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Psych Pharmacology
Lilley Ch 15
31
Nursing
Undergraduate 4
02/19/2011

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Term
Adjunct Therapy
Definition
combination drug therapy used when a patient's condition does not respond adequately to a single drug or when a given combination of medications is known to have therapeutic benefits over a single drug
Term
Affective disorders
Definition
emotional disorders that are characterized by changes in mood
Term
Agoraphobia
Definition
fear of leaving the familiar setting of home
Term
Akathisia
Definition
motor restlessness - a distressing experience of uncontrollable muscular movements that can occur as an adverse effect of many psychotropic medications
Term
Antihistamine
Definition
Any substance capable of reducing the physiologic and pharmacologic effects of histamine, including a wide variety of drugs that block histamine receptors
Term
Antipsychotic
Definition
of or pertaining to a medication that counteracts or diminishes symptoms of psychosis. (older name is neuroleptic)
Term
Anxiety
Definition
the unpleasant state of mind in which real or imagined dangers are anticipated and or exaggerated
Term
Anxiolytic
Definition
Capable of reducing anxiety, usually said of a medication
Term
Benzodiazepine
Definition
the most common group of psychotropic drugs currently prescribed to alleviate anxiety
Term
Biogenic Amine Hypothesis (BAH)
Definition
theory suggesting that depression and mania are due to alterations in neruonal and synaptic amine concentrations, primarily the catecholamines dopamine and norepinephrine, as well as the indolamines serotonin and histamine
Term
Bipolar Disorder (BPD)
Definition
a major psychologic disorder characterized by episodes of mania or hypomania, cycling with depression
Term
Black Box Warning
Definition
a special warning required by the FDA in the commercial drug labeling for drugs that have shown a pattern of major adverse effects
Term
Depression
Definition
an abnormal emotional state characterized by exaggerated feelings of sadness, melancholy, dejection, wortlessness, emptiness, and hoplessness that are inappropriate and out of proportion to reality
Term
Dopamine hypothesis
Definition
views dopamine dysregulation in certain parts of the brain as one of the primary contributing factors to the development of psychotic disorders
Term
Dysregulation hypothesis
Definition
views depression and affective disorders as not simply decreased or increased catecholamine and serotonin activity but as failures of the regulation of these systems
Term
Extrapyrimidal Symptoms
Definition
Refers to symptoms arising adjacent to the pyrimidal portions of the brain. Such symptoms involve various motion disorders similar to Parkinson's disease and are an adverse effect associated with use of various antipsychotic drugs
Term
Gamma-Aminobutyric Acid (GABA)
Definition
an inhibitory amino acid in the brain that functions to inhibit nerve transmission in the CNS
Term
Mania
Definition
A state characterized by an expansive emotional state; extreme excitement; excessive elation; hyperactivity; agitation; over-talkativeness; flight of ideas; increased psychomotor activity; fleeting attention; and sometimes violent, destructive, and self-destructive behavior
Term
Monoamine Oxidase Inhibitor (MAOI)
Definition
any of a heterogeneous group of drugs used primarily in the treatment of depression
Term
Monotherapy
Definition
pharmacologic therapy involving a single medication for a specific condition
Term
Neuroleptic malignant syndrome
Definition
refers to an uncommon but serious adverse effect associated with use of antipsychotic drugs and including such symptoms as fever, cardiovascular instability, and myoglobinemia
Term
Neurotransmitter
Definition
Endogenous chemical in the body that serves to conduct nerve impulses between nerve cells.
Term
Permissive hypothesis
Definition
implicates reduced concentrations of serotonin as the predisposing factor in individuals with affective disorders
Term
Psychosis
Definition
a type of serious mental illness that can take xseveral different forms and is associated with being truly out of touch with reality, that is, unable to distinguish imaginary from real circumstances and events
Term
Psychotherapeutics
Definition
refers to the therapy of emotional and mental disorders. It may involve drug therapy, a variety of counseling techniques, recreational therapy, and, in extreme cases, ECT
Term
Psychotropic
Definition
Capable of affecting mental processes; usually said of a medication
Term
Selective Serotonin Reuptake Inhibitor (SSRI)
Definition
Any of a heterogeneous group of newer medications used to treat depression and certain other mental illnesses. They work by selectively reducing postsynaptic reuptake of the neurotransmitter serotonin in the brain
Term
Serotonin syndrome
Definition
A collection of symptoms resulting from excessive activity of the neurotransmitter serotonin in the brain; may occur with any psychotropic drugs that enhance brain serotonin activity
Term
Stigma
Definition
widespread negative perceptions of and prejudice toward a specific group of people such as those with mental illness
Term
Tardive dyskinesia
Definition
A serious drug adverse effect involving disordered body movements and muscle tension that is associated with antipsychotic medications
Term
Tricyclic
Definition
A chemical class of antidepressant drugs that block reuptake of the amine neurotransmitters serotonin and norepinephrine. They are so named because their chemical structures include a distinctive three-ring segment
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