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PnA-Coke
pain n anixety
50
Science
Graduate
03/04/2011

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Cards

Term
minimal sedation
Definition
oral sedation with ONE agent not exceeding MRD and no loss of protective reflexes
Term
Moderate Sedation
Definition
includes oral sedation and/or intravenous sedation. minimal effect on protective reflexes, andairway not effected
Term
Deep sedation
Definition
partial loss of protected reflexes and airway can be affected
Term
General Anesthetia
Definition
loss of all protective reflexes and airway is affected (intubation)
Term
benzodiazpenes
Definition

inhibit GABA reuptake

wide margin of safety

safe for heart

rapidly absorbed

half lives 1.5-70

Term
xanax (alprazolam)
Definition

no active metabolites and rapid uptake

half life 8-12 hours

veru low side effects, good antianixety

dental dose-1-.5 hs 1 hr prior

Term
halcion (tirazolam)
Definition

short half life 2-3 hr 

anterograde amnesia

denal dose .25-.5 1 hr piror

Term
ADA MRD sedation guidelines
Definition
you can give MRD and ONE supplemental dose not to exceed one half life of the inital dose given THE DENTIST HAS DET THE CLINICAL HALF LIFE HAS EXPIREd of initiatl dose must know half lives
Term
Versed (midazolam)
Definition

only given IV and oral liquid half life 2-4 hrs

profound amneisa

Term
procaine
Definition

greatest vasodilation

ester 

potency and tox 1

9.1

.1hr

no pulpal

Term
Lidocaine
Definition

amide

potency tox 2

7.9

1.6 hrs

2.3 min

Term
mepivacaine
Definition

amide 

potency 2

7.6

LEAST VASODILATION

Term
bupivacaine
Definition
stronger protein binding
Term
normal healthy patient
Definition
.2% epineprhine
Term
midazloam
Definition

1-2 hrs

should NOT be used with other narcotics

oral 15-20 mg

Term
what can be given to reverse benzodiazpenes?
Definition
Flumazenil
Term
Z drugs
Definition

Zolpidem-ambien

zaleplon-sonata

rapid onset of effect and short duration of action 30=60 min and 4 hrs

non benzo or barb

Term
ambien (zolpidem tartrate)
Definition

gaba, empty stomac, half life 2-2.6 hours

dental dose-5-10 mg .5 hr pripr

Term
zolpidem (ambien)
Definition

5-15 mg

1.5 hr half life

excellent placesment 

reversible, no active metabolites

add No prn

Term
antihistamines
Definition
promethazine-phenergan (dd  20-50 mg 1 hr prior)
Term
diffusion hypoxia (Fink principle)
Definition
when recovering from N20, large amounts get dissolved in body tissue and p02 decreases leading to hypoxia, prevent this by increasing fractional inspired O2 when recovering
Term
hydroxyzine (atarax)
Definition

protocol

half life 3-7 hrs

dose-10-50mg

no amnesia, non reversible

Term
guedel's staging of anesethia STAGE 1
Definition

analgesia/sedation

MUST keep orally sedated patients in this stage

NO airway compromise, altered perception to pain can repsond to verbal

Term
stage 2
Definition

delirum/excitement

once get to stage 2 slippery slope

Term
stage 3
Definition

surgical anestheia

lose potective reflexes and or ability to maintain an airway

Term
stage 4
Definition
NNOT GOODmedullary paralysis/death
Term
pulse oximetry
Definition

GOLD standard for measure

non invasive clip that goes over finger

measures oxy blood in circulation

light monitor red

should NOT be the only thing used

Term
barbituates
Definition

opoid

non reversible

resp depressants

doesnt diminsh pain

should only be used if benzos inefective

Term
chloral hydrate
Definition

aquachloral or nortec

trichloroethanol -CNS depressant

500-1000 mg

poor choice

Term
low safety margin
Definition

chloral hydrate (LD50/ED50) parition c

BADoefficient 2-4  want a larger one 

Term
gases used the most
Definition
Desflurane and sevoflurane because lower blood gas coeffcient--easier doesnt have to staurate blood first before it can get to tissue, .42 and 
Term
halothane
Definition

was the gold standard.

blood gas coeff 2.54 (High) so slow induction

60-80 elim thru lungs

metabolite trifluroacetic acid

MAC .77

side effects-decreased BP and Hr doesnt affect systemic circulation

 

Term
dantrilene and diuretic
Definition
to reverse maligant hyperthermia (genetic)
Term
nitrous oxide on Cardiac output and ventilation
Definition

*little affect on myocardial contractility because its offset by sympathetic neurons

*produces a dose-related increase in respiratory rate that offsets a mild scresse in tidal vol

other anesethtics decrease ventilation but Nirtous helps offet

Term
Isoflurane
Definition

.2%

 

Term
halicon (triazlam)
Definition
workhorse in dentistry, benzo
Term
N20 
Definition

blood:gas coefficient .47

MAC 104%

99.5% pure and anhyrous

70% max amt 

Term
ELMA cream
Definition
lidocaine 2.5% and prilocaine 2.5%
Term
Sonata (Zaleplon)
Definition
shortest half life 1-2 hours
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