Term
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Definition
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Term
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Definition
1. protic (H bond donor)
2. Aprotic (no h bond donor) |
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Term
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Definition
1. donor (good lewis base)
2. nondonor (no lewis base prop) |
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Term
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Definition
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Term
|
Definition
H20
CH3OH
EtOH (alcohols)
HCONH2
excellent anion and cation stab |
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Term
|
Definition
DMF
DMSO
HMPA
CH3CN
excellent cation stab
very reactive nuc |
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Term
|
Definition
acetic acid
good cation and anion stab |
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Term
| nonpolar, aprotic, donor solvents |
|
Definition
ether
THF
1,4 dioxane
good cation stab |
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Term
| nonpolar, aprotic, nondonor solvents |
|
Definition
alkane
CH2Cl2
CHCl2
Benzene
no cation or anion stabilization |
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Term
| solvation does what to bronsted acidity |
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Definition
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Term
| strongest acid that can exist in any solvent is... |
|
Definition
| conjugate acid of that solvent itself |
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Term
|
Definition
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|
Term
| same column nuc/basicitiy |
|
Definition
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Term
|
Definition
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|
Term
| in E2, what wins, Zaitsev or anti? |
|
Definition
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Term
|
Definition
1. strong nuc (and weak base)
2. Solvent choice |
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Term
|
Definition
1. a, b C branching
2. bulky, branched nuc |
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Term
| Sn1, E1 what prime alkyl halide |
|
Definition
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|
Term
|
Definition
polar, protic, donor solvents
alcohols, formic acid, mixture of H20 with alkyl halide soluble |
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|
Term
| Sn1 stereochemically selective? |
|
Definition
| No, unlike Sn2, form sp2 carbocation achiral planar intermediate, which leads to a racemic mixture |
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Term
| 2 prime alkyl halides, what reactions possible |
|
Definition
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|
Term
| Favor Sn2, E2 during 2 prime alkyl halide rxns |
|
Definition
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|
Term
| favor E1, Sn1 during 2 prime alkyl halides |
|
Definition
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Term
|
Definition
ch2I2 zn-Cu in either
concerted syn addition
carbene |
|
|
Term
|
Definition
a elimination
stereochemically preserved |
|
|
Term
| directed cycloproponation |
|
Definition
| only forms on side with O:- |
|
|
Term
| ways to make alcohol better leaving group |
|
Definition
protonation (alkyl halide, acid)
TsCl or MsCl in pyridine (retention)
thionyl chloride inversion
PBr3 inversion |
|
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Term
| 1 prime alcohol to aldehyde, ketone |
|
Definition
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|
Term
| 1 prime alcohol into ketones and carboxylic acids |
|
Definition
CrO3 in H2O
aq conditions
KMnO4
K2Cr2O7 |
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Term
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Definition
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Term
|
Definition
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