Term
Term: Function of body parts; how life works |
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Definition
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Term
Term: How things work together |
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Definition
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Term
Term: Physiology gone wrong; disease |
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Definition
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Term
Term: Structural units of life |
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Definition
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Term
Term: Stem cells specialize into specialized cells |
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Definition
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Term
What are the three tissue types? |
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Definition
Muscular Nervous Epithelial |
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Term
What are muscular tissues made of? |
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Definition
Actin and myosin proteins |
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Term
What are the three types of muscular tissue? |
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Definition
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Term
What is the function of skeletal muscle tissue? |
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Definition
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Term
What is the function of cardiac muscle tissue? |
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Definition
Pumps blood; heart movements |
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Term
What is the function of smooth muscle tissue? |
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Definition
Responsible for involuntary muscle movement (artery tubes, gut, moves blood and chyme) |
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Term
What is the function of nervous tissue? |
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Definition
Conducts electrical impulses and is in control of skeletal muscles |
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Term
How fast is nervous tissue communication? |
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Definition
Very fast (within a millisecond) |
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Term
What is the function of epithelial cells? |
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Definition
Absorption and secretion of ions and molecules |
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Term
Where can epithelial tissues be found? |
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Definition
Lining digestive, respiratory and urogenital tracts; skin |
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Term
How is epithelial tissue classified? |
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Definition
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Term
Term: Epithelium one cell layer thick |
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Definition
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Term
Term: Epithelium more than one cell layer thick |
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Definition
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Term
Term: Epithelium with cilia |
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Definition
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Term
Give an example of a place in the body where ciliated epithelium can be found |
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Definition
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Term
What is the internal environment of the body like? |
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Definition
Aqueous with extra-cellular fluid |
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Term
Term: Relative constancy of internal environment |
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Definition
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Term
What is the regular pH of the human body? |
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Definition
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Term
Term: Regulates constant glucose except after meals; role of liver |
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Definition
Homeostatic Control System |
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Term
What is the total amount of body water in the human body? |
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Definition
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Term
What two fluids in the body make up extracellular fluid, and how many liters are there of each? |
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Definition
Interstitial fluid, 11L Blood plasma, 3L |
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Term
Term: Fluid that makes up 2/3 of total body water |
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Definition
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Term
How much intracellular fluid is in the body? |
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Definition
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Term
Give an example of a natural buffer of the human body |
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Definition
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Term
Give a few examples of what homeostasis controls |
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Definition
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Term
What are the different types of chemical messengers? |
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Definition
Hormones Neurotransmitters Autocrine glands Paracrine glands |
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Term
Term: Cycle of body patterns that happen once every 24 hours, including becoming sleepy and waking up |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
0 degrees Celsius in Fahrenheit |
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Definition
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Term
5 degrees Celsius in Fahrenheit |
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Definition
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Term
10 degrees Celsius in Fahrenheit |
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Definition
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Term
15 degrees Celsius in Fahrenheit |
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Definition
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Term
20 degrees Celsius in Fahrenheit |
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Definition
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Term
25 degrees Celsius in Fahrenheit |
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Definition
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Term
30 degrees Celsius in Fahrenheit |
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Definition
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Term
35 degrees Celsius in Fahrenheit |
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Definition
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Term
40 degrees Celsius in Fahrenheit |
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Definition
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Term
How many natural elements are there? |
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Definition
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Term
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Definition
Molecules and macromolecules |
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Term
99% of all living things are made up of which elements? |
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Definition
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Term
Term: Capacity to do work |
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Definition
