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Psychopharmacology
Physio Psych Ch 4 Lect 3
18
Psychology
Graduate
04/28/2009

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Term
Intraperitonal
Definition
Around stomach, intestines, liver, and other abdominal organs.
Term
antagonist, agonist
Definition
(re: drugs) An _________ opposes or inhibits effects of a NT on the postsynaptic cell; an _____ facilitates.
Term
Direct agonist
Definition
Drug that binds with and activates a receptor.
Term
Receptor blocker AKA direct antagonist
Definition
A drug that binds with a receptor but does not activate it, prevents natural ligand from binding with receptor.
Term
Noncompetitive binding
Definition
Binding of a drug to a cite on a receptor, doesn't interfere with bindign site for principal ligand.
Term
Indirect antagonist; indirect agonist
Definition
A drug that attaches to a binding site on a receptor and interferes with teh action receptor is an ______, one that facilitates is _________. Neither interferes with teh binding site for the primary ligand.
Term
Acetyl CoA
Definition
Cofactor that supplies acetate for the synthesis of acetylcholine.
Term
Acetylcholine
Definition
The primary NT secreted by EFFerent axons of teh CNS. Accomplishes all muscle movement.
Term
Monoamines
Definition
A class of amines including indolamiones and catecholamines, modulate function of widespread regions of the brain by increasing or decreasing activities of brian functions.
Term
Dopamine, norepinephrine, epinephrine, seratonin
Definition
Name four Monoamines (the first three are catecholamines).
Term
Nigrostriatal System, Mesolimbic system, mesocortical system
Definition
Three main dopaminergic pathways
Term
Glutamate, GABA, Glycine
Definition
Name 3 important amino acids.
Term
Peptides
Definition
Two or more amino acids linked by peptide bonds.
Term
Nucleosides; adenosine
Definition
This is a compound that consists of a sugar molecule bound with a purine or pyrimidine base; __________ is a compound that serves as a neuromodulator in the brain.
Term
Therapeutic index
Definition
Ratio of dose producing 50% desired effect, 50% lethal dose.
Term
Gluatamate, GABA
Definition
All neurons in CNS respond to these two neurotransmitters:
Term
Learning; vigilance, decreased impulsivity
Definition
What circuits do these neurotransmitters turn on? ACh; NE (norepinephrine); 5-HT (seratonin)
Term
Botulinum, Black widow spider venom
Definition
______ blocks release of ACh, _______ stimulates release of ACh.
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