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Rad Pathology
Chapter 4-Skeletal System
29
Medical
Professional
05/13/2009

Additional Medical Flashcards

 


 

Cards

Term

[image]

Characteristics of vertebrae on both sides of a major division of the spine

 

Most common: ____

Findings are incidental

[image]

Definition

Transitional Vertebra

Congenital Disease

 

L5-S1

 

can also have ribs off of C-7 can also have at T-12,

L-1,L-5,and S-1

Term

[image]

 

Posterior defect of the spinal canal resulting from failure of the posterior elements to fuse properly mild insignificant form is _____, in which there is a splitting of thebony neural canal at the L5-S1 Level.

Definition

Spina Bifida

(spina bifida occulta)

Term

[image]

 

Rare hereditary bone dysplasia

-Faulty bone (development) reabsorbtion

-Prevents bone marrow formation

-image may looked blurred

 

*AKA:_____

symetric generalized ____in bone density

Technique change?

Definition

Osteopetrosis

Congenital

AKA Marble Bone Disease

 

increase

 

increase technique

Term

[image]

 

Inherited disorderof connective tissue

-Lack of osteoblastic activity & inadequate bone collagen

-blue color of white sclera of the eye

AKA: _____

Appearance:

-Multiple Fractures

-Severe Osteoporosis

-Extensive callus formation

Technique?

 

Definition

Osteogenesis Imperfecta

 

Congenital Disease of Bone

 

AKA: Brittle bone disease

 

Lower Technique

Term

[image]

 

  • Def: Abnormal conversion of cartilage into bone

-most common form of dwarfism

  • Appearance

-Progressive narrowing of interpedicular distance from above downward

-Scalloping of posterior margins of lumbar

-Long bones appear short and thick

no taller than 4ft.

Definition

Achondroplasia

Congenital disease of bone

Term

[image]

 

Def: Incomplete ____ formation with tendons and ligaments being affected

-Due to ____ hormone levels or ____ of fetus in utero

Images:  AP & bilateral _____ (frog leg) views

  • Demonstrates dislocation _____ and _____

Usually infants

Definition

Congenital Hip Dysplasia

acetabulum

increase

size

cleaves

superiorly

posteriorly

 

Term

[image]

 

Def: Inflammatory arthritis of the small joints of the hands and feet

-Chronic systemic disease of unknown cause

  • Symmetric involvement of multiple joints

-Crippling deformity

  • Affects women average onset is __ years
  • Appearance:

-Early signs: soft tissue swelling; osteoporosis

-Later: decrease in joint space(smooth narrowing), eroded ends of bones and subluxation(partial dislocation)

enzymes attack bone

Definition

Rheumatoid Arthritis

Inflammatory/ Infectious Disease

Term

[image]

 

Def: Begins in the SI joints

-bilateral(both sides) symmetrical involvement

-Progressive from the lumbar upward

AKA ____

Appearance: ______

-blurring of articular margins & patchy sclerosis progressing to narrowing of the joint space which leads to bony ankylosis

-severe vertebral fusion

-poker spine

Definition

Ankylosing Spondylitis

Inflammatory/Infectious disease

 

rheumatoid spondylitis

 

bamboo spine

Term

[image]

 

Def: characterized by arthritis, urethritis, and conjunctivitis

-Occurs after certain types of venereal or GI infections

-AKA: _______

-Affects young adult men

  • Involves SI joints,heel, and toes

affects feet more than hands

-Changes mimic rheumatoid arthritis

Definition

Reiter Syndrome

AKA Reactive arthritis

 

Term

[image]

 

Def: Loss of joint cartilage and new bone formation

AKA ____

Affects weight bearing joints (spine,hips,knee,ankles)

  • Appearance

-Narrowing of joint space(irregular)

*-Osteophytes(bone spur)

Definition

Osteoarthritis

AKA Degenerative Joint Disease


Term

[image]

 

Def: Inflammation of the bursea

-due to repeated physical activity,trauma,rheumatoid arthritis,gout or infection

-Appearance: calcifications in adjacent tendons(calcific tendinitis)

Definition
Bursitis
Term

[image]

 

Def: Generalized or localized deficiency of bone matrix

-osteoclast/osteoblastic activity

Acelerated resorption of bone

Decreased bone formation

-Loss of bone mass and density

Porous, brittle & prone to fx

Most evident, compression & hip fx

 

AKA: ______

Technique?

Definition

Osteoporosis

 

lower technique

 

Picture Frame Pattern

 


Term

[image]

 

Def: Insufficient mineralization of the adult skeleton

 

-Lack of calcium and phosphate

Deficiency of Vitamin D

Pregnancy

Kidney failure/renal disease

 

Appearance

-Softening of bones

-Cortical borders appear indistinct(opposite of osteoporosis)

-inward bending of acetabular wall

Definition
Osteomalacia
Term

Def. systemic disease of infancy & childhood

-Deficiency of Vitamin D in the diet or lack of exposure to sunshine

-Deficiency in the calcification of bones

AKA______

 Most common  ______

-Develops 6mo to a year

 

Radiographic changes best seen- ___,___,___, and ____ areas (fasting growing areas of bone)

  • ______ and ______ metaphysis in long bones

 

Definition

Ricket's/ AKA Infantile Osteomalacia

 

premature infants

ribs,tibia,humerus and wrist

cupped and frayed

Term

Def. Disorder of the metabolism of purine

- Increase in the blood level of ____ ____

-Deposits of ________ in the joints, cartilage & kidneys.

  • Primary/Secondary gout
  • *Most affects the ______

-Appearance

Changes develop late in disease & after repeated attacks

-Rat Bite

clump of uric acid at particular jt. is _______

jt. space narrowing

Definition

Gouty Arthritis

uric acid

uric acid inthe joints

1st MTP joint

 

gouty tophi

Term

Def. Old bone starts breaking down faster thannew bone can be built resulting in weak & soft bones leading to fx.

