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Principles II test II Patho-Endo slides 15-27
Would a moose knuckle be a synovial joint?
12
Nursing
Graduate
10/18/2009

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Term
What is a life-threatening exacerbation of hyperthyroidism that can occur under stress such as infection, surgery, or injury?
Definition
Thyroid Storm
Term
What are s/s of thyroid storm?
Definition
-hyperpyrexia

-tachycardia

-anxiety

-cardiovascular instability

-altered consciousness
Term
With thyroid storm, there is significant morbidity & tx is symptomatic.
Definition
That's all I have to say 'bout that...
Term
What are the MANY ways a pt can become euthyroid before surgery?
Definition
*Propylthiourcil & methimazole inhibit synthesis of thyroid hormone

*Propylthiouracil also decreases T4->T3 conversion in periphery

*Inorganic iodide inhibits thyroid hormone release and decreases hyperplasia

*B-blockers impairs conversion of T4 to T3 and decreases symptoms of tachycardia, aniety, heat intolerance
*glucocorticoids (dexamethasone) decreases thyroid hormone production

*radioactive iodine can treat thyroid storm
Term
How long does it take to become euthyroid?
What does that mean? Should surgery be delayed?
Definition
6-8 weeks. Heart rate is <80 with an absence of tremors. Delay surgery if these requirements are not met, unless emergency.
Term
What are the anesthetic complications with hyperthyroidism?
Definition
*cont. anti-thyroid meds through morning of surgery

*delay surgery if not euthyroid

*if not euthyroid, prevent sympathetic responses (deep)

*avoid meds that increase SNS (ketamine)

*use direct acting vasopressors for hypotension

*difficult airway if goiter present

*myasthenia gravis incidence higher in hyperthyroidism
Term
What is a complication of a thyroidectomy?
How do you evaluate pre and post-op?
Definition
*Recurrent laryngeal nerve damage.
-unilateral damage: hoarseness
-bilateral damage: intubation

*Have pt say "EEEE", laryngoscopy, and document hoarse voice pre & post-op!
Term
What is a tx for Hypoparathyroidism?
Definition
Calcium gluconate 10-20cc of a 10% soln.
Term
Name two signs to test for hypoparathyroidism.
Definition
Chvostek's sign: facial spasm when face tapped.
Trouseau's sign: spasm of hand or foot w/ BP cuff pressure.
Term
What are some causes of hypothyroidism? Can you have a goiter w/ hypothyroidism?
Definition
*radioactive iodine, neck irradation, surgical removal.

*fo shizz!
Term
What are s/s of hypothyroidism?
Definition
lethargy, cold intolerance, slow movements, bradycardia, decreased myocardial contractility, increased pericardial fluid, decreased response to hypoxia.
Term
Is it safe to proceed w/surgery with mild to moderate hypothyroidism?
Definition
You know it is.
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