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Details

Pulm-Pharm
General Anesthetics
14
Pharmacology
Graduate
10/08/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Progressive Depth of Anesthesia
Definition

I. Analgesia

II. Excitement: Disinhibit, Unresponsive Thrash

III. Surgical Anesthesia

IV. Medullary Depression: CV and Pulm Collapse

Term
Goals of Anesthesia
Definition

Homeostasis: O2 and CO maintainence

Protect Patient

Optimal for Surgeon

Post-Operative Care

Term
Minimum Alveolar Concentration
Definition
Concentration of anesthesic that 50% of patients don't move
Term
Factors affecting the onset of Anesthesia
Definition

Solubility

Concentration Dose

Venous Concentration

Ventilation

Cardiac Output

 

 

Term
Physiological effects of inhaled anesthetics
Definition

Sympathetics:Veno/Vasodialation, Bradycardia

CV: Lower Intropy, SA Node firing

Respiratory: Increase Rate, Decrease TV, Decrease minute ventilation, Increase CO2 threshold

Brain: Increase Cerebral blood flow

Term
Inhaled Anesthetics that have toxicity
Definition

Sevoflurane: Renal, Respiratory

Enflurane: Renal

Halothane: Hepatic

All can show Malignant Hyperthermia

 

Term
What drug is used to counter Malignant Hyperthermia
Definition
Dantrolene
Term
How are the effects of IV anesthesics different than Inhaled
Definition
IV do not increase brain blood flow
Term
Mechanism of Benzodiazepines
Definition
Sedative with Amnesia, but not analgesia
Term
What is used to help reverse benzodiazepines respiratory depression?
Definition
Flumazenil(Partial Agonist)
Term
Mechanism of narcotics used in Anesthesia
Definition
Analgesia, not Amnesia
Term
Effects of ketamine as an anesthestic
Definition
Dissociative Anesthesia, Airway Reflexes, Increase ICP
Term
Which Local Anesthetics show more allergies
Definition
Esters
Term
Why can't Nitrous be used alone in inducing anesthesia
Definition
The MAC is to high, so at that partial pressure there would not be enough O2 for the patient
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