 

AKA______

 

-Most common middle aged med

 

____ area is initial site, femurs,skull ,tibia, vertebrae, clavicles & ribs

  • Appearance

-Skull- radiolucency initially(destructive osteolytic stage) with sclerosis & cortical thickening (mottled, ______Reparative osteoblastic stage)

-Spine- enlargement of vertebrae

Definition

Paget's Disease(Osteitis deformans) Metabolic bone disease

Pelvic

cotton-wool

 

Term

Def. Bone death from inadequate blood supply to the femoral head following trauma,injury or even can be idiopathic.

-Usually unilateral

-affects young boys around the age of 5 to 10 years

  • clinical signs-limp with little or no pain

Appearance

-images demonstrate fagmented and flattened femoral head

Definition
Legg-Calve Perthes
Term

Def. acute or chronic inflammation of bone & bone marrow caused by a pathogenic microorganism

 

-Spreads via bloodstream

bloodstream, adjacent infection or direct introduction(surgery)

 

-Begins as an abscess with pus that spreads to the surface of the bone and to adjacent areas

 

-affects long bones(children) & vertebra+pelvis(pelvis)

 

-NM/xrays

 

Appearance

ragged moth eaten

Definition
Osteomyelitis Inflammatory Disorders
Term

Def. Proliferation of fibrous tissue within the medullary cavity

-Gradually expands and weakens the bone

Loss of trabecular markings

Widening of the bone

-Single bone or bones of one extremity or throughout entire skeleton (in children

Long bones femur and tib, ribs & facial bones

prone to fx.

 

Appearance

-well defined radiolucent areas

completely radiolucent

ground glass density

multiocular

Definition
Fibrous Dysplasia Metabolic bone disease
Term

Def. Benign projection of bone with a cartilaginous cap(can become malignant)

-Arises during childhood or teen years

-occurs in the epiphyseal plate and grows laterally

-Cortex blends with normal bone & grows parallel and away from nearest joint

-Cap may become thick & calcified-malignancy

Osteosarcoma or chondrosarcoma

Definition

Osteochondroma/Exostosis

Benign Bone Tumors

Term

Def: slow growing benign tumor arising in medullary cavity

-Destroys normal bone

-prone to fx

  • Affects small bones of _______

children and young adults

  • Often multiple lesions
  • Appearance: Radiolucent lesion with small calcifications
Definition

Enchondroma

hands and feet

Term

Def: rare, aggressive benign tumor appearing as destructive lesions next to the joint

-Occurs mostly in the epiphysis; does not involve the joint

 

Affects adults aged 20 to 40 years

*AKA: ______

  • Appearance:as the tumor expands toward the shaft-demonstrates multiple large bubbles separated by thin strips of bone
Definition

Osteoclastomas

Benign bone tumors

 

Giant cell tumor

Term

Def: tumor of teenagers or young adults found in the femur or tibia

 

-Originate from _____ cells

-Tumor is a small, round or oval lucent center (nidus) surrounded by a large, dense sclerotic area of cortical thickening

 

-Pain is worse at night

Relieve with aspirin

Definition

Osteoid Osteoma(benign bone tumors)

 

osteoblasitic cells

Term

AKA_____

 

Def. A true fluid filled cyst with a wall of fibrous tissue

-Occurs in proximal humerus or femur

  • Appearance:

-Expansile lucent lesion that is sharply demarcated(outlined) from adjacent bone

-Thin rim of sclerosis around it

-Oval configuration

-Pain

Definition

Simple Bone Cyst

(unicameral)

Term

Def: consists of osteoblasts producing spicules of calcified bone

 

*Most frequently diagnosed bone cancer

 

-Tend to arise in those 10-25 years of age

  • Paget's disease predispose

AKA ______

 

  • Develop pulmonary metastases
  • Generally occurs in the end of long bones Especially the ____

Appearance: Mixed destructive & sclerotic lesion with soft tissue mass

-_____ pattern

-Elevation of the periosteum at periphery of lesion with new bone formation

Definition

Osteogenic Sarcoma

AKA: Osteosarcoma

 

Knee

 

Sunburst

Term

Def: pre-existing cartilaginous lesion or anew

-Osteochondroma/ enchondrom

-Develop later 35 to 60 yearsold

-Grows more slowly

-Metastasizes later

 

  • Appearance

-Contains calcifications within mass

-Destroys bone

Definition

Chondrosarcoma

Malignant bone tumors

Malignant cap

Term

Def: Primary tumor arising in bone marrow of long bones

-Pediatric bone cancer

-Extremely malignant, spreads to soft tissue

 

Rare after 30

 

  • Appearance

-Area of bone destruction involving a large central portion of shaft

-Fusiform layered periosteal reaction parallel to shaft (_____________)

Definition

Ewing Sarcoma

Malignant bone tumor

 

Onionskin appearance

Term

Def: Widespread malignancy of plasma cells that infiltrate bone producing multiple osteolytic lesions throughout

 

  • Affects those 40-70years of age
  • Appearance

-_________ on lateral skull

-Lesions tend to be more discrete and uniform in size than Mets

Definition

Multiple Myeloma

Swiss cheese

-May have kidney issues

-Extremely malignant

 

 

Term

Def: Most common malignant bone tumors

 

-Spread by means of bloodstream or lymphatic vessels or by direct extension

-Most common primary tumors:breast, lung, prostate, kidney and thyroid

 

-Favorite sites: spine, pelvis, ribs, skull, humerus and femur

Definition
Bone Metastases (METs)
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