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Psychiatry
Pathology
155
Pathology
Graduate
01/17/2014

Additional Pathology Flashcards

 


 

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Term
evidence of:
- physical abuse
- sexual abuse
Definition
- healed fractures on XR, cigarett burns, subdural hematomas, multiple bruises, retinal hemorrhage or detachment
- genital/anal trauma, STDs, UTI
Term
abuser in:
- physical abuse
- sexual abuse
Definition
- usually female and the 1' caregiver
- known to victim, usually male
Term
epidemiology
- physical abuse
- sexual abuse
Definition
- ~300 deaths/year in US
- peak incidence 9-12 y/o
Term
child neglect
Definition
failure to provide child with adequate food, shelter, supervision, education and/or affection; most common child maltreatment; poor hygiene, malnutrition, withdrawal, impaired social/emotional development, failure to thrive
Term
long term infant deprivation effects
Definition
dec mm tone, poor language skills, poor socialization skills, lack of basic trust, anaclitic depression, weight loss, physical illness
Term
ADHD symptoms
Definition
hyperacitivy, motor impairmment and emotional lability; limited attention span and poor impulse conrol; normal intelligence
Term
ADHD
- brain area
- treatment
Definition
- dec frontl lobe volumes
- mathylphenidate, amphetamines, atomoxetine
Term
conduct disorder
Definition
repetitive and pervasive behaior violating social norms (physical aggression, destruction of property, theft, cruelty to animal)
Term
oppositional defiant disorder
Definition
enduring pattern of hostile, defiant behavior toward authority figures in absence of serious violations of social norms
Term
tourette's symptoms
Definition
sudden, rapid, recurrent, nonrhthmic, stereotyped motor movements of vocalizations that persists for >1 year
Term
coprolalia
Definition
obscene speech found in only 20% of tourettes
Term
tourette tx
Definition
antipsychotics (haloperidol)
Term
separation anxiety disorder
Definition
overwhelming fear of separation from home or loss of attachment figure; factitious physical complaints to avoid going to school
Term
autistic disorder symptoms
Definition
language impairment and poor social interactions; greater focus on objects that on people; repetitive behavior and usually below normal intelligence
Term
autistic disorder tx
Definition
behavioral and supportive therapy to improve communication and social skills
Term
asperger's disorder
Definition
milder form of autism; all-absorbing interests, repetitive behavior and problems with social relationships; normal intelligence and lack verbal or cognitive deficits
Term
Rett's disorder
Definition
X-linked disorder almost exclusively in girls; regression characterized by loss of development, loss of verbal abilities, MR, ataxia and stereotyped hand wringing
Term
child disintegrative disorder
Definition
marked regression in multiple areas of functioning after at least 2 years of pparently normal development; loss of expressive or receptive languat skills, social skills or adaptive behavior; boys
Term
NT changes in: anxiety
Definition
inc NE
dec GABA, 5HT
Term
NT changes in: depression
Definition
dec NE, 5HT, DA
Term
NT changes in: alzeimer's
Definition
dec Ach
Term
NT changes in: Huntington's
Definition
dec GABA, Ach
inc DA
Term
NT changes in: schizophrenia
Definition
inc DA
Term
NT changes in: parkinson's
Definition
dec DA, 5HT
inc Ach
Term
orientation
Definition
time place and person
Term
common causes of loss of orientation
Definition
alcohol, drugs, fluid/electrolyte imbalance, head trauma, hypoglycemia, nutritional deficiencies
Term
"waxing and waning" level of consciousness with acute onset
Definition
delerium
Term
delerium characteristics
Definition
acute changes in mental status, disorganized thinking, hallucinations, illusions, misperceptions, disturbance in sleep-wake cycle, cognitive dysfunction
Term
abnormal EEG
Definition
delerium
Term
gradual dec in intellectual ability or "cognition" without affecting level of consciousness
Definition
dementia
Term
dementia characteristics
Definition
memory deficits, aphasia, apraxia, agnosia, loss of abstract though, behavioral/personality changes, impaired judgment
Term
causes of dementia
Definition
Alzheimer's, cerebral vascular infarcts, HIV, Pick's disease, chronic substance abuse, CJD
Term
excesive dieting +/- purging
Definition
anorexia nervosa
Term
intense fear of gaining weight, body image distortion, and inc exercise
Definition
anorexia
Term
eating disorder that coexists with depression
Definition
anorexia
Term
eating disorder with dec bone density
Definition
anorexia
Term
binge eating +/- purging
Definition
bulimia
Term
body weight often maintained with this eating disorder
Definition
bulimia
Term
eating disorder with parotitis
Definition
bulimia
Term
Russell's sign
Definition
dorsal hand calluses from induce vomiting
Term
transexualism
Definition
desire to live as the opposite sea; often through surgery or hormone tx
Term
transvestism
Definition
paraphilia; wearing clothes of the opposite sex
Term
signs of substance dependence
Definition
