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Proteins, Vitamins, Antioxidants
Functions, Toxicities, Deficiencies
192
Health Care
Undergraduate 2
10/21/2012

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Cards

Term
What is a precursor of Vitamin A?
Definition
Beta-carotene
Term
What are the three forms of Vitamin A in the body?
Definition
Retinol Retinal Retinoic Acid
Term
Where is retinol stored?
Definition
Liver
Term
What are the functions of Vitamin A?
Definition
Vision: Cornea, Epithelial Cells, Mucous Membrane Skin Bone & Tooth Growth Regulation of Gene Expression Reproduction Immunity
Term
What are the effects of a Vitamin A Deficiency?
Definition
Night Blindness Corneal Drying (xerosis) Blindness (xerophthalmia) Impaired Bone Growth/Tooth Decay Keratin Lumps on Skin Impaired Immunity
Term
What are the effects of a Vitamin A Toxicity?
Definition
Increased Activity of Osteoclasts Liver Abnormalities Birth Defects Harmless Yellowing of Skin
Term
How does Vitamin A regulate Genes?
Definition
With Retinoic Acid
Term
What are 2 indispensable roles of Vitamin A with eyesight?
Definition
Process of Light Perception at Retina
Maintenance of Healthy Cornea
Term
What is rhodopsin?
Definition
Light-sensitive Pigment of Retina Cells
Term
What is Keratin?
Definition
Normal Protein of Hair and Nails
Term
What is Keratinization?
Definition
Accumulation of Keratin in a Tissue
Sign of Vitamin A Deficiency
Term
What is Xerophthalmia?
Definition
Progressive hardening of cornea of eye that can lead to blindness
Term
Main Food Sources of Vitamin A
Definition
Liver Oil
Fish Oil
Term
Where does Beta-carotene exists?
Definition
Plants
Term
What is Macular Degeneration?
Definition
Progressive loss of function to part of the retina that is crucial to focused vision
Leads to Blindness
Term
What are food sources of Beta-carotene?
Definition
Orange Fruits & Vegetables
Dark Green Vegetables
Term
What are the fat-soluble vitamins?
Definition
Vitamins A, D, E, K
Term
What are the dietary antioxidants?
Definition
Vitamin E, Vitamin C, Selenium, Beta-carotene
Term
What is the toxicity of Beta-carotene?
Definition
None, harmless skin yellowing
Term
What substance breaks down polypeptides in the small intestine?
Definition
Protease
Term
What is the portion of an amino acid that contains nitrogen called?
Definition
Amine Group
Term
What do proteins contain?
Definition
Carbon
Oxygen
Nitrogen
Hydrogen
Term
What vitamin is destroyed by heat exposure and oxidation?
Definition
Vitamin E
Term
What is oxidation
Definition
An atom loses an electron
Term
What disorder is linked with free radicals?
Definition
Cardiovascular Disease
Term
What are known carcinogens?
Definition
Nitrates
Term
Taking daily doses of 3-4 times the RDA of what nutrient may cause death?
Definition
Vitamin A
Term
What are the B-complex Vitamins?
Definition
Thiamin, Pantothenic Acid, Biotin
Term
What is homocysteine?
Definition
Amino Acid
Term
What is necessary for the synthesis of phospholipids and other components of cell membranes?
Definition
Choline
Term
What are antioxidants?
Definition
Compounds in diet that work to prevent damage to cells and tissues
Term
What foods are rich in antioxidants?
Definition
They are rich in color. Ex: red delicious apple, dark chocolate, plums, red wine, blueberries, pecans
Term
What is a vitamin?
Definition
Essential, non-caloric, organic nutrient needed in small amounts in the diet
Term
Do vitamins give you energy?
Definition
No, they help you make energy
Term
What are the water-soluble vitamins?
Definition
Thiamin, Riboflavin, Niacin, Folate, Vitamin B12, Vitamin B6, Biotin, Panthothenic Acid, Vitamin C
Term
What are the B Vitamins?
Definition
Thiamin
Riboflavin
Niacin
Folate
Vitamin B12
Vitamin B6
Biotin
Panthothenic Acid
Term
Where is Retinyl Esters found?
