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Physiology Unit 1 Exam
N/A
164
Physiology
Undergraduate 2
01/11/2012

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Cards

Term
How many types of cells are there?
Definition
over 200
Term
What are the 3 types of fibers and their purpose?
Definition
Collagen (strength), Reticular (support), Elastic (recoil)
Term
Where can you find nervous tissue?
Definition
nerves, spinal cord, and the brain
Term
What is another name for neurolglia?
Definition
glial cells
Term
What are the four functions of muscle tissue?
Definition
Extensibility, elasticity, contractibility, and excitability
Term
What is the purpose of epithelial tissue?
Definition
covers/lines structures
Term
What is lumen?
Definition
The interior cavity of a hollow organ or vessel
Term
True or false:
endocrine glands act locally
Definition
False
Term
What is the overall function of CT?
Definition
Support
Term
What is TBW composed of?
Definition
ICF and ECF
Term
What conditions in the internal environment are maintained by homeostasis?
Definition
Composition of ECF, Temperature ECF, Volume of ECF
Term
All organ systems except which one function to maintain homeostasis?
Definition
Reproductive
Term
What are the two ways of maintaining homeostasis?
Definition
Negative and Positive feedback
Term
What are the four types of biomolecules?
Definition
Carbs, lipids, proteins, and nucleotides
Term
Biomolecules contain ____ atoms
Definition
carbon
Term
What is the chemical property of the hydroxyl group?
Definition
polar
Term
What is the chemical property of the sulfylhydryl group?
Definition
polar
Term
What is the chemical property of phosphate group?
Definition
polar
Term
What is the chemical property of the carboxyl group?
Definition
Acid
Term
What is the chemical property of the amino group?
Definition
base
Term
What are the three classifications of carbs?
Definition
monosaccharides, disaccharides, and polysaccharides
Term
Are carbs polar or non-polar?
Definition
polar
Term
What are two forms of carbs?
Definition
sugars and starches
Term
Glucose= _____
Definition
blood sugar
Term
Polymer subunits= __________
Definition
monosaccharides
Term
What is another name for lipids?
Definition
fats
Term
Are lipids polar or non-polar?
Definition
non-polar
Term
Define amphipathic
Definition
Having polar and non-polar properties
Term
What are the three types of lipids?
Definition
Triglycerides, Phospholipids, and steroids
Term
What is glycogen?
Definition
stored glucose
Term
What is a polymer?
Definition
A chain of subunits
Term
What is the composition of a triglyceride?
Definition
glycerol molecule and 3 FA molecules
Term
Phospholipids have a ____ head and and ____ tail
Definition
hydrophilic; hydrophobic
Term
Polar heads of phopholipids face the ____ and _____
Definition
ECF; ICF
Term
What is the purpose of the Micelle?
Definition
to transport lipid-soluble substances
Term
What is the most prevalent steroid?
Definition
cholesterol
Term
How many Amino Acids are there?
Definition
20
Term
___ are polymers of amino acids
Definition
Proteins
Term
Which protein structure has alpha helixes and beta pleats?
Definition
Secondary structure
Term
What are the two types of protein conformation?
Definition
Fibrous and Globular
Term
Describe fibrous proteins
Definition
Elongated; function in structure or contraction
Term
Describe Globular proteins
Definition
Coiled, folded, and irregular
Term
What are four functions (forms) of globular proteins?
Definition
Enzymes, hormones, carriers, and receptors
Term
What are the functions of nucleotides and nucleic acids?
Definition
transfer of energy and formation of genetic material
Term
What are the four nucleotides used for energy transfer?
Definition
ATP, ADP, NAD, and FAD
Term
Some nucleotides form ____ structures
Definition
ring
Term
Where do you find the most mitochondria?
Definition
In skeletal/cardiac muscle and nerves
Term
Nucleotides can also be used for ___ _____
Definition
intracellular signaling
Term
What are the two polymers of nucleotides?
Definition
DNA and RNA
Term
What are the three basic components of all cells?
Definition
Plasma membrane, nucleus, and cytoplasm
Term
What is a function of transmembrane proteins?
Definition
ion pumps
Term
What are the three components of the nucleus?
Definition
Nuclear envelope, nuclear pores, and nucleolus
Term
ID:
the double membrane of the nucleus
Definition
nuclear envelope
Term
What are the membranous organelles?
Definition
ER, Golgi, Mitochondria, Lysosomes, and peroxisomes
Term
ID:
the holes in the membrane of the nucleus
Definition
nuclear pores
Term
ID:
site of ribosomal RNA synthesis
Definition
Nucleolus
Term
What is another name for Chromatin?
Definition
DNA
Term
What are the two components of the cytoplasm?
Definition
cytosol and organelles
Term
What are the two components of the cytosol?
Definition
Inclusions and secretory vesicles
Term
Define inclusions
Definition
temporary structures in some cells ( triglycerides and glycogen)
Term
Define secretory vesicles
Definition
membrane-bound sacs
Term
What is the nickname for the ER?
Definition
Network
Term
What is the function of smooth ER?
