Term
Is safe and efficacious in the treatment of nausea and vomiting in pregnancy |
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Definition
Doxylamine, Droperidol, Metoclopramide, Pyridoxine |
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Term
Nausea and vomiting in pregnancy |
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Definition
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Term
General physiologic and pharmacokinetic changes seen in pregnancy |
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Definition
decreased proportion of bound drug with highly protein bound medications |
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Term
Risks of using NSAIDs (including aspirin) during pregnancy |
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Definition
prolonged gestation/labor; oligohydramnios; hemorrhage; narrowing of the fetal ductus arteriosus |
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Term
The iPLEDGE program is associated with this drug |
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Definition
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Term
Metabolic activity of CYP1A2 and 2C19 |
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Definition
often decreased during pregnancy |
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Term
Have an increased volume of distribution and decreased half life in pregnant women compared to non-pregnant |
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Definition
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Term
after the embryonic period (between weeks 2 and 8 postfertilization) the conceptus is renamed this |
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Definition
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Term
pregnancy lasts approximately: |
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Definition
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Term
refers to the age of the embryo or fetus beginning with the first day of the last menstrual period which is about 2 weeks prior to fertilization |
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Definition
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Term
the number of times a woman is pregnant |
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Definition
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Term
number of pregnancies exceeding 20 weeks gestation; relates information regarding the outcome of each pregnancy |
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Definition
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Term
increases progressively; peak values on average 30% to 50% more than preconception levels by 25- to 30-weeks gestation |
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Definition
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Term
hypercoagulability: risk of venous thromboembolism |
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Definition
4 times greater in pregnancy |
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Term
expansion of both plasma and red blood cell volumes |
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Definition
leads to an expansion of total blood volume by approx. 1.5 to 1.6 L (40% increased in volume compared to non-pregnant women) |
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Term
overall decreased lung capacity by 5% |
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Definition
maternal oxygen consumption increases over gestation reflecting the increasing demands of the growing fetus and placenta |
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Term
renal blood flow increased across gestation |
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Definition
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Term
renin-angiotensin aldosterone system |
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Definition
increased activity during pregnancy |
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Term
GI motility and gastroesophageal sphincter tone |
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Definition
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Term
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Definition
Absorption, distribution, metabolism, excretion |
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Term
do not survive due to the complexity of fertilization and subsequent pregnancy effects |
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Definition
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Term
survive the first 2 weeks of gestation are lost spontaneously later |
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Definition
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Term
baseline prevalence of major congenital malformations |
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Definition
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Term
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Definition
account for 20% of infant deaths |
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Term
birth defect risk is greatest |
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Definition
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Term
the ability of an agent to cause a defect or malformation in a fetus |
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Definition
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Term
Francis Kelsey refused to approve this in US despite culture and laws telling her to approve it |
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Definition
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Term
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Definition
Accutane (avoid in pregnancy) |
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Term
most modifiable cause of birth defects, no safe level of exposure, increased incidence of SIDS, Colic, Respiratory problems, Hospital admissions |
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Definition
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Term
causes catecholamine release and vasoconstriction |
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Definition
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Term
increases risk of CVD, toxins in tobacco smoke are responsible for majority of adverse health effects |
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Definition
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Term
recommend iron in pregnancy |
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Definition
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Term
Folic acid dosing in pregnancy |
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Definition
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Term
characterized by severe persistent vomiting; 3rd leading cause of hospitalization in pregnancy |
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Definition
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Term
one of the most effective treatment options for N/V in the past |
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Definition
Bendectin (tri-ingredient product) |
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Term
1st line for heartburn in pregnancy |
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Definition
calcium carbonate, magnesium hydroxide, aluminum hydroxide, sodium bicarbonate (best to avoid) |
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Term
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Definition
Ranitidine, cimetidine (both cross placenta but are considered safe) |
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Term
treatment for constipation in pregnancy |
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Definition
bulk forming agents (bran, psyllium, methylcellulose) |
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Term
The higher the maternal plasma level |
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Definition
the higher the transfer to milk |
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Term
more medication can enter milk in colostral phase; limited volume of colostrum |
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Definition
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Term
less medication enter; larger volume |
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Definition
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