Definition
Animal Foods
Term
What is the difference between primary and secondary deficiencies?
Definition
Primary=Don't eat enough
Secondary=Don't use what you're eating
Term
Where beta-carotene broken down?
Definition
Broken down in the small intestine to retinol (vitamin A)
Term
What is another name for Vitamin E?
Definition
Alpha-tocopherol
Term
What are the functions of Vitamin E?
Definition
Antioxidant
Protects Cell Membrane
Regulates Oxidation Reactions
Protects Polyunsaturated Fatty Acids
Term
What are the effects of Vitamin E deficiency?
Definition
Red Blood Cell Breakage
Nerve Damage
Loss of Muscle Coordination
Term
What are the effects of Vitamin E toxicity?
Definition
Augments effects of anti-clotting medication
Term
What are free radicals?
Definition
Atoms/molecules with an unpaired electron that make it unstable or highly reactive
Term
What is erythrocyte hemolysis?
Definition
Rupture of red blood cells, Cause by Vitamin E deficiency
Term
What are food sources of Vitamin E?
Definition
Canola Oil
Safflower Oil
Sunflower Seeds
Wheat Germ
Term
Where is Vitamin E absorbed?
Definition
From the intestines like fat via the lymph
Term
What is another name for Vitamin C?
Definition
Ascorbic Acid
Term
What are the functions of Vitamin C?
Definition
Collagen Synthesis
Antioxidant
Restores Vitamin E to Active Form
Supports Immune System
Boosts Iron Absorption
Term
What are the effects of Vitamin c Deficiency?
Definition
Scurvy
Hemorrhages
Fatigue
Bleeding Gums
Bruises
Bone Fragility
Joint Pain
Poor Wound Healing
Frequent Infections
Term
What is Vitamin C Toxicity?
Definition
Nausea
Abdominal Cramps
Diarrhea
Rashes
Interference with Medical Tests and Drug Therapies
Aggravation of Kidney Stones
Term
What are the functions of Collagen?
Definition
Forms Base for Connective Tissues
Forms Scar Tissue that Heals Wounds
Reinforce Structure that Mends Fractures
Supports Material of Capillaries that Prevents Bruises
Term
What vitamin do the enzymes involved in the formation and maintenance of the protein collagen depend on?
Definition
Vitamin C
Term
What is a prooxidant?
Definition
Compound that triggers reactions involving oxygen
Term
What are incomplete proteins?
Definition
Don't have all 9 amino acids
Term
What are complete proteins?
Definition
Have all 9 amino acids
Term
What happens if one amino acid is lacking?
Definition
Protein synthesis stops
Term
Where does protein digestion begin?
Definition
Stomach
Term
What does MNRA do?
Definition
Messenger RNA
Term
What does TNRA do?
Definition
Transfer RNA, puts them in order
Term
What breaks down protein?
Definition
Proteases
Term
What hormone puts calcium back in bones?
Definition
Calcitonin
Term
What hormone takes calcium from bones and puts it in the bloodstream?
Definition
PTH
Term
What is calcium DRI?
Definition
Men 90mg Women 75mg Smokers 125mg/110mg
Term
What causes Rickets in children?
Definition
Vitamin D deficiency
Term
What are Osteoblasts?
Definition
Build new bone
Term
What are Osteoclasts?
Definition
Breakdown old bone
Term
What are Food Sources of Vitamin C?
Definition
Peppers, Citrus, Broccoli, Brussels Sprouts, Strawberries
Term
Where is Vitamin C stored?
Definition
In small amounts all around the body
Term
Which vitamin is most easily destroyed?
Definition
Vitamin C
Term
How can Vitamin C be destroyed?
Definition
Heat and Air Exposure
Term
How does Vitamin C prevent anemia?
Definition
Converts inactive form, folic acid, to active form, folinic acid, inside cells
Term
What vitamin does Vitamin C help regenerate by giving it an electron?
Definition
Vitamin E
Term
What are the Functions of Selenium?
Definition
Protects Against Oxidation
Essential for thyroid hormones that regulate metabolism
Term
What are Food Sources of Selenium?
Definition
Seafoods
Meats
Whole Grain
Vegetables
Term
What are the Selenium deficiency effects?
