Term
Divisions of the Respiratory System |
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Definition
1) Upper Airway 2) Lower Airway 3) Terminal Alveoli |
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Term
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Definition
Nasal cavities Sinuses Pharynx Tonsils Larynx |
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Term
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Definition
Conducting Airway: Trachea Bronchi Non-respiratory Bronchioles) |
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Term
Parts of the Terminal Alveoli |
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Definition
Respiratory Bronchioles Alveolar Ducts Alveolar Sacs |
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Term
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Definition
There are 26 generations.
The first 16 are purely conducting
Next are transitional airways
24th gen: Final Respiratory zone |
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Term
Classification of Pulmonary Disease |
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Definition
* Acute or Chronic
* Obstructive or Restrictive - tend to be chronic / incurable
* Infectious or Non-infectious - more often acute |
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Term
Signs and Symptoms of Pulmonary Disease |
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Definition
Cough Dyspnea Orthopnea Pleuritic Pain Cyanosis Clubbing Altered Breathing Patterns Tachypnea Abnormal chest wall shape Abnormal sputum Using accessory mm. of breathing Nasal Flaring Hemoptysis DOE - Dyspnea on exertion SOB |
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Term
Common Sites for referred Pulmonary Pain |
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Definition
Chest Ribs UT Shoulder-may radiate along medial arm T/S |
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Term
Characteristics of Pulmonary Disease Pain |
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Definition
May mimic MS pain in referral sites
Increases with Inspiratory Movements |
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Term
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Definition
Parietal Pleura is very sensitive to pain
Visceral Pleura is not sensitive to pain |
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Term
Conditions Caused by Pulmonary Disease |
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Definition
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Term
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Definition
Deficient oxygenation of arterial blood
Can lead to hypoxia |
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Term
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Definition
Diminished availability of O2 to body tissues |
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Term
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Definition
Respiratory alterations V/Q mismatch Decreased O2 Content Hypoventilation Alveolocapillary diffusion abnormality Pulmonary Shunting |
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Term
Signs and symptoms of Hypoxemia for PaO2 80-100 |
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Definition
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Term
Signs and symptoms of Hypoxemia for PaO2 60-80 |
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Definition
PaO2 Signs and Symptoms 60-80
Tachycardia DOE possibly-respiratory distress |
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Term
Signs and symptoms of Hypoxemia for PaO2 50-60 |
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Definition
malaise
light
headedness
nausea
vertigo
impaired judgement |
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Term
Signs and symptoms of Hypoxemia for PaO2 35-50 |
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Definition
marked confusion
cardiac dysrrhythmias
labored respiration |
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Term
Signs and symptoms of Hypoxemia for PaO2 25-35 |
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Definition
cardiac arrest
decreased renal blood flow
decreased urine output
lactic acidosis
lethargy
LOC |
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Term
Signs and symptoms of Hypoxemia for PaO2 <25 |
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Definition
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Term
Pulmonary Edema *Emergency condition* Definition |
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Definition
Accumulation of fluid in the tissues and air spaces of the lungs
Most commonly caused by heart disease, LVF, but also a complication of pulmonary disease |
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Term
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Definition
Inflammation affecting the parenchyma of the lungs
Can be:
Lobar p. Bronchopneumonia |
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Term
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Definition
Bacterial infection Viral infection - can be more serous Inhalation or aspiration of particulate etc. |
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Term
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Definition
Bronchitis Smoking immunodeficiency intubation COPD Chronic Renal Failure Chemotherapy Bed Rest Impaired cough reflex Dysphagia i |
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Term
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Definition
Pleuritic chest pain Productive Cough with rust or green sputum Dyspnea Tachypnea Fatigue Fever Generalized aches |
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Term
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Definition
Sputum Cultures Gram Stain Chest Films Lung Sounds Chest Percussion Urine test |
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Term
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Definition
Antibiotic Therapy Chest PT Rest Fluids |
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Term
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Definition
Recommended for
Over 65 Chronic disorders of the lungs Heart Liver Kidney and HIV or poorly controlled DM |
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Term
Pneumocystis Carinii Pneumonia (PCP) |
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Definition
Parasitic Infection-AIDS First indicator of AIDS in 60% of cases Also seen in: Transplants Chemo for lymphoma or leukemia Steroid Therapy in Malnutrition |
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Term
Pneumocystis Carinii Pneumonia (PCP)
Signs |
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Definition
Impaired Gas Exchange Fever Dyspnea Weight Loss Tachypnea |
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Term
Pneumocystis Carinii Pneumonia (PCP)
Interventions |
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Definition
Universal Precautions Breathing Exercises Energy Conservation |
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Term
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Definition
Infectious, inflammatory systemic disease that affects the lungs.