tolerance; withdrawal; substance taken in larger amounts or over longer time than desired; persistent desire or unsuccessful tempt so cut down; significant energy spent on obtaining, using or recovering from substance; social, occupational or recreational activities reduced because of substance use; continue use in spite of knowledge the problem that it causes
Term
features of substance abuse
Definition
recurrent use resulting in failure to fulfill major obligations; recurrent use in physically hazardous situations; recurrent substance-related legal problems; continued use in spite of persistent problems caused by use
Term
stages of overcoming substance addiction
Definition
precontemplation, contemplation, preparation/determination, action/willpower, maintenance, relapse
Term
depressants: intoxication vs withdrawal
Definition
intox = mood elevation, dec anxiety, sedation, behavioral disinhibition, respiratory depression
withdrawal= anxiety, tremor, seizures, insomnia
Term
amotional lability, slurred speech, ataxia, coma, blackouts
Definition
alcohol intoxication
Term
if sever can go to delirium tremens
Definition
alcohol withdrawal
Term
CNS depression, N/V, pinpoint pupils, constipation, seizures
Definition
opioids
Term
opioid OD treatment
Definition
naloxone, naltrexone
Term
sweating, dilated pupils, piloerection, fever, rhinorrhea, diarrhea
Definition
opioid withdrawal
Term
low safety margin, marked respiratory depression
Definition
barbiturates
Term
barb intoxication tx
Definition
symptoms management
Term
delerium, life-threatiening cardiovascular collapse
Definition
barb withdrawal
Term
ataxia, minor respirtatory depression; greater safety margin
Definition
benzodiazepines
Term
benzo OD tx
Definition
flumazenil
Term
stimulants intoxication vs withdrawal
Definition
intox = mood elevation, psychomotor agitation, insomnia, carida arrhythmias, tachycardia, anxiety
withdrawal= pose-use "crash", depression, lethargy, weight gain, HA
Term
impaired judgment, pupillary dilation, wakefulness and attention, delusions, hallucinations
Definition
amphetamines
Term
stomach cramps, hunger, hypersomnolence
Definition
amphetamine withdrawal
Term
impaired judgement, pupillary dilation, hallucinations, paranoid ideations, angina, sudden cardiac death
Definition
cocain
Term
cocain intoxication tx
Definition
benzodiazepines
Term
suicidality, hypersomnolence, malaise, sever psychological caving
Definition
cocaine withdrawal
Term
restlessness, inc diursis, mm twitching
Definition
caffeine
Term
irriability, anxiety, craving
Definition
nicotine withdrawal
Term
nicotine wihdrawal tx
Definition
nicotine gum, patch, or loanges; bupropion/varenicline
Term
belligerence, impulsivement, fever, agitation, vertical and horizontal nystagmus, delirium
Definition
PCP
Term
depresison, anxiety, irritability, restlessness, anergia, disturbances of though and sleep
Definition
PCP
Term
PCP intoxication tx
Definition
benzo, haloperidol
Term
marked anxiety/depression, delusions, visual hallucinations, flashbacks, pupillary dilation
Definition
LSD
Term
euphoria, anxiety, paranoid delusions, slowed time, impaired judgment, social withdrawal
Definition
marijuana
Term
irritability, depression, insomnia, nausea, anorexia
Definition
maruijuana withdrawal
Term
what are heroic addicts at risk for?
Definition
hepatitis, abscesses, overdose, hemorrhoids, AIDS and R-sided endocarditis
Term
methadone
Definition
long acting oral opiate; for heroin detox or long-term maintenance
Term
suboxone
Definition
naloxone + buprenorphine; long acting with fewer withdrawal symptoms than methadone
Term
complications of alcoholism
Definition
alcoholic cirrhosis, hepatitis, pancreatitis, peripheral neuropathy, testicular atrophy
Term
wernicke's encephalopathy
Definition
confusion, opthalmoplegia, and ataxia
Term
korsakoff's psychosis
Definition
irreversible memory loss, confabulation, personality change; anterograde memory loss and some retrograde; maxillary body destruction
Term
brain lesion in wernicke-korsakoff
Definition
hemorrhage/necrosis of mamilary bodies
Term
mallory-weiss syndrome
Definition
longitudinal lacerations at GE junction caused by excessive vomiting
Term
tx of alcoholism
Definition
alcoholic anonyous, supportive care, disulfuram
Term
delerium tremens symptoms
Definition
automonic system hyperactivity (tachycardia, tremors, anxiety, seizures, psychotic symptoms (hallucinations, delusion), confusion
Term
tx of DT
Definition
benzodiazepines
Term
infant deprevation effects
Definition
dec mm tone, poor language, poor socialization, lcm of basic trust, anaclitic depression, weight loss, physical illness
Term
retrograde amnesia
Definition
inability to remember things tha occurred before a CNS insult
Term
anterograde amnesia
Definition
inability to remember things that occurred after a CNS insult
Term
dissociative amnesia
Definition
inability to recall important personal information, usually subsequent to severe trauma or stress
Term
cognitive disorder
Definition
significant change in cognition (memory, attention, language, judgment) from previous level of functioning. associated with abnormalities in CNS, a general medical condition, medications or substance use.
