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Physiology
Test 4
25
Physiology
Undergraduate 3
11/15/2010

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Term
Heart Valves close due to:
Definition
Pressure changes
Term
Heart sounds produced by:
Definition
1st sound- mitral valve closing
2nd sound- aortic valve closing
Term
Contraction phases
Definition
1) Filling
2) Isovolumetric Contraction
3) Ejection
4) Isovolumetric Relaxation
Term
Cardiac Output
Definition
-Vol of blood pumped in one minute
-CO=SVxHR (SV=EDV-ESV)
Term
Cardiac Output altered by:
Definition
-Changes to HR and SV
-Venous return is the main way to change SV, by changing EDV.
-Blood Vol determines venous return.
-In the end, increase blood vol, increase venous return, increase EDV, incrase CO
Term
Frank-Starling Law of the heart
Definition
-Heart will pump all of its preload.
-Only changes in Intracellular Ca will change contractility)
Term
Fick Principle
Definition
CO=(O2 consumption, VO2)/(O2V-O2A)
Term
Most of the blood in circulation is in:
Definition
the veins
Term
Pulse Pressure and Mean arterial Pressure
Definition
Pulse Pressure= Sys-Dias
MAP=Dias+(.33*pulse pressure)
Term
Flow
Definition
Q=change in P/R or change in P=Q*R
R is proportional to 1/(r^4)
Term
Adding resistance
Definition
In series: RT=R1+R2...
In parallel: 1/RT=1/R1+1/R2...
Term
TPR
Definition
CO=change in P/TPR
TPR=total peripheral resistance
Term
Blood Flow regulated by:
Definition
-Changes in vascular resistance
-CO2, adenosine, lactic acid, H+ all dilate the vessels
-NO also dilates
Term
Capillary hydrostatic pressure
Definition
Pc- higher on artery side of capillary. Favors movement of water from blood to interstitium
Term
Plasma oncotic pressure
Definition
-Osm pressure exerted by proteins in plasma. Favors movement from inerstitium to blood
Term
Interstitial hydrostatic pressure
Definition
Pi- usually 0
Term
Interstitial oncotic pressure
Definition
Pie-i: favors movement of fluid from interstitium to blood
Term
Net filtration
Net absorption
Definition
Net filtration is about 10mmHg
Net absorption is about -8mmHg
Term
Edema Caused by:
Definition
heart failure, dec in plasma proteins, capillary permeability, lymph system blocked
Term
Baroreceptors
Definition
-Stretch receptors in aortic arch and carotid sinus. Inhibit sympathetic
-If BP drops, HR inc and vessels constrict
-If BP increases- HR drops and vessels dilate.
Term
Not all tidal volume enters alveoli?
Definition
Yes, because of the dead space taken up by the conducting zone, about 150mL
Term
Normal PaCO2, PaO2, and R
Definition
PaCO2=40mmHg
PaO2=100
R=VCO2/V02=.8
Term
Law of Laplace
Definition
-Harder to keep small alveoli open, easier to keep large alveoli open.
-This effect is reduced by surfactant
Term
Intrapleural Space at rest
Definition
-5cm H20
Term
Gas exchange
Definition
-PO2 in air is .21, CO2 is 0
-PO2 in alveolar blood is 40, CO2 is 47
-PO2 equilibrates at 100
-PCO2 equilibrates at 40
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