May disseminate to involve lymph nodes and other organs |
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Term
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Definition
Cause: Inhalation of infected airborne particles Infection with mycobacterium tuberculosis characterized by granulomas*, caseous necrosis, and cavity formation
(A granuloma is a small area of inflammation in tissue due to injury, such as from an infection. Granulomas most often occur in the lungs but can occur in other parts of the body as well. They typically cause no signs or symptoms and are found incidentally on a chest X-ray done for some other reason. Although granulomas are noncancerous (benign), they may resemble cancer on an X-ray.-Source www.mayoclinic.com) |
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Term
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Definition
primary infection involves middle or lower lung area and spreads to bronchopulmonary lymph nodes and then travels to the bloodstream |
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Term
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Definition
Elderly Poor health <5 years old Close quarters inadequate ventilation HIV |
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Term
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Definition
Appear late-usually after one year productive cough wt loss fever night sweats fatigue anorexia pulmonary infections lung atelectasis - collapse of a lung segment |
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Term
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Definition
skin test (Mantoux) chest xray culture of sputum bronchoscopy |
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Term
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Definition
combination drugs-rifampin, isoniazid etc. prevent transmission, need to be taken for 6-9 months |
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Term
Acute Bronchitis
Definition and Cause |
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Definition
Def: Inflammation of trachea and bronchi-Lasts for about 1-3 weeks
Cause: Chemicals, viral infections |
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Term
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Definition
cough chest pain constitutional sxs
Can lead to pneumonia |
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Term
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Definition
Refers to several disorders including:
Obstructive Bronchitis Emphysema Asthma |
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Term
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Definition
blood gas analysis sputum culture skin testing xray PFTs= Pulmonary Function Test |
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Term
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Definition
Improve PaO2 Decrease CO2 retention Prevent resp infection |
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Term
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Definition
Pharm management: bronchodilators mucolytics steroids antibiotics mast cell stabilizers oxygen vaccination against flu Pulmonary hygiene Bullectomy-Removal of non-funct. alveoli Chest PT |
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Term
Chronic Obstructive Bronchitis
Def and Cause |
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Definition
Productive cough lasting 3 mos. For two consecutive years, dec FEV1/FVC
Causative agent: smoking |
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Term
Chronic Obstructive Bronchitis
Signs |
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Definition
Cough with mucous Cyanosis Prolonged expiration Recurrent infection SOB Hypoxemia Retention of C02 Accessory breathing muscles hypertrophy of mucous producing cells air trapping *forced expiration tends to produce collapse of tissue |
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Term
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Definition
Obstructive Lung disease (3 types) that causes destruction of airways due to changes in lung tissue rather than mucous |
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Term
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Definition
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Term
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Definition
dyspnea tachypnea with prolonged expiration wasting appearance leaning forward with arms braced on knees to assist breathing |
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Term
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Definition
*Inflammation of airways causing bronchospasm with SOB and wheezing
*Reversible obstructive lung disease caused by increased reaction of the A/W to various stimuli |
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Term
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Definition
Release of inflammatory mediators (leukotrienes) produces:
bronchial smooth muscle spasm vascular congestion edema increased mucus production impaired mucociliary function --eosinophil infiltration Airway spasm trapping air ventilation/perfusion mismatch hypoxemia |
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Term
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Definition
first-sensation of chest constriction inspiratory/expiratory wheezing non-productive coughing tachycardia tachypnea later cough becomes productive with nasal flaring and cyanosis of lips |
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Term
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Definition
PFT ABGs- arterial blood gas
Note: Asthma occurs in families |
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Term
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Definition
bronchodilators steroids leukotriene inhibitors |
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Term
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Definition
Exercise Induced (bronchodilators 20-30 min. prior to ex)
Intrinsic - nonallergic; adult onset; secondary to chronic infection
Extrinsic- Allergic Asthma |
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Term
Bronchiectasis (bron-kee-ek-ta-sis)
Definition |
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Definition
A progressive form of obstructive lung disease characterized by irreversible destruction and dilation of A/Ws associated with chronic bacterial infections |
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Term
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Definition
Coughing up blood or bloody sputum |
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Term
Bronchiectasis
Disease process |
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Definition
Chronic dilation of bronchi and bronchioles with wet secretions that plug airways and cause more purulent mucous causing bronchospasm.
