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Public Health - Epidemology Glossary
Description of common CDC terms
16
Health Care
Undergraduate 3
01/25/2010

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Term
Agent
Definition
A biological, physical, or chemical entity capable of causing disease.
Term
Anamnestic Response
Definition
The accelerated rise in antibody titer in a person who had previously developed a primary immune response to the particular antigen.
Term
Antibiogram
Definition
A list of those antibiotics to which a particular organism is sensitive or resistant.
Term
Antibiotic Sensitivity Testing
Definition
The identification of the concentration of various antibiotics to which a particular microorganism is sensitive.
Term
Antibody
Definition
A globulin, found in tissue fluids and blood serum, produced in response to the stimulus of a specific antigen, and capable of combining with that antigen to neutralize or destroy it.  Globulins are often referred to as "immune substances".
Term
Antigen
Definition
That portion or product of a biologic agent capable of stimulating the formation of specific antibodies.
Term
Antigenic Character
Definition
The chemical arrangement of the Antigenic components of an agent, which arrangement and components are unique to each species or strain of agents, and which are responsible for the specificity of immunity resulting from infection with that agent.
Term
Antigenicity
Definition
Ability of an agent or its products to stimulate the formation of antibodies.
Term
Antisepsis
Definition
The prevention of sepsis by inhibition or destruction of the causative organism.
Term
Antitoxin
Definition
Antibody to the toxin of a microorganism, usually a bacteria exotoxin. Antitoxin combines with specific toxin, in vivo and in vitro, with the consequent neutralization of toxicity.
Term
Asepsis
Definition
The absense of infectious microorganisms.
Term
Aseptic Technique
Definition
Procedures designed to exclude infectious agents.
Term
Carrier
Definition
A person or animal that harbors a specific infectious agent (but manifests no discernible clinical disease) and is a potential source of infection for man or animals.

The carrier state can occur in an indiviudal with an infection innaparent throughout its course or, if the infection leads to disease, the carrier state may only occur during the incubation, convalescent, and post-convalescent periods.

While in these states, a person or animal is commonly referred to as incubatroy carrier or convalescent carrier.

The carrier state can be of short or long duration (temporary carrier or chronic carrier).
Term
Case
Definition

An infected or diseased person or animal having specific clinical, laboratory and epidemiologic characteristics.

 

Confimed Case: A person from whom a disease-producing agent has been isolated and identified or from whom has been obtained other laboratory evidence of the presence of an etiologic agent, i.e., a four-fold or greater rise in antibody titers between acute and convalescent serum specimens, whether or not that person has a clinical syndrome indicative of the disease caused by the agent.

 

Presumptive Case:  A person with a clinical syndrome compatible with a disease but without laboratory confirmation of the etiologic agent.

Term
Cohort
Definition
Any defined group of persons selected for a specific purpose or study.
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