Definition
steroid and triglyceride production
Term
What is the function of rough ER?
Definition
Protein synthesis
Term
What is an examples of a quaternary structure?
Definition
hemoglobin; 4 polypeptide chains
Term
What is the function of the golgi apparatus?
Definition
cisternae that receive, modify, and send out proteins (cis face to trans face)
More prominent in secretory cells
Term
What is another name for the mitochondria and why?
Definition
Cell "powerhouse" because it produces ATP
Term
___ ____ structure is VERY IMPORTANT in ATP production
Definition
Double Membrane
Term
What is the purpose of the cristae of the inner membrane?
Definition
to increase SA so more ATP can be produced
Term
What are two functions of lysosomes?
Definition
autophagy and endocytosis
Term
What toxin is produced by peroxisomes?
Definition
hydrogen peroxide
Term
What is an example of a non-membranous organelle?
Definition
ribosome
Term
Where are ribosomes made?
Definition
the nucleolus
Term
What are the two components of ribosomes?
Definition
Large and small subunit
Term
What are the locations for ribosomes?
Definition
cytosol, RER, Mitochondria
Term
What are the three types of filments that make the cytoskeleton?
Definition
intermediate filaments, microfilaments, and microtubules
Term
T/F:
Microvilli stick out from the plasma membrane
Definition
False; they push the membrane up and over the cell
Term
What are two examples of intermediate filaments?
Definition
myosin myofilaments and keratin
Term
What are the three types of membrane junctions and their purpose?
Definition
desmosomes (prevents cells from being pulled apart), gap junction (let inside cell A to talk to inside cell B), and tight junctions (sealant)
Term
What is one word to describe the function of desmosomes?
Definition
anchor (zipper)
Term
What is one word to describe the function of gap junctions?
Definition
tunnel (found where fluids are separated)
Term
Define metabolism and provide two types
Definition
All chemical reactions in the body; Anabolism (build-up; need E) and Catabolism (break-down; Releases E)
Term
Metabolism is highly regulated by _____
Definition
enzymes
Term
Define membrane transport
Definition
moving things in and out of cells
Term
What are the four types of membrane transport?
Definition
Diffusion (non-polar and small polar molecs), Carrier Proteins (larger polar molecs), Channels (water and ions), Vesicles (protein and macromolecules)
Term
What are the two categories of intercellular communication?
Definition
Direct (gap junctions) and indirect (chemical messengers)
Term
How does the nucleus of a cell control cellular activity?
Definition
DNA
Term
How does DNA control cellular activity?
Definition
DNA codes for cellular proteins
Term
If DNA is only in the nucleus, how can it control cellular activity outside the nucleus?
Definition
RNA
Term
Define gene
Definition
segment of DNA with a specific order of linked nucleotides that "codes" for a specific protein
Term
What part of the DNA contains the Codon?
Definition
mRNA
Term
What section of the DNA contains the triplet?
Definition
sense strand
Term
Define transcription
Definition
RNA is synthesized from the sense strand of DNA (inside nucleus)
Term
Define translation
Definition
polypeptides are synthesized using RNA codons as a template for assembly of the correct order of amino acids (outside nucleus)
Term
What are the three types of RNA?
Definition
mRNA (messenger); rRNA (ribosomal); tRNA (transfer)
Term
What is responsible for "zipping" and "unzipping" DNA?
Definition
RNA polymerase
Term
T/F:
Exons code for proteins
Definition
True
Term
T/F:
Introns code for proteins
Definition
False; they get removed
Term
What protects the mRNA from being "eaten" once it enters the cytoplasm?
Definition
RNA cap
Term
What is energy metabolism?
Definition
reactions involved in energy storage and use
Term
Identify:
the total mass of reactants equals the total mass of the products
Definition
Law of Conservation of Energy
Term
What are the three classifications of substances involved in metabolic pathways?
Definition
reactants, intermediates, and end-products
Term
What is the splitting of water?
Definition
hydrolysis
Term
Define condensation
Definition
water forming
Term
Define phosphorylation
Definition
addition of a phosphate (condensation)
Term
Define Dephosphorylation
Definition
removal of a P (hydrolysis)
Term
Define oxidation
Definition
removal of electrons
Term
Define reduction
Definition
acceptance of electrons
Term
H ___ are commonly referred to as reducing equivalents
Definition
atoms (not ions)
Term
Define energy
Definition
capacity to perform work
Term
What is the first law of thermodynamics?
Definition
energy can't be created or destroyed
Term
What is the second law of thermodynamics?
Definition
natural processes tent to proceed in the direction that spreads out the energy
Term
True/False:
equilibrium is achieved if [reactant] = [product]
Definition
False; the energy amount has to be the same
Term
An increase in ___ will push a reaction forward while an increase in ___ will move it back
Definition
[reactants]; [products]
Term
How are reaction rates expressed?
Definition
moels/liter*sec
Term
What are three factors that effect reaction rates?
Definition
[reactant] and [product]; temperature; and Activation energy barrier
Term
How do enzymes increase reaction rates?