Term
psychotic disorder
Definition
a distorted perception of reality characterized by delusions, hallucinations and/or disorganized thinking. with medical illness, psychiatric illness or both
Term
hallucinations
Definition
perceptions in the absence of external stimuli
Term
illusions
Definition
perceiving external stimuli as something they are not
Term
delusions
Definition
false beliefs about oneself or others that persist despite the facts
Term
loose associations
Definition
disorders in the form of thought (the way ideas are tied together)
Term
when see visual hallucinations
Definition
more commonly in medical illness
Term
when see auditory hallucinations
Definition
more commonly with psych illness
Term
when see olfactory hallucinations
Definition
aura or a psychomotor seizure and in brain tumors
Term
when see tactile hallucinations
Definition
common in alcohol withdrawal and cocain abusers
Term
hypnagogic hallucinations
Definition
when going to sleep
Term
hypnopompic hallucinations
Definition
occurs while waking from sleep
Term
5 subtypes of schizophrenia
Definition
paranoid, disorganized, catatonic, undifferentiated, residual
Term
positive symptoms of schizophrenia
Definition
delusions, halluciantions, disorganized speech, disorganized behavior
Term
negative symptoms of schizophrenia
Definition
flatt affect, social withdrawal, lack of motivation, lack of speech or thought
Term
brief psychotic disorder
Definition
<1 month
Term
schizophreniform disorder
Definition
lasts 1-6 months
Term
schizoaffective disorder
Definition
2 weeks of stable mood with psychotic symptoms plus a major depressive, mani or mixed episode
Term
delusional disorder
Definition
fixed, persistent belief system lasting > 1 month; functioning not impaired
Term
folie a deux psychotic disorder
Definition
development of delusion in a person in a close relationship with someone with delusional disorder
Term
dissociative identity disorder
Definition
presence of 2 or more distinct identities or personality states; more common in women
Term
depersonalization disorder
Definition
persistent feelings of detachment or estrangement from one's own body, a social situation or the environment
Term
dissociative fuge
Definition
abrupt change in geographic location with inability to recall past, confusion about personality identity or assumption of a new identity; with traumatic circumstances
Term
features of a manic episode
Definition
distractability, irresponsibility, grandiosity, flight of ideas, inc activity/agitation, dec sleep, talkativeness
Term
hypomanic episode
Definition
mood disturbance is not severe enough to cause marked impairment in social and/or occupational functioning or to necessitate hospitalization
Term
bipolar disorder
Definition
I = at least 1 manic; II = at least one hypomanic; mood and functioning return to normal between episodes
Term
cyclothymic disorder
Definition
dysthymia and hypomania; milder and lsting at least 2 years
Term
features or MDD
Definition
sleep disturbance, loss interest, guilt or feelings of worthlessness, loss of energy, loss of concentration, appetite/weight changes, psychomotor retardation, suicidal ideations
Term
dysthymia
Definition
milder form of depression lasting at least 2 years
Term
seasonal affective disorder
Definition
associated with winter season; improves in response to full-spectrum light exposure
Term
atypical depression characteristics
Definition
hypersomnia, overeating and mood reactivity= ability to experience improved mood in response to positive events vs persistent sadness_ weight gain and sensitivity to rejection
Term
post-partum "blues"
Definition
50-85%; depressed affect, tearfulness and fatigue; improves within 10 days
Term
postpartum depression
Definition
10-15%; depressed affect, anxiety and poor concentration; lasts 2 weeks to 2 months
Term
post partum psychosis
Definition
0.1-0.2%; delusions, confusion, unusual behavior and possible homicidal/suicidal ideations or attempts; 4-6 weeks
Term
ECT
Definition
painless seizure in an anesthetized patient for MDD
Term
risk for suicide completion
Definition
sex, age, depression, previous attempt, ethanol or drug use, loss of rational thinking, sickness, organized plan, no spouse, social support lacking
Term
anxiety disorder
Definition
inappropriate fear/worry and its physical manifestations; symptoms interfere with daily functioning
Term
panic disorder
Definition
10 min with at least 4 of: palpitations, paresthesias, abdominal distress, nausea, intense fear of dying or losing control, intense fear of ding or losing control, light-headedness, chest pain, sweating, shaking, shortness of death
Term
panic disorder tx
Definition
cognitive behavioral therapy, SSRIs, TCAs, benzo
Term
specific phobia
