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Physiology Quiz 02
Physiology Quiz 02
79
Pharmacology
Graduate
01/25/2012

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Cards

Term
Types of Pain and 3 types of Characteristics
Definition
-Fast: .1 sec; sharp; not in deep tissues
-Slow: 1sec or more; chronic, throbbing, burning, aching; skin and deep in tissues
Term
3 Types of Stimuli to excite Pain Receptors, aka Free Nerve Endings
Definition
Mechnical, Thermal, and Chemical
Term
What stimuli does fast pain use? Slow?
Definition
-Mechanical and Thermal
-Mechanical Thermal and Chemical
Term
Example of Chemicals
Definition
Bash Pap
-BradyKinn, Acids, Serotonin, Histamine
-Potassium, AcH, Proteolytic Enzymes
Term
Pain is Correlated with...
Definition
RATE of tissue damage, not TOTAL.
Explains Bell Shape Curve
Term
Dual Pathways, composed of?
Definition
Fast and Slow pathways for brain
Fast: small A* fibers to peripherial nerves at 6-30m/sec
Slow: C fibers to spinal cord at .3-2m/sec
Term
Where does Fast pathway go once in thalamus? Slow?
Definition
Fast: Somatosensory Areas using gultamate and neospinothalmic
Slow: Stays centralized near pons, medulla, midbrain, etc. using Paleospinothamic and Substance P.
Term
What is Analgesia?
Definition
Suppress input of pain signals to NS. Explains why each person vaires in pain reaction
Term
Components of Analgesisa system and how it works.
Definition

Also know as Opiate System. Enkephalins and Endorphins are Morphine like substances suppress pain in TWO areas: 1-Spinal Cord 2-Raphe Nucleus

 