Definition
Muscle Disorders
Weakness
Pain
Specific Heart Diseases
Term
What is Selenium toxicity?
Definition
Nausea
Abdominal Pain
Hair Loss
Nerve, Liver, Muscle Damage
Term
What vitamin does Selenium work with?
Definition
Vitamin E
Term
What hormone does Selenium activate?
Definition
Thyroxin
Term
What vitamin is essential for collagen formation?
Definition
Vitamin C
Term
What is Beriberi?
Definition
Thiamin Deficiency
Characterized by Edema (Fluid)
Term
Functions of Thiamin
Definition
Energy Metabolism
Nerve Cells
Term
Thiamin Deficiencies
Definition
Beriberi
Enlarged Heart/Failure
Muscular Weakness/Pain/Apathy
Confusion
Anorexia/Weight Gain
Term
Food Sources of Thiamin
Definition
Whole Wheat
Enriched Food
Pork Chop
Sunflower Seeds
Green Peas
Term
Functions of Riboflavin
Definition
Energy Metabolism
Term
Food Sources of Riboflavin
Definition
Dairy
Beef
Enriched Foods
Pork Chop
Mushrooms
Spinach
Term
Toxicity of Thiamin
Definition
None
Term
Deficiencies of Riboflavin
Definition
Cracks/Redness at Mouth
Red/Smooth Tongue
Inflamed Eyes
Skin Rashes
Term
Toxicity of Riboflavin
Definition
None
Term
What is Pellagra?
Definition
Niacin Deficiency
Symptoms Include 4 D's
Diarrhea
Dermatitis
Dementia
Death
Term
Food Sources of Niacin
Definition
Chicken
Tuna
Pork
Enriched Cereal
Term
Function of Niacin
Definition
Energy Metabolism
Term
Deficiencies of Niacin
Definition
Pellagra
Skin Rash
Depression
Apathy
Fatigue
Memory Loss
Term
Toxicity of Niacin
Definition
Blushing
Sweating
Headaches
Hives
Blurred Vision
Term
What vitamin can be created by the amino acid tryptophan?
Definition
Niacin
Term
Food Sources of Folate
Definition
Liver
Lentils
Beans
Spinach
Asparagus
Term
Function of Folate
Definition
New Cell Synthesis
Synthesize DNA
Term
Deficiencies of Folate
Definition
Anemia
Smooth Tongue
Depression
Confusion
Neural Tube Defects
Term
Toxicity of Folate
Definition
None
Term
What is Pernicious Anemia?
Definition
Vitamin B12 deficiency
Lack of intrinsic factor
Characterized by large, immature red cells
Damage to nerve system
Term
Food Sources of B12
Definition
Liver
Sardines
Steak
Tuna
Cheese
Term
Functions of B12
Definition
New Cell Synthesis
Maintain Nerve Cells
Term
Deficiencies of B12
Definition
Pernicious Anemia
Nerve Damage
Term
Toxicity of B12
Definition
None
Term
Food Sources of B6
Definition
Liver
Potatoes
Spinach
Banana
Chicken
Term
Functions of B6
Definition
Amino Acid/Fatty Acid Metabolism
Converts Tryptophan to Niacin & Serotonin
Helps Make Hemoglobin
Term
Deficiencies of B6
Definition
Anemia
Depression
Confusion
Abnormal Brain Waves
Convulsions
Greasy-Scaly Dermatitis
Term
Toxicity of B6
Definition
Depression
Fatigue
Impaired Memory
Irritability
Nerve Damage
Muscle Weakness
Term
Food Sources for Calcium
Definition
Sardines
Dairy
Tofu
Waffles
Broccoli
Turnips
Term
Functions of Calcium
Definition
Bones & Teeth
Muscle Contraction/Relaxation
Blood Clotting
Nerves
Term
Deficiencies of Calcium
Definition
Stunted Growth, Weak Bones, Bone Loss
Term
Toxicity of Calcium
Definition
Constipation
Kidney Stones
Hinder Other Mineral Absorption
Term
Food Sources of Phosphorus
Definition
Cheese
Salmon
Milk
Steak
Navy Beans
Term
Functions of Phosphorus
Definition
Bones & Teeth
Part of Phospholipids
DNA
Energy Metabolism
Buffering Systems
Term
Deficiencies of Phosphorus
Definition
Muscular Weakness
Bone Pain
Term
Toxicity of Phosphorus
Definition
Calcification of Soft Tissues
Term
Food Sources of Vitamin K
Definition
Cauliflower
Cabbage
