
Rapidly progressive crescentic glomerulonephritis |
|
|
Term
"Chocolate cyst" of ovary |
|
Definition
Endometriosis
(frequently involves both ovaries) |
|
|
Term
Circular grouping of dark tumor cells surrounding pale neutrophils |
|
Definition
Homer-Wrist rosettes
(Neuroblastoma
Medulloblastoma
Retinoblastoma) |
|
|
Term
Colonies of mucois Pseudomonas in lungs |
|
Definition
Cystic Fibrosis
(autosomal recessive mutation in CFTR gene > fat-soluble vitamin deficiency and mucous plugs) |
|
|
Term
Decreased AFP in amniotic fluid/maternal serum |
|
Definition
Down Syndrome or other chromosomal abnormality |
|
|
Term
Degeneration of dorsal column nerves |
|
Definition
Tabes Dorsalis (tertiary syphilis)
Subacute Combined Degeneration
(dorsal columns and lateral corticospinal tracts affected) |
|
|
Term
Depigmentation of neurons in substantia nigra |
|
Definition
Parkinson Disease
(Basal Ganglia disorder > rigidity, resting tremor, bradykinesia) |
|
|
Term
Desquamated epithelium casts in sputum |
|
Definition
Curschmann Spirals
(Bronchial asthma
Can cause whorled mucous plugs) |
|
|
Term
Disarrayed granulosa cells in eosinphilic fluid |
|
Definition
Call-Exner bodies
(granulosa-theca cell tumor of the ovary) |
|
|
Term
Dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia |
|
Definition
Koilocytes
(HPV: predisposes to cervical cancer) |
|
|
Term
Enlarged cells with intranuclear inclusion bodies |
|
Definition
"Owl eye" appearance of CMV |
|
|
Term
Enlarged thyroid cells with ground-glass nuclei |
|
Definition
"Orphan Annie" eyes nuclei
(Papillary Carcinoma of the Thyroid) |
|
|
Term
Eosinophilic cytoplasmic inclusion in liver cell |
|
Definition
Mallory body
(Alcoholic liver disease) |
|
|
Term
Eosinophilic cytoplasmic inclusion in nerve cell |
|
Definition
Lewy body
(Parkinson Disease) |
|
|
Term
Eosinophilic globule in liver |
|
Definition
Councilman body
(Toxic or Viral Hepatitis
Yellow Fever) |
|
|
Term
Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar nerve cells |
|
Definition
|
|
Term
Extracellular amyloid deposition in gray matter of brain |
|
Definition
Senile Plaques (Alzheimer Disease) |
|
|
Term
Giant B-cells with bilobed nuclei with prominent inclusions ("owl's eye") |
|
Definition
Reed-Sternberg cells
(Hodgkin Lymphoma) |
|
|
Term
Glomerulus-like structure surrounding vessel in germ cells |
|
Definition
Schiller-Duval bodies
(Yolk Sac tumors) |
|
|
Term
"Hair on end" (crew-cut) appearance on x-ray |
|
Definition
B-thalassemia
Sickle Cell Anemia
(marrow expansion) |
|
|
Term
|
Definition
Choriocarcinoma
Hydatidiform Mole
(occurs with and without embryo)
Multiple Pregnancy |
|
|
Term
Heart nodules (Granulomatous) |
|
Definition
Aschoff bodies
(Rheumatic Fever) |
|
|
Term
|
Definition
Infectious mononucleosis
(EBV) |
|
|
Term
Hexagonal, double-pointed, needle-like crystals in bronchial secretions |
|
Definition
Bronchial Asthma
(Charcot-Leyden crystals: eosinophilic granules) |
|
|
Term
|
Definition
|
|
Term
Hilar lymphadenopathy
Peripheral granulomatous lesion in middle or lower lung lobes (can calcify) |
|
Definition
Ghon Complex
(primary TB: Mycobacterium bacilli) |
|
|
Term
"Honeycomb lung" on x-ray or CT |
|
Definition
Interstitial Pulmonary Fibrosis |
|
|
Term
Hypercoagulability
(leading to migrating DVTs and vasculitis) |
|
Definition
Trousseau Syndrome
(adenocarcinoma of pancreas or lung) |
|
|
Term
Hypersegmented neutrophils |
|
Definition
Megaloblastic anemia
B12 deficiency = neurologic symptoms
Folate deficiency = no neurologic symptoms |
|
|
Term
HTN
Hypokalemia
Metabolic acidosis |
|
Definition
|
|
Term
Hypochromic, microcytic anemia |