*Similiar to Anterolateral System because it crosses over early in spinal cord

Term
Most Important Opiates and Locations
Definition
Again, are Enkephalins and Endorphins (Morphine-like) composed of...BadMotherDentalLover
1)B-endorphin - Hypothalmus
2)Met-enkephalin - Brainstem/spinal cord
3)Dynorphin - Dorsal Horns
4) Leuenkephalin - Brainstem/spinal cord
Term
How is Inhibition of Pain by Simultaneous Tacticle Sensory achieved?
Definition
When Stimulate peripheriial tacticle receptors such as Large AB, it does LATERAL INHIBITION in spinal cord.
*Explains why Rubbing near pain, relieves it.
Term
Referred Pain = ?
Definition
Feel pain in remote area from cause -> viseral nerves
Term
What is a Headache and what Two Main Types?
Definition
Pain on surface and deep in structures of Cranial.
1) From inside [Intracranial]
2) From outside [Extracranial]
Term
Properties of Intracranial
Definition
Saints Mess up the TouchDown.
Sinuses of venous
Mengines
Tentorium
Dura
Term
Types of Intracranial Headaches
Definition
Fudge My Crappy MAP
1)Flotation is removed = stretches dura
2) Menigitis = inflammed meninges, dura, and v. sinuses
3) Constipation
4) Migraine
5) Alcohol
6) Pressure of Cerebralspinal Fluid down by 20ml
Term
How does Constipation affect? Migrane?
Definition
1) Sensory Tracts in Spinal Cord are cut or toxic products changes circulatory system of body
2) vascular abnormality and prolonged artery tension
Term
How Does Migranes effect Headaches
Definition
Vascular abnormal and/or prolong artery tension
Term
3 Types of Extracranial Origins
Definition
1) Muscle Spasm
2) Nasal Sys irritated/infected
3) Eye Disorders
Term
3 Types Eye disorders
Definition
Focusing is hard/difficult
Reflex Spasm
Excessive light rays, i.e. UV
Term
Thermal Sensations
Definition
1) Cold
2) Heat
3) Cold-Pain and Heat-Pain
Term
Pathway of Receptors and Neural Fxn of Retina
Definition
Light rays -> lens sys -> vitreous humor ->retina -> excitation of rods/cones -> signals transmitted through nerons -> optic nerve/cerebral cortex
Term
*note, light must move through quite a bit of "muck" to get to the rods and cones. What are the "MUCK"
Definition
bipolar cells , amararine, and horizontal cells
Term
What is the purpose of the melanin in the pigmented layer.
Definition
Its black to absorb light so that eye doesn't reflect. Also there's a lot of Vit-A in pigmented layer too.
Term
Rods and Cones have same fxn but...
Definition
different spectral sensitivity.
Term
Major Functional Segments of the Eye
Definition
1) Outer segment
2) Inner segment
3) Synaptic body
Term
Eye: Out Segment = ?
Definition
-Conjugated proteins of Rhodopsin(rods) and Color Pigments(cones).
-transmembrane protein
-40%of entire mass
Term
Eye: Inner Segment = ?
Definition
-The Usuaul cytoplasmic organelles (i.e. mitochondria)
Term
Eye: Synaptic Body
Definition
Connects with subsequent neuronal cells
Term
Vit A does what?
Definition
Precursor for Rods and Cones synthesis.
Term
Photo-chemistry of Vision
Definition
-Decomposition of rods and cones when exposed to light.
-excite nerve fibers
-Light sensitive chemcicals (Rhodopsin and Cones).
Term
Is it hyper or depolarization when excite rods
Definition
Hyperpolariziation.
Which means its going to be more negative inside.
Term
How Does Rhodopsin Cause Hyperpolarization
Definition
Decreases rod membrane conductance for sodium ions -> so when light, cGMP blocks sodium channels, when dark, cGMP opens channels.
Term
Phototransduction in the Outer Segment
Definition
Light hits Rhodopsin -> G-Protein Transducin -> cGMP Phosphodiesterase which splits cGMP ->5'GMP and closes Na gated sodium channels.
Term
Photopsins and Scotopsins
Definition
cones, rods.
Term
Colorsensitive pigments of cones = ?
photochemicals in cones =?
Definition
-combination of retinal and photopsin
-chemical composition of rhodopsin in rods
Term
Neural Function of Retina: Rods and Cones
Definition
transmit to OUTER PLEXIFORM layer to synapse with BIPOLAR and HORIZONTAL cells
Term
Neural Function of Retina: Horizontal cells
Definition
-outer plexiform to bipolar cells
Term
Neural Function of Retina: Bipolar cells
Definition
-rods and cones and horizontal cells to ganglion cells and amacrine [plexiform layer]
Term
Neural Function of Retina: Amacrine
Definition
-2 directions:
1)bipolar to ganglion
2)within plexiform layer (bipolar to ganglion or amacrine)
Term
Neural Function of Retina: Ganglion
Definition
Retina to optic nerve
Term
What are inhibitory, excitatory neurotransmitters of Retinal Neurons
Definition
Inhibitory: GABA Glycine, Dopaminee, AcH
Excite: Glutamate
*note: AcH can be both....but in the diagram, was inhibit
Term
There are two Types of Transmission of Signals in Retinal Neurons
Definition
1) Action potential uses Ganglion
2) Electrotonic Conduction uses electricity..
Term
What are Electronic Conduction
Definition
Electrical currents from dendrites. Its importance because it allows us CONTROL, while Action Potentials, once it starts, it doesn't stop!
Term
Visual Pathway
Definition
Optic Nerve -> cross at optic chiasm ->optic tracts -> dorsal lateral geniculate (thalamus) -> GenicuLocalCarine fibers -> visual cortex -> calcarine fissure
Term