Destruction of bronchial walls occur with fibrosis that further obstructs lumen |
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Term
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Definition
persistent coughing increased amounts of sputum (gray and smelly) anemia fever may have hemoptysis weight loss weakness |
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Term
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Definition
chest PT
Bronchodilators
Antibiotics
Poor prognosis. Rare condition. |
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Term
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Definition
Severe inflammation of the lower airways caused by viral infection. |
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Term
Bronchiolitis Disease process |
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Definition
bronchiolar mucosa swells and fills with mucus.
Hyperinflation and obstruction occur Most Common in Children<2 yrs (preemies)
Associated with RSV*
*(Respiratory syncytial virus) |
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Term
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Definition
Cough
Respiratory Distress
Cyanosis |
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Term
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Definition
Episodes of cessation of breathing occurring at transition from NREM to REM with repeated awakenings
Defined as more than five cessations for at least 10 sec each per hour |
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Term
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Definition
Central Apnea-related to CNS
Obstructive Apnea-related to obesity etc. |
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Term
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Definition
narrowed upper A/Ws obesity adenoid uvula and tonsil hypertrophy smoking |
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Term
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Definition
snoring breath cessation thrashing mov’t of extremities daytime sleepiness headaches personality changes |
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Term
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Definition
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Term
Restrictive Lung Diseases |
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Definition
(Some type of restriction) limits lung expansion – can not get air into the lungs |
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Term
Restrictive Lung Diseases
Signs and Symptoms |
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Definition
Chronic hyperventilation Initially DOE Later, dyspnea @ rest Respiratory muscle fatigue leading to decreased alveolar ventilation and increased CO2 retention hypoxemia |
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Term
Restrictive Lung Diseases
Causes |
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Definition
Weakness from Neuromuscular Disease
Interstitial Lung Diseases |
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Term
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Definition
Excessive fibrous tissue in lung that replaces normal tissue due to chronic inflammation Also known as interstitial lung disease (See causes of Restrictive Lung Diseases) |
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Term
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Definition
healing scar tissue after TB systemic sclerosis ARDS = Adult respiratory distress syndrome Inhalation of toxic substances ~2/3 of cases are idiopathic |
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Term
Pulmonary Fibrosis
Dx and Prognosis |
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Definition
RX - corticosteriods Poor prognosis |
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Term
Systemic Sclerosis and Lung Disease
Def |
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Definition
Scleroderma-autoimmune disease of connective tissue with excessive collagen deposition in skin and internal organs (Skin and organs slowly become thicker and less flexible) |
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Term
Systemic Sclerosis and Lung Disease
Disease progression |
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Definition
skin changes generally precede visceral alterations unpredictable course – ½ develop interstitial lung disease (AKA Pulmonary Fibrosis) |
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Term
Systemic Sclerosis and Lung Disease
Rx |
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Definition
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Term
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Definition
A variety of conditions including: *Superficial wounds of the chest wall *Tension Pneumothorax *Flail Chest |
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Term
Chest Wall Disease
Pneumothorax |
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Definition
Occurs when air leaks into the space between your lungs and chest wall, creating pressure against the lung.