Definition
fear that is excessive or unreasonable and interferes with normal function; cued by presence or anticipation of a specific object or situation; tx with systematic desensitization
Term
social phobia
Definition
exaggerated fear of embarrassment in social situations
Term
OCD
Definition
recurring intrusive thoughts, feelings or sensations that cause severe distress relieved in part by the performance of repetitive actions
Term
ego dystonic
Definition
behavior inconsistent with one's own beliefs and attitudes
Term
PTSD
Definition
nightmares or flashbacks, intense fear, helplessness or horror; avoidance of stimuli associated with the trauma; disturbance lasts > 1 month with onset of symptoms beginning anytime after event
Term
acute stress disorder
Definition
lasts between 2 days and 1 month
Term
GAD
Definition
uncontrollable anxiety for at least 6 months unrelated to a specific person, situation or event; sleep disturbance, fatigue, GI disturbance and difficulty concentrating
Term
adjustment disorder
Definition
emotional symptoms cuasing impairment following an identifiable psychosocial stressor and lasting <6 months
Term
malingering
Definition
consciously fakes or claims to have a disorder to attain a specific 2' gain; poor compliance
Term
munchausen's syndrome
Definition
chronic factitious disorder with predominantly physical signs and symptoms; h/o multiple hospital admission and willingness to receive invasive procedures
Term
munchausen's syndrome by proxy
Definition
when illness in a whole is caused by caregiver; motivation is to assume a sick role by proxy; form of child abuse
Term
somatization disorder
Definition
variety of complaints in multiple organ systems over a period of years
Term
conversion disorder
Definition
sudden loss of sensory or motor function, often following an acute stressor
Term
hypochondriasis
Definition
preoccupation with and fear of having a serious illness despite medical evaluation and reassurance
Term
body dysmorphic disorder
Definition
preoccupation with minor or imagined defect in appearance, leading to significant emotional distress or impaired functioning; patients often repeatedly seek cosmetic surgery
Term
pain disorder
Definition
prolonged pain with no physical findings; predominant focus of clinical presentation and psychological factors play a role in severity, exacerbation or maintenance
Term
personality trait vs disorder
Definition
trait = enduring, repetitive patter of perceiving, relating to and thinking about environment and oneself
disorder= inflexible, maladaptive and rigidly pervasive pattern of behavior causing distress and/or impaired functioning
Term
cluster A personality disorders
Definition
paranoid, schizoid, schizotypal; odd or eccentric, inability to develop relationships, no psychosis
Term
paranoid personality disorder
Definition
pervasive distrust and suspiciousness; projection is major defense mechanism
Term
schizoid personality disorder
Definition
voluntary social withdrawal, limited emotional expression, content with social isolation
Term
schizotypal personality disorder
Definition
eccentric appearance, odd beliefs or magical thinking, interpersonal awkwardness
Term
cluster B personality disorders
Definition
antisocial, borderline, histrionic, narcissistic; dramatic, emotional or erratic; genetic associates with mood disorders and substance abuse;
Term
antisocial personality disorder
Definition
disregard for and violation of rights of others, criminality; malse > females; conduct if <18
Term
borderline personality disorder
Definition
unstable mood and interpersonal relationships, impulsiveness, self-mutilation, boredom, sense of emptiness; females > males; splitting as a defense mechanism
Term
histrionic personality disorder
Definition
excessive emotionality and excitability, attention seeking, sexually provocative, overly concerned with appearance
Term
narcissistic personality disorder
Definition
grandiosity, sense of entitlement; lacks empathy and requires excessive admiration; often demands the best and reacts to criticism with rage
Term
cluster C personality disorders
Definition
avoidant, obsessiv compulsive, dependent; anxious or fearful, genetic association with anxiety disorders
Term
avoidant personality disorder
Definition
hypersensitive to rejection, socialy inhibited, timid, feelings of inadequacy, desires relationships with others
Term
obsessive-compulsive personality disorder
Definition
preoccupation with order, perfectionism and contra; ego syntonic: behavior consistent with one's own beliefs and attitudes
Term
dependent personality disorder
Definition
submissive and clinging, excessive need to be taken, low self-confidence
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