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3 Periods of Cognitive Neuroscience |
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1) classical antiquity 2) medieval period 3) the modern era |
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Classical antiquity is known for: |
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Medieval Period is known for: |
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3-part model of cognition |
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relating mental processes to actual brain function |
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5 Important contributors to classical antiquity (in chronological order): |
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Ancient Egypt Alcmaeon (Greek physician) Hippocrates (Physician) Greek philosophy (Plato, Aristotle) Galen |
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Who was/were the first to name the brain and when? |
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the ancient egyptians circa 1700 BC |
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What did the egyptians think the brain's function was? |
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To supply mucus to the nose. (brain was removed during mummification... cuz we don't need mucus in the afterlife?? haha) |
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Where did the egyptians think mental processes took place? |
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What 2 things are important about the Edwin Smith surgical papyrus? |
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1) contained a hieroglyph for 'brain' (which is the basis for the claim that the egyptians were the first to name the brain) 2) believed to be the first medical document |
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Who is considered the first neuroscientist and when was this person alive? |
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Who was Alcmaeon a student of? |
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Who, from the antiquity period, used dissection for intellectual inquiry? |
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Which nerve did Alcmaeon study and what did he describe it as? |
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The optic nerve; described it as a light bearing path |
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What is the brain hypothesis (from antiquity period)? |
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"the brain is the site of sensation and cognition" |
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Who came up with the brain hypothesis? |
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Who supported the brain hypothesis besides Alcmaeon and when was this person alive? What was this person's occupation? |
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Hippocrates (460-370 BC) (he was a Greek physician) |
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Who came up with the tripartite theory of the soul? |
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What are the 3 parts of the tripartite theory of the soul? |
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In the tripartite theory of the soul, what is the brain responsible for? |
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In the tripartite theory of the soul, what is the heart responsible for? |
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anger, fear, pride and courage |
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In the tripartite theory of the soul, what is the liver responsible for? |
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lust, greed, desire, and 'lower' passions |
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Aristotle was a disciple of ______ and was alive around __________. |
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What MAIN view did Aristotle hold regarding the heart and from whom did he borrow this idea? |
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Heart is the organ of the soul (borrowed from the egyptians) |
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Besides being the organ of the soul what other 3 things did Aristotle believe about the heart? |
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1) centrally located in teh body 2) beating throughout life 3) it is warm |
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What did Aristotle think was the function of the brain? |
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to cool the blood and regulate the heart's temperature |
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Dissection was briefly popular during the antiquity period but then disappeared until _____________. What important discovery was made during this brief period of popularity? |
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1) the 13th century 2) the anatomy of the ventricles |
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The ventricles in the brain are filled with __________ and the 4 ventricles are named: 1) 2) 3) 4) |
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- cerebrospinal fluid 1) right lateral ventricle 2) left lateral ventricle 3) third ventricle 4) fourth ventricle |
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What other 3 features of the brain's anatomy are relevant to the ventricle system? |
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1) cerebral aqueduct 2) choroid plexus 3) central canal |
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Have you sufficiently studied and understood the ventricle diagram on slide 8 of lecture 1? |
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Which 2 types of people did the doctor Galen work with? Where was he from? When was he around? |
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- gladiators during the Roman Empire & was a surgeon for the emperors - from Pergamon - around 129-217 AD |
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Where did Galen locate the soul? What did he think was important about the ventricles? |
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soul = in solid portion of the brain ventricles = critical to the psyche/spirit |
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Who recognized that sense organs could be intact but sensation lost? What other important distinction did this person make? |
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Galen, who made the distinction between sensory and motor nerves. |
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What time period is considered the medieval period and what was the hallmark of this period? |
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Roughly the 4th - 14th centuries Hallmark: no dissection |
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What were the 2 main ideas about the brain/mind/etc during the medieval period? |
