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The summation of postsynaptic potentials that reach the axon hillock at different times. The closer in time that the potentials occur, the more complete the summation. Compare spatial summation. |
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Also known as chemically gated ion channel. An ion channel that opens or closes in response to the presence of a particular chemical; |
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A receptor protein that does not contain an ion channel but may, when activated, use a G protein system to open a nearby ion channel |
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The form of conduction that is characteristic of myelinated axons, in which the action potential jumps from one node of Ranvier to the next. |
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resting membrane potential |
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A difference in electrical potential across the membrane of a nerve cell during an inactive period |
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An equation predicting the voltage needed to just counterbalance the diffusion force pushing an ion across a semipermeable membrane from the side with a high concentration to the side with a low concentration. |
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An increase in membrane potential (the interior of the neuron becomes even more negative) |
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A variant of the stretch reflex in which stretching of the tendon beneath the knee leads to an upward kick of the leg |
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The fact that the amplitude of the action potential is independent of the magnitude of the stimulus |
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Variation of the concentration of a substance within a region. Molecules and ions tend to move down the concentration gradient from areas of high concentration to areas of low concentration. |
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excitatory postsynaptic potential |
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A depolarizing potential in the postsynaptic neuron that is caused by excitatory connections. EPSPs increase the probability that the postsynaptic neuron will fire an action potential. |
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inhibitory postsynaptic potential |
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A hyperpolarizing potential in the postsynaptic neuron that is caused by inhibitory connections. IPSPs decrease the probability that the postsynaptic neuron will fire an action potential |
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The summation at the axon hillock of postsynaptic potentials from across the cell body. If this summation reaches threshold, an action potential is triggered |
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A receptor protein that includes an ion channel that is opened when the receptor is bound by an agonist. |
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A slow-acting substance in the postsynaptic cell that amplifies the effects of synaptic activity and signals synaptic activity within the postsynaptic cell. |
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A gap between successive segments of the myelin sheath where the axon membrane is exposed |
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A local potential that is initiated by stimulation at a synapse, can vary in amplitude, and spreads passively across the cell membrane, decreasing in strength with time and distance |
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In chemistry, the point at which all ongoing reactions are canceled or balanced by others, resulting in a stable, offset, or unchanging system. |
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A reduction in membrane potential (the interior of the neuron becomes less negative). |
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The property of a membrane that allows some substances to pass through, but not others. |
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Transiently inactivated or exhausted. |
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The spontaneous spread of molecules of one substance among molecules of another substance until a uniform concentration is achieved |
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The structure of the neuronal cell membrane, which consists of two layers of lipid molecules, within which float various specialized proteins, such as receptors |
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Also called nerve impulse. The propagated electrical message of a neuron that travels along the axon to the presynaptic axon terminals |
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