|
Definition
Iron deficiency anemia
Lead poisoning
Thalassemia
(fetal Hgb sometimes present) |
|
|
Term
Increased AFP in amniotic fluid/maternal serum |
|
Definition
Dating Error
Anencephaly
Spina Bifida
(neural tube defects) |
|
|
Term
Increased uric acid levels |
|
Definition
Gout
Lesch-Nyhan Syndrome
Tumor lysis syndrome
Loop and Thiazide diuretics |
|
|
Term
Intranuclear eosinophilic droplet-like bodies |
|
Definition
Cowdry type A bodies
(HSV
CMV) |
|
|
Term
Iron-containing nodules in alveolar septum |
|
Definition
Ferruginous bodies
(Asbestosis > increased chance of Mesothelioma) |
|
|
Term
Keratin pearls on a skin biopsy |
|
Definition
|
|
Term
Large lysosomal vesicles in phagocytes
Immunodeficiency |
|
Definition
Chediak-Higashi disease
(congenital failure of phagolysosome formation due to microtubule defect) |
|
|
Term
"Lead pipe" appearance of colon on barium enema x-ray |
|
Definition
Ulcerative Colitis
(loss of haustra) |
|
|
Term
Linear appearance of IgG deposition on glomerular basement membrane |
|
Definition
|
|
Term
|
Definition
Wilson Disease
(hepatolenticular degeneration) |
|
|
Term
"Lumpy bumpy" appearance of glomeruli on immunofluorescence |
|
Definition
Poststreptococcal glomerulonephritis
(immune complex deposition of IgG and C3b) |
|
|
Term
Lytic ("hole punched") bone lesions on x-ray |
|
Definition
|
|
Term
Mammary gland ("blue domed") cyst |
|
Definition
Fibrocystic change of the breast |
|
|
Term
Monoclonal antibody spike |
|
Definition
Multiple Myeloma (IgG or IgA)
Monoclonal Gammopathy of undetermined significance (MGUS, consequence of aging)
Waldenstrom (M protein = IgM) Macroglobulinemia
Primary Amyloidosis |
|
|
Term
Mucin-filled cell with peripheral nucleus |
|
Definition
"Signet ring"
(Gastric Carcinoma) |
|
|
Term
Necrotizing vasculitis (lungs)
Necrotizing Glomerulonephritis |
|
Definition
Granulomatosis with Polyangiitis (Wegner: PR3-ANCA/c-ANCA)
Goodpasture Syndrome (anti-basement membrane antibodies) |
|
|
Term
Needle-shaped, negatively birefringent crystals |
|
Definition
Gout
(monosodium urate crystals) |
|
|
Term
Nodular hyaline deposits in glomeruli |
|
Definition
Kimmelstiel-Wilson nodules
(Diabetic Nephropathy) |
|
|
Term
|
Definition
Sensitive = Staphylococcus epidermidis
Resistant = Staphylococcus saprophyticus |
|
|
Term
"Nutmeg" appearance of liver |
|
Definition
Chronic passive congestion of liver due to right heart failure |
|
|
Term
"Onion skin" periosteal reaction |
|
Definition
Ewing Sarcoma
(malignant round-cell tumor) |
|
|
Term
|
Definition
Sensitive = Streptococcus pneumoniae
Resistant = Viridans streptococci |
|
|
Term
Periosteum raised from bone > triangular area |
|
Definition
Codman triangle on x-ray
(Osteosarcoma
Ewing Sarcoma
Pyogenic osteomyelitis) |
|
|
Term
Podocyte fusion of "effacement" on electron microscopy |
|
Definition
Minimal Change Disease
(child with nephrotic syndrome) |
|
|
Term
Polished, "ivory-like" appearance of bone at cartilage erosion |
|
Definition
Eburnation
(osteoarthritis resulting in bony sclerosis) |
|
|
Term
Protein aggregates in neurons from hyperphosphorylation of tau protein |
|
Definition
Neurofibrillary tangles (Alzheimer's disease)
Pick bodies (Pick disease) |
|
|
Term
|
Definition
Meningiomas
Papillary Thyroid Carcinoma
Mesothelioma
Papillary Serous Carcinoma (Endometrium and Ovary) |
|
|
Term
Pseudopalisading tumor cells on brain biopsy |
|
Definition
|
|
Term
|
Definition
|
|
Term
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells |
|
Definition
Reinke Crystals
(Leydig cell tumor) |
|
|
Term
Renal epithelial casts in urine |
|