Canola Oil
Spinach
Greens
Soybeans
Term
Functions of Vitamin K
Definition
Clots Blood
Build Bone Protein
Term
Deficiencies of Vitamin K
Definition
Hemorrhage
Abnormal Bone Formation
Term
Toxicity of Vitamin K
Definition
Jaundice
Counteracts Anti-Clotting Medication
Term
Functions of Carnitine
Definition
Metabolism Helper
Term
Functions of Inositol
Definition
Makes Neurotransmitter
Term
Food Sources of Inositol
Definition
Fiber Foods
Term
Food Sources of Lipoic Acid
Definition
Everything
Term
Functions of Lipoic Acid
Definition
Antioxidants
Glucose Metabolism
Insulin Resistance Decreaser
Term
Calcium DRI
Definition
19-50 yr 1000mg
>51yr 1200mg
Term
Folate DRI
Definition
400ug
Term
How can Riboflavin be destroyed?
Definition
Ordinary Light
Term
DRI for Vitamin D
Definition
19-50yr 5ug
51-70yr 10ug
>70yr 15ug
Term
What are Trace Minerals?
Definition
Essential mineral nutrients required in the diet in amounts less than 100mg/day. Microminerals
Term
The most abundant mineral in the body
Definition
Calcium
Term
The second most abundant mineral in the body
Definition
Phosphorus
Term
What is Osteoporosis?
Definition
Adult Bone Loss
Bones Become Fragile and Porous
Easily Broken
Hard Bone
Term
What is hydroxyapatite?
Definition
Chief Crystal of Bone
Formed From Calcium and Phosphorus
Term
What is Osteomalacia?
Definition
Softening of Long Bones
Caused by Depletion of Bone Stores of Calcium & Phosphorus
Soft Bones
Term
Where is almost all of calcium stored?
Definition
Bones and Teeth
Term
What do calcium phosphate salts crystalize with to form a foundation for bone formation?
Definition
Collagen
Term
What is fluorapatite?
Definition
Crystal of Bones and Teeth
Formed when Fluoride Displaces the hydroxy Portion
It resists being dissolved back into body fluid
Term
Functions of Calcium in the body fluids
Definition
Regulates transport of ions across cell membrane
Nerve transmission
Maintain blood pressure
Blood Clotting
Muscle Contraction/Heartbeat
Secretions of Hormones, Digestive Enzymes, Neurotransmitters
Term
What serves as a bank for calcium?
Definition
The skeleton/bones
Term
Where is most of the Phosphorus stored?
Definition
Bones
Term
Functions of Phosphorus in the body
Definition
Maintain acid-base balance of cellular fluids
Essential for growth and renewal of tissues
Energy in Metabolism
Extract Energy From Nutrients
Term
Why do most Americans diets not have deficiencies in Phosphorus?
Definition
It is added to dark colas as a preservative
Term
What vitamin can be synthesized in the G.I. tract?
Definition
Vitamin K
Term
Where does most Calcium absorption occur?
Definition
Duodenum of Small Intestine
Term
What vitamin helps absorb Calcium?
Definition
Vitamin D
Term
What is Trabecular Bone?
Definition
Spongy Porous Bone
Supports Cortical Bone
More Easily Broken Down to use in the Body
Term
What is Cortical Bone?
Definition
Outside Part of Bones
Hard Bone
Term
What are amino acids?
Definition
Building Blocks of Protein
Amine Group at One End
Acid Group at the Other
Distinctive Side Chain
Term
What is an amine group?
Definition
Nitrogen containing portion of amino acid
Term
What is a side chain?
Definition
Unique chemical structure attached to backbone of each amino acid that makes them different
Term
What is a peptide bond?
Definition
Bond that connects amino acids to each other
Forms link in protein chains
Term
What is the second most plentiful structure in the body?
Definition
Protein
Term
What are the 9 Essential Amino Acids?