The lung can partially or completely collapse. |
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Term
Chest Wall Disease
Flail Chest |
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Definition
2 or more fxs of adjacent ribs on the same side or of the sterum, may cause paradoxical mov’t of chest |
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Term
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Definition
pain meds mechanical ventilation may be needed |
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Term
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Definition
Group of disorders caused by lung damage resulting from inhalation of industrial substances (iron,coal dust, asbestos, silica, talc, beryllium). Exposure over 10 yrs |
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Term
Pneumonconiosis
Disease Process |
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Definition
Smaller dust particles are more dangerous-reach smaller airways. Particles are indestructible and produce an inflammatory process that results in excess fibrosis |
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Term
Pneumonconiosis
Signs and symptoms |
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Definition
Progressive dyspnea-1st DOE then DO rest chest pain chronic cough expectoration of mucus |
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Term
Hypersensitivity Pneumonitits
Def |
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Definition
Extrinsic allergic alveolitis resulting from – environmental exposure – mold, sugar cane, fungal spores etc. |
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Term
Hypersensitivity Pneumonitits
Disease Process |
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Definition
immune complex-mediated and Tcell-mediated hypersensitivity. Symptoms begin abruptly with exposure -Occur again with repeat exposure |
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Term
Hypersensitivity Pneumonitits
Signs and Symptoms |
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Definition
dyspnea fever chills nonproductive cough
Mild fibrous can occur |
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Term
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Definition
mucosal injury via hot gases (Burns)
asphyxia as 02 is consumed by fire
Burns in upper airway produces edema and obstruction
-possibility of cascade -poor prognosis |
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Term
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Definition
Inherited disease of exocrine glands. Affects hepatic,digestive, male reproductive system and respiratory system |
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Term
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Definition
Altered chloride and sodium channels Dehydration with increased viscosity of secretions from mucous glands -lungs -pancreas -intestines -sweat glands -pancreatic enzyme insufficiency -high salt content in sweat |
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Term
CF
Disease Process 2-Pulmonary Aspect |
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Definition
Progresses from mucus plugging of small airways to bronchitis, then bronchiectasis, pneumonia and fibrosis; later involves all bronchi |
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Term
CF
Disease Process 3-Pancreatic aspect |
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Definition
Thick secretion block ducts preventing enzymes from reaching the -duodenumresults in fatty stools |
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Term
CF
Signs and Symptoms #1 -Pancreatic/digestive aspect |
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Definition
meconium ileus at birth prolapse of the rectum risk of impaction |
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Term
CF
Signs and Symptoms #2 -Pulmonary Aspect |
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Definition
chronic cough and sputum production increased risk of infection reduced oxygen CO2 exchange acidosis |
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Term
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Definition
sweat test (salt content) stool fat measurements pancreatic elastase-1 |
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Term
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Definition
antibiotics drugs to thin secretions adequate hydration nutritional support pancreatic enzymes mucolytics CPT exercise |
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Term
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Definition
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Term
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Definition
Obstructive-absorptive Type Compressive Type |
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Term
Atelectasis
Obstructive-absorptive type |
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Definition
collapse resulting from removal of air from obstructed or hypoventilated alveoli |
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Term
Atelectasis
Compressive Type |
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Definition
collapse due to air, blood or fluid filling the pleural space |
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Term
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Definition
dyspnea tachypnea cyanosis fever decreased BP shock |
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Term
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Definition
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Term
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Definition
remove cause suctioning or bronchoscopy prevention (especially in postsurgical patients) breathing exercises percussion/vibration |
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Term
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Definition
Fluid in the lungs which leak into interstitial tissue and in alveoli |
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Term
Pulmonary Edema
Causative Factors |
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Definition
Results from left ventricular failure Acute HBP mitral valve disease Noncardiac causes-liver disorders and kidney disorders in which there is sodium and water retention Specifically from fluid overload, increased capillary permeability, decreased albumin, and increased lymphatic obstruction |
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Term
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Definition
peristant cough dyspnea diaphoresis (sweating) intolerance to ex. As fluid increases, these signs become more pronounced.