Definition
Acute toxic/viral renal injury |
|
|
Term
Rhomboid crystals, positively birefringent |
|
Definition
Pseudogout
(Calcium pyrophosphate dihydrate crystals) |
|
|
Term
|
Definition
|
|
Term
Ring-enhancing brain lesions in AIDS |
|
Definition
Toxoplasma gondii
CNS Lymphoma |
|
|
Term
Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ("starry sky" histology) |
|
Definition
Burkitt Lymphoma
(t[8;14] c-myc activations
Associated with EBV
"Black sky" made up of malignant cells) |
|
|
Term
Silver-staining spherical aggregation of tau proteins in neurons |
|
Definition
Pick bodies
(Pick disease - progressive dementia, changes in personality) |
|
|
Term
"Soap bubble" in femur or tibia on x-ray |
|
Definition
Giant cell tumor of bone (generally benign) |
|
|
Term
"Spikes" on basement membrane
"Dome-like" subepithelial deposits |
|
Definition
Membranous glomerulonephritis
(may progress to nephrotic syndrome) |
|
|
Term
|
Definition
Rouleaux formation
(High ESR
Multiple Myeloma) |
|
|
Term
Stippled vaginal epithelial cells |
|
Definition
"Clue Cells"
(Gardnerella vaginalis) |
|
|
Term
"Tennis racket"-shaped cytoplasmic organelles (EM) in Langerhans cells |
|
Definition
Birbeck Granules
(Langerhans Cell Histiocytosis or Histiocytosis X: eosinophilic granuloma) |
|
|
Term
Thrombi made of white/red layers |
|
Definition
Lines of Zahn
(arterial thrombus, layers of platelets/RBCs) |
|
|
Term
"Thumb sign" on lateral x-ray |
|
Definition
Epiglottitis
(Haemophilus influenzae) |
|
|
Term
Thyroid-like appearance of kidney |
|
Definition
Chronic bacterial pyelonephritis |
|
|
Term
"Tram-track" appearance of capillary loops of glomerular basement membranes on light microscopy |
|
Definition
Membranoproliferative glomerulonephritis |
|
|
Term
Triglyceride accumulation in liver cell vacuoles |
|
Definition
Fatty liver disease
(Alcoholic or Metabolic Syndrome) |
|
|
Term
"Waxy" casts with very low urine flow |
|
Definition
Chronic end-stage renal disease |
|
|
Term
|
Definition
|
|
Term
|
Definition
CLL
(almost always B-cell) |
|
|
Term
"Wire loop" glomerular capillary appearance on light microscopy |
|
Definition
|
|
Term
|
Definition
Xanthochromia
(Subarachnoid Hemorrhage) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Positive Predictive Value |
|
Definition
|
|
Term
Negative Predictive Value |
|
Definition
|
|
Term
Odds Ratio
(for Case-Control studies) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
1/absolute risk reduction |
|
|
Term
|
Definition
|
|
Term
Hardy-Weinberg Equilibrium |
|
Definition
p2 + 2pq + q2 = 1
p+q = 1 |
|
|
Term
|
Definition
amount of drug in the body
plasma drug concentration |
|
|
Term
|
Definition
|
|
Term
|
Definition
rate of elimination of drug
plasma drug concentration
or
Vd x Ke
(Ke = elimination constant) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
rate of O2 consumption
arterial O2 content - venous O2 content
or
SV x HR |
|
|
Term
|
Definition
CO x TPR
or
2/3 diastolic + 1/3 systolic |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Driving Pressure (delta P)
Flow (Q)
or
8n (viscosity) x length
pi x r4 |
|
|
Term
|
Definition
(Pc - Pi) - (pic - pii)
(out - in) - (in - out)
or
Jv = net fluid flow = (Kf)(Pnet) |
|
|
Term
|
Definition
|
|
Term
Glomerular Filtration Rate |
|
Definition
Uinulin x V
Pinulin
or
Kf[(PGC - PBS) - (piGC - piBS)] |
|
|
Term
Effective Renal Plasma Flow |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Henderson-Hasselbalch Equation
(for extracellular pH) |
|
Definition
pH = 6.1 + log [HCO3-]
0.03 x [PCO2] |
|
|
Term
|
Definition
PCO2 = 1.5 x [HCO3-] + 8 + 2 |
|
|
Term
|
Definition
|
|