PVT TIM H(A)LL
Definition
Phenylalanine
Valine
Threonine
Tryptophan
Isoleucine
Methionine
Histidine
Lysine
Leucine
Term
Where are amino acids stored in the body?
Definition
Can't be stored
Term
What are Complementary Proteins?
Definition
Two or More Food Proteins Combined Together to Form Complete Proteins
EX: Grains & Cheese
Term
What 4 elements make up Proteins?
Definition
Hydrogen
Oxygen
Nitrogen
Carbon
Term
What element do some proteins contain?
Definition
Sulfur
Term
What are recycled amino acids used for?
Definition
Build New Proteins/Compounds
Be Catabolized for Energy in Body, If Lack glucose
Term
Functions of Proteins
Definition
Provide Structure to Cells
Muscle Contraction
Enzymes Reaction
Antibodies
Transport Vehicles (Lipoproteins)
Hormones (Messengers)
Cellular Pumps
Oxygen Carriers
Term
What structures do proteins make up?
Definition
Tendons
Ligaments
Scar Tissue
Fibers of Muscles
Bone & Teeth
Hair & Nails
Term
What are antibodies?
Definition
Proteins that defend against foreign proteins and substances that get in body fluid compartments
Term
What is a dipeptide?
Definition
Formation of a peptide bond between 2 amino acids
Term
What is Amphoteric?
Definition
Acts as acid or Base
Term
Where does protein digestion start?
Definition
Stomach
Term
How can proteins be denatured?
Definition
Heat
Radiation
Alcohol
Acids
Bases
Salts of Heavy Metal
Term
Where are amino acids absorbed?
Definition
Directly into Blood
Term
What denatures proteins in the stomach during digestion?
Definition
Stomach Acid
Term
What attacks peptide bonds in the stomach during digestion?
Definition
Enzymes
Term
What do the stomach enzymes do to the protein during digestion?
Definition
Splits Proteins into Polypeptides
Term
What are Polypeptides?
Definition
Protein Fragments of Many Amino Acids
Term
What Tripeptides?
Definition
Protein Fragments of Three Amino Acids
Term
What happens to proteins in the small intestine during digestion?
Definition
Pancreas & Intestine Enzymes Split Peptide Strands into tripeptides, dipeptides and amino acids
Then split amino acids to be absorbed into blood stream
Term
What happens to proteins once absorbed into bloodstream?
Definition
Transported to all body cells
Term
What enzyme in the stomach breaks down protein?
Definition
Protease (Pepsin)
Term
What is Hemoglobin?
Definition
Globular Protein found in red blood cells
Made of 4 associated protein strands
Each contain iron
Term
Function of hemoglobin
Definition
Carry oxygen from lungs to tissues
Term
What is protein turnover?
Definition
Continuous Breakdown/Synthesis of Body Proteins involving recycling amino acids
Term
Importance of Protein Turnover
Definition
Grow New Cells
Replace Worn-out Ones
Term
Sickle Cell Anemia
Definition
Has Inappropriate Amino Acids
Term
Functions of Trytophan
Definition
Makes Niacin & Tyrosine
Term
Functions of Serotonin
Definition
Chemical Messenger (Sleepy, Happy)
Vasoconstrictor
Term
What is a Lipoprotein?
Definition
Fat and Cholesterol Transport
Term
What is Tranferrin?
Definition
Iron Transport
Term
Conversion rate of pounds to kilograms
Definition
2.2 lbs=1kg
Term
How is the sequence of amino acids determined?
Definition
Heredity (DNA)
Term
What do you need for protein synthesis?
Definition
All Essential Amino Acids
Adequate Supply of Protein
Adequate Energy (Carbs & Fat)
Term
What is Kwashiorkor?
Definition
Protein Deficiency
Term
Symptoms of Kwashiorkor
Definition
Edema
Patchy Skin
Distended Stomach
Hair Loss
Decreased Appetite
Growth Failure
Term
What is Marasmus?
Definition
Protein & Calorie Deficiency
Term
Symptoms of Marasmus
Definition
Skin and Bone
Stop Growth
Poor Absorption
Term
What do enzymes do?
Definition
Speeds up reaction that will happen anyway
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