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drugs metabolized by CYP2D6 |
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TCA, anti-arrhythmics, BB, neuroleptics, opiods |
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cyp450 of anti-arrythmics |
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drugs metabolized by CYP2C9 |
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Definition
tolbutamide, phenytoin, warf, NSAIDs |
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Term
cyp450 with the greatest number of drugs |
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mutation in what gene can cause prolonged QT in pts taking quinidine? |
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what is the Philly chromosome? |
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Definition
extra short 22 after Bcr-Abl transloc |
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what does 9 look like after the Bcr-Abl transloc? |
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what does the bcr-abl translation product do? |
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Definition
constituitive Tyr-kinase activity |
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what drug inhibits the Bcr-Abl Tyr-kinase? |
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Her2-neu mutations associated with? |
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solid tumors i.e. colorectal |
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