Term
Pulmonary Vascular Resistance |
|
Definition
Ppulm artery - PL atrium
CO |
|
|
Term
|
Definition
|
|
Term
Absence seizures
(Treatment) |
|
Definition
|
|
Term
Acute Gout Attack
(Treatment) |
|
Definition
|
|
Term
Acute Promyelocytic Leukemia (M3)
(Treatment) |
|
Definition
|
|
Term
|
Definition
Methylphenidate
Amphetamines |
|
|
Term
Alcohol Use Disorder
(Treatment) |
|
Definition
AA +
Disulfiram,
Naltrexone, or
Acamprosate
A1-Anon for family |
|
|
Term
Alcohol Withdrawal
(Treatment) |
|
Definition
|
|
Term
|
Definition
|
|
Term
Anticoagulation during pregnancy
(Treatment) |
|
Definition
|
|
Term
Arrhythmia in damaged cardiac tissue
(Treatment) |
|
Definition
Class IB antiarrhythmics
(Lidocaine
Mexiletine
Tocainide) |
|
|
Term
B12 Deficiency
(Treatment) |
|
Definition
Vitamin B12 supplementation
(work up cause with Schilling test) |
|
|
Term
Benign prostatic Hyperplasia
(Treatment) |
|
Definition
|
|
Term
Bipolar Disorder
(Treatment) |
|
Definition
Lithium
Valproate
Carbamazepine
Lamotrigine
(mood stabilizers) |
|
|
Term
Breast cancer in postmenopausal woman
(Treatment) |
|
Definition
Aromatase inhibitor
(Anastrozole) |
|
|
Term
Buerger Disease
(Treatment) |
|
Definition
|
|
Term
Bilimia Nervosa
(Treatment) |
|
Definition
|
|
Term
Candida Albicans
(Treatment) |
|
Definition
Systemic = Amphotericin B
Oral Thrush = Nystatin
Vaginitis = Azoles |
|
|
Term
Carcinoid Syndrome
(Treatment) |
|
Definition
|
|
Term
Chlamydia trachomatis
(Treatment) |
|
Definition
Doxycycline
(+ Ceftriaxone for Gonorrhea coinfection)
Erytromycin eye drops
(prophylaxis in infants) |
|
|
Term
|
Definition
Probenecid (underexcretor)
Allopurinol (overproducer)
Febuxostat |
|
|
Term
Chronic Hepatitis
(Treatment) |
|
Definition
|
|
Term
Chronic Myelogenous Leukemia
(CML)
(Treatment) |
|
Definition
|
|
Term
Clostridium botulinum
(Treatment) |
|
Definition
|
|
Term
Clostridium difficile
(Treatment) |
|
Definition
Oral Metronidazole
If refractory, oral Vancomycin |
|
|
Term
Clostridium tetani
(Treatment) |
|
Definition
Antitoxin + Vaccine booster + Diazepam |
|
|
Term
|
Definition
|
|
Term
Crohn Disease
(Treatment) |
|
Definition
Corticosteroids
Infliximab
Methotrexate
Azathioprine |
|
|
Term
Crytoccocus neoformans
(Treatment) |
|
Definition
Fluconazole
(propylaxis in AIDS patients) |
|
|
Term
Cyclophosphamide-induced Hemorrhagic Cystitis
(Treatment) |
|
Definition
|
|
Term
|
Definition
|
|
Term
Diabetes Insipidus
(Treatment) |
|
Definition
Central = DDAVP
Nephrogenic:
Hydrochlorothiazide
Indomethacin
Amiloride |
|
|
Term
Diabetes Mellitus Type 1
(Treatment) |
|
Definition
Dietary intervention (low sugar) + Insulin |
|
|
Term
Diabetes Mellitus Type 2
(Treatment) |
|
Definition
Dietary intervention
Oral hypoglycemics
Insulin (if refractory) |
|
|
Term
Diabetic Ketoacidodid
(Treatment) |
|
Definition
|
|
Term
|
Definition
Vancomycin/Ampicillin + Aminoglycosides |
|
|
Term
Erectile Dysfunction
(Treatment) |
|
Definition
|
|
Term
ER+ Breast Cancer
(Treatment) |
|
Definition
|
|
Term
Ethylene Glycol/Methanol Intoxication
(Treatment) |
|
Definition
Fomepizole
(alcohol dehydrogenase inhibitor) |
|
|
Term
iHaemophilus influenzae (B)
(Treatment) |
|
Definition
|
|
Term
Generalized Anxiety Disorder
(Treatment) |
|
Definition
|
|
Term
Granulomatosis with Polyangiitis (Wegner)
(Treatment) |
|
Definition
Cyclophosphamide
Corticosteroids |
|
|
Term
Heparin Toxicity (acute)
(Treatment) |
|
Definition
|
|
Term
Her2/neu+ Breast Cancer
(Treatment) |
|
Definition
|
|
Term
Hyperaldosteronism
(Treatment) |
|
Definition
|
|
Term
Hypercholesterolemia
(Treatment) |
|
Definition
|
|
Term
Hypertriglyceridemia