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Term
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Definition
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Term
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Definition
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Term
What are the three subatomic particles? |
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Definition
Proton (P) Neutron (n) Electron (e-) |
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Term
What is the atomic weight of a: Proton? Neutron? Electron? |
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Definition
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Term
Term: Number of protons in nucleus |
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Definition
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Term
True/False: In an uncharged atom, the number of P = e- |
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Definition
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Term
Term: Atoms with different numbers of neutrons |
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Definition
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Term
What are the two types of ions? |
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Definition
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Term
Term: Charged atom or molecule |
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Definition
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Term
What are the functional groups we should have memorized? |
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Definition
OH- (Hydroxyl) CH3 (Methyl) COOH (Carboxyl) NH2 (Amino) PO4 (Phosphate) |
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Term
What does hydroxyl look like? |
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Definition
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Term
What does methyl look like? |
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Definition
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Term
What does carboxyl look like? |
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Definition
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Term
What does amino look like? |
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Definition
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Term
What does phosphate look like? |
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Definition
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Term
What are the types of chemical bonds? |
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Definition
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Term
What are the two types of covalent bonds? |
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Definition
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Term
Term: Atom/molecule in which electrons are shared unequally |
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Definition
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Term
Term: Atom/molecule in which electrons are shared equally |
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Definition
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Term
Term: Dissolves in water; water-loving, polar |
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Definition
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Term
Term: Doesn't dissolve in water; water-fearing |
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Definition
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Term
Term: Scale that determines acidity and alkalinity |
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Definition
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Term
True/False: If H+>OH- then the substance is a H+ donor |
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Definition
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Term
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Definition
False, it's an H+ acceptor |
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Term
Term: Minimizes change of pH, adds H+ or OH- |
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Definition
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Term
Term: Two adjacent regions with different concentrations of particles |
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Definition
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Term
Term: Solute molecules move from high concentration to a low concentration |
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Definition
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Term
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Definition
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Term
Term: Force needed to prevent water movement |
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Definition
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Term
True/False: Carbohydrates are NOT an organic molecule |
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Definition
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Term
True/False: Carbohydrates are formed in a CH2O ratio. |
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Definition
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Term
Term: Single-ringed carbohydrate |
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Definition
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Term
Term: Double-ringed carbohydrate |
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Definition
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Term
Term: Two monosacchardes coming together to form a disaccharide and a water |
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Definition
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Term
Give an example of a common monosaccharide |
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Definition
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Term
Give an example of a common disaccharide |
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Definition
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Term
Term: Adding water to split molecules |
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Definition
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Term
Term: Many chains of monosaccharides |
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Definition
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Term
Name two very important polysaccharides in the cell membrane |
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Definition
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Term
Term: Molecules made of sugars + proteins in the cell membrane |
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Definition
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Term
Term: Molecules made of sugars + lipids in cell membrane |
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Definition
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Term
Term: Fats; soluble in nonpolar solvents |
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Definition
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Term
Are lipids hydrophobic/hydrophilic? |
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Definition
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Term
Term: 3 fatty acids + 1 glycerol |
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Definition
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Term
What is the carbon skeleton of glycerol? |
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Definition
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Term
Term: Fatty acids with only single C-C bonds |
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Definition
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Term
Term: Fatty acids with one or more C=C double bonds |
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Definition