Definition
by decreasing the activation energy
Term
Describe enzymes (4)
Definition
biological catalyst; substrate specific; do not change the nature of the reaction or the final product; enzymes themselves are not changed by the reaction
Term
What is the lock and key model?
Definition
substrate specificity model that says the shape of the substrate complements the active site of the enzyme; does not explain reverse reactions
Term
What is the induced-fit model?
Definition
substrate specificity model that states that both substrate and product can bind to the active site allowing for a reversible reaction
Term
What 5 factors impact enzyme activity?
Definition
temperature; pH; cofactors and coenzymes; concentration of enzyme and substrate; affinity
Term
What happens when a reaction exceeds the optimum temperature?
Definition
the protein becomes denatured
Term
How does acidity effect enzyme activity?
Definition
by causing structural changes and altering the charge at the active site
Term
What is the purpose of co-factors?
Definition
to help lock the substrate into its active site; helps the enzyme hold its shape
Term
Describe coenzymes (3)
Definition
vitamin-derived cofactors; can carry chemical groups from one group to another; can be reused
Term
What are the three important metabolic coenzymes?
Definition
FAD (flavin adenine dinucleotide); NAD (nicotinamide adenine dinucleiotide); and CoA
Term
What is saturation?
Definition
when all enzymes are full of substrate; gives a faster reaction rate
Term
Define affinity
Definition
the measure of how tightly substrate molecules bind to the active site of an enzyme
Term
What are the three ways of altering enzyme activity?
Definition
allosteric regulation, covalent regulation, and feedback inhibition
Term
What happens in allosteric regulation?
Definition
a modulator binds at the regulatory site and changes the shape of the active site (acts as an activator or inhibitor)
Term
What is covalent regulation?
Definition
change in the enzyme's activity occur through covalent bonding of a specific chemical group to a site on the enzyme
Term
How does feedback inhibition work?
Definition
an intermediate product in the metabolic pathway allosterically inhibits an enzyme that catalyzes an earlier reaction in the same pathway
Term
What is the first enzyme used in the krebs cycle
Definition
Citrate synthase (inhibited by ATP)
Term
What is the central reaction in energy metabolism?
Definition
glucose oxidation
Term
what are the two processes for ATP synthesis?
Definition
Substrate-level phos.("takes" from others) and oxidative phos (uses "surroundings")
Term
Substrate-level phos. is _____ while oxidative phos is _____
Definition
anaerobic; aerobic
Term
how is energy released from ATP?
Definition
ATP hydrolysis
Term
ATP hydrolysis ____ ____ formation
Definition
drives ATP
Term
What are the three stages of glucose oxidation?
Definition
Glycolysis; Kreb's cycle; Oxidative phosphorilation
Term
What are the other two names for the Kreb's cycle?
Definition
Citrid acid cycle (CAC); Tricarboxylic acid cycle (TAC cycle)
Term
how many steps are there in glycolysis?
Definition
10
Term
What are the two most important molecules involved in Glycolysis?
Definition
Pyruvate (pyruvic acid) and NAD+
Term
What is the slowest enzyme in glycolysis?
Definition
PFK
Term
Is glycolysis aerobic or anaerobic?
Definition
anaerobic
Term
Where does glycolysis take place?
Definition
cytosol
Term
Where does the Kreb's cycle take place?
Definition
mitochondrial matrix
Term
Where does oxidative phosphorilation take place?
Definition
inner mitochondrial membrane
Term
What constitutes one full run of the Kreb's cycle?
Definition
Glucose--> 2Pyruvate--> 2 Acetyl CoA--> each acetyl CoA--> one full cycle
Term
How is ATP made in the Kreb's cycle?
Definition
substrate-level phosphorylation
Term
The Kreb's cycle is _____
Definition
anaerobic
Term
How many times does the Kreb's cycle occur per glucose molecule?
Definition
twice
Term
What are the two processes involved in oxidative phosphorylation?
Definition
ETC and Chemiosmotic coupling
Term
What serve as the energy source for making ATP in oxidative phosphorylation?
Definition
reduced coenzymes
Term
What are the two substances that release electrons to the ETC?
Definition
NADH + H+ and FADH2
Term
What is the final electron receptor in the ETC?
Definition
O2
Term
What is the other important substance in the ETC and why?
Definition
Cytochrome; H+ pumps
Term
Where do electrons come from in the ETC?
Definition
H+ atoms
Term
in chemiosmotic coupling, how many hydrogens does it take to make 1 ATP?
Definition
4
Term
NADH (___ H+) = ___ ATP
Definition
10; 2.5
Term
FADH2 (___ H+) = ___ ATP
Definition
6; 1.5
Term
How many ATP are made from GLycolysis the linking step and the Kreb's cycle?
Definition
32
Term
What is BMR?
Definition
basal metabolic rate; the metabolism of cells at rest
Term
how many O2 are used for every glucose that undergoes oxidative phos.?
Definition
6
Term
What is the law of mass action?
Definition
an increase in reactant concentration relative to product concentration tends to push a reaction forward; the opposite will push it in reverse
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