Shared Flashcard Set

Details

Psychiatry
USC PA
74
Medical
Graduate
09/15/2007

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Cards

Term
What antidepressant is a ProDrug?
Definition
Wellbutrin
Term
What neurotransmitters do atypical antipsychotics block that result in therapeutic effects?
Definition
DA, 5HT
Term
What would be a good antidepressant for an elderly person who needs to gain weight?
Definition
Remeron (mirtazepine)
Term
Which antidepressant class can be cardiotoxic?
Definition
TCA

These are antagonists at sodium channels on the heart muscle.
Term
What are some drugs with low therapeutic indexes?
Definition
TCA

Lithium

Barbiturates

Anticonvulsants
Term
Anticholinergic effects?
Definition
Dry mouth

Constipation

Cognitive deficits

Blurred vision
Term
Antihistamine effects?
Definition
Weight gain

Sedation
Term
Antiadrenergic effects?
Definition
Dizziness

Hypotension
Term
Which antidepressants effects are irreversible?
Definition
MAO-I
Term
How does Lithium exert its effects?
Definition
Mostly via 2nd messanger system.

Rapid Na/K exchange slows the speed of repolarization.
Term
What atypical antidepressant is often used to treat insomnia?
Definition
Trazodone
Term
What is the DOC for mania?
Definition
Lithium
Term
List some adverse effects of TCAs?
Definition
1) orthostatic hypotension
2) sedation
3) Anticholingeric
4) CARDIOTOXICITY
5) seizures
6) hyponatremia (decreased Na)
Term
Common adverse effects of Lithium?
Definition
GI dysfunction

Confusion

Thirst

Tremors
Term
How can Lithium toxosis be treated?
Definition
Dialysis
Term
How can Lithium toxosis be treated?
Definition
Dialysis
Term
Which antidepressant has an adverse effect of seizures?
Definition
Wellbutrin
Term
What is apathy?
Definition
absense of emotion; lack of interest or emotional involvement
Term
Which Benzodiazepines should be avoided in the elderly as treatment for insomnia? Why?
Definition
Dalmane, Doral

Long half-life
Term
Which benzodiazepine is often given if there is difficulty falling asleep?
Definition
Halcion
Term
Which benzodiazepine is often given if there is difficulty staying asleep?
Definition
Restoril
Term
Which benzodiazepine is giving for someone who has difficulty falling asleep and staying asleep?
Definition
Dalmane
Term
Adverse effects of benzodiazepines as sleep aids?
Definition
Daytime sedation
Performance impairment
Tolerance
Anterograde amnesia
Daytime anxiety

CNS side effects increase w/age
Term
What 3 drugs fall into the class of non-BZD sedative-hynotics?
Definition
Ambien
Sonata
Lunesta
Term
Which sedative hynotic has a common side effect of bad taste?
Definition
Lunesta
Term
Which sedative-hypnotic drug can be re-dosed during the night?
Definition
Sonata
Term
Which sedative-hypnotic drug is given for people that only have difficulty falling asleep due to its short half-life?
Definition
Ambien
Term
Which sedative-hypnotic drug is used for people that have difficulty falling asleep and staying asleep?
Definition
Lunesta
Term
What drug is used for epilepsy and anesthesia?
Definition
Barbiturates
Term
What drug is used for epilepsy and anesthesia?
Definition
Barbiturates
Term
Which anxiolytic is good for the elderly and addicts?
Definition
Buspar
Term
Which drug for insomnia is the "safest" for use in pregnancy?
Definition
Ambien
Term
What drug is used for treatment of cataplexy and daytime sleepiness associated with narcolepsy?
Definition
Xyrem
Term
What antipsychotic causes QTc prolongation?
Definition
Thioridazine
Term
Which typical antipsychotic is often given IM for rapid tranquilization?
Definition
Haldol
Term
List 4 EPS
Definition
Akathisia (inability to sit still)
Pseudoparkinsonism
Tardive dyskinesia
Acute dystonia
Term
Generic OTC sleep aids?
Definition
diphenhydramine

Doxylamine
Term
Which BZD has the fastest onset?
Definition
Valium (diazepam)
Term
What SSRIs are FDA approved for anxiety?
Definition
Lexapro

Paxil
Term
Which SSRI has the shortest half-life?
Definition
Paxil
Term
Which SSRI has the longest half-life?
Definition
Prozac
Term
Weird cluster for personality disorders?
Definition
Schizoid
Schizotypal
Paranoid
Term
Wild cluster for personality disorders
Definition
Narcissistic
Histrionic
Antisocial
Borderline
Term
Worried cluster for personality disoders
Definition
Obsessive-compulsive
Dependent
Avoidant
Term
DSM-IV axis 1-5
Definition
I: Psychiatric disorder
II. Personality disorder, MR
III. Medical condtions
IV. Psychosocial/environmental
V. GAF
Term
3 P's of insomnia
Definition
Predisposting factors
Precipitating factors
Perpetuating factors
Term
Panic attack heart cluster
Definition
palpitations
chest pain
nausea
Term
Panic attack breathlessness cluster
Definition
SOB
choking sensation
dizziness
chills/hot flashes
paresthias
Term
Panic attack fear cluster
Definition
Fear of dying
fear of going crazy
shaking
sweating
depersonalization
Term
Are benzodiazepines useful in acute stress disorder?
Definition
NO!
Term
Acute stress disorder, time course...
Definition
2 days to 4 weeks
Term
What antihistamine is good for treating anxiety?
Definition
Vistaril
Term
Which antidepressants are used in treating PMDD?
Definition
Sarafem (fluoxetine)
Zoloft
Term
SSRI side effects:
Definition
tremor
agitation
GI dysfxn
sexual dysfxn
Term
4 negative symptoms of schizophrenia
Definition
Avolution
Anhedonia
Affective flattening
Alogia
Term
Prolonged QT syndrome is seen in which antidepressant class?
Definition
TCA's
Term
Which antidepressants tend to be very stimulating?
Definition
SNRI's
Term
Which SSRI's are the most stimulating?
Definition
Prozac

Lexapro
Term
How long before/after MAO-I treatment do you need to wait to start another drug?
Definition
2 weeks
Term
What does MEDIC represent with personality disorders?
Definition
Maladaptive
Enduring
Deviated from cultural norms
Inflexible
Causes impairment in social functioning
Term
How long does brief psychosis last?
Definition
LESS than one week
Term
How long does schizophreniform disorder last?
Definition
>1 month, <6 months

Schizophrenia if the symptoms last longer
Term
What differentiates schizoaffective disorder from schizophrenia?
Definition
Symptoms of mood disorer and psychosis both present but doesn't fall into either category.
Term
What makes delusional disorders different from other psychotic disorders?
Definition
These people are usually high functioning but nonbizarre delusions exist.
Term
Delusion v hallucination
Definition
Delusion is idea/thought

Hallucination is generally more concrete (false sensory perception in absense of "real" external stimuli)
Term
Most important thing to rule out in somatization disorder?
Definition
MDD
Term
Which antipsychotic can cause agranulocytosis?
Definition
Clozapine
Term
Which drug should you use for enuresis?
Definition
impramine
Term
What antidepressant is useful for migranes?
Definition
amitriptyline
Term
Which benzo's have anticonvulsant effects?
Definition
Valium

Ativan
Term
What is the TOC for chronic pain?
Definition
NSAIDS, TCA, SNRI,AED's
Term
TOC for nocturnal myoclonus?
Definition
Klonopin
Term
What is ETC used for?
Definition
PTSD, depression, acute mania
Term
Which TCA is used for pruritis?
Definition
Doxepin
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