Term
| IL-5 (bronchoconstriction) |
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Definition
| Release eosinophils from bone marrow |
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Term
| Asthma classification (1-4) |
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Definition
1 = mild >80
2 = mild persistant > 80
3 = moderate persist 60-80
4 = severe <60 |
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Term
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Definition
Fast acting inhaled B-adrenergic AGONIST
(increases cAMP--> increased PKA --> opens K and decreases Ca)
Side effects: INCREASED HR, TREMOR, ARRYTHMIA, VASODILATION
AVOID PPL HEART FAILURE |
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Term
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Definition
Both a fast acting inhaled and oral slow release B AGONIST
AVOID HEART FAILURE --> INCREASED HR, Vasodilation, tremor, arrythmia |
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Term
|
Definition
oral slow release B AGONIST
AVOID HEART FAILURE --> INCREASED HR, Vasodilation, tremor, arrythmia |
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Term
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Definition
Long term acting inhaled B-agonist
AVOID HEART FAILURE --> INCREASED HR, Vasodilation, tremor, arrythmia
DONT USE AS MONOTHERAPY |
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Term
|
Definition
Long term acting inhaled B-agonist
AVOID HEART FAILURE --> INCREASED HR, Vasodilation, tremor, arrythmia
DONT USE AS MONOTHERAPY |
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Term
|
Definition
Fast acting B-agonist (R ISOMER ALBUTEROL)
MUST USE NEBULIZER... Less side effects but not more effective |
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Term
|
Definition
anti-muscarinic M3 agonist prevents bronchoconstriction.
dry mouth, blurred vision, glaucoma, urinary retention |
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Term
|
Definition
anti-muscarinic M3 agonist prevents bronchoconstriction... DRY
dry mouth, blurred vision, glaucoma, urinary retention |
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Term
| INHALED STEROIDS (pulmonary) |
|
Definition
Beclomethasone
Budesonide
Flunisolide
Triamcinolone
Fluticasone
Mometasone
hoarseness, thrush, osteoporosis, adrenal suppression |
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Term
| System Corticosteroids (pulmonary) |
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Definition
IV hydrocortisone
prednisolone
increased appetite, fluid retention, susceptibility to infections,
fluid retention, cataracts, inhibition of hypothalamus/pituitary
axis |
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Term
|
Definition
Mast cell degranulation inhibitor
-inhibits airway nerves, degranulation mast cells, eosinophils
PROPHYLAXIS ONLY VIA DESENSITIZATION
joint swelling, laryngeal edema, headache, rash, nausea |
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Term
|
Definition
Mast cell degranulation inhibitor
-inhibits airway nerves, degranulation mast cells, eosinophils
PROPHYLAXIS ONLY VIA DESENSITIZATION
joint swelling, laryngeal edema, headache, rash, nausea |
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Term
|
Definition
anti-IgE (Free not one already bound receptor)
increased malignancies, anaphylaxis |
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Term
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Definition
lieukotriene receptor antagonist
prophylactic
abnormal liver function test, rash, nausea, vomiting, headache
MAY INTERACT WARFARIN |
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Term
|
Definition
Liekotriene receptor antagonist prophylactic
abnormal liver function test, rash, nausea, vomiting, headache
PEDIATRIC APPROVED
may cause Churg-Strauss syndrome eosinophilic pneumonia |
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Term
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Definition
5'Lipoxygenase inhibitor (lieukotriene synthesis)
acute liver disease, decreases clearance of warfarin and theophylline |
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Term
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Definition
(B-agonists and leukotriene modifier)
Similar to caffiene
smooth muscle relaxant, cns stimulant, cardiovascular stimulant (decrease peripheral resist)
1) Blocks Adenosine Receptors
2)Activates histone deacetylases (HDACs
3)Phosphodiesterase inhibitor
oral/parenteral administration: anxiety, fear, panic, fatal intoxication if
administered too fast |
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