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Psych 345 Lecture 1
Brief History of Coginitive Neuroscience
84
Psychology
Undergraduate 3
02/10/2009

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Term
3 Periods of Cognitive Neuroscience
Definition

1) classical antiquity

2) medieval period

3) the modern era

Term
Classical antiquity is known for:
Definition
localization of the soul
Term
Medieval Period is known for:
Definition
3-part model of cognition
Term
Modern era is known for:
Definition
relating mental processes to actual brain function
Term
5 Important contributors to classical antiquity (in chronological order):
Definition

Ancient Egypt

Alcmaeon (Greek physician)

Hippocrates (Physician)

Greek philosophy (Plato, Aristotle)

Galen

Term
Who was/were the first to name the brain and when?
Definition
the ancient egyptians circa 1700 BC
Term
What did the egyptians think the brain's function was?
Definition

To supply mucus to the nose.

 

(brain was removed during mummification... cuz we don't need mucus in the afterlife?? haha)

Term
Where did the egyptians think mental processes took place?
Definition
In the heart
Term
What 2 things are important about the Edwin Smith surgical papyrus?
Definition

1) contained a hieroglyph for 'brain'

(which is the basis for the claim that the egyptians were the first to name the brain)

 

2) believed to be the first medical document

Term
Who is considered the first neuroscientist and when was this person alive?
Definition
Alcmaeon, circa 450 BC
Term
Who was Alcmaeon a student of?
Definition
Pythagorus
Term
Who, from the antiquity period, used dissection for intellectual inquiry?
Definition
Alcmaeon
Term
Which nerve did Alcmaeon study and what did he describe it as?
Definition
The optic nerve; described it as a light bearing path
Term
What is the brain hypothesis (from antiquity period)?
Definition
"the brain is the site of sensation and cognition"
Term
Who came up with the brain hypothesis?
Definition
Alcmaeon
Term

Who supported the brain hypothesis besides Alcmaeon and when was this person alive?

 

What was this person's occupation?

Definition

Hippocrates (460-370 BC)

 

(he was a Greek physician)

Term
Who came up with the tripartite theory of the soul?
Definition
Plato and Democritus
Term
What are the 3 parts of the tripartite theory of the soul?
Definition

Brain

Heart

Liver

Term
In the tripartite theory of the soul, what is the brain responsible for?
Definition
intellect
Term
In the tripartite theory of the soul, what is the heart responsible for?
Definition
anger, fear, pride and courage
Term
In the tripartite theory of the soul, what is the liver responsible for?
Definition
lust, greed, desire, and 'lower' passions
Term
Aristotle was a disciple of ______ and was alive around __________.
Definition
Plato, 384 BC
Term
What MAIN view did Aristotle hold regarding the heart and from whom did he borrow this idea?
Definition
Heart is the organ of the soul (borrowed from the egyptians)
Term
Besides being the organ of the soul what other 3 things did Aristotle believe about the heart?
Definition

1) centrally located in teh body

2) beating throughout life

3) it is warm

Term
What did Aristotle think was the function of the brain?
Definition
to cool the blood and regulate the heart's temperature
Term
Dissection was briefly popular during the antiquity period but then disappeared until _____________.  What important discovery was made during this brief period of popularity?
Definition

1)  the 13th century

2)  the anatomy of the ventricles

Term

The ventricles in the brain are filled with __________ and the 4 ventricles are named:

 

1)

2)

3)

4)

 

 

Definition

- cerebrospinal fluid

 

1) right lateral ventricle

2) left lateral ventricle

3) third ventricle

4) fourth ventricle

 

Term
What other 3 features of the brain's anatomy are relevant to the ventricle system?
Definition

1) cerebral aqueduct

2) choroid plexus

3) central canal

 

Term
Have you sufficiently studied and understood the ventricle diagram on slide 8 of lecture 1?
Definition
[image]
Term

Which 2 types of people did the doctor Galen work with?

Where was he from?

When was he around?

Definition

- gladiators during the Roman Empire & was a surgeon for the emperors

- from Pergamon

- around 129-217 AD

Term

Where did Galen locate the soul?

What did he think was important about the ventricles?

Definition

soul = in solid portion of the brain

ventricles = critical to the psyche/spirit

Term

Who recognized that sense organs could be intact but sensation lost?

What other important distinction did this person make?