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Term
Term: Glycerol + 2 fatty acids + phosphate + choline |
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Definition
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Term
Term: Four-ringed organic compound that performs some function to body (ex: testosterone) |
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Definition
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Term
Give an example of a VERY important steroid in the body |
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Definition
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Term
Term: Large molecules with diverse functions made of amino acids |
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Definition
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Term
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Definition
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Term
How do amino acids differ? |
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Definition
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Term
Term: Bonds that link amino acids |
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Definition
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Term
Which two groups do peptide bonds connect to link amino acids? |
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Definition
Carboxyl group to the amino group |
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Term
Show the makeup of an amino acid |
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Definition
H H O | | | N- C -C=OH | | H R |
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Term
True/False: # and sequence of amino acids are related to protein properties |
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Definition
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Term
What are the four levels of protein structure? |
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Definition
Primary Secondary Tertiary Quaternary |
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Term
Describe primary structure of proteins |
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Definition
A sequence of amino acids |
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Term
Describe secondary structure of proteins |
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Definition
Conformation; folding chain of amino acids |
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Term
Describe tertiary structure of proteins |
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Definition
Folding of alpha helix upon itself |
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Term
Describe quarternary structure of proteins |
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Definition
2 or more chains fitted together |
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Term
What are the two nucleic acids we learned about? |
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Definition
Deoxyribonucleic acid (DNA) Ribonucleic acid (RNA) |
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Term
What structures make up a nucleotide? |
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Definition
PO4 (phosphate group) + C5 sugar + Nitrogenous base |
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Term
What are the two types of nitrogenous bases? |
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Definition
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Term
What are the known purines? |
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Definition
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Term
What are the known pyrimidines? |
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Definition
Cytosine - C Thymine - T Uracil - U |
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Term
Describe the difference between purines and pyrimidines |
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Definition
Purines - double-ring Pyrimidine - single-ring |
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Term
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Definition
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|
Term
What is the function of Cyclic AMP? |
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Definition
Amplifies hormone signals |
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Term
True/False: Coenzymes such as NAD are partly made from adenines |
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Definition
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Term
List the difference between DNA and RNA |
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Definition
Deoxyribose sugar vs. Ribose sugar T vs. U 2 stranded helix vs. 1 strand Antiparallel strand vs. 1 strand DNA + histone = chromosomes; RNA not in chromosomes |
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Term
Term: Monosaccharide + monosaccharide -> Disaccharide + H2O |
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Definition
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Term
How many bonds are between A-T? |
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Definition
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Term
How many bonds are between C-G? |
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Definition
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Term
Describe the hydrogen bonds between the base pairing |
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Definition
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Term
Term: Disaccharide + H2O -> Monosaccharide + Monosaccharide |
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Definition
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Term
Show the hydrolysis of ATP |
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Definition
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Term
What are the three major parts to the Cell Theory? |
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Definition
All organisms are made of cells New cells can only be made from pre-existing cells All cells have the same fundamental chemical make-up |
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Term
What are the two broad classes of cells? |
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Definition
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Term
What is cytoplasm made up of? |
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Definition
Cytosol Organelles Plasma membrane |
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Term
What are the two processes of cell metabolism? |
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Definition
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Term
Term: Synthesis of cells - metabolism |
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Definition
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Term
Term: Breakdown of cells - metabolism |
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Definition
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Term
Term: Organelles that function as protein factories |
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Definition
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Term
Term: Segment of DNA; code for 1 polypeptide chain |
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Definition
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Term
Term: Exiting of protein out cell membrane |
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Definition
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Term
What is the process of obtaining energy? |
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Definition
Food molecules are broken down by enzymes from lysosomes, and the energy is used to form ATP |
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Term
What are the functions of the cell membrane? |
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Definition
Maintaining cell membrane Protection Allowing movement in/out cell |