(Treatment) |
|
Definition
|
|
Term
Immediate anticoagulation
(Treatment) |
|
Definition
|
|
Term
|
Definition
Leuprolide
GnRH (pulsatile)
Clomiphene |
|
|
Term
|
Definition
|
|
Term
Legionella pneumophila
(Treatment) |
|
Definition
|
|
Term
Long-term anticoagulation
(Treatment) |
|
Definition
|
|
Term
|
Definition
Chloroquine/mefloquine (for blood schizont)
Primaquine (for liver hypnozoite) |
|
|
Term
Malignant Hyperthermia
(Treatment) |
|
Definition
|
|
Term
Medial Abortion
(Treatment) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Multiple Sclerosis
(Treatment) |
|
Definition
B-interferon
Immunosuppression
Natalizumab |
|
|
Term
Mycobacterium tuberculosis
(Treatment) |
|
Definition
(RIPE)
Rifampin
INH
Pyrazinamide
Ethambutol |
|
|
Term
Neisseria gonorrhoeae
(Treatment) |
|
Definition
Ceftriaxone
(add Doxycycline to cover likely concurrent Chlamydia) |
|
|
Term
Neisseria meningitidis
(Treatment) |
|
Definition
Penicillin/Ceftriaxone
Rifampin (prophylaxis) |
|
|
Term
Neural Tube defect prevention
(Treatment) |
|
Definition
|
|
Term
Osteomalacia / Rickets
(Treatment) |
|
Definition
Vitamin D supplementation |
|
|
Term
|
Definition
Bisphosphonates
Calcium + Vitamin D supplementation |
|
|
Term
Patent Ductus Arteriosus
(Treatment) |
|
Definition
|
|
Term
Pheochromocytoma
(Treatment) |
|
Definition
a-antagonists
(Phenoxybenzamine) |
|
|
Term
Pneumocystic jirovecii
(Treatment) |
|
Definition
TMP-SMX
(prophylaxis in AIDS) |
|
|
Term
|
Definition
Bromocriptine
(dopamine agonist) |
|
|
Term
Prostate Cancer / Uterine Fibroids
(Treatment) |
|
Definition
Leuprolide
GnRH (continuous) |
|
|
Term
Prostate Carcinoma
(Treatment) |
|
Definition
|
|
Term
Pseudomonas aeruginosa
(Treatment) |
|
Definition
Antipseudomonal Penicillin + Aminoglycoside |
|
|
Term
Pulmonary Arterial HTN (idiopathic)
(Treatment) |
|
Definition
Sildenafil
Bosentan
Epoprostenol |
|
|
Term
Rickettsia rickettsii
(Treatment) |
|
Definition
Doxycycline
Chloramphenicol
(associated with aplastic anemia) |
|
|
Term
Ringworm inefctions
(Treatment) |
|
Definition
Terbinafine
Griseofulvin
Imidazole |
|
|
Term
Schizophrenia (negative symptoms)
(Treatment) |
|
Definition
5-HT2A antagonists
(2nd generation antipsychotics) |
|
|
Term
Schizophrenia (positive symptoms)
(Treatment) |
|
Definition
D2 receptor antagonists
(1st and 2nd generation antipsychotics) |
|
|
Term
|
Definition
Demeclocycline
Lithium
Vasopressin receptor antagonists |
|
|
Term
Sickle Cell Anemia
(Treatment) |
|
Definition
Hydroxyurea
(increased fetal Hgb) |
|
|
Term
Sporothrix schenkii
(Treatment) |
|
Definition
|
|
Term
Stable Angina
(Treatment) |
|
Definition
|
|
Term
Staphylococcus aureus
(Treatment) |
|
Definition
MSSA:
Nafcillin
Oxacillin
Dicloxacillin
(antistaphylococcal penicillins)
MRSA = Vancomycin |
|
|
Term
Streptococcus bovis
(Treatment) |
|
Definition
Penicillin prophylaxis
Evaluation for colon cancer if linked to endocarditis |
|
|
Term
Streptococcus pneumoniae
(Treatment) |
|
Definition
Systemic/Pneumonia = Penicillin/Cephalosporin
Meningitis = Vancomycin |
|
|
Term
Temporal Arteritis
(Treatment) |
|
Definition
|
|
Term
Tonic-Clonic Seizures
(Treatment) |
|
Definition
Phenytoin
Carbamazepine
Valproate |
|
|
Term
Toxoplasma gondii
(Treatment) |
|
Definition
Sulfadiazine + Pyrimethamine |
|
|
Term
Treponema pallidum
(Treatment) |
|
Definition
|
|
Term
Trichomonas vaginalis
(Treatment) |
|
Definition
Metronidazole
(patient AND partner) |
|
|
Term
Trigeminal neuralgia (tic douloureux)
(Treatment) |
|
Definition
|
|
Term
Ulcerative Colitis
(Treatment) |
|
Definition
5-ASA
Infliximab
Colectomy |
|
|
Term
UTI Prophylaxis