Definition
Galen, who made the distinction between sensory and motor nerves.
Term
What time period is considered the medieval period and what was the hallmark of this period?
Definition

Roughly the 4th - 14th centuries

Hallmark:  no dissection

Term
What were the 2 main ideas about the brain/mind/etc during the medieval period?
Definition

- retention of the tripartite theory of the soul

 

- the ventricles house the soul/mind

 (view was popular til ~16th century)

Term

Which workis the following quotation from:

"Tell me where is fancy bred, or in the heart, or in the head?

Definition

'The Merchant of Venice'

by Shakespeare

 

(circa 1600)

Term
During which  era was the tripartite theory finally abandoned?
Definition
the modern era
Term

3 important hallmarks of the modern era include:

 

1) Gradual movement toward _______________

 

2) Birth of __________

 

3) Invention of ___________

Definition

1) Gradual movement toward:  associating mental processes with fxn of brain structures

 

2) Birth of: experimental psychology

 

3) Invention of: brain imaging methods
Term
Give the name, country, and years of life of the person who thought ventricles could not be the seat of higher mental fxns since animals had them but did not have the intellectual faculties of the soul.
Definition

Andreas Vesalius

 

Belgian anatomist

 

1514-1564

Term

Rene Descartes:

 

Thought cognition was interaction between ___ & ___

 

The ___ modifies behavior via its effects on ______.

 

Dualism means: ____

Definition

ventricles & pineal gland

 

soul, pineal gland

 

mind is 'separate' from the brain

Term
Why was the pineal gland so central to the beliefs of Descartes? (2 reasons)
Definition

1) it seemed to be only brain organ not bilaterally duplicated

 

2) erroneously thought it was uniquely human

 

Term
What is the Circle of Willis? Who discovered it and where were they from?
Definition

It's a circle of arteries that supply blood to the brain.

 

Disc. by Thomas Willis of England (1621-1675)

Term
What other important thing did Thomas Willis do besides discovering the circle of willis?
Definition

Spelled out a role for the cerebral cortex in higher cognition (especially memory)

 

Term
Franz Gall and Johann Spurzheim were famous for which field?
Definition
Phrenology
Term

Principles of Phrenology:

 

- The ____ is the organ of the ____.

 

- The ____ of various 'sections' of the brain determine the ____ of the ability localized to that section

 

- Section sizes could be determined by bumps in the ______.

Definition

the brain is the organ of the mind

 

size, strength

 

SKULL (note that there is a distinction btw skull & brain)

 

Term
2 good things about phrenology
Definition

- brought attn. to brain as enabler of mind

 

- idea of functions being localized to certain regions

Term
2 bad things about phrenology
Definition

- the idea that the size of an organ is a measure of its power

 

- the idea that the skull is an accurate indicator of any mental ability

Term

Opposition to Localization

 

Known as:

Led by:

Theoretical rationale:

Experimental rationale:

Definition

Holism

 

Pierre Flourens

 

Soul is unitary so dividing up the mind = denial of soul

 

In experiments, birds recovered from brain lesion regardless of location of lesion

Term

Holism Ct'd into 20th century

 

Led by:

 Experimental rationale:

 

His official stance/philosophy:

Definition

Karl Lashley

 

rats w/ circumscribed lesions learn mazes same as w/o

 

stance: Equipotentiality (diff. brain parts have equal potential to perform diff. fxns)

 

Term
Broca's area is for
Definition
speech production
Term
Wernicke's area is for
Definition
speech comprehension
Term
Broca's evidence:
Definition
brain of 'Tan' - speech loss after lesion in left frontal cortex
Term
Wernicke's evidence:
Definition
comprehension loss after lesion in left temporal cortex
Term

Implications of Broca/Wernicke discoveries:

 

- _____ of ____ mental functions

- focus on physiological functions like ___ vs. ___ instead of dumb stuff like 'the good mother fxn'

- dominance of the part of the brain called the ______

Definition

localization of higher mental functions

 

motor vs. sensory

 

cerebrum

Term

Important things about ____ Jackson:

 

- orderly progression of jerks across body during seizure suggests _____  _____.

 

- RH lesions affect _____ functions

 

- Not entirely localizationist: believed in ______ organization & ____ between regions.

Definition

John [Hughlings] Jackson

 

topographic organization

 

visuospatial

 

hierarchical, interaction

Term
What big discovery did Wilder Penfield make and what map did he develop based on this?
Definition

discovered that stimulating diff brain parts = diff. responses

 

developed map of motor cortex (AKA motor homunculus)

 

Term
What is cytoarchitectonics?
Definition
study of diff.s in cortical layers between brain areas
Term

Brodmann's areas had how many subdivisions?

