Term
| What is the dark staining band at the bottom of kinocilia? |
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Definition
| Basal bodies. This is key feature that microvilli do not have. |
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Term
| Three types of cell jxns from apical to basal |
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Definition
| Zonula occludens, Zonula Adnerense, and Macula Adherens |
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Term
| Tight jxn/ Zonula Occludens fxn? |
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Definition
| restricts even small molecules from passing through... This is a belt type jxn and is most apical. |
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Term
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Definition
| Connects to actin microfilaments in microvilli and has a looser attachement than tight and allows passage of some molecules. |
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Term
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Definition
| Use to bind cell membranes together at Zonula Adherens in the presence of calcium |
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Term
| What attaches cadherens to actin filaments and where are they found? |
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Definition
| Liker proteins, p120 catenin, B catenin, and other anchor proteins, link cadherens (Extracellular) to actin filaments (Intracellular) at the Zonula Adherens) |
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Term
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Definition
| Spot Welds, (Desmosomes) (Non classical adherens) that adhere cells to neighbor and connect to intermediate filaments and have dense plaque around them. |
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Term
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Definition
| Desmoglein and desmcollin, |
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Term
| What attaches to macular adherens (Desmosome)? |
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Definition
| Intermediate filaments find to desmoplakin which binds to plakoglobin and then plakophilin...... On the other side of the plasma membrane are the cadherin family proteins. |
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Term
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Definition
| Allow cells to be connected both electrically and metabolically and allow passage of small molecules. |
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Term
| What comprises a gap jxn? |
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Definition
| 6 subunit proteins make up a connexon and two connexons form the gap jxn. |
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Term
| What is the role of focal contacts? |
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Definition
| They connect the internal cytoskelteton (Stress fibers) with extracellular matrix (Fibronectin) |
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Term
| Difference in hemidesmosomes and desmosomes? |
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Definition
| Hemidesmosomes look like half of desmosome, but use integrine instead of cadherins to connect internal with ECM... have intermediate filaments made out of keratin attached to dystonin and plectin which is attached to integrin and then to collagen/laminin... |
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