cough may produce a pink frothy sputum, wheezing occurs and resp rate increases |
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Term
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Definition
clinical presentation and c-xray |
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Term
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Definition
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Term
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Definition
Adult Respiratory Distress Syndrome
Result of injury to the lung by a variety of disorders – a collection of symptoms |
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Term
ARDS
Disease Process Part 1 |
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Definition
Damage to capillary endothelial cells and alveolar epithelial cells which inactivates surfactant and allows fluids, proteins, and cells to leak from capillary |
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Term
ARDS
Disease Process Part 2 |
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Definition
Leads to pulmonary edema and alveolar collapse, impairment of lung compliance |
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Term
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Definition
initially increased resp rate then dyspnea, hyperventilation, cyanosis |
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Term
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Definition
exam of ABGs (arterial blood gasses) and microbiologic cultures xrays |
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Term
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Definition
treat underlying condition, ventilation |
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Term
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Definition
unpredictable pulmonary fibrosis may result mortality rate is 50-70% if accompanied with sepsis-90%
-may seem fine in 1st 24hrs then crash |
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Term
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Definition
Systemic disease of unknown cause Granulomas throughout body Lungs and lymph nodes commonly affected |
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Term
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Definition
dyspnea, dry cough, fever, skin lesions |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Most frequent cause of CA death in the US Classified as small cell lung CA (SCLC) or NSCLC |
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Term
Lung Cancer
Four Major Types |
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Definition
SCLS: 1) Oat Cell NSCLC: 2) Squamous Cell Carcinoma 3) Adenocarcinoma 4) Large Cell Carcinoma |
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Term
Lung Cancer
Frequency of each type |
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Definition
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Term
Lung CA
Small Cell (Oat Cell) |
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Definition
cells become so dense that there is almost no cytoplasm -compressed into an ovoid mass. Located centrally near hilum. Rapid growth rate with early mets. Secretes ACTH. |
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Term
Lung CA
Small Cell (Oat Cell) Symptoms |
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Definition
Early stage symptoms do not differ from pulmonary sx associated with smoking |
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Term
Lung CA
Small Cell (Oat Cell) Rx |
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Definition
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Term
Lung CA
NSCLC - Squamous Cell |
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Definition
Growths arise in central potion of lung near hilum, projecting into bronchi, have a central cavity, stays local longer (slower mets) |
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Term
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Definition
mod growth rate growths arise in periphery of lung early mets |
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Term
Lung CA
Large Cell Carcinoma |
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Definition
peripheral pulmonary tumors that cause sharp and significant pleural pain early mets poorest prognosis |
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Term
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Definition
Sx also depend on location: central tumors obstruct airflow peripheral tumors only produce pain when pleura is affected, may limit lung expansion |
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Term
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Definition
Tumors of apex of lung invade brachial plexus (shoulder pain) |
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Term
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Definition
via xray CT lung imaging fluorescence endoscope bronchoscopy |
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Term
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Definition
surgery with lymph node resection radiation, and chemo.
Surgery choice in NSCLC and chemo. Radiation in SCLC with chemo |
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Term
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Definition
spread by extension, lymphatics and through vascular system; often to brain, liver, and bone (long bones and spine esp T-spine producing chest shoulder, arm or back pain) |
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Term
Lung CA
Paraneoplastic Syndromes |
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Definition
effects of malignancy felt remotely-hypercalcemia osteoarthropathies DVT |
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Term
Pulmonary Embolism (PE)
Def |
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Definition
Lodging of blood clot in a pulmonary Artery with subsequent obstruction of blood supply to lung parenchyma |
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Term
Pulmonary Embolism (PE)
Risk Factors |
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Definition
blood stasis 2nd to immobilization endothelial injury 2nd to surgery trauma hypercoagulable states (BCP) DVT (VTE) obesity smoking HTN malignancy fxs of hip or femur |
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Term
Pulmonary Embolism (PE)
Signs |
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Definition
Signs depend on the size of the PE- homans sign pleuritic chest pain persistent cough hemoptysis diaphoresis fever tachypnea sudden death |
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Term
Pulmonary Embolism (PE)
Prevention |
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Definition
Prevention is key given high mortality
– LMW Heparin-prevent clot extension thrombolytic therapy to lyse emboli, greenfield filter in vena cava |
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Term
Pulmonary Embolism (PE)