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Term
What is the function of organelle membranes? |
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Definition
Seperate organelle from rest of cell |
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Term
Term: Organelle that is the site of DNA/RNA synthesis |
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Definition
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Term
True/False: Each somatic cell's DNA's genetic info is a little different |
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Definition
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Term
Term: Sum of all genes in cell |
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Definition
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Term
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Definition
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|
Term
What are the three types of RNA? |
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Definition
Messenger RNA (mRNA) Transfer RNA (tRNA) Ribosomal RNA (rRNA) |
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Term
What is the function of mRNA? |
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Definition
Information; which amino acid added; sequence |
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Term
What is the function of tRNA? |
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Definition
Brings certain amino acid to ribosome |
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Term
What is the function of rRNA? |
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Definition
Add proteins; form ribosomes |
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Term
What is the function of the nuclear pores? |
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Definition
Allow molecules to pass in/out of nucleus |
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Term
Term: Small molecules in cytosol that make up macromolecules to provide cell functions |
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Definition
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|
Term
What are the two types of endoplasmic reticulum? |
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Definition
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|
Term
What is the function of rough ER? |
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Definition
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|
Term
What is the function of smooth ER? |
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Definition
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|
Term
What is the function of secretory vesicles in the golgi apparatus? |
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Definition
They carry macromolecules to the cell membrane, and fuse to it for exocytosis |
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Term
What are the two types of endocytosis? |
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Definition
Phagocytosis (cell eating) Pinocytosis (cell drinking) |
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Term
Term: Enzymes that use oxygen to remove wastes in cell |
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Definition
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Term
Term: Powerhouse of cell; has double membrane; uses O2 and food to form ATP |
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Definition
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|
Term
What are the three types of protein fibers in the cytoskeleton? |
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Definition
Microfilaments Intermediate filaments Microtubules |
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Term
Term: Period of cell growth, protein synthesis, DNA replication |
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Definition
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|
Term
Term: Period of somatic cell division PMAT |
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Definition
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|
Term
True/False: In mitosis, each daughter cell is an exact copy of parent cell |
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Definition
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Term
Term: Cancerous cells form these bunches of cells |
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Definition
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|
Term
True/False: K+ ions are about 10x higher in concentration inside than outside the cell |
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Definition
False, they are about 25x |
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Term
The membrane of the fluid mosaic model is mainly made of what two components? |
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Definition
50% mass Phospholipids 50% mass Proteins |
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Term
Term: Double layer of phospholipids |
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Definition
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Term
Term: Protein embedded in lipid bilayer |
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Definition
Intregal/transmembrane protein |
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Term
Term: Phospholipid bilayer with hydrophilic heads and hydrophobic tails |
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Definition
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|
Term
What provides stabilization of the phospholipids of the cell membrane? |
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Definition
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|
Term
What are the two types of proteins of the cell membrane? |
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Definition
Integral/Transmembrane Extrinsic/Peripheral |
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Term
Term: Protein that does not span cell membrane |
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Definition
Extrinsic/Peripheral protein |
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Term
Are carbohydrates hydrophilic or -phobic? |
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Definition
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|
Term
How much of the phospholipid bilayer is made of carbohydrate? |
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Definition
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|
Term
What are the main types of carbohydrates found in the cell membrane? |
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Definition
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|
Term
What is the function of the carbohydrates in the cell membrane? |
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Definition
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|
Term
Term: Movement through membrane that occurs with concentration gradient, producing less concentrated fluid by diffusion |
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Definition
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|
Term
What are the two major types of movement through membranes? |
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Definition
Passive transport Active transport |
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Term
Term: Type of movement against concentration gradient that forms a more concentrated fluid and requires energy and a protein |
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Definition
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|
Term
Term: Movement from 1 area to a second by random thermal motion |
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Definition
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|
Term
Term: From higher area to lower concentration |
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Definition
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|
Term