(Treatment) |
|
Definition
|
|
Term
Warfarin Toxicity
(Treatment) |
|
Definition
Acute = Fresh frozen plasma
Chronic = Vitamin K |
|
|
Term
Actinic (solar) keratosis |
|
Definition
Precursor to squamous cell carcinoma |
|
|
Term
Acute gastric ulcer associated with CNS injury |
|
Definition
Cushing ulcer
(increased intracranial pressure > vagal stimulation > gastric secretion) |
|
|
Term
Acute gastric ulcer associated with severe burns |
|
Definition
Curling ulcer
(greatly reduced plasma volume > sloughing of gastric mucosa) |
|
|
Term
Alternating areas of transmural inflammation and normal colon |
|
Definition
Skip lesions
(Crohn Disease) |
|
|
Term
|
Definition
|
|
Term
Aortic aneurysm, abdominal and descending aorta |
|
Definition
|
|
Term
|
Definition
Tertiary Syphilis (Syphilitic aortitis
Vasa Vasorum destruction |
|
|
Term
Aortic aneurysm, ascending |
|
Definition
Marfan syndrome
(idiopathic cystic medial degeneration) |
|
|
Term
Atrophy of mammillary bodies |
|
Definition
Wernicke encephalopathy
(Thiamine deficiency > ataxia, ophthalmoplegia, confusion) |
|
|
Term
Autosplenectomy
(fibrosis and shrinkage) |
|
Definition
Sickle Cell Anemia
(hemoglobin S) |
|
|
Term
Bacteria associated with gastritis, peptic ulcer disease, and stomach cancer |
|
Definition
|
|
Term
Bacterial meningitis
(adults and elderly) |
|
Definition
|
|
Term
Bacterial Meningitis
(newborns and kids) |
|
Definition
Newborns = GBS, E. coli
Kids = S. pneumo, N. meningitidis |
|
|
Term
|
Definition
Spitz nevus
(most common in 1st 2 decades) |
|
|
Term
Bleeding disorder with GpIb deficiency |
|
Definition
Bernard-Soulier Syndrome
(defect in platelet adhesion to von Willebrand factor) |
|
|
Term
|
Definition
Supratentorial
Metastasis > Astrocytoma (GBM) > Meningioma > Schwannoma |
|
|
Term
|
Definition
Infratentorial:
Medulloblastoma (cerebellum)
Supratentorial:
Craniopharyngioma |
|
|
Term
|
Definition
Infiltrating ductal carcinoma |
|
|
Term
|
Definition
Fibrocystic change
Carcinoma (postmenopausal) |
|
|
Term
|
Definition
|
|
Term
Cardiac Primary tumor (kids) |
|
Definition
Rhabdomyoma
(seen with tuberous sclerosis0 |
|
|
Term
Cardiac manifestation of lupus |
|
Definition
Libman-Sacks endocarditis
(nonbacterial, affects both sides of Mitral valve) |
|
|
Term
Cerebellar tonsillar herniation |
|
Definition
|
|
Term
|
Definition
Atrial fibrillation
(associated with high risk of emboli) |
|
|
Term
Chronic atrophic gastritis
(autoimmune) |
|
Definition
Predisposition to gastric carcinoma
(can also cause Pernicious Anemia) |
|
|
Term
Clear cell adenocarcinoma of the vagina |
|
Definition
|
|
Term
|
Definition
Osteoporosis
Type 1 = postmenopausal woman
Type 2 = elderly man or woman |
|
|
Term
Congenital Adrenal Hyperplasia + Hypotension |
|
Definition
21-hydroxylase deficiency |
|
|
Term
Congenital Cardiac anomaly |
|
Definition
|
|
Term
Congenital conjugated hyperbilirubinemia
(black liver) |
|
Definition
Dubin-Johnson syndrome
(inability of hepatocytes to secrete conjugated bilirubin into bile) |
|
|
Term
Constrictive pericarditis |
|
Definition
Developing world = TB
Developed world = SLE |
|
|
Term
Coronary artery involved in thrombosis |
|
Definition
|
|
Term
|
Definition
Iodine deficiency
Hypothyroidism |
|
|
Term
|
Definition
Leiomyoma
(estrogen dependent, not precancerous) |
|
|
Term
|
Definition
Hemangioma
(usually regresses spontaneously by childhood) |
|
|
Term
Tumor of the adrenal medulla
(adults) |
|
Definition
Pheochromocytoma
(usually benign) |
|
|
Term
Tumor of the adrenal medulla
(kids) |
|
Definition
Neuroblastoma
(malignant) |
|
|
Term
|
Definition
Nodular sclerosis