Fixation Movements of Eyes
Definition
1) Voluntary: Premotor cortical of Frontal Lobes
2) Involuntary: secondary visual of occipital cortex
Term
Visual Pathway to Other Body Areas
Definition
Circadian rhythms (phsyiolcogical changes of night and day)
Term
Primary Visual Cortex
Definition
All information comes here first into Macula (where fovea lies).
Term
Secondary Visual
Definition
aka Visual Association Areas
-crosses calcarine fissure and is where we get detailed information distributed out (i.e. forms, motions of objects)
Term
Analysis of Visual Info is separated into two areas after the primary cortex
Definition
1)3d position, gross form, and motion
(where each object is and is it moving)
2) visual Detail and Color
(what object is and what it means)
Term
Eve Movements and control
Definition
1)Reciprocal Cranial (A pair, 1 muscle relax, the other contracts).
2)Medial and Lateral Recti:
-side to side
3)Superior/Inferior Recti = Upward/downward
4)Inferior/Superior Oblique = rotate eyeballs
4)Inferior
Term
Impedence Matching
Definition
1)since STAPES is (3/4) amplitude from prior, the OSSICULAR LEVER increases the force of by 1.3, despite the distance/movement being decreased.
2) STAPES is also much smaller than Tympanic Membrane.
Term
Why need all this force in IMPEDENCE MATCHING
Definition
Fluid is hard to move through compared to air when talking about tympanic membrane
Term
Loudness =?
Definition
1) Outer hairs feel more intensity
2) Basiliar memb and hairs virbate at more rapid rates
3) Spatial summation due to increase amplitude of vibration
Term
Main Fxn of Chochlea? Organ of Corti?
Definition
Choclea conducts vibrations and houses the Organ of Corti which generates nerve impusles when basiliar fiber vibrates.
Term
VMT RB =?
Definition
The anatomy of the Cochlea:
Sacula Vestibuli
--->super thin Reissner's Memb
S. Media
--->Basiliar Membrane
S. Tympani
Term
Basiliar Membrane contains
Definition
Organ of Corti, which has sterocillia.
Term
Transmission of Sound is comparable to?
Definition
Initially: basilar memb bends (its elastic!) in direction of round window.
So its comparable to arterial walls or rock on a pond.
Term
Frequency/Pitch differences
Definition
1) High is closer
2) Medium is further and not as much of a dip
3) Low is pratically no dip and really far before goes up
Term
Tectorial membrane?
Definition
It separates the outer and inner hairs of the organ of corti.
Part of a STIFF/RIGID structure with Reticular Lamina and the sterocillia attached to it.
Term
Difference between the hairs in the Organ of Corti and their functions!?
Definition
Outer (more numerous) but Inner(is where 90-95% of nerve impulses stop).
The Outer then must be for Sensitivity and Tuning as we still get deaf if we lose outer hairs
Term
How is deploarization in the Organ of Corti
Definition
It has influx of K not Na.
When the basiiliar fibers vibrate, so does the rigid structure composed of the tectorial membrane, Reticular Lamina and Sterocilia Hairs (outer and Inner).
Term
Tonotopic Maps Show?
Definition
Specific sounds go to specific areas of brain.
1) High freq = posterior, Low freq = anterior
2) Primary gets directly from MGB (medial geniculate body) and Association gets from Primary and Thalamaic
Term
How do we measure sound?
Definition
By decibal, a log of intensities.
Term
Refractive Index
Definition
velocity through air/velocity through substance
Term
refraction
Definition
bending of light ray
Term
what influences degree of refraction?
Definition
1) Angle
2) Substance
Term
Convex? Concave?
Definition
Focus. Diverge
Term
Focal Length
Definition
when the width increases, the curvature increases, brings rays closer to center of lens.
Term
How measure Refractive Power?
Definition
Diopters = 1m/Focal Length
Term
How is the Eye Like A Camera?
Definition
Retina = photo detector
cornea/lens = focus
Optic Nerve = cable
Brain = CPU
Term
4 Refractive Interfaces
Definition
1) Air with anterior
2) Anterior with Aqueous humor
3) Aqeuous humor with Posterior
4) Posterior with Vitreous
Term
What is Accomdation. How is it different in different patients?
Definition
Degree of elasticity of the lens...
Children have 14, Adults less. Old have NONE = Presbyopia
Term
Presbyopia?
Definition
No accomdation (usually with Older People age 70
Term
Pupillary Diamter Determined by?
Definition
Iris = regulat amount of light
Dark = increase 8mm, Light = decrease 1.5mm
Term
Depth of Focus of lens
Definition
When increase pupillary diamter, depth of focus downn, because blurry, because goes away from optimal focal point
Term
Errors of Refraction
Definition
Enough Hunting Men Kyle
1) Ennetropia = normal
2) Hyperopia = farsight = fixed by convex
3) Myopia = near = fixed by concave
Term
Astigmatism
Definition
Too great curvature = focus at different distance from plane at right angles....1 plane has more refractive power than the other
Term
How know Depth Perception
Definition
1) Prior Knowledge of Size of Image
2) Moving Parrallax = image further = slower
3) Steropsiss: binocular vision = 2 images
Term
Tonometry
Definition
Intraocular Pressure = 12-20mmHg
If more than 40 = glaucoma.
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