Term
What are the 6 hormones released by the anterior pituitary? |
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Definition
1) Adrenocorticotropic hormone (ACTH) 2) Growth Hormone (GH) 3) Prolactin (PRL) 4) Thyroid-stimulating hormone (TSH) 5) Follicle-stimulating hormone (FSH) 6) Luteinizing hormone (LH) |
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Term
What are the 2 hormones that are produced in the hypothalamus and secreted in the posterior pituitary? |
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Definition
1) Vasopressin (ADH) 2) Oxytocin |
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Term
What two hypothalmic hormones effect Growth hormone? |
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Definition
1) Growth hormone-releasing hormone 2) Growth hormone release-inhibiting hormone (somatostatin) |
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Term
What hypothalmic hormone effects Prolactin? |
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Definition
prolactin release inhibitory factor (dopamine) |
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Term
What hypothalamic hormones effect FSH and LH? |
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Definition
Gonadotropin-releasing hormone |
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Term
What hypothalamic hormone affects ACTH? |
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Definition
Corticotropin-releasing hormone Vasopressin |
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Term
What hypothalamic hormone affects TSH? |
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Definition
Thyrotropin-releasing hormone |
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Term
What is the most common structure affected by pituitary masses? |
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Definition
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Term
What is the most common pituitary tumor? |
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Definition
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Term
What genetic syndromes are associated with pituitary adenomas? |
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Definition
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Term
diagnostic findings in males with hyperprolactinemia |
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Definition
1) diminished libido 2) oligospermia 3) lowered ejaculate problems 4) glactorrhea |
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Term
Diagnostic findings for hyperprolactinemia in women |
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Definition
1) menstrual changes 2) vaginal dryness |
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Term
How do you medically treat prolactinoma? |
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Definition
bromocriptine D2 dopamine receptor agonist
*can use cabergoline (dopamine agonist) |
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Term
What is the most abundant anterior pituitary hormone? |
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Definition
growth hormone, compromises 50% of anterior pituitary cells |
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Term
Where is the receptor for GH most commonly found? |
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Definition
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Term
What does GH do to persons of all ages? |
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Definition
antagonizes insulin action and impairs glucose tolerance |
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Term
increased mortality from adult GH deficiency is from what? |
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Definition
cardiovascular risk factors increased |
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Term
bone overgrowth is seen in what? |
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Definition
acromegaly - GH-secreting pituitary adenoma |
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Term
gigantism is a result of? |
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Definition
GH hypersecretion before epiphyseal long-bone closure |
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Term
How is the diagnosis of acromegaly confirmed? |
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Definition
failure to supress HG levels below 1 ul/L within 1-2 hours after an oral glucose load |
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