Term: Concentrations become equal after movement across a membrane |
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Definition
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|
Term
What is the magnitude of net flux equal to? |
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Definition
J = PA(Co-Ci)
J: Magnitude of net flux P: Permeability constant A: Surface area of membrane Co-Ci: Concentration difference across membrane |
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Term
Term: Movement through membrane of a substance without energy or protein |
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Definition
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|
Term
What does a 'mediated' transport system mean? |
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Definition
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|
Term
Term: Movement across membrane in which a substance requires a protein but no energy |
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Definition
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|
Term
What is the main barrier to most solutes? |
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Definition
Simple diffusion; too difficult to get through phospholipid bilayer |
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Term
Give an example of some lipid insoluble substances |
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Definition
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|
Term
Describe facilitated diffusion vs. simple diffusion |
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Definition
Much faster transport of solutes Saturable process (limit to rate) Highly specific (protein carrier) Can be blocked by competitive inhibitor |
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Term
Term: Related competitors compete for the same binding sites, slowing the transport of desired molecules |
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Definition
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|
Term
Active transport will continue as long as what? |
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Definition
Energy and solute are available |
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|
Term
What is the function of the Sodium/Potassium-ATPase pump? |
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Definition
Energy drives the transport of both sodium (pumped out) and potassium (pumped in) against gradients to maintain the high potassium, low sodium concentration in cytoplasm |
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|
Term
For every ATP split by the Sodium/Potassium-ATPase pump, how many sodium ions and potassium ions are moved? |
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Definition
3 sodium in 2 potassium out |
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|
Term
How are cells differentiated? |
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Definition
Producing different proteins, and not others |
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|
Term
What is the function of pancreatic cells? |
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Definition
Synthesize abundant insulin, but no hemoglobin |
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Term
Term: Selective use of DNA |
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Definition
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|
Term
Where does transcription occur? |
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Definition
|
|
Term
What are the pairs of each base? ATCG |
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Definition
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|
Term
How many different codes do the codons make up? |
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Definition
61 amino acids 3 stop codons |
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Term
True/False: The genetic code is universal |
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Definition
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|
Term
True/False: In semi-conservative replication, 1 strand of DNA serves as the template |
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Definition
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|
Term
What is the function of DNA polymerase? |
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Definition
Enzyme that catalizes DNA replication |
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|
Term
How is RNA edited after transcription? |
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Definition
Pre-RNA exons are cut and spliced, introns are removed, a 5' cap is added as well as a poly-A tail |
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|
Term
What is the function of tRNA? |
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Definition
Brings individual amino acid to ribosome, lock in place, peptide bond formed between adjacent amino acids |
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|
Term
What are the three steps in protein synthesis? |
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Definition
Initiation Elongation Termination |
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Term
Describe the steps in initiation |
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Definition
Synthesis starts with AUG start codon near 5' cap, the small subunit binds to the large subunit and the first tRNA occupies the P-site, the A-site if left vacant |
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|
Term
Describe the steps in elongation |
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Definition
Second tRNA with amino acid enters A-site, the anticodon plugs in, a peptide bond is formed between 2 adjacent amino acids, first tRNA leaves and second moves into P site from A site, third tRNA arrives into A-site, this process is repeated |
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|
Term
Describe the steps in termination |
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Definition
When ribosome reaches stop codon, polypeptide breaks off last tRNA, tRNA is released, the A-site is occupied by release factor that triggers breakup of small and large subunits |
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|
Term
Term: Several ribosomes on same mRNA, each makes 1 molecule of same polypeptide |
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Definition
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|
Term
What controls protein synthesis? |
|
Definition
Transcription; genes are turned on and off and permit or restrict RNA polymerase from attaching to promotor of DNA segment |
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|
Term
Term: Another name for substrate |
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Definition
|
|
Term
|
Definition
E-S complex, where the substrate is modified and the enzyme acts as a catalyst |
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|
Term
True/False: Enzyme binding sites can become saturated due to high S concentration |
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Definition
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|
Term
Term: Binding of modulator molecule to regulatory site on allosteric protein changes shape of functional binding site, so changes bind characteristics and activity of protein |
|
Definition
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|
Term
What regulates the activity of allosteric proteins? |
|
Definition
Changing concentrations of modulator molecules |
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|
Term
How do catalysts affect chemical reactions? |
|
Definition
Speed up reactions by lowering activation energy |
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|
Term
Many enzymes require small amount of ____ to bind to enzyme at site other than active site |
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Definition
