Term
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Definition
| maximum therapeutic effect a drug can achieve |
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Term
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Definition
| amount of drug needed to achieve the maximum effect |
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Term
| low vs high potency drugs |
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Definition
| low potency drugs require high doses to achieve therapeutic effects while high potency drugs achieve efficacy at lower doses |
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Term
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Definition
| the time it takes for half of a drug to be removed from the blood stream |
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Term
| time it takes a drug to leave the body after d/c |
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Definition
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Term
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Definition
aka neuroleptics
used to treat the symptoms of psychosis like dellussions hallucinations seen in schizophrenia, schizoaffective disorder and mania of bipolar
off label uses include treatment of anxiety insomnia, agressive behavior ect associated with alzheimers
work by blocking the neurotransmitter dopamine |
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Term
| antipsychotics available by depo injection |
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Definition
prolixin 7-28 days
haldol 4 weeks
risperidone 25mg every 2 weeks
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Term
| elderly patieny concerns with antipsychotics |
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Definition
| increased incidence of death from cardiovascular or infection when using atypical anti psychotics for patiets with dementia related psychosis |
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Term
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Definition
fluhenazine
conventional antipsychotic
phenothiazine |
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Term
|
Definition
Fluxontine Hydrochloride
selective seratonin reuptake inhibitor
antidepressant |
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Term
|
Definition
sertraline
selective seratonin reuptake inhibitor |
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Term
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Definition
Moanamine Oxidase Inhibitor- block
Tyramine Foods interaction (aged cheese, aged meats, beers) cause severe hypertension, hyperpyrexia, tachycardia, diaporesis, tremulousness, cardiac dysrhythmias
SSRI- potential death
common Sfx- sedation , insomnia, weight gain, dry mouth, orthostatic hypotension, sexual dysfunction |
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Term
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Definition
mood stabilizing drug used to treat bipolar dissorder
therapeutic level 1 mEq/L
more than 1.5 is TOXIC |
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Term
|
Definition
typical antipsychotic
butyrophenone class |
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Term
|
Definition
atypical antipsychotic
used to treat bipolar, schizophrenia |
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Term
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Definition
| block dopamine receptors D2, D3, and D4 but also produce many extrapyramidal side Fx |
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Term
|
Definition
block D2 receptors weakly while blocking D3 and D4 which is associated with fewer extrapyramidal side Fx
also inhibit reuptake of seratonin (antidepressant effect) |
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Term
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Definition
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Term
|
Definition
atypical antipsychotic
contraindicated in patients with with a known history of prolonged QT, MI, or uncompensated HF |
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Term
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Definition
new generation atypical antipsychotic
stabilizes dopamine, fewer side effects |
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Term
|
Definition
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Term
|
Definition
antidepressant
4x siezure risk
not for eating dissorders |
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Term
|
Definition
atypical antipsychotic
avoid grapefruit |
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Term
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Definition
| anticonvulsant drug used for mood stabilization |
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Term
|
Definition
conventional antipsychotic
thenothiazine |
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Term
|
Definition
siezures, anxiety, mania
benzodiazapiene
used to manage alcohol withdrawl and anxiety |
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Term
|
Definition
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Term
|
Definition
benzodiazepine
used to manage alcohol withdrawl and anxiety |
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Term
|
Definition
gaba-benzodiazipine agonist
antianxiety agent
depresses CNS through colinergic action on limbic area of brain |
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Term
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Definition
mediates the actions of the amino acid gaba
anxiety, insomnia, ocd, depression, ptsd, alcohol withdrawl
do not d/c abruptly
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Term
|
Definition
Benztropine - is an antiparkinsonian
drug class: antidyskinetics
treatment of Parkinson's Disease
control movement extrapyramidalside effects of antipsychotic drugs prescribed for bipolar disorder.
anticholinergic
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Term
|
Definition
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Term
|
Definition
| IM of Cogentin or Benadryl |
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Term
|
Definition
intense need to move about
treated by change in med
adding beta-blockers, anticholinergic, benzodiazapine |
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Term
|
Definition
may cause agranulocytosis
baseline WBC and q4weeks |
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