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- retention of the tripartite theory of the soul - the ventricles house the soul/mind (view was popular til ~16th century) |
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Which workis the following quotation from: "Tell me where is fancy bred, or in the heart, or in the head? |
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'The Merchant of Venice' by Shakespeare (circa 1600) |
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During which era was the tripartite theory finally abandoned? |
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3 important hallmarks of the modern era include: 1) Gradual movement toward _______________ 2) Birth of __________ 3) Invention of ___________ |
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1) Gradual movement toward: associating mental processes with fxn of brain structures 2) Birth of: experimental psychology 3) Invention of: brain imaging methods |
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Give the name, country, and years of life of the person who thought ventricles could not be the seat of higher mental fxns since animals had them but did not have the intellectual faculties of the soul. |
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Andreas Vesalius Belgian anatomist 1514-1564 |
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Rene Descartes: Thought cognition was interaction between ___ & ___ The ___ modifies behavior via its effects on ______. Dualism means: ____ |
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ventricles & pineal gland soul, pineal gland mind is 'separate' from the brain |
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Why was the pineal gland so central to the beliefs of Descartes? (2 reasons) |
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1) it seemed to be only brain organ not bilaterally duplicated 2) erroneously thought it was uniquely human |
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What is the Circle of Willis? Who discovered it and where were they from? |
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It's a circle of arteries that supply blood to the brain. Disc. by Thomas Willis of England (1621-1675) |
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What other important thing did Thomas Willis do besides discovering the circle of willis? |
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Spelled out a role for the cerebral cortex in higher cognition (especially memory) |
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Franz Gall and Johann Spurzheim were famous for which field? |
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Principles of Phrenology: - The ____ is the organ of the ____. - The ____ of various 'sections' of the brain determine the ____ of the ability localized to that section - Section sizes could be determined by bumps in the ______. |
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the brain is the organ of the mind size, strength SKULL (note that there is a distinction btw skull & brain) |
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2 good things about phrenology |
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- brought attn. to brain as enabler of mind - idea of functions being localized to certain regions |
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2 bad things about phrenology |
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- the idea that the size of an organ is a measure of its power - the idea that the skull is an accurate indicator of any mental ability |
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Opposition to Localization Known as: Led by: Theoretical rationale: Experimental rationale: |
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Holism Pierre Flourens Soul is unitary so dividing up the mind = denial of soul In experiments, birds recovered from brain lesion regardless of location of lesion |
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Holism Ct'd into 20th century Led by: Experimental rationale: His official stance/philosophy: |
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Karl Lashley rats w/ circumscribed lesions learn mazes same as w/o stance: Equipotentiality (diff. brain parts have equal potential to perform diff. fxns) |
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brain of 'Tan' - speech loss after lesion in left frontal cortex |
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comprehension loss after lesion in left temporal cortex |
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Implications of Broca/Wernicke discoveries: - _____ of ____ mental functions - focus on physiological functions like ___ vs. ___ instead of dumb stuff like 'the good mother fxn' - dominance of the part of the brain called the ______ |
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localization of higher mental functions motor vs. sensory cerebrum |
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Important things about ____ Jackson: - orderly progression of jerks across body during seizure suggests _____ _____. - RH lesions affect _____ functions - Not entirely localizationist: believed in ______ organization & ____ between regions. |
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John [Hughlings] Jackson topographic organization visuospatial hierarchical, interaction |
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What big discovery did Wilder Penfield make and what map did he develop based on this? |
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discovered that stimulating diff brain parts = diff. responses developed map of motor cortex (AKA motor homunculus) |
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What is cytoarchitectonics? |
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study of diff.s in cortical layers between brain areas |
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Brodmann's areas had how many subdivisions? His divisions were based on _____. Are monkey and human areas homologous? |
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52 cytoarchitectonics not necessarily NOTE: MORE RECENT SCHEMES USE HIS AREAS BUT SUBDIVIDE THEM FURTHER |
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Slide 32 .O {color:black; font-size:149%;} a:link {color:#CCCCFF !important;} a:active {color:#3333CC !important;} a:visited {color:#B2B2B2 !important;} Any given complex ability, then, is not accomplished by a single part of the brain. So in this sense the globalists were right. Slide 32 .O {color:black; font-size:149%;} a:link {color:#CCCCFF !important;} a:active {color:#3333CC !important;} a:visited {color:#B2B2B2 !important;} However, simple processes that are recruited to exercise such abilities are localized. So in this sense, the localizationists were right.” Who said this?