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|
Term
|
Definition
Trace metals or coenzymes (organic cofactors) |
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|
Term
Which vitamins provide the body with NADH and FADH2? |
|
Definition
NADH - Niacin FADH2 - Riboflavin |
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|
Term
How are EMRs increased by? |
|
Definition
Warmer temperatures in range 0-40 degrees Celsius Increased substrate concentration and enzyme concentration Increased enzyme affinity for S by allosteric modulation |
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|
Term
What is the rate of product formation controlled by in pathways? |
|
Definition
Allosteric modulation of enzyme control of rate-limiting step |
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|
Term
Term: End product energy that binds to an enzyme and inhibits it |
|
Definition
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|
Term
|
Definition
|
|
Term
Term: Energy currency of cell |
|
Definition
|
|
Term
What is the formula for hydrolysis of ATP? |
|
Definition
|
|
Term
What does the energy from catabolism of fuel molecules form? |
|
Definition
|
|
Term
What are three cell processes that require a lot of ATP? |
|
Definition
Protein synthesis Active transport Muscle contraction |
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|
Term
What are the three linked metabolic pathways used to form food into ATP? |
|
Definition
Glycolysis Krebs Cycle Oxidative Phosphorilation |
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|
Term
Is glycolysis anaerobic or aerobic? |
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Definition
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|
Term
True/False: Glycolysis can break down carbs, fats, and proteins |
|
Definition
False, only can break down carbs |
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|
Term
True/False: Krebs and oxidative phosphorilation can break down carbohydrates, fats, and proteins |
|
Definition
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|
Term
Glycolysis is a __ step path |
|
Definition
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|
Term
Which steps of glycolysis use ATP to form Fructose 1,6 diphosphate? |
|
Definition
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|
Term
At what step of glycolysis does C6 split from P-C6-P -> 2C3 |
|
Definition
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|
Term
At which step of glycolysis does an isomerization occur? |
|
Definition
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|
Term
In what step of Glycolysis is NADH formed? |
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Which steps of glycolysis form ATP in substrate level phosphorilation? |
|
Definition
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|
Term
When exercising muscles with low oxygen, which pathway yields 3% of free energy available from glucose? |
|
Definition
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|
Term
1 molecule of glucose yields __ molecules of pyruvate |
|
Definition
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|
Term
In total, Glycolysis yields how many NADH and ATP? |
|
Definition
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|
Term
When pyruvate enters the mitochondria and loses CO2, it becomes what? |
|
Definition
|
|
Term
What happens during the linking step? |
|
Definition
NADH+ -> NADH; C3 -> C2 and CO2 is given off
Acetyl joins coenzyme A and is linked with C4 |
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|
Term
Oxaloacetate + Acetyl-CoA forms...? |
|
Definition
|
|
Term
Krebs regenerates CoA and gives off how many CO2? |
|
Definition
|
|
Term
Oxidations of C2 coupled with reduction of electron-carrying coenzymes NAD+ and FAH to form what? |
|
Definition
High energy reduced forms NADH and FADH2 |
|
|
Term
How many NADH and FADH2 are formed in the Krebs Cycle? |
|
Definition
|
|
Term
What are the products of ADP + GTP ->? |
|
Definition
|
|
Term
How many GTPs are formed during the Krebs cycle? |
|
Definition
|
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Term
___ is essential for oxidation of NADH and FADH2 |
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Definition
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Term
Which steps of the Krebs cycle form NADH? |
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Definition
At C6 -> C5 At C5 -> C4 Forming oxaloacetate |
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Term
Term: Breaking down large objects |
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Definition
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Term
Term: Building up large objects |
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Definition
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Term
Where in the Krebs Cycle is GTP formed? |
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Definition
Between the first two C4s |
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Term
Give a summary of the linking step |
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Definition
Pyruvic acid + CoA + NAD+ -> C2-CoA + CO2 + NADH |
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Term
Give a summary of the Krebs Cycle |
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Definition
2C2-CoA + 2C4 + 2GDP + 6NAD+ + 2FAD -> 2C6 + 2CoA + 2GTP + 6NADH + 2FADH2 |
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Term
What is the harvest of link and krebs? |
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Definition
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Term
Each electron carrier is slightly ___ energy vs. previous |
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Definition
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Term
What is the final electron acceptor? |
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Definition
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Term
Explain the chemiosmotic theory |
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Definition
Protons are pumped out of matrix as electrons are passed down the ETC. As protons go through the ATP synthetase complex, energy is used to form ATP |
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Term
The majority of ATP for cells is made by ___ ___ |
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Definition
Oxidative Phosphorilation |
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Term
What is the difference between fats and other sources of energy? |
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Definition
It is a rich energy source, and gives off 9kcal per gram while carbs and proteins only give off 4kcals per gram |
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Term
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Definition
1 fat -> 1 glycerol + 3 fatty acids |
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Term
Fatty acids have carbon skeletons of what? |
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Definition
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Term
Describe the metabolism of proteins |
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Definition
Proteins -> amino acids, remove NH2, deamination forms NH3 which is toxic, and is converted into urea and excreted |
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Term
After the removal of NH2, what happens to the carbons? |
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Definition
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Term
Acetyl is a precursor in biosynthesis of amino acids, monosaccharides and fatty acids which makes it what? |
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Definition
The point where catabolic and anabolic pathways intersect |
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Term
Messengers are amplified by ___ |
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Definition
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