(vs. Mixed cellularity, Lymphocytic predominance, Lymphocytic depletion) |
|
|
Term
|
Definition
|
|
Term
|
Definition
E. coli
Staph. saprophyticus (young women) |
|
|
Term
Viral encephalitis affecting temporal lobe |
|
Definition
|
|
Term
Vitamin deficiency
(U.S.) |
|
Definition
Folate
(pregnant women are at high risk; body stores only 3-4 month supply; prevents neural tube defects) |
|
|
Term
Ovarian tumor
(malignant) |
|
Definition
Serous Cystadenocarcinoma |
|
|
Term
|
Definition
|
|
Term
|
Definition
Adults = Alcohol
Kids = Cystic fibrosis |
|
|
Term
Patient with ALL/CLL/AML/CML |
|
Definition
ALL = child
CLL = adult > 60
AML = adult ~65
CML = adult 30-60 |
|
|
Term
Pelvic inflammatory disease |
|
Definition
Chlamydia trachomatis
N. gonorrhoeae |
|
|
Term
Philadelphia chromosome t(9;22) (bcr-abl) |
|
Definition
|
|
Term
|
Definition
Prolactinoma
Somatotropic acidophilic adenoma |
|
|
Term
|
Definition
|
|
Term
Primary bone tumor
(adults) |
|
Definition
|
|
Term
Primary hyperaldosteronism |
|
Definition
Adenoma of adrenal cortex |
|
|
Term
Primary hyperparathyroidism |
|
Definition
Adenoma
Hyperplasia
Carcinoma |
|
|
Term
|
Definition
Hepatocellular carcinoma
(Chronic hepatitis, Cirrhosis, Hemochromatosis, a1-antitrypsin deficiency) |
|
|
Term
|
Definition
|
|
Term
Recurrent inflammation/thrombosis of medium/small vessels in extremeties |
|
Definition
Buerger disease
(strongly associated with tobacco) |
|
|
Term
|
Definition
Renal cell carcinoma
Associated with VHL and cigarette smoking
Paraneoplastic syndromes:
Renin
ACTH
PTH
EPO |
|
|
Term
Right heart failure due to pulmonary cause |
|
Definition
|
|
Term
S3
(protodiastolic gallop) |
|
Definition
Increased ventricular filling
Causes:
Left-to-right shunt
Mitral regurgitation
LV failure (CHF) |
|
|
Term
|
Definition
Stiff/hypertrophic ventricle
Causes:
Aortic stenosis
Restrictive cardiomyopathy |
|
|
Term
Secondary Hyperparathyroidism |
|
Definition
Hypocalcemia of chronic kidney disease |
|
|
Term
Sexually transmitted disease |
|
Definition
Chlamydia
(usually coinfected with gonorrhea) |
|
|
Term
|
Definition
Small cell carcinoma of the lung |
|
|
Term
|
Definition
|
|
Term
|
Definition
Abdominal aorta > Coronary artery > Popliteal artery > Carotid artery |
|
|
Term
|
Definition
|
|
Term
Stomach ulcerations and high gastrin levels |
|
Definition
Zollinger-Ellison syndrome
(gastrinoma of duodenum or pancreas) |
|
|
Term
|
Definition
Follicular lymphomas (bcl-2 activation) |
|
|
Term
|
Definition
Burkitt Lymphoma
(c-myc activation) |
|
|
Term
|
Definition
Philadelphia chromosome > CML
(bcr-abl fusion) |
|
|
Term
|
Definition
Risk of ipsilateral blindness due to thrombosis of ophthalmic artery
Polymyalgia rheumatica |
|
|
Term
|
Definition
Seminom
(malignant, radiosensitive) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Iatrogenic Cushing (corticosteroid therapy)
Adrenocortical adenoma (secretes excess cortisol)
ACTH-secreting pituitary adenoma
Paraneoplastic Cushing (ACTH secretion by tumors) |
|
|
Term
Cyanosis
(early; less common) |
|
Definition
Tetralogy of Fallot
Transposition of Great vessels
Truncus Arteriosus |
|
|
Term
Cyanosis
(late; more common) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Alzheimer disease
Multiple infarcts |
|
|
Term
Demyelinating disease in young women |
|
Definition
|
|
Term
|
Definition
Severe sepsis
Obstetric complications
Cancer
Burns
Trauma
Major surgery |
|
|
Term
|
Definition
|
|
Term
|
Definition
Zenker diverticulum
(diagnosed by barium swallow) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Worldwide = Squamous cellc arcinoma
U.S. = Adenocarcinoma |
