Term
Definition of schizophrenia |
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Definition
severe, chronic psychotic illness which results in decline in long term psychosocial and occupational functioning |
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Term
Characteristics symptoms of schizo |
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Definition
hallucinations- perception w/o ext. stimuli delusions- firmly held erroneous beliefs incongruent with culture disorganization grossly disorganized behavior/catatonic behavior "negative symptoms"
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Term
Examples of negative symptoms |
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Definition
affective flattening diminish emotional expressiveness apathy anergia asociality attentional impairment avolition- inability to initiate and persist in goal directed activities alogia- poverty of speech and its content
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Term
Define milder symptoms of schizo |
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Definition
similar to active symptoms, but less intense |
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Term
What would exclude somebody from being schizo? |
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Definition
prominent affective states contributory substance, medication, or medical condition autism/PDD (developmental disorder)
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Term
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Definition
prodromal (subtle changes) active (psychotic symptoms develop) interepisode (new baseline of functioning) residual (attenuated positive symptoms, impact of negative symptoms, re-emergence of active phase symptoms)
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Term
epidemiology of schizophrenia |
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Definition
usually mean age of 21 for me and 27 for women seen in winter births, first degree relatives of schizophrenics gestational/delivery complications afflicts slightly more men than women
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Term
neuropathology of schizophrenia |
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Definition
increase ventricular size decrease brain volume abnormal migration of neurons loss of normal cortical asymmetry (you should have larger left side, but schizo has more symmetrical brain) increase glutamate (ex: PCP bind NMDA R)
OVERACTIVITY OF DOPAMINE (drugs that antagonize dopamine) |
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Term
Treatment of schizophrenia |
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Definition
evaluate for patient safety antipsychotic medication no specific treatment for negative symptoms adjunctive medications (ex: for agitation, moods, impulsivity) NMDA receptor modulators in near future
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Term
psychosocial interventions in schizophrenia |
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Definition
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Term
Different types of "schizos" |
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Definition
acute psychotic (symptoms less than month) schizophreniform (symptoms (1-6 mnths) schizophrenia (symptoms more than 6 mnths)
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Term
Symptoms of schizoid personality disorder |
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Definition
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Term
Symptoms of schizotypal personality |
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Definition
odd, eccentric mannerisms, appearance odd beliefs or magical thinking
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