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What did Helmholtz study about frogs? |
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velocity of nerve conduction |
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How did Helmholtz conclude that vision is an 'unconscious inference' based on interaction btw current stimulus and past knowledge? |
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Humans wearing distorting prisms can adapt quickly and respond to the visual world normally |
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Who pioneered the measurement of the speed of mental operations and through what method? |
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Donders subtraction method (subtract time to detect single event from time to detect same event with 2 items present) |
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Which 3 guys were involved in the 'birth' of experimental psychology? Which century? |
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Wilhelm Wundt, William Jones, Hermann Ebbinghaus 19th century |
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Who had the 1st experimental psychology lab? What did it study? |
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Wilhelm Wundt 'conscious experience': perception, attn., memory |
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Behaviorism arose partly as a reaction to: |
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Wilhelm Wundt's lab's heavy reliance on subject's introspection |
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Who wrote 'Principles of Psychology'? What's the difference between functions and specific responses? |
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William Jones functions like perceiving recalling, or thinking persist, while specific responses depend on the situation |
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Hermann Ebbinghaus studied - memory without ___ - learning of ______ _______ - backward and forward ________ |
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-introspection nonsense syllables interference |
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Behaviorism (? - ?) was known as: |
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1910s - 1950s the Dark Ages |
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Under behaviorism what were the only valid subjects for psychological study? (2) What was not valid? |
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stimulus-response associations & overt behavior introspection was not valid under behaviorism |
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John Watson is associated with which period in the history of this field? |
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Behaviorism (the Dark Ages) |
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When was the cognitive revolution? How did it propose to measure cognition? |
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late 1950s by decomposing behavior |
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What inspired the cognitive revolution? (2) |
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-advent of computers -interest in artificial intelligence |
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Who came up with the 7 +/- 2 short-term memory capacity? During which period? |
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George Miller Cognitive revolution |
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Noam Chomsky argued that you can't explain comprehension with stimulus-response associations because... |
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How did Noam Chomsky think we learn language? |
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by abstracting the general rules of grammar |
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Who wrote 'Perception and Communication' and what 3 topics did it focus on? |
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Donald Broadbent -limited capacity -filtering -serial processing |
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From the 50s to late 70s there was little ______ between these 3 fields. |
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interaction - cognitive psychology - neuroscience - neuropsychology |
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Cognitive psychology definition: _________. (Interest in _____, _______ didn't matter) |
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can study mind without the brain software, hardware |
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Neuroscience definition: ______. (Little study of ________ with animal's ________.) |
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study of basic sensation correlation, behavior |
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Neuropsychology definition: ______. (Other disciplines unaware of efforts until early 80s) |
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As cognitive neuroscience emerged, it was a new field to study 'how the brain _______ the ______.' This quotation is from: |
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enables the mind Gazzaniga & Miller |
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Emerging field of cog. neuroscience emphasized multiple levels of ________, including these 3: 1) 2) 3) |
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analysis cellular systems behavioral |
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These advances in brain imaging technology facilitated the emergence of cognitive neuroscience (4) |
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- EEG -PET, fMRI, optical imaging - TMS - measuring brain-behavior relationships |
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Define each of these 3 technology advances that helped cognitive neuroscience emerge: -EEG -PET, fMRI, optical imaging -TMS |
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-electrical recordings of brain activity -brain imaging methods -temporary lesions |
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Who called the 90s the decade of the brain? |
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