Implications for PT |
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Definition
consider the possibility of PE following hip and knee surgery
avoid the following: restrictive clothing crossing legs prolonged sitting pillow under knees in supine extreme flexion at hips |
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Term
Pulmonary Embolism (PE)
If DVT or PE has been Dx'd |
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Definition
no massage to legs watch for any evidence of bleeding |
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Term
Pulmonary Embolism (PE)
Prevention |
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Definition
bed exercises for the LEs, compression stockings, early ambulation, hydration |
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Term
Pulmonary Hypertension
Def |
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Definition
HBP in pulmonary arteries. 5-10 mm Hg above normal (15-18 mm Hg) |
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Term
Pulmonary Hypertension
Types |
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Definition
Primary Pulmonary Hypertension
Secondary Pulmonary Hypertension |
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Term
Pulmonary Hypertension
Primary-Cause |
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Definition
narrowing of pulmonary arterioles by hypertrophy of smooth muscles |
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Term
Pulmonary Hypertension
Secondary-Cause |
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Definition
increases in volume or pressure of blood entering the pulmonary arteries |
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Term
Pulmonary Hypertension
Sx (both) |
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Definition
fatigue tachypnea cyanosis dyspnea |
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Term
Pulmonary Hypertension
Rx (both) |
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Definition
oxygen for hypoxemia digitalis diuretics |
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Term
Pulmonary Hypertension
Prognosis (both) |
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Definition
Poor w/o heart-lung transplant |
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Term
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Definition
Also called pulmonary heart disease Enlargement of right ventricle secondary to pulmonary hypertension |
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Term
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Definition
Related to pulmonary disorder (cough,exertional dyspnea, wheezing). Exercise induced peripheral cyanosis distended neck veins peripheral edema Low cardiac output causes pallor sweating hypotension impaired consciousness |
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Term
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Definition
reduce workload of right ventricle |
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Term
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Definition
Inflammation of the pleura caused by infection, injury or tumor |
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Term
Pleurisy
Signs and Symptoms |
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Definition
Sharp sticking chest pain worse on inspiration, coughing or with movement, also cough, fever, and rapid shallow breathing may be present. Pleural rub |
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Term
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Definition
Diaphragmatic Wet pleurisy Dry Pleurisy |
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Term
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Definition
refers pain to neck, supraclavicular fossa, and upper trap |
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Term
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Definition
less likely to cause pain because the fluid content increases |
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Term
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Definition
causes pain due to the the layers rubbing against each other |
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Term
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Definition
Collection of fluid in the pleural space (space btw. 2 pleural layers)
Any condition that interferes with the drainage or secretion of this fluid will lead to pleural effusion |
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Term
Pleural Effusions
Etiology |
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Definition
– Transudates Abnormalities of the hydrostatic or osmotic pressure CHF, Cirrhosis with ascities – Exudates Increased permeability or trauma Infection, PE, surgical trauma |
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Term
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Definition
Accumulation of air or gas in pleural cavity caused by defect in visceral pleura, results in collapsed lung |
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Term
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Definition
SOB, hypoxia, mediastinal shift toward the unaffected side compressing the opposite lung |
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Term
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Definition
"bleb" collection of air within layers of viscera pleura "bulla" air-filled, thin-walled space within lung (destruction of alveoli) |
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Term
Pulmonary Pain Patterns
Tracheobronchial pain |
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Definition
referred to sites in the neck and ant chest at the same levels as the points of irritation in the air passages |
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Term
Pulmonary Pain Patterns
Bronchi |
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Definition
innervated by vagus but finer bronchi and lung parenchyma are free of pain innervation |
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Term
Pulmonary Pain Patterns
Diaphragmatic Pleura |
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Definition
receives dual pain inervation through phrenic and intercostal nerves-sharp pain to upper traps and shoulder |
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Term
Pulmonary Pain Patterns
Pleuropulmonary disorders |
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Definition
substernal or chest over involved lung fields, may radiate to neck, upper traps, shoulder, or upper abdomen. Thoracic back pain occurs with irritation of the posterior parietal pleura. May be sharp or stabbing |
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Term
Pulmonary Pain Patterns
Lung CA |
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Definition
Ant chest with referral to scapula, upper back, shoulder, may radiate along the medial aspect of arm. Sharp pleuritic pain |
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