His divisions were based on _____.

Are monkey and human areas homologous?

Definition

52

cytoarchitectonics

not necessarily

 

NOTE: MORE RECENT SCHEMES USE HIS AREAS BUT SUBDIVIDE THEM FURTHER

Term
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Any given complex ability, then, is not accomplished by a single part of the brain. So in this sense the globalists were right.
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However, simple processes that are recruited to exercise such abilities are localized. So in this sense, the localizationists were right.”
 
Who said this?
Definition
Kosslyn & Andersen
Term
What did Helmholtz study about frogs?
Definition
velocity of nerve conduction
Term
How did Helmholtz conclude that vision is an 'unconscious inference' based on interaction btw current stimulus and past knowledge?
Definition
Humans wearing distorting prisms can adapt quickly and respond to the visual world normally
Term
Who pioneered the measurement of the speed of mental operations and through what method?
Definition

Donders

 

subtraction method

(subtract time to detect single event from time to detect same event with 2 items present)

Term

Which 3 guys were involved in the 'birth' of experimental psychology?

 

Which century?

Definition

Wilhelm Wundt, William Jones, Hermann Ebbinghaus

 

19th century

Term

Who had the 1st experimental psychology lab?

What did it study?

 

Definition

Wilhelm Wundt

'conscious experience': perception, attn., memory

Term
Behaviorism arose partly as a reaction to:
Definition
Wilhelm Wundt's lab's heavy reliance on subject's introspection
Term

Who wrote 'Principles of Psychology'?

 

What's the difference between functions and specific responses?

Definition

William Jones

 

functions like perceiving recalling, or thinking persist, while specific responses depend on the situation

Term

Hermann Ebbinghaus studied

 

- memory without ___

- learning of ______  _______

 - backward and forward ________

Definition

-introspection

nonsense syllables

interference

Term
Behaviorism (? - ?) was known as:
Definition

1910s - 1950s

 

the Dark Ages

Term

Under behaviorism what were the only valid subjects for psychological study? (2)

 

What was not valid?

Definition

stimulus-response associations

&

overt behavior

 

introspection was not valid under behaviorism

Term
John Watson is associated with which period in the history of this field?
Definition
Behaviorism (the Dark Ages)
Term

When was the cognitive revolution?

How did it propose to measure cognition?

 

Definition

late 1950s

by decomposing behavior

Term
What inspired the cognitive revolution? (2)
Definition

-advent of computers

-interest in artificial intelligence

Term

Who came up with the 7 +/- 2 short-term memory capacity?

 

During which period?

Definition

George Miller

 

Cognitive revolution

 

Term
Noam Chomsky argued that you can't explain comprehension with stimulus-response associations because...
Definition
most sentences are new
Term
How did Noam Chomsky think we learn language?
Definition
by abstracting the general rules of grammar
Term
Who wrote 'Perception and Communication' and what 3 topics did it focus on?
Definition

Donald Broadbent

 

-limited capacity

-filtering

-serial processing

 

Term
From the 50s to late 70s there was little ______ between these 3 fields.
Definition

interaction

 

- cognitive psychology

- neuroscience

- neuropsychology

Term

Cognitive psychology definition: _________.

 

(Interest in _____, _______ didn't matter)

Definition

can study mind without the brain

 

software, hardware

 

Term

Neuroscience definition: ______.

 

(Little study of ________ with animal's ________.)

Definition

study of basic sensation

 

correlation, behavior

 

Term

Neuropsychology definition: ______.

 

(Other disciplines unaware of efforts until early 80s)

Definition
studying mind AND brain
Term

As cognitive neuroscience emerged, it was a new field to study 'how the brain _______ the ______.'

 

This quotation is from:

Definition

enables the mind

 

Gazzaniga & Miller

Term

Emerging field of cog. neuroscience emphasized multiple levels of ________, including these 3:

 

1)

2)

3)

 

Definition

analysis

 

cellular

systems

behavioral

 

Term
These advances in brain imaging technology facilitated the emergence of cognitive neuroscience (4)
Definition

- EEG

-PET, fMRI, optical imaging

- TMS

- measuring brain-behavior relationships

Term

Define each of these 3 technology advances that helped cognitive neuroscience emerge:

 

-EEG

-PET, fMRI, optical imaging

-TMS

Definition

-electrical recordings of brain activity

-brain imaging methods

-temporary lesions

 

Term
Who called the 90s the decade of the brain?
Definition
George Bush Sr.
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