|
|
Term
Food Poisoning
(exotoxin mediated) |
|
Definition
|
|
Term
Glomerulonephritis
(adults) |
|
Definition
Berger disease
(IgA Nephropathy) |
|
|
Term
|
Definition
U.S. = Endometrial carcinoma
Worldwide = Cervical carcinoma |
|
|
Term
|
Definition
|
|
Term
Heart valve in bacterial endocarditis |
|
Definition
Mitral > Aortic (Rheumatic Fever), Tricuspid (IV drug abuse) |
|
|
Term
Helminth infection
(U.S.) |
|
Definition
Enterobius vermicularis
Ascaris lumbricoides |
|
|
Term
|
Definition
RUpture of Middle Meningeal artery
(Trauma; lentiform shaped) |
|
|
Term
|
Definition
Rupture of bridging veins
(crescent shaped) |
|
|
Term
|
Definition
Multiple blood transfusions
Hereditary HFE mutation
(Can cause:
CHF
"Bronze diabetes"
increased risk of hepatocellular carcinoma) |
|
|
Term
|
Definition
Cirrhotic liver
(associated with Hepatitic B and C and Alcoholism) |
|
|
Term
Hereditary Bleeding disorder |
|
Definition
|
|
Term
Hereditary harmless jaundice |
|
Definition
Gilbert Syndrome
(benign congenital unconjugated hyperbilirubinemia) |
|
|
Term
|
Definition
Ankylosing Spondylitis
Reactive Arthritis
Ulcerative Colitis
Psoriatic Arthritis |
|
|
Term
|
Definition
|
|
Term
|
Definition
VSD
Tricuspid Regurgitation
Mitral Regurgitation |
|
|
Term
Hypercoagulability
Endothelial damage
Blood Stasis |
|
Definition
Virchow's Triad
(causes venous thrombosis) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Accidental excision during thyroidectomy |
|
|
Term
|
Definition
Pituitary adenoma
(usually benign tumor) |
|
|
Term
Infection secondary to blood transfusion |
|
Definition
|
|
Term
Infections in chronic granulomatous disease |
|
Definition
(Catalase +)
Staph. aureus
E. coli
Aspergillus |
|
|
Term
|
Definition
Down Syndrome
Fragile X Syndrome |
|
|
Term
|
Definition
Calcium = radiopaque
Struvite (ammonium) = radiopaque
(formed by urease + organisms like Proteus vulgaris or Staph)
Uric acid = radiolucent |
|
|
Term
Late cyanotic shunt
(uncorrected left to right becomes right to left) |
|
Definition
Eisenmenger syndrome
Causes:
ASD
VSD
PDA
Results in pulmonary HTN and polycythemia |
|
|
Term
|
Definition
|
|
Term
Lysosomal storage disease |
|
Definition
|
|
Term
|
Definition
|
|
Term
Malignancy associated with noninfectious fever |
|
Definition
|
|
Term
|
Definition
ALL
Medulloblastoma (cerebellum) |
|
|
Term
|
Definition
Prostate / Breast > Lung > Thyroid
(+ Kidney)
BLT with a Kosher Pickle |
|
|
Term
|
Definition
Lung > Breast > Genitourinary > Melanoma > GI |
|
|
Term
|
Definition
Colon >> Stomach / Pancreas |
|
|
Term
Mitochondrial Inheritance |
|
Definition
Disease occurs in both males and females, inherited through females only |
|
|
Term
|
Definition
|
|
Term
Mixed (UMN and LMN) motor neuron disease |
|
Definition
Amyotrophic lateral sclerosis |
|
|
Term
|
Definition
|
|
Term
Nephrotic Syndrome
(adults) |
|
Definition
Focal Segmental Glomerulosclerosis |
|
|
Term
Nephrotic Syndrome
(kids) |
|
Definition
|
|
Term
|
Definition
Kallmann syndrome
(Hypogonadotropic hypogonadism + Anosmia) |
|
|
Term
|
Definition
Klebsiella
E. coli
Pseudomonas aeruginosa |
|
|
Term
Obstruction of male urinary tract |
|
Definition
|
|
Term
|
Definition
|
|
Term
Opportunistic infection in AIDS |
|
Definition
Pneumocystic jirovecii pneumonia |
|
|
Term
|
Definition
|
|
Term
Osteomyelitis in Sickle CEll Disease |
|
Definition
|
|
Term
eomyelitis with IV drug use |
|
Definition
|
|
Term
Ovarian metastasis from gastric carcinoma or breast cancer |
|
Definition
Krukenberg tumor
(mucin-secreting signet-ring cells) |
|
|
Term
Ovarian tumor
(benign, bilateral) |
|
Definition
|
|