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Protein Synthesis & The Genetic Code OBSR Part 1
Protein Synthesis & The Genetic Code OBSR Class 13 Part 1 (Transcription)
24
Biology
Undergraduate 2
12/17/2010

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Term
Information encoded in __________ specifies the sequences of amino acids in proteins and it involves two vital processes - __________ & __________.
Definition
1) DNA
2) Transcription
3) Translation
Term
__________ -> __________ -> __________
Thus DNA is __________ to form RNA and mRNA is __________ to form a __________.
Definition
1) DNA -> RNA -> Protein
2) Transcribed
3) Translated
4) Polypeptide
Term
__________ and __________ demonstrated the relationship between genes and proteins in the 1940s.
Definition
1) Beadle and Tatum
Term
RNA is composed of:
-__________ sugar
-__________ (instead of thymine) with the other three remaining nucleotide bases: __________, __________, and __________.
-Subunits __________ (type of bond) joined by 5'-3' linkages to form alternating sugar __________ backbone.
-Three types:
++__________ or __________ __________
++__________ or __________ __________
++__________ or __________ __________
Definition
1) Ribose
2) Uracil
3) Adenine
4) Guanine
5) Cytosine
6) Covalently
7) Phosphate
8) mRNA or messenger RNA
9) rRNA or ribosomal RNA
10) tRNA or transfer RNA
Term
Is uracil a purine or pyrimidine base?
Definition
1) Uracil is a pyrimidine base
Term
Uracil forms a complementary base pair with which other base?
Definition
1) Adenine
Term
A __________ is a long chain of amino acids.
They function as __________, structural and storage proteins, __________, etc.
Definition
1) Protein
2) Enzymes
3) Hormones
Term
A __________ is three nucleotide bases which determine the order of amino acids in the protein.
The __________ is the complementary base pairing with the codon.
-Also possesses __________.
Definition
1) Codon
2) Anticodon
3) tRNA
Term
What is the start codon?
What are the three possible stop codons?
Definition
1) AUG
2) UAA, UGA, UAG
Term
In DNA, each protein is encoded by a __________ - a specific sequence of DNA nucleotides that specify how a single protein is to be made.
There are only __________ DNA bases but there are __________ possible amino acids that can be used for proteins.
A three (3) base codon thus yields __________ possible patterns and hence the genetic code is redundant.
Definition
1) Gene
2) Four (4)
3) Twenty (20)
4) 64
Term
__________ is the process of "copying" one kind of nucleic acid (__________) to another kind of nucleic acid (__________).
__________ -> __________
mRNA is produced in the __________ and then it moves to the __________ through the nuclear pores.
Definition
1) Transcription
2) DNA
3) RNA
4) DNA
5) mRNA
6) Nucleus
7) Cytoplasm
Term
The three phases of transcription are: __________, __________, and __________.
Definition
1) Initiation
2) Elongation
3) Termination
Term
In transcription, synthesis is __________ in which a particular strand may serve as the template strand for some __________ and the non-template strand for others.
Definition
1) Antiparallel
2) Genes
Term
In transcription, __________ is synthesized in the 5'-> 3' direction and the __________ __________ is read in the 3' -> 5' direction.
RNA synthesis does not require a __________.
As the nucleotide is added to the RNA or DNA molecule two of the __________ __________ are removed and hence the reaction is __________.
Definition
1) RNA
2) DNA template
3) Primer
4) Phosphate groups
5) Exergonic
Term
RNA produced at the end of transcription is __________ and it is produced in the __________ and moved to the cytoplasm through the __________ __________.
Definition
1) mRNA
2) Nucleus
3) Nuclear pores
Term
A certain template DNA strand has the following nucleotide sequence: 3'-TACTGCATAATGATT-5'
What would be the sequence of codons in the mRNA transcribed from this strand?
What would be the nucleotide sequence of the complementary non-template DNA strand?
Definition
1) 5'-AUGACGUAUUACUAA-3'
2) 5'-ATCACGTATTACTAA-3'
Term
One codon is equal to how many amino acids?
Definition
1) One (1)
Term
RNA is synthesized in __________ -> __________ direction and the DNA template is read in the __________ -> __________ direction.
Definition
1) 5' -> 3'
2) 3' -> 5'
Term
True or False: RNA does not require a primer.
Definition
1) True
Term
G on the DNA strand pairs with __________ on the RNA while T on the DNA pairs with __________ on the RNA but A on the DNA pairs with __________ on the RNA.
Definition
1) C
2) A
3) U
Term
Transcription refers most specifically to:
a. Replication of DNA
b. Synthesis of proteins
c. Synthesis of mRNA
d. Synthesis of amino acids
Definition
1) c. Synthesis of mRNA
Term
Is transcription an exergonic or endergonic reaction? Why?
Definition
1) Since two phosphate groups are removed when the nucleotide is added the reaction is exergonic.
Term
Which of the following cannot be found in an RNA molecule?
a. Ribose
b. Deoxyribose
c. Adenine
d. Uracil
e. Phosphate group
Definition
1) b. Deoxyribose sugar
Term
Each group of three nucleotide bases codes directly for an __________ __________.
Definition
1) Amino acid
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